Cystic fibrosis transmembrane conductance regulator degradation: Cross-talk between the ubiquitylation and SUMOylation pathways

FEBS Journal

Volumn 280, Issue 18, 2013, Pages 4430-4438

  Ahner, Annette ^a   Gong, Xiaoyan ^a   Frizzell, Raymond A ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

cystic fibrosis transmembrane conductance regulator; degradation; endoplasmic reticulum associated; Hsp27; proteasome; quality control; small heat shock proteins; small ubiquitin like modifier; STUbL; ubiquitin

Indexed keywords

CHAPERONE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; PROTEASOME; PROTEIN RNF4; PROTEIN UBC9; SMALL HEAT SHOCK PROTEIN; SUMO PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG;

BIOGENESIS; CELLULAR DISTRIBUTION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME MECHANISM; HUMAN; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEIN TRANSPORT; QUALITY CONTROL; REVIEW; SUMOYLATION; UBIQUITINATION;

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DEGRADATION; ENDOPLASMIC RETICULUM ASSOCIATED; HSP27; PROTEASOME; QUALITY CONTROL; SMALL HEAT SHOCK PROTEINS; SMALL UBIQUITIN-LIKE MODIFIER; STUBL; UBIQUITIN;

CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HSP27 HEAT-SHOCK PROTEINS; HUMANS; MUTATION; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEOLYSIS; SIGNAL TRANSDUCTION; SUMOYLATION; TRANSCRIPTION FACTORS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84883453931     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12415     Document Type: Review

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