-
1
-
-
4644290657
-
Treatment of pulmonary arterial hypertension
-
10.1056/NEJMra040291, 15459304
-
Humbert M, Sitbon O, Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004, 351(14):1425-1436. 10.1056/NEJMra040291, 15459304.
-
(2004)
N Engl J Med
, vol.351
, Issue.14
, pp. 1425-1436
-
-
Humbert, M.1
Sitbon, O.2
Simonneau, G.3
-
2
-
-
0037741441
-
Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension
-
10.1161/01.CIR.0000074226.20466.B1, 12796132
-
Sebkhi A, Strange JW, Phillips SC, Wharton J, Wilkins MR. Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension. Circulation 2003, 107(25):3230-3235. 10.1161/01.CIR.0000074226.20466.B1, 12796132.
-
(2003)
Circulation
, vol.107
, Issue.25
, pp. 3230-3235
-
-
Sebkhi, A.1
Strange, J.W.2
Phillips, S.C.3
Wharton, J.4
Wilkins, M.R.5
-
3
-
-
33847743922
-
Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension
-
10.1183/09031936.00081706, 17079256
-
Mathai SC, Girgis RE, Fisher MR, Champion HC, Housten-Harris T, Zaiman A, Hassoun PM. Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension. Eur Respir J 2007, 29(3):469-475. 10.1183/09031936.00081706, 17079256.
-
(2007)
Eur Respir J
, vol.29
, Issue.3
, pp. 469-475
-
-
Mathai, S.C.1
Girgis, R.E.2
Fisher, M.R.3
Champion, H.C.4
Housten-Harris, T.5
Zaiman, A.6
Hassoun, P.M.7
-
4
-
-
38049132717
-
Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling
-
10.1096/fj.06-7526com, 17679609
-
Kirsch M, Kemp-Harper B, Weissmann N, Grimminger F, Schmidt HH. Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling. Faseb J 2008, 22(1):30-40. 10.1096/fj.06-7526com, 17679609.
-
(2008)
Faseb J
, vol.22
, Issue.1
, pp. 30-40
-
-
Kirsch, M.1
Kemp-Harper, B.2
Weissmann, N.3
Grimminger, F.4
Schmidt, H.H.5
-
5
-
-
14944356027
-
Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells
-
10.1007/s00395-004-0504-5, 15739122
-
Tantini B, Manes A, Fiumana E, Pignatti C, Guarnieri C, Zannoli R, Branzi A, Galie N. Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells. Basic Res Cardiol 2005, 100(2):131-138. 10.1007/s00395-004-0504-5, 15739122.
-
(2005)
Basic Res Cardiol
, vol.100
, Issue.2
, pp. 131-138
-
-
Tantini, B.1
Manes, A.2
Fiumana, E.3
Pignatti, C.4
Guarnieri, C.5
Zannoli, R.6
Branzi, A.7
Galie, N.8
-
6
-
-
33746882463
-
Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity
-
Ikeda F, Nishimura R, Matsubara T, Hata K, Reddy SV, Yoneda T. Activation of NFAT signal in vivo leads to osteopenia associated with increased osteoclastogenesis and bone-resorbing activity. J Immunol 2006, 177(4):2384-2390.
-
(2006)
J Immunol
, vol.177
, Issue.4
, pp. 2384-2390
-
-
Ikeda, F.1
Nishimura, R.2
Matsubara, T.3
Hata, K.4
Reddy, S.V.5
Yoneda, T.6
-
7
-
-
33748929299
-
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function
-
10.1038/nature05097, 16988714
-
Heit JJ, Apelqvist AA, Gu X, Winslow MM, Neilson JR, Crabtree GR, Kim SK. Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function. Nature 2006, 443(7109):345-349. 10.1038/nature05097, 16988714.
