-
1
-
-
67651102996
-
The protective effects of garlic extract against acetaminophen-induced oxidative stress and glutathione depletion
-
Anoush M, Eghbal MA, Fathiazad F, et al. (2009). The protective effects of garlic extract against acetaminophen-induced oxidative stress and glutathione depletion. Pak J Biol Sci 12:765-71.
-
(2009)
Pak J Biol Sci
, vol.12
, pp. 765-771
-
-
Anoush, M.1
Eghbal, M.A.2
Fathiazad, F.3
-
2
-
-
0033105564
-
Methimazole toxicity in rodents: Covalent binding in the olfactory mucosa and detection of glial fibrillary acidic protein in the olfactory bulb
-
Bergman U, Brittebo, EB. (1999). Methimazole toxicity in rodents: covalent binding in the olfactory mucosa and detection of glial fibrillary acidic protein in the olfactory bulb. Toxicol Appl Pharmacol 155:190-200.
-
(1999)
Toxicol Appl Pharmacol
, vol.155
, pp. 190-200
-
-
Bergman, U.1
Brittebo, E.B.2
-
3
-
-
0041805226
-
Methimazoleinduced damage in the olfactory mucosa: Effects on ultrastructure and glutathione levels
-
Bergström U, Giovanetti A, Piras E, Brittebo EB. (2003). Methimazoleinduced damage in the olfactory mucosa: effects on ultrastructure and glutathione levels. Toxicol Pathol 31:379-87.
-
(2003)
Toxicol Pathol
, vol.31
, pp. 379-387
-
-
Bergström, U.1
Giovanetti, A.2
Piras, E.3
Brittebo, E.B.4
-
4
-
-
0037237973
-
Antioxidants, oxidative damage, and oxygen deprivation stress: A review
-
Blokhina O, Virolainen E, Fagerstedt KV. (2003). Antioxidants, oxidative damage, and oxygen deprivation stress: a review. Ann Bot 91:179-94.
-
(2003)
Ann Bot
, vol.91
, pp. 179-194
-
-
Blokhina, O.1
Virolainen, E.2
Fagerstedt, K.V.3
-
5
-
-
0028868002
-
Metabolism-dependent toxicity of methimazole in the olfactory nasal mucosa
-
Brittebo EB. (1995). Metabolism-dependent toxicity of methimazole in the olfactory nasal mucosa. Pharmacol Toxicol 76:76-9.
-
(1995)
Pharmacol Toxicol
, vol.76
, pp. 76-79
-
-
Brittebo, E.B.1
-
6
-
-
0029920243
-
The assessment of flavin-containing monooxygenase activity in intact animals
-
Damani LA, Nnane IP. (1996). The assessment of flavin-containing monooxygenase activity in intact animals. Drug Metabol Drug Interact 13:1-28.
-
(1996)
Drug Metabol Drug Interact
, vol.13
, pp. 1-28
-
-
Damani, L.A.1
Nnane, I.P.2
-
7
-
-
0026687088
-
Metabolism of benzimidazoline-2-thiones by rat hepatic microsomes and dog liver flavincontaining monooxygenase
-
Decker CJ, Doerge DR, Cashman J.R. (1992). Metabolism of benzimidazoline-2-thiones by rat hepatic microsomes and dog liver flavincontaining monooxygenase. Chem Res Toxicol 5:726-33.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 726-733
-
-
Decker, C.J.1
Doerge, D.R.2
Cashman, J.R.3
-
8
-
-
4444237412
-
H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation
-
Eghbal MA, Pennefather PS, O'Brien PJ. (2004). H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. Toxicology 203:69-76.
-
(2004)
Toxicology
, vol.203
, pp. 69-76
-
-
Eghbal, M.A.1
Pennefather, P.S.2
O'Brien, P.J.3
-
9
-
-
70350339650
-
Thyroid gland: Antithyroid therapy-best choice of drug and dose
-
Franklyn JA. (2009). Thyroid gland: antithyroid therapy-best choice of drug and dose. Nat Rev Endocrinol 5:592-4.
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 592-594
-
-
Franklyn, J.A.1
-
10
-
-
0037058249
-
Idiosyncratic NSAID drug induced oxidative stress
-
Galati G, Tafazoli S, Sabzevari O, et al. (2002). Idiosyncratic NSAID drug induced oxidative stress. Chem Biol Interact 142:25-41.
