A mutant connexin50 with enhanced hemichannel function leads to cell death

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 12, 2009, Pages 5837-5845

  Minogue, Peter J ^a   Tong, Jun Jie ^b   Arora, Anita ^c,d   Russell Eggitt, Isabelle ^e   Hunt, David M ^c   Moore, Anthony T ^c,d,e   Ebihara, Lisa ^b   Beyer, Eric C ^a   Berthoud, Viviana M ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d MOORFIELDS EYE HOSPITAL   (United Kingdom)

^e GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CONNEXIN 50; GAP JUNCTION PROTEIN; RNA; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ECDYSTERONE; EYE PROTEIN; PONASTERONE A;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CONGENITAL CATARACT; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; FLOW CYTOMETRY; GAP JUNCTION; GENE; GENE SEQUENCE; GJA8 GENE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; VOLTAGE CLAMP; XENOPUS; ANIMAL; CATARACT; CELL JUNCTION; CULTURE TECHNIQUE; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; PATCH CLAMP; PATHOLOGY; PHYSIOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; XENOPUS LAEVIS;

ANIMALS; APOPTOSIS; CATARACT; CELL CULTURE TECHNIQUES; CHILD, PRESCHOOL; CONNEXINS; ECDYSTERONE; EYE PROTEINS; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GAP JUNCTIONS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMUNOBLOTTING; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; POLYMERASE CHAIN REACTION; TRANSFECTION; XENOPUS LAEVIS;

EID: 73349108083     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3759     Document Type: Article

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