-
(2006)
Nature
, vol.443
, Issue.7109
, pp. 345-349
-
-
Heit, J.J.1
Apelqvist, A.A.2
Gu, X.3
Winslow, M.M.4
Neilson, J.R.5
Crabtree, G.R.6
Kim, S.K.7
-
8
-
-
33947319817
-
Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation
-
10.1152/ajpcell.00590.2005, 17079331
-
Nilsson LM, Sun ZW, Nilsson J, Nordstrom I, Chen YW, Molkentin JD, Wide-Swensson D, Hellstrand P, Lydrup ML, Gomez MF. Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation. Am J Physiol Cell Physiol 2007, 292(3):C1167-1178. 10.1152/ajpcell.00590.2005, 17079331.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, Issue.3
-
-
Nilsson, L.M.1
Sun, Z.W.2
Nilsson, J.3
Nordstrom, I.4
Chen, Y.W.5
Molkentin, J.D.6
Wide-Swensson, D.7
Hellstrand, P.8
Lydrup, M.L.9
Gomez, M.F.10
-
9
-
-
34447529504
-
Nuclear translocation of calcineurin Abeta but not calcineurin Aalpha by platelet-derived growth factor in rat aortic smooth muscle
-
10.1152/ajpcell.00139.2005, 17303652
-
Jabr RI, Wilson AJ, Riddervold MH, Jenkins AH, Perrino BA, Clapp LH. Nuclear translocation of calcineurin Abeta but not calcineurin Aalpha by platelet-derived growth factor in rat aortic smooth muscle. Am J Physiol Cell Physiol 2007, 292(6):C2213-2225. 10.1152/ajpcell.00139.2005, 17303652.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, Issue.6
-
-
Jabr, R.I.1
Wilson, A.J.2
Riddervold, M.H.3
Jenkins, A.H.4
Perrino, B.A.5
Clapp, L.H.6
-
10
-
-
34548148938
-
Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation
-
10.1074/jbc.M611780200, 17533154
-
Nishida M, Onohara N, Sato Y, Suda R, Ogushi M, Tanabe S, Inoue R, Mori Y, Kurose H. Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation. J Biol Chem 2007, 282(32):23117-23128. 10.1074/jbc.M611780200, 17533154.
-
(2007)
J Biol Chem
, vol.282
, Issue.32
, pp. 23117-23128
-
-
Nishida, M.1
Onohara, N.2
Sato, Y.3
Suda, R.4
Ogushi, M.5
Tanabe, S.6
Inoue, R.7
Mori, Y.8
Kurose, H.9
-
11
-
-
0035130126
-
A calcineurin- and NFAT-dependent pathway regulates Myf5 gene expression in skeletal muscle reserve cells
-
Friday BB, Pavlath GK. A calcineurin- and NFAT-dependent pathway regulates Myf5 gene expression in skeletal muscle reserve cells. J Cell Sci 2001, 114(Pt 2):303-310.
-
(2001)
J Cell Sci
, vol.114
, Issue.PT 2
, pp. 303-310
-
-
Friday, B.B.1
Pavlath, G.K.2
-
12
-
-
34447499136
-
NFATc3 mediates chronic hypoxia-induced pulmonary arterial remodeling with alpha-actin up-regulation
-
10.1074/jbc.M702679200, 2754407, 17403661
-
de Frutos S, Spangler R, Alo D, Bosc LV. NFATc3 mediates chronic hypoxia-induced pulmonary arterial remodeling with alpha-actin up-regulation. J Biol Chem 2007, 282(20):15081-15089. 10.1074/jbc.M702679200, 2754407, 17403661.
-
(2007)
J Biol Chem
, vol.282
, Issue.20
, pp. 15081-15089
-
-
de Frutos, S.1
Spangler, R.2
Alo, D.3
Bosc, L.V.4
-
13
-
-
34547456414
-
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
-
10.1073/pnas.0610467104, 1903339,1903339, 17596340
-
Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci USA 2007, 104(27):11418-11423. 10.1073/pnas.0610467104, 1903339,1903339, 17596340.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.27
, pp. 11418-11423
-
-
Bonnet, S.1
Rochefort, G.2
Sutendra, G.3
Archer, S.L.4
Haromy, A.5
Webster, L.6
Hashimoto, K.7
Bonnet, S.N.8
Michelakis, E.D.9
-
14
-
-
0030973579
-
Transcription factors of the NFAT family: regulation and function
-
Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annul Rev Immunol 1997, 15:707-747.