-
(2002)
Chem Biol Interact
, vol.142
, pp. 25-41
-
-
Galati, G.1
Tafazoli, S.2
Sabzevari, O.3
-
11
-
-
73349105618
-
Hepatotoxicity induced by methimazole in a previously health patient
-
Gallelli L, Staltari O, Palleria C, et al. (2009). Hepatotoxicity induced by methimazole in a previously health patient. Curr Drug Saf 4:204-6.
-
(2009)
Curr Drug Saf
, vol.4
, pp. 204-206
-
-
Gallelli, L.1
Staltari, O.2
Palleria, C.3
-
12
-
-
0029125565
-
Olfactory toxicity of methimazole: Dose-response and structure-Activity studies and characterization of flavin-containing monooxygenase activity in the Long-Evans rat olfactory mucosa
-
Genter MB, Deamer NJ, Blake BL, et al. (1995). Olfactory toxicity of methimazole: dose-response and structure-Activity studies and characterization of flavin-containing monooxygenase activity in the Long-Evans rat olfactory mucosa. Toxicol Pathol 23:477-86.
-
(1995)
Toxicol Pathol
, vol.23
, pp. 477-486
-
-
Genter, M.B.1
Deamer, N.J.2
Blake, B.L.3
-
13
-
-
72449195814
-
Two cases of serious hepatic injury caused by antithyroid drugs. [Article in Polish]
-
Grzywa M, Orlowska-Florek R, Grzywa-Celinska A. (2009). Two cases of serious hepatic injury caused by antithyroid drugs. [Article in Polish]. Endokrynol Pol 60:396-400.
-
(2009)
Endokrynol Pol
, vol.60
, pp. 396-400
-
-
Grzywa, M.1
Orlowska-Florek, R.2
Grzywa-Celinska, A.3
-
14
-
-
0022398523
-
Pharmacokinetics of methimazole in humans
-
Hengstmann JH, Hohn H. (1985). Pharmacokinetics of methimazole in humans. Klin Wochenschr 63:1212-17.
-
(1985)
Klin Wochenschr
, vol.63
, pp. 1212-1217
-
-
Hengstmann, J.H.1
Hohn, H.2
-
15
-
-
34447518685
-
Cytotoxicity of chloroquine in isolated rat hepatocytes
-
Jamshidzadeh A, Niknahad H, Kashafi H. (2007). Cytotoxicity of chloroquine in isolated rat hepatocytes. J Appl Toxicol 27:322-6.
-
(2007)
J Appl Toxicol
, vol.27
, pp. 322-326
-
-
Jamshidzadeh, A.1
Niknahad, H.2
Kashafi, H.3
-
16
-
-
0021995799
-
Loss of rat liver microsomal cytochrome P-450 during methimazole metabolism. Role of flavincontaining monooxygenase
-
Kedderis GL, Rickert DE. (1985). Loss of rat liver microsomal cytochrome P-450 during methimazole metabolism. Role of flavincontaining monooxygenase. Drug Metab Dispos 13:58-61.
-
(1985)
Drug Metab Dispos
, vol.13
, pp. 58-61
-
-
Kedderis, G.L.1
Rickert, D.E.2
-
17
-
-
0026094923
-
1-bromoalkanes as new potent nontoxic glutathione depletors in isolated rat hepatocytes
-
Khan S, O'Brien PJ. (1991). 1-bromoalkanes as new potent nontoxic glutathione depletors in isolated rat hepatocytes. Biochem Biophys Res Commun 179:436-41.
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 436-441
-
-
Khan, S.1
O'Brien, P.J.2
-
18
-
-
0034011876
-
Status of glutathione and other thiols and disulfides in human plasma
-
Kleinman WA, Richie Jr JP,. (2000). Status of glutathione and other thiols and disulfides in human plasma. Biochem Pharmacol 60:19-29.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 19-29
-
-
Kleinman, W.A.1
Richie Jr., J.P.2
-
19
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol Rev 87:99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
20
-
-
0026554428
-
Evaluation of the probe 20,70-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
-
Lebel CP, Ischiropoulos H, Bondy SC. (1992). Evaluation of the probe 20,70-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5:227-31.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 227-231
-
-
Lebel, C.P.1
Ischiropoulos, H.2
Bondy, S.C.3
-
21
-
-
0018082331
-
Metabolism of methimazole by rat liver cytochrome P-450-containing monoxygenases
-
Lee PW, Neal RA. (1978). Metabolism of methimazole by rat liver cytochrome P-450-containing monoxygenases. Drug Metab Dispos 6:591-600.
