The role of the central L- or D-Pro residue on structure and mode of action of a cell-selective α-helical IsCT-derived antimicrobial peptide

Biochemical and Biophysical Research Communications

Volumn 334, Issue 4, 2005, Pages 1329-1335

  Shin, Saeng Lim ^a   Kim, Yangmee ^b   Park, Yoonkyung ^a   Jae, Il Kim ^c   Park, Il Seon ^a   Hahm, Kyung Soo ^a   Song, Yub Shin ^a  

^a Chosun University   (South Korea)

^b Konkuk University   (South Korea)

^c Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

helical antimicrobial peptide; Bacterial membranes; Cell selectivity; D Pro kink; Intracellular components; IsCT; L Pro kink; Mechanism; Potential depolarization; Structure

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; LIPOSOME; PROLINE;

ALPHA HELIX; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL MEMBRANE; CELL SELECTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DEPOLARIZATION; DRUG MECHANISM; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; STAPHYLOCOCCUS AUREUS; SUBSTITUTION REACTION;

ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ERYTHROCYTES; ESCHERICHIA COLI; HEMOLYSIS; HUMANS; ISOMERISM; MEMBRANE FLUIDITY; SCORPION VENOMS; STRUCTURE-ACTIVITY RELATIONSHIP;

SCORPIONES; STAPHYLOCOCCUS AUREUS;

EID: 23044494735     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.07.029     Document Type: Article

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