-
(1997)
Annul Rev Immunol
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
15
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
10.1101/gad.1102703, 12975316
-
Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 2003, 17(18):2205-2232. 10.1101/gad.1102703, 12975316.
-
(2003)
Genes Dev
, vol.17
, Issue.18
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
16
-
-
15544368216
-
Store-operated calcium channels
-
10.1152/physrev.00057.2003, 15788710
-
Parekh AB, Putney JW. Store-operated calcium channels. Physiol Rev 2005, 85(2):757-810. 10.1152/physrev.00057.2003, 15788710.
-
(2005)
Physiol Rev
, vol.85
, Issue.2
, pp. 757-810
-
-
Parekh, A.B.1
Putney, J.W.2
-
17
-
-
33750612788
-
TRP channels, CCE, and the pulmonary vascular smooth muscle
-
10.1080/10739680600930313, 17085427
-
Remillard CV, Yuan JX. TRP channels, CCE, and the pulmonary vascular smooth muscle. Microcirculation 2006, 13(8):671-692. 10.1080/10739680600930313, 17085427.
-
(2006)
Microcirculation
, vol.13
, Issue.8
, pp. 671-692
-
-
Remillard, C.V.1
Yuan, J.X.2
-
18
-
-
34447286761
-
Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry
-
Zhang S, Patel HH, Murray F, Remillard CV, Schach C, Thistlethwaite PA, Insel PA, Yuan JX. Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry. Am J Physio Lung Cell Mol Physiol 2007, 292(5):L1202-1210.
-
(2007)
Am J Physio Lung Cell Mol Physiol
, vol.292
, Issue.5
-
-
Zhang, S.1
Patel, H.H.2
Murray, F.3
Remillard, C.V.4
Schach, C.5
Thistlethwaite, P.A.6
Insel, P.A.7
Yuan, J.X.8
-
19
-
-
33746543743
-
Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells
-
10.1161/01.RES.0000227551.68124.98, 16709899
-
Wang J, Weigand L, Lu W, Sylvester JT, Semenza GL, Shimoda LA. Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells. Circ Res 2006, 98(12):1528-1537. 10.1161/01.RES.0000227551.68124.98, 16709899.
-
(2006)
Circ Res
, vol.98
, Issue.12
, pp. 1528-1537
-
-
Wang, J.1
Weigand, L.2
Lu, W.3
Sylvester, J.T.4
Semenza, G.L.5
Shimoda, L.A.6
-
20
-
-
0344927128
-
Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells
-
Fantozzi I, Zhang S, Platoshyn O, Remillard CV, Cowling RT, Yuan JX. Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 2003, 285(6):L1233-1245.
-
(2003)
Am J Physiol Lung Cell Mol Physiol
, vol.285
, Issue.6
-
-
Fantozzi, I.1
Zhang, S.2
Platoshyn, O.3
Remillard, C.V.4
Cowling, R.T.5
Yuan, J.X.6
-
21
-
-
34249084477
-
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange
-
10.1073/pnas.0606728103, 1748182, 17142322
-
Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederosy Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T. Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange. Proc Natl Acad Sci USA 2006, 103(50):19093-19098. 10.1073/pnas.0606728103, 1748182, 17142322.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.50
, pp. 19093-19098
-
-
Weissmann, N.1
Dietrich, A.2
Fuchs, B.3
Kalwa, H.4
Ay, M.5
Dumitrascu, R.6
Olschewski, A.7
Storch, U.8
Mederosy Schnitzler, M.9
Ghofrani, H.A.10
Schermuly, R.T.11
Pinkenburg, O.12
Seeger, W.13
Grimminger, F.14
Gudermann, T.15
-
22
-
-
8444223158
-
Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes
-
10.1164/rccm.200312-1668OC, 15317671
-
Kunichika N, Landsberg JW, Yu Y, Kunichika H, Thistlethwaite PA, Rubin LJ, Yuan JX. Bosentan inhibits transient receptor potential channel expression in pulmonary vascular myocytes. Am J Respir Crit Care Med 2004, 170(10):1101-1107. 10.1164/rccm.200312-1668OC, 15317671.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, Issue.10
, pp. 1101-1107
-
-
Kunichika, N.1
Landsberg, J.W.2
Yu, Y.3
Kunichika, H.4
Thistlethwaite, P.A.5
Rubin, L.J.6
Yuan, J.X.7
-
23
-
-
0021895138
-
A new generation of Ca2+ indicators with greatly improved fluorescence properties
-
Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985, 260(6):3440-3450.
