메뉴 건너뛰기




Volumn 80, Issue 5, 2011, Pages 524-534

Distinct roles for C3a and C5a in complement-induced tubulointerstitial injury

Author keywords

Complement; Interstitial fibrosis; Renal failure; Transgenic mouse; Transplantation

Indexed keywords

CD11B ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C3A RECEPTOR; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT RECEPTOR; F4 80 ANTIGEN; THY 1 ANTIGEN; THY 1.2 ANTIGEN; UNCLASSIFIED DRUG; COMPLEMENT; COMPLEMENT COMPONENT C5;

EID: 84863010724     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.158     Document Type: Article
Times cited : (41)

References (55)
  • 1
    • 0035810399 scopus 로고    scopus 로고
    • Advances in immunology: Complement (first of two parts)
    • DOI 10.1056/NEJM200104053441406
    • Walport MJ. Advances in immunology: complement (first of two parts). N Engl J Med 2001; 344: 1058-1066. (Pubitemid 32267977)
    • (2001) New England Journal of Medicine , vol.344 , Issue.14 , pp. 1058-1066
    • Walport, M.J.1
  • 2
    • 0028954469 scopus 로고
    • Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein
    • Kim Y-U, Kinoshita T, Molina H et al. Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J Exp Med 1995; 181: 151-159.
    • (1995) J Exp Med , vol.181 , pp. 151-159
    • Kim, Y.-U.1    Kinoshita, T.2    Molina, H.3
  • 3
    • 0034695647 scopus 로고    scopus 로고
    • A critical role for murine complement regulator Crry in fetomaternal tolerance
    • Xu C, Mao D, Holers VM et al. A critical role for murine complement regulator Crry in fetomaternal tolerance. Science 2000; 287: 498-501.
    • (2000) Science , vol.287 , pp. 498-501
    • Xu, C.1    Mao, D.2    Holers, V.M.3
  • 5
    • 78049388842 scopus 로고    scopus 로고
    • The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells
    • Renner B, Coleman K, Goldberg R et al. The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells. J Immunol 2010; 185: 3086-3094.
    • (2010) J Immunol , vol.185 , pp. 3086-3094
    • Renner, B.1    Coleman, K.2    Goldberg, R.3
  • 6
    • 0014421532 scopus 로고
    • Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
    • Risdon RA, Sloper JC, De Wardener HE. Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 1968; 2: 363-366.
    • (1968) Lancet , vol.2 , pp. 363-366
    • Risdon, R.A.1    Sloper, J.C.2    De Wardener, H.E.3
  • 7
    • 0026769228 scopus 로고
    • Tubulointerstitial changes as a major determinant in the progression of renal damage
    • Nath KA. Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kid Dis 1992; 20: 1-17.
    • (1992) Am J Kid Dis , vol.20 , pp. 1-17
    • Nath, K.A.1
  • 8
    • 68049129555 scopus 로고    scopus 로고
    • The role of the anaphylatoxins in health and disease
    • Klos A, Tenner AJ, Johswich KO et al. The role of the anaphylatoxins in health and disease. Mol Immunol 2009; 46: 2753-2766.
    • (2009) Mol Immunol , vol.46 , pp. 2753-2766
    • Klos, A.1    Tenner, A.J.2    Johswich, K.O.3
  • 11
    • 0026604784 scopus 로고
    • Binding of fluorescein-labeled anaphylatoxin C5a to human peripheral blood, spleen, and bone marrow leukocytes
    • Werfel T, Oppermann M, Schulze M et al. Binding of fluorescein-labeled anaphylatoxin C5a to human peripheral blood, spleen, and bone marrow leukocytes. Blood 1992; 79: 152-160.
    • (1992) Blood , vol.79 , pp. 152-160
    • Werfel, T.1    Oppermann, M.2    Schulze, M.3
  • 12
    • 0033120587 scopus 로고    scopus 로고
    • Human T cells express the C5a receptor and are chemoattracted to C5a
    • Nataf S, Davoust N, Ames RS et al. Human T cells express the C5a receptor and are chemoattracted to C5a. J Immunol 1999; 162: 4018-4023. (Pubitemid 29314783)
    • (1999) Journal of Immunology , vol.162 , Issue.7 , pp. 4018-4023
    • Nataf, S.1    Davoust, N.2    Ames, R.S.3    Barnum, S.R.4
  • 13
    • 0034541183 scopus 로고    scopus 로고
    • Activated human T lymphocytes express a functional C3a receptor
    • Werfel T, Kirchhoff K, Wittmann M et al. Activated human T lymphocytes express a functional C3a receptor. J Immunol 2000; 165: 6599-6605.
