IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C

FEBS Letters

Volumn 587, Issue 18, 2013, Pages 3014-3020

  Moore, Tyler C ^a,b   Petro, Thomas M ^b,c  

^a UNIVERSITY OF NEBRASKA   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

ERK MAP kinase; Interferon response factor 3; Interleukin 6; Macrophages; Nitric oxide; Poly I:C

Indexed keywords

BETA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE R; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE INACTIVATION; GENE SILENCING; INTRACELLULAR SIGNALING; MACROPHAGE CULTURE; MOLECULAR DYNAMICS; MOUSE; NITRIC OXIDE PRODUCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

BL/6; C57BL/6 MICE; ERK; ERK MAP-KINASE; EXTRACELLULAR SIGNAL RELATED KINASE; INTERFERON RESPONSE FACTOR 3; INTERFERON RESPONSE FACTOR-3; INTERLEUKIN-6; IRF3; IRF3 DEFICIENT MICE; IRF3KO; LIPOPOLYSACCHARIDE; LPS; MACROPHAGES; NF-ΚB; NITRIC OXIDE; NO; NUCLEAR FACTOR Κ-B; ODN; OLIGODEOXYNUCLEOTIDE; PHOSPHOINOSITIDE-3-KINASE; PI3K; PKR; POLY I:C; PROTEIN KINASE R; TIR; TIR DOMAIN-CONTAINING ADAPTOR-INDUCING IFN-Β; TLR; TOLL LIKE RECEPTOR; TOLL/IL-1 RECEPTOR; TRIF;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NITRIC OXIDE; POLY I-C; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION;

RNA VIRUSES;

EID: 84883488875     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.07.025     Document Type: Article

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