메뉴 건너뛰기




Volumn 33, Issue 17, 2013, Pages 3482-3493

CTGF Mediates Smad-Dependent Transforming Growth Factor β Signaling To Regulate Mesenchymal Cell Proliferation during Palate Development

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CONNECTIVE TISSUE GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84883494670     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00615-13     Document Type: Article
Times cited : (58)

References (63)
  • 1
    • 80054058498 scopus 로고    scopus 로고
    • The mechanism of TGF-β signaling during palate development
    • Iwata J, Parada C, Chai Y. 2011. The mechanism of TGF-β signaling during palate development. Oral Dis. 17:733-744.
    • (2011) Oral Dis. , vol.17 , pp. 733-744
    • Iwata, J.1    Parada, C.2    Chai, Y.3
  • 3
    • 0031973930 scopus 로고    scopus 로고
    • Classification and birth prevalence of orofacial clefts
    • Tolarová MM, Cervenka J. 1998. Classification and birth prevalence of orofacial clefts. Am. J. Med. Genet. 75:126-137.
    • (1998) Am. J. Med. Genet. , vol.75 , pp. 126-137
    • Tolarová, M.M.1    Cervenka, J.2
  • 5
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-beta3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. 1995. Abnormal lung development and cleft palate in mice lacking TGF-beta3 indicates defects of epithelial-mesenchymal interaction. Nat. Genet. 11:415-421.
    • (1995) Nat. Genet. , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6    Groffen, J.7
  • 8
    • 78049287216 scopus 로고    scopus 로고
    • The Loeys-Dietz syndrome: an update for the clinician
    • Van Hemelrijk C, Renard M, Loeys B. 2010. The Loeys-Dietz syndrome: an update for the clinician. Curr. Opin. Cardiol. 25:546-551.
    • (2010) Curr. Opin. Cardiol. , vol.25 , pp. 546-551
    • Van Hemelrijk, C.1    Renard, M.2    Loeys, B.3
  • 9
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • Shi Y, Massagué J. 2003. Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massagué, J.2
  • 10
    • 84857890422 scopus 로고    scopus 로고
    • Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice
    • Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y. 2012. Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. J. Clin. Invest. 122:873-885.
    • (2012) J. Clin. Invest. , vol.122 , pp. 873-885
    • Iwata, J.1    Hacia, J.G.2    Suzuki, A.3    Sanchez-Lara, P.A.4    Urata, M.5    Chai, Y.6
  • 11
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-beta signals
    • Massague J. 2000. How cells read TGF-beta signals. Nat. Rev. Mol. Cell Biol. 1:169-178.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 169-178
    • Massague, J.1
  • 12
    • 48549093346 scopus 로고    scopus 로고
    • Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/ BMP signaling during tooth and palate development
    • Xu X, Han J, Ito Y, Bringas P, Jr, Deng C, Ch ai Y. 2008. Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/ BMP signaling during tooth and palate development. Dev. Cell 15:322-329.
    • (2008) Dev. Cell , vol.15 , pp. 322-329
    • Xu, X.1    Han, J.2    Ito, Y.3    Bringas Jr., P.4    Deng, C.5    Chai, Y.6
  • 13
    • 59649107705 scopus 로고    scopus 로고
    • Functions and mechanisms of action of CCN matricellular proteins
    • Chen C-C, Lau LF. 2009. Functions and mechanisms of action of CCN matricellular proteins. Int. J. Biochem. Cell Biol. 41:771-783.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 771-783
    • Chen, C.-C.1    Lau, L.F.2
  • 14
    • 65849445411 scopus 로고    scopus 로고
    • Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc?
    • Abraham D. 2008. Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSc?. Rheumatology 47:v8 -v9.
    • (2008) Rheumatology , vol.47 , pp. 8-9
    • Abraham, D.1
  • 18
    • 0034971702 scopus 로고    scopus 로고
    • The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts
    • Leask A, Sa S, Holmes A, Shiwen X, Black CM, Abraham DJ. 2001. The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts. Mol. Pathol. 54:180-183.
