Transforming growth factor-β1 up-regulation of human α1(I) collagen is mediated by Sp1 and Smad2 transacting factors

DNA and Cell Biology

Volumn 28, Issue 9, 2009, Pages 425-434

  Sysa, Polina ^a   Potter, James J ^a   Liu, Xiaopu ^a   Mezey, Esteban ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; SMAD2 PROTEIN; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; STELLATE CELL; UPREGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; COLLAGEN TYPE I; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FIBROBLASTS; HEPATIC STELLATE CELLS; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA, SMALL INTERFERING; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SP1 TRANSCRIPTION FACTOR; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 69349096425     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2009.0884     Document Type: Article

References (30)

1. Aparicio, O., Geisberg, J.V., Sekinger, E., Yang, A., Moqtaderi, Z., and Struhl, K. (2005). Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Curr Protoc Mol Biol Chapter 21, 21.3.1-21.3.33.
2. Attisano, L., and Wrana, J.L. (2002). Signal transduction by the TGF-β superfamilty. Science 296, 1646-1647.
3. 1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro. Gene 215, 101-110.
4. 2 (I) procollagen gene promoter required for transcriptional activation of TGF-β. J Cell Physiol 183, 381-392.
5. Di Nocera, P.P., and David, I.B. (1983). Transient expression of genes introduced into cultured cells in Drosophila. Proc Natl Acad Sci USA 80, 7095-7098.
6. Docagne, F., Gabriel, C., Lebeurrier, N., Lesne, S., Hommet, Y., Plawinski, L., Mackenzie, E.T., and Vivien, D. (2004). Sp1 and Smad transcription factors cooperate to mediate TGF-β-dependent activation of amyloid-β precursor protein gene transcription. Biochem J 383, 383-399. (Pubitemid 39446701)
7. Evans, P.M., Zhang, W., Chen, X., Yang, J., Bhakat, K., and Liu, C. (2007). Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J Biol Chem 282, 33994-34002. (Pubitemid 350159428)
8. Feinberg, A.P., and Vogelstein, B. (1983). A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132, 6-13.
9. Gaidarova, S., and Jimenez, S.A. (2002). Inhibition of basal and transforming growth factor-β-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts. J Biol Chem 277, 38737-38745. (Pubitemid 35154736)
10. Ghosh, A.K., Yuan, W., Mori, Y., Chen, S.J., and Varga, J. (2001). Antagonistic regulation of type I collagen gene expression by interferon-γ and transforming growth factor-β. Integration at the level of p300/CP transcriptional coactivators. J Biol Chem 276, 11041-11048. (Pubitemid 38089285)
11. Grinberg, A.V., and Kerppola, T. (2003). Both Max and TFB3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter but they have opposite effects on trasncriptional activity. J Biol Chem 278, 11227-11236.
12. Ho, S.N., Hunt, H.D., Horton, R.M., Pullen, J.K., and Pease, L.R. (1989). Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59. (Pubitemid 19125653)
13. 1(I) procollagen gene promoter. Differential activity in collagen-producing and-nonproducing cells and response to transforming growth factor b1. J Biol Chem 269, 12684-12691.
14. Kypriotou, M., Beauchef, G., Chadjichristos, C., Widom, R., Renard, E., Jimenez, S.A., Korn, J., Maquart, F.X., Oddos, T., Von Stetten, O., Pujol, J.P., and Galera, P. (2007). Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors. J Biol Chem 282, 32000-32014. (Pubitemid 350106419)
15. Labbe, E., Silvestri, C., Hoodless, P.A., Wrana, J.L., and Attisano, L. (1988). Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST2. Mol Cell 2, 109-120.
16. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193, 265-275.
17. Moustakas, A., and Kardassis, D. (1998). Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc Natl Acad Sci USA 95, 6733-6738. (Pubitemid 28278049)
18. 1(I) gene expression. DNA Cell Biol 11, 443-452.
19. Nowak, D.E., Tian, B., and Brasier, A.R. (2005). Two-step cross-linking method for identification of NF-KappaB gene network by chromatin immunoprecipitation. Biotechniques 39, 715-724.
20. Panish, M.K., Wahab, N.A., Colville-Nash, P., Hendry, B.M., and Dockrell, M.E.C. (2006). The differential role of Smad2 and Smad3 in the regulation of profibrotic TGFβ1 responses in human proximal-tubule epithelial cells. Biochem J 393, 601-607. (Pubitemid 43099100)
21. Pardali, K., Kurisaki, A., Moren, A., ten Dijke, P., Kardassis, D., and Moustakas, A. (2000). Role of Smad proteins and transcription factor Sp1 in p21Waf1/Cip1 regulation by transforming growth factor-β. J Biol Chem 275, 29244-29256.
22. 2(I) collagen expression in human glomerular mesagial cells. J Biol Chem 276, 6983-6992.
23. Potter, J.J., Mezey, E., Christy, R.J., Crabb, D.W., Stein, P.M., and Yang, V.W. (1991). CCAAT/enhancer binding protein binds and activates the promoter to the rat class I alcohol dehydrogenase gene. Arch Biochem Biophys 285, 246-251.
24. Roberts, A.B. (2002). The ever-increasing complexity of TGF-β signaling. Cytokine Growth Factor Rev 13, 3-5.
25. Shi, Y., Wang, Y.F., Jayaraman, L., Yang, H., Massague, J., and Pavletich, N.P. (1998). Crystal structure of a SmadMH1 domain bound to DNA: insights on DNA binding in TGF-β signaling. Cell 94, 585-594. (Pubitemid 28427577)
26. 2(I) collagen promoter by leptin in not mediated by transforming growth factor β responsive elements. Biochem Biophys Res Commun 31, 629-633.
27. Widom, R.L., Culic, I., Lee, J.Y., and Korn, J.H. (1997). Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix expression. Gene 198, 407-420. (Pubitemid 27453770)
28. Wrana, J.L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X.F., and Massague, J. (1992). TGFβ signals through a heteromeric protein kinase receptor complex. Cell 71, 1003-1014.
29. 2(I)-collagen (COL1A2) transcription. J Biol Chem 275, 39237-39245.
30. Zhang, X., Yang, J., Li, Y., and Liu, Y. (2005). Both Sp1 and Smad participate in mediating TGF-β1-induced HGF receptor expression in renal epithelial cells. Am J Physiol Renal Physiol 288, F16-F26. (Pubitemid 40038672)