Phosphorylation of connexin 50 by protein kinase A enhances gap junction and hemichannel function

Journal of Biological Chemistry

Volumn 286, Issue 19, 2011, Pages 16914-16928

  Liu, Jialu ^a   Ek Vitorin, Jose F ^b   Weintraub, Susan T ^a   Gu, Sumin ^a   Shi, Qian ^a   Burt, Janis M ^b   Jiang, Jean X ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CELL SURFACES; CONDUCTANCE STATE; DYE UPTAKE; GAP JUNCTION CHANNELS; GAP JUNCTIONS; IN-CHANNELS; IN-VIVO; JUNCTIONAL PLAQUES; LENS FIBERS; METABOLIC COUPLING; PHOSPHOPEPTIDES; PROTEIN KINASE A; SINGLE CHANNEL RECORDING;

AMINO ACIDS; CELL MEMBRANES; CHROMATOGRAPHIC ANALYSIS; MASS SPECTROMETRY; OPTICAL INSTRUMENTS; THIN LAYER CHROMATOGRAPHY;

PHOSPHORYLATION;

CONNEXIN 50; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAP JUNCTION PROTEIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CHICKEN; CONTROLLED STUDY; ENZYME ACTIVATION; GAP JUNCTION; GENE MUTATION; IMMUNOPRECIPITATION; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS; THIN LAYER CHROMATOGRAPHY;

ANIMALS; CELL MEMBRANE; CHICK EMBRYO; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CONNEXINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EYE PROTEINS; GAP JUNCTIONS; MASS SPECTROMETRY; PHOSPHOPEPTIDES; PHOSPHORYLATION; RECOMBINANT PROTEINS; SERINE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRYPSIN;

EID: 79955787349     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.218735     Document Type: Article

References (48)

