Idiosyncratic NSAID drug induced oxidative stress

Chemico-Biological Interactions

Volumn 142, Issue 1-2, 2002, Pages 25-41

  Galati, Giuseppe ^a   Tafazoli, Shahrzad ^b   Sabzevari, Omid ^c   Chan, Tom S ^b   O'Brien, Peter J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Idiosyncratic drug reactions; NSAIDs; Oxidative stress; Prooxidant

Indexed keywords

4 AMINOPHENAZONE; AMINOPHENAZONE; ASCORBIC ACID; DAPSONE; DICLOFENAC; DIPHENYLAMINE; DIPYRONE; FLUFENAMIC ACID; GLUTATHIONE; HYDROGEN PEROXIDE; INDOMETACIN; INDOMETACIN DERIVATIVE; MECLOFENAMIC ACID; MEFENAMIC ACID; N DESCHLOROBENZOYL INDOMETHACIN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXIDASE; PROCAINAMIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SULFADIAZINE; SULFADIMETHOXINE; SULFAFURAZOLE; SULFAMETHOXAZOLE; SULFANILAMIDE; SULFANILIC ACID; SULFAPHENAZOLE; SULFAPYRIDINE; TOLFENAMIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CATALYST; CELL LEVEL; CONTROLLED STUDY; DRUG METABOLISM; DRUG OXIDATION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASCORBIC ACID; FREE RADICALS; GASTROINTESTINAL DISEASES; GLUTATHIONE; HEPATOCYTES; LIVER; MALE; NAD; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0037058249     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(02)00052-2     Document Type: Article

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