    • (2000) J Immunol , vol.165 , pp. 6599-6605
    • Werfel, T.1    Kirchhoff, K.2    Wittmann, M.3
  • 14
    • 0029000948 scopus 로고
    • C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a stimulation of neutrophils is secondary to eosinophil activation
    • Daffern PJ, Pfeifer PH, Ember JA et al. C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a stimulation of neutrophils is secondary to eosinophil activation. J Exp Med 1995; 181: 2119-2127.
    • (1995) J Exp Med , vol.181 , pp. 2119-2127
    • Daffern, P.J.1    Pfeifer, P.H.2    Ember, J.A.3
  • 15
    • 0033556365 scopus 로고    scopus 로고
    • A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo
    • DiScipio RG, Daffern PJ, Jagels MA et al. A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo. J Immunol 1999; 162: 1127-1136. (Pubitemid 29035444)
    • (1999) Journal of Immunology , vol.162 , Issue.2 , pp. 1127-1136
    • DiScipio, R.G.1    Daffern, P.J.2    Jagels, M.A.3    Broide, D.H.4    Sriramarao, P.5
  • 17
    • 0021952732 scopus 로고
    • Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg
    • Marder SR, Chenoweth DE, Goldstein IM et al. Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg. J Immunol 1985; 134: 3325-3331. (Pubitemid 15246474)
    • (1985) Journal of Immunology , vol.134 , Issue.5 , pp. 3325-3331
    • Marder, S.R.1    Chenoweth, D.E.2    Goldstein, I.M.3    Perez, H.D.4
  • 19
    • 0037111427 scopus 로고    scopus 로고
    • Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy
    • Drouin SM, Corry DB, Hollman TJ et al. Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. J Immunol 2002; 169: 5926-5933. (Pubitemid 35291699)
    • (2002) Journal of Immunology , vol.169 , Issue.10 , pp. 5926-5933
    • Drouin, S.M.1    Corry, D.B.2    Hollman, T.J.3    Kildsgaard, J.4    Wetsel, R.A.5
  • 20
    • 40249116606 scopus 로고    scopus 로고
    • Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells
    • Strainic MG, Liu J, Huang D et al. Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity 2008; 28: 425-435.
    • (2008) Immunity , vol.28 , pp. 425-435
    • Strainic, M.G.1    Liu, J.2    Huang, D.3
  • 21
    • 77954681931 scopus 로고    scopus 로고
    • The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B
    • Rosas M, Thomas B, Stacey M et al. The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J Leukoc Biol 2010; 88: 169-180.
    • (2010) J Leukoc Biol , vol.88 , pp. 169-180
    • Rosas, M.1    Thomas, B.2    Stacey, M.3
  • 22
    • 0030590652 scopus 로고    scopus 로고
    • Flow cytometric identification of murine neutrophils and monocytes
    • DOI 10.1016/0022-1759(96)00138-X
    • Lagasse E, Weissman IL. Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods 1996; 197: 139-150. (Pubitemid 26342018)
    • (1996) Journal of Immunological Methods , vol.197 , Issue.1-2 , pp. 139-150
    • Lagasse, E.1    Weissman, I.L.2
  • 24
    • 0041975937 scopus 로고    scopus 로고
    • Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo
    • DOI 10.1002/eji.200324003
    • Taylor PR, Brown GD, Geldhof AB et al. Pattern recognition receptors and differentiation antigens define murine myeloid cell heterogeneity ex vivo. Eur J Immunol 2003; 33: 2090-2097. (Pubitemid 37010025)
    • (2003) European Journal of Immunology , vol.33 , Issue.8 , pp. 2090-2097
    • Taylor, P.R.1    Brown, G.D.2    Geldhof, A.B.3    Martinez-Pomares, L.4    Gordon, S.5
  • 25
    • 58249116545 scopus 로고    scopus 로고
    • Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout
    • Martin WJ, Walton M, Harper J. Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout. Arthritis Rheum 2009; 60: 281-289.
    • (2009) Arthritis Rheum , vol.60 , pp. 281-289
    • Martin, W.J.1    Walton, M.2    Harper, J.3
  • 26
    • 62149135267 scopus 로고    scopus 로고
    • C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy
    • Tang Z, Lu B, Hatch E et al. C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol 2009; 20: 593-603.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 593-603