-
(1985)
J Biol Chem
, vol.260
, Issue.6
, pp. 3440-3450
-
-
Grynkiewicz, G.1
Poenie, M.2
Tsien, R.Y.3
-
24
-
-
4143121002
-
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats
-
10.1152/ajplung.00449.2003, 15155272
-
Pauvert O, Bonnet S, Rousseau E, Marthan R, Savineau JP. Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol 2004, 287(3):L577-583. 10.1152/ajplung.00449.2003, 15155272.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, Issue.3
-
-
Pauvert, O.1
Bonnet, S.2
Rousseau, E.3
Marthan, R.4
Savineau, J.P.5
-
25
-
-
0033514921
-
Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel
-
10.1073/pnas.96.5.2060, 26736, 10051594
-
Vannier B, Peyton M, Boulay G, Brown D, Qin N, Jiang M, Zhu X, Birnbaumer L. Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel. Proc Natl Acad Sci USA 1999, 96(5):2060-2064. 10.1073/pnas.96.5.2060, 26736, 10051594.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.5
, pp. 2060-2064
-
-
Vannier, B.1
Peyton, M.2
Boulay, G.3
Brown, D.4
Qin, N.5
Jiang, M.6
Zhu, X.7
Birnbaumer, L.8
-
26
-
-
0036318217
-
Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation
-
Sweeney M, Yu Y, Platoshyn O, Zhang S, McDaniel SS, Yuan JX. Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 2002, 283(1):L144-155.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
, Issue.1
-
-
Sweeney, M.1
Yu, Y.2
Platoshyn, O.3
Zhang, S.4
McDaniel, S.S.5
Yuan, J.X.6
-
27
-
-
0034999284
-
Upregulated TRP and enhanced capacitative Ca2+ entry in human pulmonary artery myocytes during proliferation
-
Golovina VA, Platoshyn O, Bailey CL, Wang J, Limsuwan A, Sweeney M, Rubin LJ, Yuan JX. Upregulated TRP and enhanced capacitative Ca2+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 2001, 280(2):H746-755.
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
, Issue.2
-
-
Golovina, V.A.1
Platoshyn, O.2
Bailey, C.L.3
Wang, J.4
Limsuwan, A.5
Sweeney, M.6
Rubin, L.J.7
Yuan, J.X.8
-
28
-
-
20644466433
-
NFAT proteins: key regulators of T-cell development and function
-
10.1038/nri1632, 15928679
-
Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 2005, 5(6):472-484. 10.1038/nri1632, 15928679.
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.6
, pp. 472-484
-
-
Macian, F.1
-
29
-
-
0037623284
-
Primary pulmonary hypertension
-
10.1016/S0140-6736(03)13167-4, 12737878
-
Runo JR, Loyd JE. Primary pulmonary hypertension. Lancet 2003, 361(9368):1533-1544. 10.1016/S0140-6736(03)13167-4, 12737878.
