-
1
-
-
84868642198
-
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcgammaRIIB and dectin-1
-
Karsten CM, Pandey MK, Figge J et al. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcgammaRIIB and dectin-1. Nat Med 2012; 18: 1401-1406.
-
(2012)
Nat Med
, vol.18
, pp. 1401-1406
-
-
Karsten, C.M.1
Pandey, M.K.2
Figge, J.3
-
2
-
-
84861994937
-
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes
-
Naito AT, Sumida T, Nomura S et al. Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell 2012; 149: 1298-1313.
-
(2012)
Cell
, vol.149
, pp. 1298-1313
-
-
Naito, A.T.1
Sumida, T.2
Nomura, S.3
-
3
-
-
84855171565
-
Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis
-
Sargsyan SA, Serkova NJ, Renner B et al. Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis. Kidney Int 2012; 81: 152-159.
-
(2012)
Kidney Int
, vol.81
, pp. 152-159
-
-
Sargsyan, S.A.1
Serkova, N.J.2
Renner, B.3
-
4
-
-
55749090775
-
Pathology, clinical presentations, and outcomes of C1q nephropathy
-
Vizjak A, Ferluga D, Rozic M et al. Pathology, clinical presentations, and outcomes of C1q nephropathy. J Am Soc Nephrol 2008; 19: 2237-2244.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2237-2244
-
-
Vizjak, A.1
Ferluga, D.2
Rozic, M.3
-
5
-
-
68749118182
-
Current status and issues of C1q nephropathy
-
Mii A, Shimizu A, Masuda Y et al. Current status and issues of C1q nephropathy. Clin Exp Nephrol 2009; 13: 263-274.
-
(2009)
Clin Exp Nephrol
, vol.13
, pp. 263-274
-
-
Mii, A.1
Shimizu, A.2
Masuda, Y.3
-
6
-
-
84886614258
-
Immunopathology of membranoproliferative glomerulonephritis with subendothelial deposits (Type i MPGN)
-
Levy M, Gubler MC, Sich M et al. Immunopathology of membranoproliferative glomerulonephritis with subendothelial deposits (Type I MPGN). Clin Immunol Immunopathol 1978; 10: 477-492.
-
(1978)
Clin Immunol Immunopathol
, vol.10
, pp. 477-492
-
-
Levy, M.1
Gubler, M.C.2
Sich, M.3
-
7
-
-
0016733991
-
Dense deposit disease: A variant of membranoproliferative glomerulonephritis
-
Habib R, Gubler MC, Loirat C et al. Dense deposit disease: A variant of membranoproliferative glomerulonephritis. Kidney Int 1975; 7: 204-215.
-
(1975)
Kidney Int
, vol.7
, pp. 204-215
-
-
Habib, R.1
Gubler, M.C.2
Loirat, C.3
-
8
-
-
0017361295
-
Membranoproliferative glomerulonephritis with disruption of the glomerular basement membrane
-
Strife CF, McEnery PT, McAdams AJ et al. Membranoproliferative glomerulonephritis with disruption of the glomerular basement membrane. Clin Nephrol 1977; 7: 65-72.
-
(1977)
Clin Nephrol
, vol.7
, pp. 65-72
-
-
Strife, C.F.1
McEnery, P.T.2
McAdams, A.J.3
-
9
-
-
84857113842
-
Membranoproliferative glomerulonephritis and C3 glomerulopathy: Resolving the confusion
-
Sethi S, Nester CM, Smith RJ. Membranoproliferative glomerulonephritis and C3 glomerulopathy: Resolving the confusion. Kidney Int 2012; 81: 434-441.
-
(2012)
Kidney Int
, vol.81
, pp. 434-441
-
-
Sethi, S.1
Nester, C.M.2
Smith, R.J.3
-
11
-
-
34147180032
-
Primary glomerulonephritis with isolated C3 deposits: A new entity which shares common genetic risk factors with haemolytic uraemic syndrome
-
Servais A, Fremeaux-Bacchi V, Lequintrec M et al. Primary glomerulonephritis with isolated C3 deposits: A new entity which shares common genetic risk factors with haemolytic uraemic syndrome. J Med Genet 2007; 44: 193-199.
-
(2007)
J Med Genet
, vol.44
, pp. 193-199
-
-
Servais, A.1
Fremeaux-Bacchi, V.2
Lequintrec, M.3
-
12
-
-
77957827919
-
Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation
-
Martinez-Barricarte R, Heurich M, Valdes-Canedo F et al. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. J Clin Invest 2010; 120: 3702-3712.
-
(2010)
J Clin Invest
, vol.120
, pp. 3702-3712
-
-
Martinez-Barricarte, R.1
Heurich, M.2
Valdes-Canedo, F.3
-
13
-
-
64949093413
-
Glomeruli of dense deposit disease contain components of the alternative and terminal complement pathway
-
Sethi S, Gamez JD, Vrana JA et al. Glomeruli of dense deposit disease contain components of the alternative and terminal complement pathway. Kidney Int 2009; 75: 952-960.