-
(1978)
Drug Metab Dispos
, vol.6
, pp. 591-600
-
-
Lee, P.W.1
Neal, R.A.2
-
22
-
-
77955329997
-
Liver failure due to antithyroid drugs: Report of a case and literature review
-
Livadas S, Xyrafis X, Economou F, et al. (2010). Liver failure due to antithyroid drugs: report of a case and literature review. Endocrine 38:24-8.
-
(2010)
Endocrine
, vol.38
, pp. 24-28
-
-
Livadas, S.1
Xyrafis, X.2
Economou, F.3
-
23
-
-
79951574562
-
Sulfenic acids as reactive intermediates in xenobiotic metabolism
-
Mansuy D, Dansette PM. (2011). Sulfenic acids as reactive intermediates in xenobiotic metabolism. Arch Biochem Biophys 507:174-85.
-
(2011)
Arch Biochem Biophys
, vol.507
, pp. 174-185
-
-
Mansuy, D.1
Dansette, P.M.2
-
24
-
-
0036186560
-
Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats
-
Masubuchi Y, Nakayama S, Horie T. (2002). Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats. Hepatology 35:544-51.
-
(2002)
Hepatology
, vol.35
, pp. 544-551
-
-
Masubuchi, Y.1
Nakayama, S.2
Horie, T.3
-
25
-
-
0034104597
-
Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs
-
Masubuchi Y, Yamada S, Horie T. (2000). Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther 292:982-7.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 982-987
-
-
Masubuchi, Y.1
Yamada, S.2
Horie, T.3
-
26
-
-
0025219875
-
Myeloperoxidase catalysed cooxidative metabolism of methimazole: Oxidation of glutathione and NADH by free radical intermediates
-
McGirr LG, Jatoe SD, O'Brien PJ. (1990). Myeloperoxidase catalysed cooxidative metabolism of methimazole: oxidation of glutathione and NADH by free radical intermediates. Chem Biol Interact 73:279-95.
-
(1990)
Chem Biol Interact
, vol.73
, pp. 279-295
-
-
McGirr, L.G.1
Jatoe, S.D.2
O'Brien, P.J.3
-
27
-
-
59049105100
-
Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes
-
Mehta R, Wong L, O'Brien PJ. (2009). Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes. Chem Biol Interact 178:317-23.
-
(2009)
Chem Biol Interact
, vol.178
, pp. 317-323
-
-
Mehta, R.1
Wong, L.2
O'Brien, P.J.3
-
28
-
-
1242314244
-
Methimazole-induced cholestatic jaundice
-
Mikhail NE. (2004). Methimazole-induced cholestatic jaundice. South Med J 97:178-82.
-
(2004)
South Med J
, vol.97
, pp. 178-182
-
-
Mikhail, N.E.1
-
29
-
-
0032946198
-
Metabolism-dependent hepatotoxicity of methimazole in mice depleted of glutathione
-
Mizutani T, Murakami M, Shirai M, et al. (1999). Metabolism-dependent hepatotoxicity of methimazole in mice depleted of glutathione. J Appl Toxicol 19:193-8.
-
(1999)
J Appl Toxicol
, vol.19
, pp. 193-198
-
-
Mizutani, T.1
Murakami, M.2
Shirai, M.3
-
30
-
-
0034122751
-
Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: Structure-toxicity and metabolic studies
-
Mizutani T, Yoshida K, Murakami M, et al. (2000). Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies. Chem Res Toxicol 13:170-6.
-
(2000)
Chem Res Toxicol
, vol.13
, pp. 170-176
-
-
Mizutani, T.1
Yoshida, K.2
Murakami, M.3
-
31
-
-
73349136974
-
Role of free radicals in liver diseases
-
Muriel P. (2009). Role of free radicals in liver diseases. Hepatol Int 3:526-36.
-
(2009)
Hepatol Int
, vol.3
, pp. 526-536
-
-
Muriel, P.1
-
32
-
-
0016259426
-
S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase
-
Poulsen LL, Hyslop RM, Ziegler DM. (1974). S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase. Biochem Pharmacol 23:3431-40.
-
(1974)
Biochem Pharmacol
, vol.23
, pp. 3431-3440
-
-
Poulsen, L.L.1
Hyslop, R.M.2
Ziegler, D.M.3
-
33
-
-
0035451601
-
Mechanism of clofibrate hepatotoxicity: Mitochondrial damage and oxidative stress in hepatocytes
-
Qu B, Li QT, Wong KP, et al. (2001). Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes. Free Radic Biol Med 31:659-69.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 659-669
-
-
Qu, B.1
Li, Q.T.2
Wong, K.P.3
-
34
-
-
0036318194
-
Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,40-dithiodipyridine
-
Riener CK, Kada G, Gruber HJ. (2002). Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,40-dithiodipyridine. Anal Bioanal Chem 373:266-76.
