Cataract-Causing Mutation of Human Connexin 46 Impairs Gap Junction, but Increases Hemichannel Function and Cell Death

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Ren, Qian ^a,b   Riquelme, Manuel A ^b   Xu, Ji ^b   Yan, Xiang ^a   Nicholson, Bruce J ^b   Gu, Sumin ^b   Jiang, Jean X ^b  

^a LANZHOU UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 46;

APOPTOSIS; ARTICLE; CATARACT; CELL SURFACE; CELL VIABILITY; CHANNEL GATING; CONTROLLED STUDY; GAP JUNCTION; GJA3 GENE; MISSENSE MUTATION; OXIDATIVE STRESS; PROTEIN DOMAIN; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CATARACT; CONNEXINS; DNA PRIMERS; GAP JUNCTIONS; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84883381230     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074732     Document Type: Article

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