-
(2009)
Kidney Int
, vol.75
, pp. 952-960
-
-
Sethi, S.1
Gamez, J.D.2
Vrana, J.A.3
-
14
-
-
79957858528
-
Proliferative glomerulonephritis secondary to dysfunction of the alternative pathway of complement
-
Sethi S, Fervenza FC, Zhang Y et al. Proliferative glomerulonephritis secondary to dysfunction of the alternative pathway of complement. Clin J Am Soc Nephrol 2011; 6: 1009-1017.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 1009-1017
-
-
Sethi, S.1
Fervenza, F.C.2
Zhang, Y.3
-
15
-
-
84863115476
-
Causes of alternative pathway dysregulation in dense deposit disease
-
Zhang Y, Meyer NC, Wang K et al. Causes of alternative pathway dysregulation in dense deposit disease. Clin J Am Soc Nephrol 2012; 7: 265-274.
-
(2012)
Clin J Am Soc Nephrol
, vol.7
, pp. 265-274
-
-
Zhang, Y.1
Meyer, N.C.2
Wang, K.3
-
16
-
-
84864564017
-
C3 glomerulonephritis: Clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up
-
Sethi S, Fervenza FC, Zhang Y et al. C3 glomerulonephritis: Clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up. Kidney Int 2012; 82: 465-473.
-
(2012)
Kidney Int
, vol.82
, pp. 465-473
-
-
Sethi, S.1
Fervenza, F.C.2
Zhang, Y.3
-
17
-
-
84864554927
-
Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
-
Servais A, Noel LH, Roumenina LT et al. Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int 2012; 82: 454-464.
-
(2012)
Kidney Int
, vol.82
, pp. 454-464
-
-
Servais, A.1
Noel, L.H.2
Roumenina, L.T.3
-
18
-
-
34249112293
-
Dense deposit disease is not a membranoproliferative glomerulonephritis
-
Walker PD, Ferrario F, Joh K et al. Dense deposit disease is not a membranoproliferative glomerulonephritis. Mod Pathol 2007; 20: 605-616.
-
(2007)
Mod Pathol
, vol.20
, pp. 605-616
-
-
Walker, P.D.1
Ferrario, F.2
Joh, K.3
-
19
-
-
64049119966
-
Dense deposit disease: Clinicopathologic study of 32 pediatric and adult patients
-
Nasr SH, Valeri AM, Appel GB et al. Dense deposit disease: Clinicopathologic study of 32 pediatric and adult patients. Clin J Am Soc Nephrol 2009; 4: 22-32.
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, pp. 22-32
-
-
Nasr, S.H.1
Valeri, A.M.2
Appel, G.B.3
-
20
-
-
33745716919
-
Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease)
-
Abrera-Abeleda MA, Nishimura C, Smith JL et al. Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease). J Med Genet 2006; 43: 582-589.
-
(2006)
J Med Genet
, vol.43
, pp. 582-589
-
-
Abrera-Abeleda, M.A.1
Nishimura, C.2
Smith, J.L.3
-
21
-
-
84868585648
-
Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation
-
Paixao-Cavalcante D, Lopez-Trascasa M, Skattum L et al. Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation. Kidney Int 2012; 82: 1084-1092.
-
(2012)
Kidney Int
, vol.82
, pp. 1084-1092
-
-
Paixao-Cavalcante, D.1
Lopez-Trascasa, M.2
Skattum, L.3
-
22
-
-
79961214569
-
Membranoproliferative glomerulonephritis: Pathogenetic heterogeneity and proposal for a new classification
-
Sethi S, Fervenza FC. Membranoproliferative glomerulonephritis: Pathogenetic heterogeneity and proposal for a new classification. Semin Nephrol 2011; 31: 341-348.
-
(2011)
Semin Nephrol
, vol.31
, pp. 341-348
-
-
Sethi, S.1
Fervenza, F.C.2
-
23
-
-
77956394517
-
Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis
-
Gale DP, de Jorge EG, Cook HT et al. Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis. Lancet 2010; 376: 794-801.
-
(2010)
Lancet
, vol.376
, pp. 794-801
-
-
Gale, D.P.1
De Jorge, E.G.2
Cook, H.T.3
-
24
-
-
79958192481
-
Familial C3 glomerulopathy associated with CFHR5 mutations: Clinical characteristics of 91 patients in 16 pedigrees
-
Athanasiou Y, Voskarides K, Gale DP et al. Familial C3 glomerulopathy associated with CFHR5 mutations: Clinical characteristics of 91 patients in 16 pedigrees. Clin J Am Soc Nephrol 2011; 6: 1436-1446.