    • (2001) Mol. Pathol. , vol.54 , pp. 180-183
    • Leask, A.1    Sa, S.2    Holmes, A.3    Shiwen, X.4    Black, C.M.5    Abraham, D.J.6
  • 19
    • 0036051343 scopus 로고    scopus 로고
    • Connectivetissue growth factor (CTGF) modulates cell signalling by BMP and TGFbeta
    • Abreu JG, Ketpura NI, Reversade B, De Robertis EM. 2002. Connectivetissue growth factor (CTGF) modulates cell signalling by BMP and TGFbeta. Nat. Cell Biol. 4:599-604.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 21
    • 2542631834 scopus 로고    scopus 로고
    • Connective-tissue growth factor modulatesWNTsignalling and interacts with the WNT receptor complex
    • Mercurio S, Latinkic B, Itasaki N, Krumlauf R, Smith JC. 2004. Connective-tissue growth factor modulatesWNTsignalling and interacts with the WNT receptor complex. Development 131:2137-2147.
    • (2004) Development , vol.131 , pp. 2137-2147
    • Mercurio, S.1    Latinkic, B.2    Itasaki, N.3    Krumlauf, R.4    Smith, J.C.5
  • 24
    • 33846920850 scopus 로고    scopus 로고
    • The role of TGF-β signaling in regulating chondrogenesis and osteogenesis during mandibular development
    • Oka K, Oka S, Sasaki T, Ito Y, Bringas P, Jr, Nonaka K, Chai Y. 2007. The role of TGF-β signaling in regulating chondrogenesis and osteogenesis during mandibular development. Dev. Biol. 303:391-404.
    • (2007) Dev. Biol. , vol.303 , pp. 391-404
    • Oka, K.1    Oka, S.2    Sasaki, T.3    Ito, Y.4    Bringas Jr., P.5    Nonaka, K.6    Chai, Y.7
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 delta delta CT method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 delta delta CT method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 84856069817 scopus 로고    scopus 로고
    • Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis
    • Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y. 2012. Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J. Biol. Chem. 287:2353-2363.
    • (2012) J. Biol. Chem. , vol.287 , pp. 2353-2363
    • Iwata, J.1    Tung, L.2    Urata, M.3    Hacia, J.G.4    Pelikan, R.5    Suzuki, A.6    Ramenzoni, L.7    Chaudhry, O.8    Parada, C.9    Sanchez-Lara, P.A.10    Chai, Y.11
  • 27
    • 0028971143 scopus 로고
    • MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data
    • Quandt K, Frech K, Karas H, Wingender E, Werner T. 1995. MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:4878-4884.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4878-4884
    • Quandt, K.1    Frech, K.2    Karas, H.3    Wingender, E.4    Werner, T.5
  • 30
    • 0036775477 scopus 로고    scopus 로고
    • Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?
    • Blom IE, Goldschmeding R, Leask A. 2002. Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? Matrix Biol. 21:473-482.
    • (2002) Matrix Biol , vol.21 , pp. 473-482
    • Blom, I.E.1    Goldschmeding, R.2    Leask, A.3
  • 32
    • 0034695690 scopus 로고    scopus 로고
    • Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone
    • Zhu T, Lobie PE. 2000. Janus kinase 2-dependent activation of p38 mitogen-activated protein kinase by growth hormone. J. Biol. Chem. 275: 2103-2114.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2103-2114
    • Zhu, T.1    Lobie, P.E.2
  • 34
    • 0036714198 scopus 로고    scopus 로고
    • Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis
    • Zhang Z, Song Y, Zhao X, Zhang X, Fermin C, Chen Y. 2002. Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis. Development 129:4135-4146.
    • (2002) Development , vol.129 , pp. 4135-4146
    • Zhang, Z.1    Song, Y.2    Zhao, X.3    Zhang, X.4    Fermin, C.5    Chen, Y.6
  • 35
    • 43349098174 scopus 로고    scopus 로고
    • Connective tissue growth factor stimulates renal cortical myofibroblast-like cell proliferation and matrix protein production
    • Gao X, Li J, Huang H, Li X. 2008. Connective tissue growth factor stimulates renal cortical myofibroblast-like cell proliferation and matrix protein production. Wound Repair Regen. 16:408-415.