    • Tang, Z.1    Lu, B.2    Hatch, E.3
  • 29
    • 77749245829 scopus 로고    scopus 로고
    • Complement fragments C3a and C5a: The salt and pepper of the immune response
    • Sacks SH. Complement fragments C3a and C5a: the salt and pepper of the immune response. Eur J Immunol 2010; 40: 668-670.
    • (2010) Eur J Immunol , vol.40 , pp. 668-670
    • Sacks, S.H.1
  • 31
    • 0034670027 scopus 로고    scopus 로고
    • Targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock
    • Kildsgaard J, Hollmann TJ, Matthews KW et al. Targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol 2000; 165: 5406-5409.
    • (2000) J Immunol , vol.165 , pp. 5406-5409
    • Kildsgaard, J.1    Hollmann, T.J.2    Matthews, K.W.3
  • 32
    • 39149091052 scopus 로고    scopus 로고
    • Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: Opposing roles of C3a and C5a
    • Hollmann TJ, Mueller-Ortiz SL, Braun MC et al. Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a. Mol Immunol 2008; 45: 1907-1915.
    • (2008) Mol Immunol , vol.45 , pp. 1907-1915
    • Hollmann, T.J.1    Mueller-Ortiz, S.L.2    Braun, M.C.3
  • 34
    • 62549118640 scopus 로고    scopus 로고
    • C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse
    • Wenderfer SE, Wang H, Ke B et al. C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse. Mol Immunol 2009; 46: 1397-1404.
    • (2009) Mol Immunol , vol.46 , pp. 1397-1404
    • Wenderfer, S.E.1    Wang, H.2    Ke, B.3
  • 35
    • 0034739041 scopus 로고    scopus 로고
    • A role for the C3a anaphylatoxin receptor in the effector phase of asthma
    • Humbles AA, Lu B, Nilsson CA et al. A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature 2000; 406: 998-1001.
    • (2000) Nature , vol.406 , pp. 998-1001
    • Humbles, A.A.1    Lu, B.2    Nilsson, C.A.3
  • 38
    • 65249114882 scopus 로고    scopus 로고
    • A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells
    • Zhang X, Lewkowich IP, Kohl G et al. A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells. J Immunol 2009; 182: 5123-5130.
    • (2009) J Immunol , vol.182 , pp. 5123-5130
    • Zhang, X.1    Lewkowich, I.P.2    Kohl, G.3
  • 39
    • 70449555951 scopus 로고    scopus 로고
    • CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes
    • Niedermeier M, Reich B, Rodriguez GM et al. CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes. Proc Natl Acad Sci USA 2009; 106: 17892-17897.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 17892-17897
    • Niedermeier, M.1    Reich, B.2    Rodriguez, G.M.3
  • 40
    • 0033971775 scopus 로고    scopus 로고
    • Chemokines, chemokine receptors, and renal disease: From basic science to pathophysiologic and therapeutic studies
    • Segerer S, Nelson PJ, Schlondorff D. Chemokines, chemokine receptors, and renal disease: from basic science to pathophysiologic and therapeutic studies. J Am Soc Nephrol 2000; 11: 152-176. (Pubitemid 30020438)
    • (2000) Journal of the American Society of Nephrology , vol.11 , Issue.1 , pp. 152-176
    • Segerer, S.1    Nelson, P.J.2    Schlondorff, D.3
  • 41
    • 34249083152 scopus 로고    scopus 로고
    • Role of Chemokines for the Localization of Leukocyte Subsets in the Kidney
    • DOI 10.1016/j.semnephrol.2007.02.003, PII S0270929507000344, Mechanisms of Tissue Injury in Acute and Chronic Renal Disease
    • Segerer S, Schlondorff D. Role of chemokines for the localization of leukocyte subsets in the kidney. Semin Nephrol 2007; 27: 260-274. (Pubitemid 46802915)
    • (2007) Seminars in Nephrology , vol.27 , Issue.3 , pp. 260-274
    • Segerer, S.1    Schlondorff, D.2
  • 43
    • 0024978322 scopus 로고
    • Rapid induction of neutrophilendothelial adhesion by endothelial complement fixation
    • Marks RM, Todd III RF, Ward PA. Rapid induction of neutrophilendothelial adhesion by endothelial complement fixation. Nature 1989; 339: 314-317.
    • (1989) Nature , vol.339 , pp. 314-317
    • Marks, R.M.1    Todd Iii, R.F.2    Ward, P.A.3
  • 44
    • 0027160034 scopus 로고
    • CR3 (CD11b, CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions
    • Ross GD, Vetvicka V. CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Exp Immunol 1993; 92: 181-184. (Pubitemid 23151023)
    • (1993) Clinical and Experimental Immunology , vol.92 , Issue.2 , pp. 181-184
    • Ross, G.D.1    Vetvicka, V.2
  • 45
    • 0021984750 scopus 로고
    • Activation of phagocytic cells' C3 receptors for phagocytosis
    • Wright SD, Griffin Jr FM. Activation of phagocytic cells' C3 receptors for phagocytosis. J Leukoc Biol 1985; 38: 327-339. (Pubitemid 15243434)
    • (1985) Journal of Leukocyte Biology , vol.38 , Issue.2 , pp. 327-339
    • Wright, S.D.1    Griffin Jr., F.M.2
  • 46
    • 34547905051 scopus 로고    scopus 로고
    • Neutrophil activation via β2 integrins (CD11/CD18): Molecular mechanisms and clinical implications
    • DOI 10.1160/TH07-02-0156
    • Schymeinsky J, Mocsai A, Walzog B. Neutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms and clinical implications. Thromb Haemost 2007; 98: 262-273. (Pubitemid 47260290)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.2 , pp. 262-273
    • Schymeinsky, J.1    Mocsai, A.2    Walzog, B.3
  • 48
    • 68849091034 scopus 로고    scopus 로고
    • A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice
    • He S, Atkinson C, Qiao F et al. A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice. J Clin Invest 2009; 119: 2304-2316.
    • (2009) J Clin Invest , vol.119 , pp. 2304-2316
    • He, S.1    Atkinson, C.2    Qiao, F.3
  • 49
    • 0347480217 scopus 로고    scopus 로고
    • Negligible Role of Antibodies and C5 in Pregnancy Loss Associated Exclusively with C3-Dependent Mechanisms through Complement Alternative Pathway
    • DOI 10.1016/S1074-7613(03)00321-2
    • Mao D, Wu X, Deppong C et al. Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity 2003; 19: 813-822. (Pubitemid 37542302)
    • (2003) Immunity , vol.19 , Issue.6 , pp. 813-822
    • Mao, D.1    Wu, X.2    Deppong, C.3    Friend, L.D.4    Dolecki, G.5    Nelson, D.M.6    Molina, H.7
  • 50
    • 0029795542 scopus 로고    scopus 로고
    • The C5a chemoattractant receptor mediates mucosal defence to infection
    • DOI 10.1038/383086a0
    • Hopken UE, Lu B, Gerard NP et al. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 1996; 383: 86-89. (Pubitemid 26296466)
    • (1996) Nature , vol.383 , Issue.6595 , pp. 86-89
    • Hopken, U.E.1    Lu, B.2    Gerard, N.P.3    Gerard, C.4
  • 51
    • 0842321773 scopus 로고    scopus 로고
    • Role of Toll-Like Receptor 4 in Endotoxin-Induced Acute Renal Failure
    • Cunningham PN, Wang Y, Guo R et al. Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. J Immunol 2004; 172: 2629-2635. (Pubitemid 38182415)
    • (2004) Journal of Immunology , vol.172 , Issue.4 , pp. 2629-2635
    • Cunningham, P.N.1    Wang, Y.2    Guo, R.3    He, G.4    Quigg, R.J.5
  • 53
    • 0028971267 scopus 로고
    • Tubulointerstitial injury induced in rats by a monoclonal antibody which inhibits function of a membrane inhibitor of complement
    • Nomura A, Nishikawa K, Yuzawa Y et al. Tubulointerstitial injury induced in rats by a monoclonal antibody which inhibits function of a membrane inhibitor of complement. J Clin Invest 1995; 96: 2348-2356.
    • (1995) J Clin Invest , vol.96 , pp. 2348-2356
    • Nomura, A.1    Nishikawa, K.2    Yuzawa, Y.3
  • 54
    • 22544469404 scopus 로고    scopus 로고
    • Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis
    • Bao L, Osawe I, Haas M et al. Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritis. J Immunol 2005; 175: 1947-1955. (Pubitemid 41023102)
    • (2005) Journal of Immunology , vol.175 , Issue.3 , pp. 1947-1955
    • Bao, L.1    Osawe, I.2    Haas, M.3    Quigg, R.J.4
  • 55
    • 66449095349 scopus 로고    scopus 로고
    • Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells
    • Bao L, Haas M, Pippin J et al. Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells. J Clin Invest 2009; 119: 1264-1274.
    • (2009) J Clin Invest , vol.119 , pp. 1264-1274
    • Bao, L.1    Haas, M.2    Pippin, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.