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 1436-1446
-
-
Athanasiou, Y.1
Voskarides, K.2
Gale, D.P.3
-
26
-
-
84867994785
-
Pathogenesis of the C3 glomerulopathies and reclassification of MPGN
-
Bomback AS, Appel GB. Pathogenesis of the C3 glomerulopathies and reclassification of MPGN. Nat Rev Nephrol 2012; 8: 634-642.
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 634-642
-
-
Bomback, A.S.1
Appel, G.B.2
-
27
-
-
84860779074
-
Eculizumab for dense deposit disease and C3 glomerulonephritis
-
Bomback AS, Smith RJ, Barile GR et al. Eculizumab for dense deposit disease and C3 glomerulonephritis. Clin J Am Soc Nephrol 2012; 7: 748-756.
-
(2012)
Clin J Am Soc Nephrol
, vol.7
, pp. 748-756
-
-
Bomback, A.S.1
Smith, R.J.2
Barile, G.R.3
-
28
-
-
84858633062
-
Eculizumab and refractory membranoproliferative glomerulonephritis
-
Radhakrishnan S, Lunn A, Kirschfink M et al. Eculizumab and refractory membranoproliferative glomerulonephritis. N Engl J Med 2012; 366: 1165-1166.
-
(2012)
N Engl J Med
, vol.366
, pp. 1165-1166
-
-
Radhakrishnan, S.1
Lunn, A.2
Kirschfink, M.3
-
29
-
-
84858661698
-
Eculizumab for the treatment of densedeposit disease
-
Vivarelli M, Pasini A, Emma F. Eculizumab for the treatment of densedeposit disease. N Engl J Med 2012; 366: 1163-1165.
-
(2012)
N Engl J Med
, vol.366
, pp. 1163-1165
-
-
Vivarelli, M.1
Pasini, A.2
Emma, F.3
-
30
-
-
84858671433
-
Eculizumab in a patient with dense-deposit disease
-
Daina E, Noris M, Remuzzi G. Eculizumab in a patient with dense-deposit disease. N Engl J Med 2012; 366: 1161-1163.
-
(2012)
N Engl J Med
, vol.366
, pp. 1161-1163
-
-
Daina, E.1
Noris, M.2
Remuzzi, G.3
-
31
-
-
84859421387
-
Recurrent dense deposit disease after renal transplantation: An emerging role for complementary therapies
-
McCaughan JA, O'Rourke DM, Courtney AE. Recurrent dense deposit disease after renal transplantation: An emerging role for complementary therapies. Am J Transplant 2012; 12: 1046-1051.
-
(2012)
Am J Transplant
, vol.12
, pp. 1046-1051
-
-
McCaughan, J.A.1
O'rourke, D.M.2
Courtney, A.E.3
-
32
-
-
0022846898
-
Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat
-
Bagchus WM, Hoedemaeker PJ, Rozing J et al. Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat. Lab Invest 1986; 55: 680-687.
-
(1986)
Lab Invest
, vol.55
, pp. 680-687
-
-
Bagchus, W.M.1
Hoedemaeker, P.J.2
Rozing, J.3
-
33
-
-
84860848481
-
Sublytic C5b-9 complexes induce apoptosis of glomerular mesangial cells in rats with Thy-1 nephritis through role of interferon regulatory factor-1-dependent caspase 8 activation
-
Liu L, Qiu W, Wang H et al. Sublytic C5b-9 complexes induce apoptosis of glomerular mesangial cells in rats with Thy-1 nephritis through role of interferon regulatory factor-1-dependent caspase 8 activation. J Biol Chem 2012; 287: 16410-16423.
-
(2012)
J Biol Chem
, vol.287
, pp. 16410-16423
-
-
Liu, L.1
Qiu, W.2
Wang, H.3
-
34
-
-
0028147981
-
Glycosylation of IgA is required for optimal activation of the alternative complement pathway by immune complexes
-
Zhang W, Lachmann PJ. Glycosylation of IgA is required for optimal activation of the alternative complement pathway by immune complexes. Immunology 1994; 81: 137-141.
-
(1994)
Immunology
, vol.81
, pp. 137-141
-
-
Zhang, W.1
Lachmann, P.J.2
-
35
-
-
80053534268
-
The pathophysiology of IgA nephropathy
-
Suzuki H, Kiryluk K, Novak J et al. The pathophysiology of IgA nephropathy. J Am Soc Nephrol 2011; 22: 1795-1803.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1795-1803
-
-
Suzuki, H.1
Kiryluk, K.2
Novak, J.3
-
36
-
-
38349134274
-
The role of secretory IgA and complement in IgA nephropathy
-
Oortwijn BD, Eijgenraam JW, Rastaldi MP et al. The role of secretory IgA and complement in IgA nephropathy. Semin Nephrol 2008; 28: 58-65.