    • (2008) Wound Repair Regen. , vol.16 , pp. 408-415
    • Gao, X.1    Li, J.2    Huang, H.3    Li, X.4
  • 36
    • 0033988962 scopus 로고    scopus 로고
    • CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts
    • Kothapalli D, Grotendorst GR. 2000. CTGF modulates cell cycle progression in cAMP-arrested NRK fibroblasts. J. Cell. Physiol. 182:119-126.
    • (2000) J. Cell. Physiol. , vol.182 , pp. 119-126
    • Kothapalli, D.1    Grotendorst, G.R.2
  • 37
    • 75749131647 scopus 로고    scopus 로고
    • Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies
    • Rosenbloom J, Castro SV, Jimenez SA. 2010. Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann. Intern. Med. 152:159-166.
    • (2010) Ann. Intern. Med. , vol.152 , pp. 159-166
    • Rosenbloom, J.1    Castro, S.V.2    Jimenez, S.A.3
  • 41
    • 33646102224 scopus 로고    scopus 로고
    • Expression and regulation of CCN genes in murine osteoblasts
    • Parisi MS, Gazzerro E, Rydziel S, Canalis E. 2006. Expression and regulation of CCN genes in murine osteoblasts. Bone 38:671-677.
    • (2006) Bone , vol.38 , pp. 671-677
    • Parisi, M.S.1    Gazzerro, E.2    Rydziel, S.3    Canalis, E.4
  • 42
    • 0033826990 scopus 로고    scopus 로고
    • Transcriptional regulation of connective tissue growth factor by cortisol in osteoblasts
    • Pereira RC, Durant D, Canalis E. 2000. Transcriptional regulation of connective tissue growth factor by cortisol in osteoblasts. Am. J. Physiol. Endocrinol. Metab. 279:E570-E576.
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.279
    • Pereira, R.C.1    Durant, D.2    Canalis, E.3
  • 43
    • 17644402750 scopus 로고    scopus 로고
    • Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases
    • Shimo T, Koyama E, Sugito H, Wu C, Shimo S, Pacifici M. 2005. Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases. J. Bone Miner. Res. 20:867-877.
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 867-877
    • Shimo, T.1    Koyama, E.2    Sugito, H.3    Wu, C.4    Shimo, S.5    Pacifici, M.6
  • 46
    • 0037757793 scopus 로고    scopus 로고
    • Role of Smad4 (DPC4) inactivation in human cancer
    • Miyaki M, Kuroki T. 2003. Role of Smad4 (DPC4) inactivation in human cancer. Biochem. Biophys. Res. Commun. 306:799-804.
    • (2003) Biochem. Biophys. Res. Commun. , vol.306 , pp. 799-804
    • Miyaki, M.1    Kuroki, T.2
  • 49
    • 0031454239 scopus 로고    scopus 로고
    • Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGFbeta1 transgenic mice
    • Clouthier DE, Comerford SA, Hammer RE. 1997. Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGFbeta1 transgenic mice. J. Clin. Invest. 100:2697-2713.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2697-2713
    • Clouthier, D.E.1    Comerford, S.A.2    Hammer, R.E.3
  • 50
    • 77953808712 scopus 로고    scopus 로고
    • Potential therapeutic targets for cardiac fibrosis
    • Leask A. 2010. Potential therapeutic targets for cardiac fibrosis. Circ. Res. 106:1675-1680.
    • (2010) Circ. Res. , vol.106 , pp. 1675-1680
    • Leask, A.1
  • 51
    • 0038622956 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo
    • Safadi FF, Xu J, Smock SL, Kanaan RA, Selim A-H, Odgren PR, Marks SC, Owen TA, Popoff SN. 2003. Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo. J. Cell. Physiol. 196:51-62.
    • (2003) J. Cell. Physiol. , vol.196 , pp. 51-62
    • Safadi, F.F.1    Xu, J.2    Smock, S.L.3    Kanaan, R.A.4    Selim, A.-H.5    Odgren, P.R.6    Marks, S.C.7    Owen, T.A.8    Popoff, S.N.9
  • 52
    • 67349178647 scopus 로고    scopus 로고
    • Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells
    • Junglas B, Yu AHL, Welge-Luessen U, Tamm ER, Fuchshofer R. 2009. Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells. Exp. Eye Res. 88:1065-1075.
