Adaptive Evolution of Escherichia coli to an α-Peptide/β-Peptoid Peptidomimetic Induces Stable Resistance

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Hein Kristensen, Line ^a   Franzyk, Henrik ^b   Holch, Anne ^a   Gram, Lone ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA PEPTIDE PEPTIDOMIMETIC AGENT; AMPICILLIN; BETA PEPTOID PEPTIDOMIMETIC AGENT; ERYTHROMYCIN; GENTAMICIN; MUREIN TRANSGLYCOSYLASE D; OUTER MEMBRANE PROTEIN; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; PEPTIDOMIMETIC AGENT; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; PROTAMINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL MEMBRANE; CONTROLLED STUDY; CROSS RESISTANCE; ESCHERICHIA COLI; EVOLUTION; MINIMUM INHIBITORY CONCENTRATION; MUTATION; NONHUMAN; PLASMA;

ADAPTATION, PHYSIOLOGICAL; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL INFECTIONS; BACTERIAL OUTER MEMBRANE PROTEINS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION, MOLECULAR; GLYCOSYLTRANSFERASES; HUMANS; INDEL MUTATION; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MOLECULAR STRUCTURE; MUTATION; PEPTIDES; PEPTIDOMIMETICS; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYMYXIN B;

EID: 84883539803     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073620     Document Type: Article

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