-
(2008)
Semin Nephrol
, vol.28
, pp. 58-65
-
-
Oortwijn, B.D.1
Eijgenraam, J.W.2
Rastaldi, M.P.3
-
37
-
-
79953224410
-
Genome-wide association study identifies susceptibility loci for IgA nephropathy
-
Gharavi AG, Kiryluk K, Choi M et al. Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet 2011; 43: 321-327.
-
(2011)
Nat Genet
, vol.43
, pp. 321-327
-
-
Gharavi, A.G.1
Kiryluk, K.2
Choi, M.3
-
38
-
-
51649113133
-
C5b-9 glomerular deposition and tubular alpha3beta1-integrin expression are implicated in the development of chronic lesions and predict renal function outcome in immunoglobulin A nephropathy
-
Stangou M, Alexopoulos E, Pantzaki A et al. C5b-9 glomerular deposition and tubular alpha3beta1-integrin expression are implicated in the development of chronic lesions and predict renal function outcome in immunoglobulin A nephropathy. Scand J Urol Nephrol 2008; 42: 373-380.
-
(2008)
Scand J Urol Nephrol
, vol.42
, pp. 373-380
-
-
Stangou, M.1
Alexopoulos, E.2
Pantzaki, A.3
-
39
-
-
60749132251
-
Mesangial C4d deposition: A new prognostic factor in IgA nephropathy
-
Espinosa M, Ortega R, Gomez-Carrasco JM et al. Mesangial C4d deposition: A new prognostic factor in IgA nephropathy. Nephrol Dial Transplant 2009; 24: 886-891.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 886-891
-
-
Espinosa, M.1
Ortega, R.2
Gomez-Carrasco, J.M.3
-
40
-
-
33646924264
-
Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease
-
Roos A, Rastaldi MP, Calvaresi N et al. Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol 2006; 17: 1724-1734.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1724-1734
-
-
Roos, A.1
Rastaldi, M.P.2
Calvaresi, N.3
-
41
-
-
4744376173
-
Pathomechanisms and molecular basis of membranous glomerulopathy
-
Kerjaschki D. Pathomechanisms and molecular basis of membranous glomerulopathy. Lancet 2004; 364: 1194-1196.
-
(2004)
Lancet
, vol.364
, pp. 1194-1196
-
-
Kerjaschki, D.1
-
42
-
-
23944438985
-
Cellular response to injury in membranous nephropathy
-
Nangaku M, Shankland SJ, Couser WG. Cellular response to injury in membranous nephropathy. J Am Soc Nephrol 2005; 16: 1195-1204.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1195-1204
-
-
Nangaku, M.1
Shankland, S.J.2
Couser, W.G.3
-
43
-
-
79551503342
-
Membranous nephropathy
-
Cybulsky AV. Membranous nephropathy. Contrib Nephrol 2011; 169: 107-125.
-
(2011)
Contrib Nephrol
, vol.169
, pp. 107-125
-
-
Cybulsky, A.V.1
-
44
-
-
67649658244
-
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy
-
Beck LH Jr, Bonegio RG, Lambeau G et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009; 361: 11-21.
-
(2009)
N Engl J Med
, vol.361
, pp. 11-21
-
-
Beck Jr., L.H.1
Bonegio, R.G.2
Lambeau, G.3
-
45
-
-
0037152082
-
Rituximab for idiopathic membranous nephropathy
-
Remuzzi G, Chiurchiu C, Abbate M et al. Rituximab for idiopathic membranous nephropathy. Lancet 2002; 360: 923-924.
-
(2002)
Lancet
, vol.360
, pp. 923-924
-
-
Remuzzi, G.1
Chiurchiu, C.2
Abbate, M.3
-
46
-
-
84864833114
-
Rituximab in idiopathic membranous nephropathy
-
Ruggenenti P, Cravedi P, Chianca A et al. Rituximab in idiopathic membranous nephropathy. J Am Soc Nephrol 2012; 23: 1416-1425.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1416-1425
-
-
Ruggenenti, P.1
Cravedi, P.2
Chianca, A.3
-
47
-
-
37248999499
-
Rituximab treatment of idiopathic membranous nephropathy
-
Fervenza FC, Cosio FG, Erickson SB et al. Rituximab treatment of idiopathic membranous nephropathy. Kidney Int 2008; 73: 117-125.
-
(2008)
Kidney Int
, vol.73
, pp. 117-125
-
-
Fervenza, F.C.1
Cosio, F.G.2
Erickson, S.B.3
-
48
-
-
0016403925
-
Letter: Haemolytic-uraemic syndrome: Evidence for intravascular C3 activation
-
Stuhlinger W, Kourilsky O, Kanfer A et al. Letter: Haemolytic-uraemic syndrome: Evidence for intravascular C3 activation. Lancet 1974; 2: 788-789.