    • (2009) Exp. Eye Res. , vol.88 , pp. 1065-1075
    • Junglas, B.1    Yu, A.H.L.2    Welge-Luessen, U.3    Tamm, E.R.4    Fuchshofer, R.5
  • 53
    • 75549086340 scopus 로고    scopus 로고
    • Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin
    • Quan T, Shao Y, He T, Voorhees JJ, Fisher GJ. 2010. Reduced expression of connective tissue growth factor (CTGF/CCN2) mediates collagen loss in chronologically aged human skin. J. Invest. Dermatol. 130:415-424.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 415-424
    • Quan, T.1    Shao, Y.2    He, T.3    Voorhees, J.J.4    Fisher, G.J.5
  • 55
    • 67349168833 scopus 로고    scopus 로고
    • Connective tissue growth factor: context-dependent functions and mechanisms of regulation
    • Cicha I, Goppelt-Struebe M. 2009. Connective tissue growth factor: context-dependent functions and mechanisms of regulation. BioFactors 35: 200-208.
    • (2009) BioFactors , vol.35 , pp. 200-208
    • Cicha, I.1    Goppelt-Struebe, M.2
  • 56
    • 0141527497 scopus 로고    scopus 로고
    • Transcriptional induction of connective tissue growth factor/ hypertrophic chondrocyte-specific 24 gene by dexamethasone in human chondrocytic cells
    • Kubota S, Moritani NH, Kawaki H, Mimura H, Minato M, Takigawa M. 2003. Transcriptional induction of connective tissue growth factor/ hypertrophic chondrocyte-specific 24 gene by dexamethasone in human chondrocytic cells. Bone 33:694-702.
    • (2003) Bone , vol.33 , pp. 694-702
    • Kubota, S.1    Moritani, N.H.2    Kawaki, H.3    Mimura, H.4    Minato, M.5    Takigawa, M.6
  • 57
    • 0035207024 scopus 로고    scopus 로고
    • CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK)
    • Yosimichi G, Nakanishi T, Nishida T, Hattori T, Takano-Yamamoto T, Takigawa M. 2001. CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK). Eur. J. Biochem. 268:6058-6065.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 6058-6065
    • Yosimichi, G.1    Nakanishi, T.2    Nishida, T.3    Hattori, T.4    Takano-Yamamoto, T.5    Takigawa, M.6
  • 59
    • 29944440874 scopus 로고    scopus 로고
    • Lipoxin A4 inhibits proliferation of human lung fibroblasts induced by connective tissue growth factor
    • Wu S-H, Wu X-H, Lu C, Dong L, Chen Z-Q. 2006. Lipoxin A4 inhibits proliferation of human lung fibroblasts induced by connective tissue growth factor. Am. J. Respir. Cell Mol. Biol. 34:65-72.
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.34 , pp. 65-72
    • Wu, S.-H.1    Wu, X.-H.2    Lu, C.3    Dong, L.4    Chen, Z.-Q.5
  • 61
    • 33748296370 scopus 로고    scopus 로고
    • Recent advances in craniofacial morphogenesis
    • Chai Y, Maxson RE, Jr. 2006. Recent advances in craniofacial morphogenesis. Dev. Dyn. 235:2353-2375.
    • (2006) Dev. Dyn. , vol.235 , pp. 2353-2375
    • Chai, Y.1    Maxson, R.E.Jr.2
  • 62
    • 20444504753 scopus 로고    scopus 로고
    • Structural and functional properties of CCN proteins
    • Rachfal AW, Brigstock DR. 2005. Structural and functional properties of CCN proteins. Vitam. Horm. 70:69-103.
    • (2005) Vitam. Horm. , vol.70 , pp. 69-103
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 63
    • 69349096425 scopus 로고    scopus 로고
    • Transforming growth factor-β1 up-regulation of human α1(I) collagen is mediated by Sp1 and Smad2 transacting factors
    • Sysa P, Potter JJ, Liu X, Mezey E. 2009. Transforming growth factor-β1 up-regulation of human α1(I) collagen is mediated by Sp1 and Smad2 transacting factors. DNA Cell Biol. 28:425-434.
    • (2009) DNA Cell Biol. , vol.28 , pp. 425-434
    • Sysa, P.1    Potter, J.J.2    Liu, X.3    Mezey, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.