-
(2003)
Lancet
, vol.361
, Issue.9368
, pp. 1533-1544
-
-
Runo, J.R.1
Loyd, J.E.2
-
30
-
-
0035198893
-
SGC and PDE5 are elevated in lambs with increasedpulmonary blood flow and pulmonary hypertension
-
Black SM, Sanchez LS, Mata-Greenwood E, Bekker JM, Steinhorn RH, Fineman JR. sGC and PDE5 are elevated in lambs with increasedpulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2001, 281(5):L1051-1057.
-
(2001)
Am J Physiol Lung Cell Mol Physiol
, vol.281
, Issue.5
-
-
Black, S.M.1
Sanchez, L.S.2
Mata-Greenwood, E.3
Bekker, J.M.4
Steinhorn, R.H.5
Fineman, J.R.6
-
31
-
-
20844456405
-
Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy
-
10.1161/01.CIR.0000143836.40431.F5, 15466636
-
Rondelet B, Kerbaul F, Van Beneden R, Motte S, Fesler P, Hubloue I, Remmelink M, Brimioulle S, Salmon I, Ketelslegers JM, et al. Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy. Circulation 2004, 110(15):2220-2225. 10.1161/01.CIR.0000143836.40431.F5, 15466636.
-
(2004)
Circulation
, vol.110
, Issue.15
, pp. 2220-2225
-
-
Rondelet, B.1
Kerbaul, F.2
Van Beneden, R.3
Motte, S.4
Fesler, P.5
Hubloue, I.6
Remmelink, M.7
Brimioulle, S.8
Salmon, I.9
Ketelslegers, J.M.10
-
32
-
-
21544444144
-
Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells
-
10.1164/rccm.200411-1587OC, 15817798
-
Wharton J, Strange JW, Moller GM, Growcott EJ, Ren X, Franklyn AP, Phillips SC, Wilkins MR. Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells. Am J Respir Crit Care Med 2005, 172(1):105-113. 10.1164/rccm.200411-1587OC, 15817798.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, Issue.1
, pp. 105-113
-
-
Wharton, J.1
Strange, J.W.2
Moller, G.M.3
Growcott, E.J.4
Ren, X.5
Franklyn, A.P.6
Phillips, S.C.7
Wilkins, M.R.8
-
33
-
-
10744233302
-
Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats
-
10.1164/rccm.200302-282OC, 12958054
-
Schermuly RT, Kreisselmeier KP, Ghofrani HA, Yilmaz H, Butrous G, Ermert L, Ermert M, Weissmann N, Rose F, Guenther A, Walmrath D, Seeger W, Grimminger F. Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats. Am J Respir Crit Care Med 2004, 169(1):39-45. 10.1164/rccm.200302-282OC, 12958054.
-
(2004)
Am J Respir Crit Care Med
, vol.169
, Issue.1
, pp. 39-45
-
-
Schermuly, R.T.1
Kreisselmeier, K.P.2
Ghofrani, H.A.3
Yilmaz, H.4
Butrous, G.5
Ermert, L.6
Ermert, M.7
Weissmann, N.8
Rose, F.9
Guenther, A.10
Walmrath, D.11
Seeger, W.12
Grimminger, F.13
-
34
-
-
26444540768
-
Reversal of experimental pulmonary hypertension by PDGF inhibition
-
10.1172/JCI24838, 1236676, 16200212
-
Schermuly RT, Dony E, Ghofrani HA, Pullamsetti S, Savai R, Roth M, Sydykov A, Lai YJ, Weissmann N, Seeger W, Grimminger F. Reversal of experimental pulmonary hypertension by PDGF inhibition. J Clin Invest 2005, 115(10):2811-2821. 10.1172/JCI24838, 1236676, 16200212.
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2811-2821
-
-
Schermuly, R.T.1
Dony, E.2
Ghofrani, H.A.3
Pullamsetti, S.4
Savai, R.5
Roth, M.6
Sydykov, A.7
Lai, Y.J.8
Weissmann, N.9
Seeger, W.10
Grimminger, F.11
-
35
-
-
20944432353
-
Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system
-
Krick S, Hanze J, Eul B, Savai R, Seay U, Grimminger F, Lohmeyer J, Klepetko W, Seeger W, Rose F. Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system. Faseb J 2005, 19(7):857-859.