1. Meşe, G., Richard, G., and White, T. W. (2007) J. Invest. Dermatol. 127, 2516-2524
2. Lampe, P. D., and Lau, A. F. (2004) Int. J. Biochem. Cell Biol. 36, 1171-1186
3. Solan, J. L., and Lampe, P. D. (2009) Biochem. J. 419, 261-272
4. Cruciani, V., and Mikalsen, S. O. (2002) Biol. Cell. 94, 433-443
5. Solan, J. L., and Lampe, P. D. (2005) Biochim. Biophys. Acta. 1711, 154-163
6. Gong, X., Cheng, C., and Xia, C. H. (2007) J. Membr. Biol. 218, 9-12
7. Jiang, J. X., and Goodenough, D. A. (1998) Eur. J. Biochem. 255, 37-44
8. Cheng, H. L., and Louis, C. F. (1999) Eur. J. Biochem. 263, 276-286
9. Cheng, H. L., and Louis, C. F. (2001) J. Membr. Biol. 181, 21-30
10. Yin, X., Jedrzejewski, P. T., and Jiang, J. X. (2000) J. Biol. Chem. 275, 6850-6856
11. Yin, X., Gu, S., and Jiang, J. X. (2001) J. Biol. Chem. 276, 34567-34572
12. Berthoud, V. M., Beyer, E. C., Kurata, W. E., Lau, A. F., and Lampe, P. D. (1997) Eur. J. Biochem. 244, 89-97
13. Shearer, D., Ens, W., Standing, K., and Valdimarsson, G. (2008) Invest. Ophthalmol. Vis. Sci. 49, 1553-1562
14. Wang, Z., and Schey, K. L. (2009) Exp. Eye. Res. 89, 898-904
15. Jiang, J. X., White, T. W., Goodenough, D. A., and Paul, D. L. (1994) Mol. Biol. Cell. 5, 363-373
16. Jiang, J. X. (2001) Methods Mol. Biol. 154, 159-174
17. Banks, E. A., Toloue, M. M., Shi, Q., Zhou, Z. J., Liu, J., Nicholson, B. J., and Jiang, J. X. (2009) J. Cell Sci. 122, 378-388
18. el-Fouly, M. H., Trosko, J. E., and Chang, C. C. (1987) Exp. Cell Res. 168, 422-430
19. Cherian, P. P., Siller-Jackson, A. J., Gu, S., Wang, X., Bonewald, L. F., Sprague, E., and Jiang, J. X. (2005) Mol. Biol. Cell. 16, 3100-3106
20. Daniels, G. M., and Amara, S. G. (1998) Methods Enzymol. 296, 307-318
21. Musil, L. S., and Goodenough, D. A. (1991) J. Cell Biol. 115, 1357-1374
22. Ek-Vitorin, J. F., King, T. J., Heyman, N. S., Lampe, P. D., and Burt, J. M. (2006) Circ. Res. 98, 1498-1505
23. Srinivas, M., Costa, M., Gao, Y., Fort, A., Fishman, G. I., and Spray, D. C. (1999) J. Physiol. 517, 673-689
24. Moreno, A. P., Chanson, M., Elenes, S., Anumonwo, J., Scerri, I., Gu, H., Taffet, S. M., and Delmar, M. (2002) Circ. Res. 90, 450-457
25. Xu, X., Berthoud, V. M., Beyer, E. C., and Ebihara, L. (2002) J. Membr. Biol. 186, 101-112
26. Shibayama, J., Gutiérrez, C., González, D., Kieken, F., Seki, A., Carrión, J. R., Sorgen, P. L., Taffet, S. M., Barrio, L. C., and Delmar, M. (2006) Biophys. J. 91, 4054-4063
27. Burghardt, R. C., Barhoumi, R., Sewall, T. C., and Bowen, J. A. (1995) J. Membr. Biol. 148, 243-253
28. Atkinson, M. M., Lampe, P. D., Lin, H. H., Kollander, R., Li, X. R., and Kiang, D. T. (1995) J. Cell Sci. 108, 3079-3090
29. Paulson, A. F., Lampe, P. D., Meyer, R. A., TenBroek, E., Atkinson, M. M., Walseth, T. F., and Johnson, R. G. (2000) J. Cell Sci. 113, 3037-3049
30. TenBroek, E. M., Lampe, P. D., Solan, J. L., Reynhout, J. K., and Johnson, R. G. (2001) J. Cell Biol. 155, 1307-1318
31. Shah, M. M., Martinez, A. M., and Fletcher, W. H. (2002) Mol. Cell Biochem. 238, 57-68
32. Mitropoulou, G., and Bruzzone, R. (2003) J. Neurosci. Res. 72, 147-157
33. Ouyang, X., Winbow, V. M., Patel, L. S., Burr, G. S., Mitchell, C. K., and O'Brien, J. (2005) Brain Res. Mol. Brain Res. 135, 1-11
34. Li, H., Chuang, A. Z., and O'Brien, J. (2009) J. Neurosci. 29, 15178-15186
35. Urschel, S., Höher, T., Schubert, T., Alev, C., Söhl, G., Wörsdörfer, P., Asahara, T., Dermietzel, R., Weiler, R., and Willecke, K. (2006) J. Biol. Chem. 281, 33163-33171
36. Stergiopoulos, K., Alvarado, J. L.,Mastroianni, M., Ek-Vitorin, J. F., Taffet, S. M., and Delmar, M. (1999) Circ. Res. 84, 1144-1155
37. Anumonwo, J. M., Taffet, S. M., Gu, H., Chanson, M., Moreno, A. P., and Delmar, M. (2001) Circ. Res. 88, 666-673
38. Ebihara, L., Xu, X., Oberti, C., Beyer, E. C., and Berthoud, V. M. (1999) Biophys. J. 76, 198-206
39. Tong, J. J., and Ebihara, L. (2006) Biophys. J. 91, 2142-2154
40. Donaldson, P. J., Dong, Y., Roos, M., Green, C., Goodenough, D. A., and Kistler, J. (1995) Am. J. Physiol. 269, C590-C600
41. Heyman, N. S., and Burt, J. M. (2008) Biophys. J. 94, 840-854
42. Goodenough, D. A., and Paul, D. L. (2003) Nat. Rev. Mol. Cell. Biol. 4, 285-294
43. Bao, L., Sachs, F., and Dahl, G. (2004) Am. J. Physiol. 287, C1389-C1395
44. White, T. W., Gao, Y., Li, L., Sellitto, C., and Srinivas, M. (2007) Invest. Ophthal. Vis. Sci. 48, 5630-5637
45. DeRosa, A. M., Meşe, G., Li, L., Sellitto, C., Brink, P. R., Gong, X., and White, T. W. (2009) Exp. Cell Res. 315, 1063-1075
46. Heyman, N. S., Kurjiaka, D. T., Ek Vitorin, J. F., and Burt, J. M. (2009) Am. J. Physiol. Heart Circ. Physiol. 297, H450-H459
47. Hur, K. C., and Louis, C. F. (1989) Biochim. Biophys. Acta. 1010, 56-63
48. Mathias, R. T., Kistler, J., and Donaldson, P. (2007) J. Membr. Biol. 216, 1-16