-
(1974)
Lancet
, vol.2
, pp. 788-789
-
-
Stuhlinger, W.1
Kourilsky, O.2
Kanfer, A.3
-
49
-
-
0031970553
-
Genetic studies into inherited and sporadic hemolytic uremic syndrome
-
Warwicker P, Goodship TH, Donne RL et al. Genetic studies into inherited and sporadic hemolytic uremic syndrome. Kidney Int 1998; 53: 836-844.
-
(1998)
Kidney Int
, vol.53
, pp. 836-844
-
-
Warwicker, P.1
Goodship, T.H.2
Donne, R.L.3
-
50
-
-
70350279315
-
Atypical hemolytic-uremic syndrome
-
Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med 2009; 361: 1676-1687.
-
(2009)
N Engl J Med
, vol.361
, pp. 1676-1687
-
-
Noris, M.1
Remuzzi, G.2
-
51
-
-
67449119124
-
The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome
-
Ferreira VP, Herbert AP, Cortes C et al. The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome. J Immunol 2009; 182: 7009-7018.
-
(2009)
J Immunol
, vol.182
, pp. 7009-7018
-
-
Ferreira, V.P.1
Herbert, A.P.2
Cortes, C.3
-
52
-
-
33745812440
-
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome
-
Fremeaux-Bacchi V, Moulton EA, Kavanagh D et al. Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. J Am Soc Nephrol 2006; 17: 2017-2025.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2017-2025
-
-
Fremeaux-Bacchi, V.1
Moulton, E.A.2
Kavanagh, D.3
-
53
-
-
33746655453
-
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome
-
Heinen S, Sanchez-Corral P, Jackson MS et al. De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome. Hum Mutat 2006; 27: 292-293.
-
(2006)
Hum Mutat
, vol.27
, pp. 292-293
-
-
Heinen, S.1
Sanchez-Corral, P.2
Jackson, M.S.3
-
54
-
-
62449341861
-
Autoantibodies in haemolytic uraemic syndrome (HUS)
-
Skerka C, Jozsi M, Zipfel PF et al. Autoantibodies in haemolytic uraemic syndrome (HUS). Thromb Haemost 2009; 101: 227-232.
-
(2009)
Thromb Haemost
, vol.101
, pp. 227-232
-
-
Skerka, C.1
Jozsi, M.2
Zipfel, P.F.3
-
55
-
-
78649863686
-
Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome
-
Dragon-Durey MA, Sethi SK, Bagga A et al. Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome. J Am Soc Nephrol 2010; 21: 2180-2187.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 2180-2187
-
-
Dragon-Durey, M.A.1
Sethi, S.K.2
Bagga, A.3
-
56
-
-
73649122762
-
Alternative pathway of complement in children with diarrhea-associated hemolytic uremic syndrome
-
Thurman JM, Marians R, Emlen W et al. Alternative pathway of complement in children with diarrhea-associated hemolytic uremic syndrome. Clin J Am Soc Nephrol 2009; 4: 1920-1924.
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, pp. 1920-1924
-
-
Thurman, J.M.1
Marians, R.2
Emlen, W.3
-
57
-
-
79960435714
-
Alternative pathway activation of complement by Shiga toxin promotes exuberant C3a formation that triggers microvascular thrombosis
-
Morigi M, Galbusera M, Gastoldi S et al. Alternative pathway activation of complement by Shiga toxin promotes exuberant C3a formation that triggers microvascular thrombosis. J Immunol 2011; 187: 172-180.
-
(2011)
J Immunol
, vol.187
, pp. 172-180
-
-
Morigi, M.1
Galbusera, M.2
Gastoldi, S.3
-
58
-
-
84866544002
-
Lack of the lectin-like domain of thrombomodulin worsens shiga toxin-associated hemolytic uremic syndrome in Mice
-
Zoja C, Locatelli M, Pagani C et al. Lack of the Lectin-like Domain of Thrombomodulin Worsens Shiga Toxin-Associated Hemolytic Uremic Syndrome in Mice. J Immunol 2012; 189: 3661-3668.
-
(2012)
J Immunol
, vol.189
, pp. 3661-3668
-
-
Zoja, C.1
Locatelli, M.2
Pagani, C.3
-
59
-
-
84860474599
-
Complement activation in thrombotic thrombocytopenic purpura
-
Reti M, Farkas P, Csuka D et al. Complement activation in thrombotic thrombocytopenic purpura. J Thromb Haemost 2012; 10: 791-798.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 791-798
-
-
Reti, M.1
Farkas, P.2
Csuka, D.3
-
60
-
-
33747159590
-
Genetics of HUS: The impact of MCP, CFH, and if mutations on clinical presentation, response to treatment, and outcome
-
Caprioli J, Noris M, Brioschi S et al. Genetics of HUS: The impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. Blood 2006; 108: 1267-1279.