-
(2005)
Faseb J
, vol.19
, Issue.7
, pp. 857-859
-
-
Krick, S.1
Hanze, J.2
Eul, B.3
Savai, R.4
Seay, U.5
Grimminger, F.6
Lohmeyer, J.7
Klepetko, W.8
Seeger, W.9
Rose, F.10
-
36
-
-
52949096809
-
Sildenafil inhibits human pulmonary artery smooth muscle cell proliferation by decreasing capacitative Ca2+ entry
-
10.1254/jphs.08069FP, 18818482
-
Wang C, Wang J, Zhao L, Wang YX, Liu J, Shi LP, Xu M, Wang C. Sildenafil inhibits human pulmonary artery smooth muscle cell proliferation by decreasing capacitative Ca2+ entry. J Pharmacol Sci 2008, 108(1):71-78. 10.1254/jphs.08069FP, 18818482.
-
(2008)
J Pharmacol Sci
, vol.108
, Issue.1
, pp. 71-78
-
-
Wang, C.1
Wang, J.2
Zhao, L.3
Wang, Y.X.4
Liu, J.5
Shi, L.P.6
Xu, M.7
Wang, C.8
-
37
-
-
34247168120
-
Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors
-
10.1620/tjem.211.309, 17409670
-
Fukumoto Y, Tawara S, Shimokawa H. Recent progress in the treatment of pulmonary arterial hypertension: expectation for rho-kinase inhibitors. Tohoku J Exp Med 2007, 211(4):309-320. 10.1620/tjem.211.309, 17409670.
-
(2007)
Tohoku J Exp Med
, vol.211
, Issue.4
, pp. 309-320
-
-
Fukumoto, Y.1
Tawara, S.2
Shimokawa, H.3
-
38
-
-
1442330339
-
Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G
-
10.1073/pnas.0304471101, 357000, 14983059
-
Kwan HY, Huang Y, Yao X. Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. Proc Natl Acad Sci USA 2004, 101(8):2625-2630. 10.1073/pnas.0304471101, 357000, 14983059.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.8
, pp. 2625-2630
-
-
Kwan, H.Y.1
Huang, Y.2
Yao, X.3
-
39
-
-
51749086155
-
Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6
-
10.1113/jphysiol.2008.156083, 2652196, 18617565
-
Takahashi S, Lin H, Geshi N, Mori Y, Kawarabayashi Y, Takami N, Mori MX, Honda A, Inoue R. Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol 2008, 586(Pt 17):4209-4223. 10.1113/jphysiol.2008.156083, 2652196, 18617565.
-
(2008)
J Physiol
, vol.586
, Issue.PT 17
, pp. 4209-4223
-
-
Takahashi, S.1
Lin, H.2
Geshi, N.3
Mori, Y.4
Kawarabayashi, Y.5
Takami, N.6
Mori, M.X.7
Honda, A.8
Inoue, R.9
-
40
-
-
67650032865
-
Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation
-
10.1152/ajpheart.01130.2008, 2711742, 19502552
-
Chen J, Crossland RF, Noorani MM, Marrelli SP. Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation. Am J Physiol Heart Circ Physiol 2009, 297(1):H417-424. 10.1152/ajpheart.01130.2008, 2711742, 19502552.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.1
-
-
Chen, J.1
Crossland, R.F.2
Noorani, M.M.3
Marrelli, S.P.4
-
41
-
-
0037143710
-
Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes
-
10.1073/pnas.162100799, 123262, 12177418
-
Fiedler B, Lohmann SM, Smolenski A, Linnemuller S, Pieske B, Schroder F, Molkentin JD, Drexler H, Wollert KC. Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci USA 2002, 99(17):11363-11368. 10.1073/pnas.162100799, 123262, 12177418.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.17
, pp. 11363-11368
-
-
Fiedler, B.1
Lohmann, S.M.2
Smolenski, A.3
Linnemuller, S.4
Pieske, B.5
Schroder, F.6
Molkentin, J.D.7
Drexler, H.8
Wollert, K.C.9
-
42
-
-
0031019855
-
Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression
-
10.1038/385260a0, 9000075
-
Hardingham GE, Chawla S, Johnson CM, Bading H. Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 1997, 385(6613):260-265. 10.1038/385260a0, 9000075.