-
(2002)
Anal Bioanal Chem
, vol.373
, pp. 266-276
-
-
Riener, C.K.1
Kada, G.2
Gruber, H.J.3
-
35
-
-
73449143152
-
Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-Acetylcysteine
-
Saito C, Zwingmann C, Jaeschke H. (2010). Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-Acetylcysteine. Hepatology 51:246-54.
-
(2010)
Hepatology
, vol.51
, pp. 246-254
-
-
Saito, C.1
Zwingmann, C.2
Jaeschke, H.3
-
36
-
-
0022966847
-
Methimazoleassociated cholestatic liver injury: Case report and brief literature review
-
Schmidt G, Borsch G, Muller KM, Wegener M. (1986). Methimazoleassociated cholestatic liver injury: case report and brief literature review. Hepatogastroenterology 33:244-6.
-
(1986)
Hepatogastroenterology
, vol.33
, pp. 244-246
-
-
Schmidt, G.1
Borsch, G.2
Muller, K.M.3
Wegener, M.4
-
37
-
-
4444260621
-
The cytotoxic mechanism of glyoxal involves oxidative stress
-
Shangari N, O'Brien PJ. (2004). The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol 68:1433-42.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1433-1442
-
-
Shangari, N.1
O'Brien, P.J.2
-
38
-
-
0019730383
-
The metabolism of [2-14C]methimazole in the rat
-
Skellern GG, Steer S. (1981). The metabolism of [2-14C]methimazole in the rat. Xenobiotica 11:627-34.
-
(1981)
Xenobiotica
, vol.11
, pp. 627-634
-
-
Skellern, G.G.1
Steer, S.2
-
40
-
-
18744364709
-
Oxidative stress mediated idiosyncratic drug toxicity
-
Tafazoli S, Spehar DD, O'Brien PJ. (2005). Oxidative stress mediated idiosyncratic drug toxicity. Drug Metab Rev 37:311-25.
-
(2005)
Drug Metab Rev
, vol.37
, pp. 311-325
-
-
Tafazoli, S.1
Spehar, D.D.2
O'Brien, P.J.3
-
41
-
-
0015231922
-
The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450
-
Tephly TR, Hibbeln P. (1971). The effect of cobalt chloride administration on the synthesis of hepatic microsomal cytochrome P-450. Biochem Biophys Res Commun 42:589-95.
-
(1971)
Biochem Biophys Res Commun
, vol.42
, pp. 589-595
-
-
Tephly, T.R.1
Hibbeln, P.2
-
42
-
-
67649742556
-
Idiosyncratic drug-induced agranulocytosis: Possible mechanisms and management
-
Tesfa D, Keisu M, Palmblad J. (2009). Idiosyncratic drug-induced agranulocytosis: possible mechanisms and management. Am J Hematol 84:428-34.
-
(2009)
Am J Hematol
, vol.84
, pp. 428-434
-
-
Tesfa, D.1
Keisu, M.2
Palmblad, J.3
-
43
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
Valko M, Leibfritz D, Moncol J, et al. (2007). Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44-84.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
-
44
-
-
0036001059
-
Methimazole-induced hepatotoxicity
-
Woeber KA. (2002). Methimazole-induced hepatotoxicity. Endocr Pract 8:222-4.
-
(2002)
Endocr Pract
, vol.8
, pp. 222-224
-
-
Woeber, K.A.1
-
45
-
-
0036471379
-
Identification of a-dicarbonyl scavengers for cellular protection against carbonyl stress
-
Wondrak GT, Cervantes-Laurean D, Roberts MJ, et al. (2002). Identification of a-dicarbonyl scavengers for cellular protection against carbonyl stress. Biochem Pharmacol 63:361-73.
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 361-373
-
-
Wondrak, G.T.1
Cervantes-Laurean, D.2
Roberts, M.J.3
-
46
-
-
79956117400
-
The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5
-
Xie F, Zhou X, Genter MB, et al. (2011). The tissue-specific toxicity of methimazole in the mouse olfactory mucosa is partly mediated through target-tissue metabolic activation by CYP2A5. Drug Metab Dispos 39:947-51.
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 947-951
-
-
Xie, F.1
Zhou, X.2
Genter, M.B.3
|