-
(2006)
Blood
, vol.108
, pp. 1267-1279
-
-
Caprioli, J.1
Noris, M.2
Brioschi, S.3
-
61
-
-
33846094404
-
Gain-offunction mutations in complement factor B are associated with atypical hemolytic uremic syndrome
-
Goicoechea De Jorge E, Harris CL, Esparza-Gordillo J et al. Gain-offunction mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proc Natl Acad Sci USA 2007; 104: 240-245.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 240-245
-
-
Goicoechea De Jorge, E.1
Harris, C.L.2
Esparza-Gordillo, J.3
-
62
-
-
54049137505
-
Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome
-
Fremeaux-Bacchi V, Miller EC, Liszewski MK et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. Blood 2008; 112: 4948-4952.
-
(2008)
Blood
, vol.112
, pp. 4948-4952
-
-
Fremeaux-Bacchi, V.1
Miller, E.C.2
Liszewski, M.K.3
-
63
-
-
84867993256
-
Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
-
Zuber J, Fakhouri F, Roumenina LT et al. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol 2012; 8: 643-657.
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 643-657
-
-
Zuber, J.1
Fakhouri, F.2
Roumenina, L.T.3
-
64
-
-
75749119748
-
Excessive activation of the complement system in atypical hemolytic uremic syndrome: Is it ready for prime time?
-
Tsai HM. Excessive activation of the complement system in atypical hemolytic uremic syndrome: Is it ready for prime time? Kidney Int 2010; 77: 267-269.
-
(2010)
Kidney Int
, vol.77
, pp. 267-269
-
-
Tsai, H.M.1
-
65
-
-
84861510183
-
Therapeutic regulation of complement in patients with renal disease - Where is the promise?
-
Thurman JM. Therapeutic regulation of complement in patients with renal disease - where is the promise? Clin Nephrol 2012; 77: 413-423.
-
(2012)
Clin Nephrol
, vol.77
, pp. 413-423
-
-
Thurman, J.M.1
-
67
-
-
84861526957
-
Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura.
-
Chapin J, Weksler B, Magro C et al. Eculizumab in the treatment of refractory idiopathic thrombotic thrombocytopenic purpura. Br J Haematol 2012; 157: 772-774.
-
(2012)
Br J Haematol
, vol.157
, pp. 772-774
-
-
Chapin, J.1
Weksler, B.2
Magro, C.3
-
68
-
-
4644304889
-
Glycation inactivation of the complement regulatory protein CD59: A possible role in the pathogenesis of the vascular complications of human diabetes
-
Qin X, Goldfine A, Krumrei N et al. Glycation inactivation of the complement regulatory protein CD59: A possible role in the pathogenesis of the vascular complications of human diabetes. Diabetes 2004; 53: 2653-2661.
-
(2004)
Diabetes
, vol.53
, pp. 2653-2661
-
-
Qin, X.1
Goldfine, A.2
Krumrei, N.3
-
69
-
-
3242709799
-
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: Glycoxidationmediated local complement activation
-
Uesugi N, Sakata N, Nangaku M et al. Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: Glycoxidationmediated local complement activation. Am J Kidney Dis 2004; 44: 224-238.
-
(2004)
Am J Kidney Dis
, vol.44
, pp. 224-238
-
-
Uesugi, N.1
Sakata, N.2
Nangaku, M.3
-
70
-
-
77955657700
-
Association between mannose-binding lectin, high-sensitivity C-reactive protein and the progression of diabetic nephropathy in type 1 diabetes
-
Hansen TK, Forsblom C, Saraheimo M et al. Association between mannose-binding lectin, high-sensitivity C-reactive protein and the progression of diabetic nephropathy in type 1 diabetes. Diabetologia 2010; 53: 1517-1524.
-
(2010)
Diabetologia
, vol.53
, pp. 1517-1524
-
-
Hansen, T.K.1
Forsblom, C.2
Saraheimo, M.3
-
71
-
-
80052875303
-
Transcriptome analysis of human diabetic kidney disease
-
Woroniecka KI, Park AS, Mohtat D et al. Transcriptome analysis of human diabetic kidney disease. Diabetes 2011; 60: 2354-2369.
-
(2011)
Diabetes
, vol.60
, pp. 2354-2369
-
-
Woroniecka, K.I.1
Park, A.S.2
Mohtat, D.3
-
72
-
-
84863303697
-
The association of genetic variants of type 2 diabetes with kidney function
-
Franceschini N, Shara NM, Wang H et al. The association of genetic variants of type 2 diabetes with kidney function. Kidney Int 2012; 82: 220-225.