-
(1997)
Nature
, vol.385
, Issue.6613
, pp. 260-265
-
-
Hardingham, G.E.1
Chawla, S.2
Johnson, C.M.3
Bading, H.4
-
43
-
-
33847372100
-
Upregulation of TRPC1 in thedevelopment of cardiac hypertrophy
-
10.1016/j.yjmcc.2006.10.020, 17174323
-
Ohba T, Watanabe H, Murakami M, Takahashi Y, Iino K, Kuromitsu S, Mori Y, Ono K, Iijima T, Ito H. Upregulation of TRPC1 in thedevelopment of cardiac hypertrophy. J Mol Cell Cardiol 2007, 42(3):498-507. 10.1016/j.yjmcc.2006.10.020, 17174323.
-
(2007)
J Mol Cell Cardiol
, vol.42
, Issue.3
, pp. 498-507
-
-
Ohba, T.1
Watanabe, H.2
Murakami, M.3
Takahashi, Y.4
Iino, K.5
Kuromitsu, S.6
Mori, Y.7
Ono, K.8
Iijima, T.9
Ito, H.10
-
44
-
-
12244275742
-
NFAT regulation in smooth muscle
-
10.1016/S1050-1738(02)00212-8, 12586440
-
Hill-Eubanks DC, Gomez MF, Stevenson AS, Nelson MT. NFAT regulation in smooth muscle. Trends Cardiovasc Med 2003, 13(2):56-62. 10.1016/S1050-1738(02)00212-8, 12586440.
-
(2003)
Trends Cardiovasc Med
, vol.13
, Issue.2
, pp. 56-62
-
-
Hill-Eubanks, D.C.1
Gomez, M.F.2
Stevenson, A.S.3
Nelson, M.T.4
-
45
-
-
34447096652
-
Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes
-
10.1016/j.ceca.2007.03.007, 17572487
-
Gwack Y, Feske S, Srikanth S, Hogan PG, Rao A. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell calcium 2007, 42(2):145-156. 10.1016/j.ceca.2007.03.007, 17572487.
-
(2007)
Cell calcium
, vol.42
, Issue.2
, pp. 145-156
-
-
Gwack, Y.1
Feske, S.2
Srikanth, S.3
Hogan, P.G.4
Rao, A.5
-
46
-
-
0027418496
-
Transcriptional regulation during cardiac growth and development
-
10.1146/annurev.ph.55.030193.000453, 8466192
-
Chien KR, Zhu H, Knowlton KU, Miller-Hance W, van-Bilsen M, O'Brien TX, Evans SM. Transcriptional regulation during cardiac growth and development. Annu Rev Physiol 1993, 55:77-95. 10.1146/annurev.ph.55.030193.000453, 8466192.
-
(1993)
Annu Rev Physiol
, vol.55
, pp. 77-95
-
-
Chien, K.R.1
Zhu, H.2
Knowlton, K.U.3
Miller-Hance, W.4
van-Bilsen, M.5
O'Brien, T.X.6
Evans, S.M.7
-
47
-
-
0030969371
-
The cellular and molecular response of cardiac myocytes to mechanical stress
-
10.1146/annurev.physiol.59.1.551, 9074777
-
Sadoshima J, Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol 1997, 59:551-571. 10.1146/annurev.physiol.59.1.551, 9074777.
-
(1997)
Annu Rev Physiol
, vol.59
, pp. 551-571
-
-
Sadoshima, J.1
Izumo, S.2
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