A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid

Journal of Bacteriology

Volumn 188, Issue 3, 2006, Pages 1180-1183

  Froelich, Jamie M ^a   Tran, Khoa ^a   Wall, Daniel ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COLISTIN; DEOXYCHOLIC ACID; DNA; POLYMYXIN B;

ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; DELETION MUTANT; ESCHERICHIA COLI; GENE EXPRESSION; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PMRA GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION;

BACTERIAL PROTEINS; DEOXYCHOLIC ACID; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; LIPID A; MUTATION; POLYMYXIN B;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 31344459012     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.188.3.1180-1183.2006     Document Type: Article

References (30)

1. Aguirre, A., S. Lejona, E. G. Vescovi, and F. C. Soncini. 2000. Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar Typhimurium. J. Bacteriol. 182:3874-3876.
2. Bader, M. W., S. Sanowar, M. E. Daley, A. R. Schneider, U. Cho, W. Xu, R. E. Klevit, H. L. Moual, and S. I. Miller. 2005. Recognition of antimicrobial peptides by a bacterial sensor kinase. Cell 122:461-412.
3. Baranova, N., and H. Nikaido. 2002. The BaeSR two-component regulatory system activates transcription of the yegMNOB (mdtABCD) transporter gene cluster in Escherichia coli and increases its resistance to novobiocin and deoxycholate. J. Bacteriol. 184:4168-4176.
4. Chamnongpol, S., W. Dodson, M. J. Cromie, Z. L. Harris, and E. A. Groisman. 2002. Fe(III)-mediated cellular toxicity. Mol. Microbiol. 45:711-719.
5. Dame, J. B., and B. M. Shapiro. 1976. Use of polymyxin B, levallorphan, and tetracaine to isolate novel envelope mutants of Escherichia coli. J. Bacteriol. 127:961-972.
6. Groisman, E. A. 2001. The pleiotropic two-component regulatory system PhoP-PhoQ. J. Bacteriol. 183:1835-1842.
7. Gunn, J. S. 2000. Mechanisms of bacterial resistance and response to bile. Microbes Infect. 2:907-913.
8. Hagiwara, D., T. Yamashino, and T. Mizuno. 2004. A genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses. Biosci. Biotechnol. Biochem. 68:1758-1767.
9. Lee, H., F. F. Hsu, J. Turk, and E. A. Groisman. 2004. The PmrA-regulated pmrC gene mediates phosphoethanolamine modification of lipid A and polymyxin resistance in Salmonella enterica. J. Bacteriol. 186:4124-4133.
10. Lee, L. J., J. A. Barrett, and P. K. Poole. 2005. Genome-wide transcriptional response of chemostat-cultured Escherichia coli to zinc. J. Bacteriol. 187:1124-1134.
11. Lorian, V. 1996. Antibiotics in laboratory medicine, 4th ed. Williams and Wilkins. Baltimore, Md.
12. Macfarlane, E. L., A. Kwasnicka, and R. E. W. Hancock. 2000. Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides. Microbiology 146:2543-2554.
13. Male, M. S., and R. E. Loughlin. 1998. Promoter-detection vectors for Escherichia coli with multiple useful features. Gene 64:207-215.
14. Marchal, K., S. De Keersmaecker, P. Monsieurs, N. van Boxel, K. Lemmens, G. Thijs, J. Vanderleyden, and B. De Moor. 29 January 2004, posting date. In silico identification and experimental validation of PmrAB targets in Salmonella typhimurium by regulatory motif detection. Genome Biol. 5:R9. [Online.] http://genomebiology.com/2004/5/2/R9.
15. Miller, J. H. 1992. A short course in bacterial genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
16. Miller, S. I., R. K. Ernst, and M. W. Bader. 2005. LPS, TLR4 and infectious disease diversity. Nat. Rev. Microbiol. 3:36-46.
17. Nichols, B. P., O. Shafiq, and V. Meiners. 1998. Sequence analysis of Tn10 insertion sites in a collection of Escherichia coli strains used for genetic mapping and strain construction. J. Bacteriol. 180:6408-6411.
18. Nikaido, H. 2003. Molecular basis of bacterial outer membrane permeability revisited. Microbiol. Mol. Biol. Rev. 67:593-656.
19. Roland, K. L., L. E. Martin, C. R. Esther, and J. K. Spitznagel. 1993. Spontaneous pmrA mutants of Salmonella typhimurium LT2 define a new two-component regulatory system with a possible role in virulence. J. Bacteriol. 175:4154-4164.
20. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
21. E-dependent response in Escherichia coli. Mol. Microbiol. 55:1403-1412.
22. Tamayo, R., A. G. Prouty, and J. S. Gunn. 2005. Identification and functional analysis of Salmonella enterica serovar Typhimurium PmrA-regulated genes. FEMS Immunol. Med. Microbiol. 43:249-258.
23. Tamayo, R., S. S. Ryan, A. J. McCoy, and J. S. Gunn. 2002. Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar Typhimurium. Infect. Immun. 70:6770-6778.
24. Trent, M. S., A. A. Ribeiro, W. T. Doerrler, S. Lin, R. J. Cotter, and C. R. H. Raetz. 2001. Accumulation of a polyisoprene-linked amino sugar in polymyxin-resistant Salmonella typhimurium and Escherichia coli. J. Biol. Chem. 276:43132-43144.
25. Trent, M. S., A. A. Ribeiro, S. Lin, R. J. Cotter, and C. R. H. Raetz. 2001. An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A. J. Biol. Chem. 276:43122-43131.
26. Van Velkinburgh, J. C., and J. S. Gunn. 1999. PhoP-PhoQ-regulated loci are required for enhanced bile resistance in Salmonella spp. Infect. Immun. 67:1614-1622.
27. Winfield, M. D., and E. A. Groisman. 2004. Phenotypic differences between Salmonella and Escherichia coli resulting from the disparate regulation of homologous genes. Proc. Natl. Acad. Sci. USA 101:17162-17167.
28. Wosten, M. M., L. F. Kox, S. Chamnongpol, F. C. Soncini, and E. A. Groisman. 2000. A signal transduction system that responds to extracellular iron. Cell 103:113-125.
29. Zhang, Y., F. Buchholz, J. P. P. Muryrers, and A. S. Stewart. 1998. A new logic for DNA engineering using recombination in Escherichia coli. Nat. Genet. 20:123-128.
30. 3 in Escherichia coli K12. J. Biol. Chem. 274:18503-18514.