-
(2012)
Kidney Int
, vol.82
, pp. 220-225
-
-
Franceschini, N.1
Shara, N.M.2
Wang, H.3
-
73
-
-
84866889255
-
New susceptibility loci associated with kidney disease in type 1 diabetes
-
Sandholm N, Salem RM, McKnight AJ et al. New susceptibility loci associated with kidney disease in type 1 diabetes. PLoS Genet 2012; 8: E1002921.
-
(2012)
PLoS Genet
, vol.8
-
-
Sandholm, N.1
Salem, R.M.2
McKnight, A.J.3
-
74
-
-
84878783069
-
Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes
-
Alkayyali S, Lajer M, Deshmukh H et al. Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes. Diabetologia 2013; 56: 323-329.
-
(2013)
Diabetologia
, vol.56
, pp. 323-329
-
-
Alkayyali, S.1
Lajer, M.2
Deshmukh, H.3
-
75
-
-
84871422480
-
The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition
-
Wang H, Vinnikov I, Shahzad K et al. The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition. Thromb Haemost 2012; 108: 1141-1153.
-
(2012)
Thromb Haemost
, vol.108
, pp. 1141-1153
-
-
Wang, H.1
Vinnikov, I.2
Shahzad, K.3
-
76
-
-
33847052568
-
Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies
-
Xiao H, Schreiber A, Heeringa P et al. Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies. Am J Pathol 2007; 170: 52-64.
-
(2007)
Am J Pathol
, vol.170
, pp. 52-64
-
-
Xiao, H.1
Schreiber, A.2
Heeringa, P.3
-
77
-
-
33947651247
-
Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice
-
Huugen D, van Esch A, Xiao H et al. Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice. Kidney Int 2007; 71: 646-654.
-
(2007)
Kidney Int
, vol.71
, pp. 646-654
-
-
Huugen, D.1
Van Esch, A.2
Xiao, H.3
-
78
-
-
67349223570
-
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis
-
Xing GQ, Chen M, Liu G et al. Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol 2009; 29: 282-291.
-
(2009)
J Clin Immunol
, vol.29
, pp. 282-291
-
-
Xing, G.Q.1
Chen, M.2
Liu, G.3
-
79
-
-
84871785269
-
Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
-
Gou SJ, Yuan J, Chen M et al. Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis. Kidney Int 2013; 83: 129-137.
-
(2013)
Kidney Int
, vol.83
, pp. 129-137
-
-
Gou, S.J.1
Yuan, J.2
Chen, M.3
-
80
-
-
84864014453
-
Genetically distinct subsets within ANCA-associated vasculitis
-
Lyons PA, Rayner TF, Trivedi S et al. Genetically distinct subsets within ANCA-associated vasculitis. N Engl J Med 2012; 367: 214-223.
-
(2012)
N Engl J Med
, vol.367
, pp. 214-223
-
-
Lyons, P.A.1
Rayner, T.F.2
Trivedi, S.3
-
81
-
-
0031726578
-
Proteinuria and damage to tubular cells-is complement a culprit?
-
Matsuo S, Morita Y, Mizuno M et al. Proteinuria and damage to tubular cells-is complement a culprit? Nephrol Dial Transplant 1998; 13: 2723-2726.
-
(1998)
Nephrol Dial Transplant
, vol.13
, pp. 2723-2726
-
-
Matsuo, S.1
Morita, Y.2
Mizuno, M.3
-
82
-
-
0032979345
-
Chronic interstitial damage in proteinuria. Does complement mediate tubulointerstitial injury?
-
Sheerin NS, Sacks SH. Chronic interstitial damage in proteinuria. Does complement mediate tubulointerstitial injury? Kidney Blood Press Res 1999; 22: 47-52.
-
(1999)
Kidney Blood Press Res
, vol.22
, pp. 47-52
-
-
Sheerin, N.S.1
Sacks, S.H.2
-
84
-
-
77950233806
-
Urinary properdin excretion is associated with intrarenal complement activation and poor renal function
-
Siezenga MA, van der Geest RN, Mallat MJ et al. Urinary properdin excretion is associated with intrarenal complement activation and poor renal function. Nephrol Dial Transplant 2010; 25: 1157-1161.
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 1157-1161
-
-
Siezenga, M.A.1
Van Der Geest, R.N.2
Mallat, M.J.3
-
85
-
-
79953128389
-
Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease
-
Zaferani A, Vives RR, van der Pol P et al. Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease. J Biol Chem 2011; 286: 5359-5367.
-
(2011)
J Biol Chem
, vol.286
, pp. 5359-5367
-
-
Zaferani, A.1
Vives, R.R.2
Van Der Pol, P.3
-
86
-
-
77952477767
-
The role of tubulointerstitial inflammation in the progression of chronic renal failure
-
Rodriguez-Iturbe B, Garcia Garcia G. The role of tubulointerstitial inflammation in the progression of chronic renal failure. Nephron Clin Pract 2010; 116: C81-c88.
-
(2010)
Nephron Clin Pract
, vol.116
-
-
Rodriguez-Iturbe, B.1
Garcia Garcia, G.2
-
87
-
-
84863010724
-
Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury
-
Bao L, Wang Y, Haas M et al. Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury. Kidney Int 2011; 80: 524-534.
-
(2011)
Kidney Int
, vol.80
, pp. 524-534
-
-
Bao, L.1
Wang, Y.2
Haas, M.3
-
88
-
-
78049388842
-
The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells
-
Renner B, Coleman K, Goldberg R et al. The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells. J Immunol 2010; 185: 3086-3094.
-
(2010)
J Immunol
, vol.185
, pp. 3086-3094
-
-
Renner, B.1
Coleman, K.2
Goldberg, R.3
-
89
-
-
33947256458
-
Unrestricted C3 activation occurs in Crrydeficient kidneys and rapidly leads to chronic renal failure
-
Bao L, Wang Y, Chang A et al. Unrestricted C3 activation occurs in Crrydeficient kidneys and rapidly leads to chronic renal failure. J Am Soc Nephrol 2007; 18: 811-822.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 811-822
-
-
Bao, L.1
Wang, Y.2
Chang, A.3
-
90
-
-
3042692326
-
Blockade of CCR2 ameliorates progressive fibrosis in kidney
-
Kitagawa K, Wada T, Furuichi K et al. Blockade of CCR2 ameliorates progressive fibrosis in kidney. Am J Pathol 2004; 165: 237-246.
-
(2004)
Am J Pathol
, vol.165
, pp. 237-246
-
-
Kitagawa, K.1
Wada, T.2
Furuichi, K.3
-
91
-
-
0034082750
-
Predominant role for C5b-9 in renal ischemia/reperfusion injury
-
Zhou W, Farrar CA, Abe K et al. Predominant role for C5b-9 in renal ischemia/reperfusion injury. J Clin Invest 2000; 105: 1363-1371.
-
(2000)
J Clin Invest
, vol.105
, pp. 1363-1371
-
-
Zhou, W.1
Farrar, C.A.2
Abe, K.3
-
92
-
-
32444446595
-
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion
-
Thurman JM, Ljubanovic D, Royer PA et al. Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion. J Clin Invest 2006; 116: 357-368.
-
(2006)
J Clin Invest
, vol.116
, pp. 357-368
-
-
Thurman, J.M.1
Ljubanovic, D.2
Royer, P.A.3
-
93
-
-
1542619241
-
Critical protection from renal ischemia reperfusion injury by CD55 and CD59
-
Yamada K, Miwa T, Liu J et al. Critical protection from renal ischemia reperfusion injury by CD55 and CD59. J Immunol 2004; 172: 3869-3875.
-
(2004)
J Immunol
, vol.172
, pp. 3869-3875
-
-
Yamada, K.1
Miwa, T.2
Liu, J.3
-
94
-
-
4344632212
-
CD59a deficiency exacerbates ischemia-reperfusion injury in mice
-
Turnberg D, Botto M, Lewis M et al. CD59a deficiency exacerbates ischemia-reperfusion injury in mice. Am J Pathol 2004; 165: 825-832.
-
(2004)
Am J Pathol
, vol.165
, pp. 825-832
-
-
Turnberg, D.1
Botto, M.2
Lewis, M.3
-
95
-
-
0028702973
-
Complement activation by the hydroxyl radical during intestinal reperfusion
-
Turnage RH, Magee JC, Guice KS et al. Complement activation by the hydroxyl radical during intestinal reperfusion. Shock 1994; 2: 445-450.
-
(1994)
Shock
, vol.2
, pp. 445-450
-
-
Turnage, R.H.1
Magee, J.C.2
Guice, K.S.3
-
96
-
-
79959785187
-
Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury
-
Renner B, Ferreira VP, Cortes C et al. Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury. Kidney Int 2011; 80: 165-173.
-
(2011)
Kidney Int
, vol.80
, pp. 165-173
-
-
Renner, B.1
Ferreira, V.P.2
Cortes, C.3
-
97
-
-
84865978985
-
C3a and c5a promote renal ischemiareperfusion injury
-
Peng Q, Li K, Smyth LA et al. C3a and c5a promote renal ischemiareperfusion injury. J Am Soc Nephrol 2012; 23: 1474-1485.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1474-1485
-
-
Peng, Q.1
Li, K.2
Smyth, L.A.3
-
98
-
-
84867997580
-
STEC-HUS, atypical HUS and TTP are all diseases of complement activation
-
Noris M, Mescia F, Remuzzi G. STEC-HUS, atypical HUS and TTP are all diseases of complement activation. Nat Rev Nephrol 2012; 8: 622-633.
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 622-633
-
-
Noris, M.1
Mescia, F.2
Remuzzi, G.3
|