메뉴 건너뛰기




Volumn 126, Issue 17, 2013, Pages 4026-4036

Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression

Author keywords

C EBP ; Endoplasmic reticulum stress; Gene suppression; IL 4 IL 13 signaling

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; GADD34 PROTEIN; INITIATION FACTOR 2ALPHA; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; MESSENGER RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84883294923     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.130757     Document Type: Article
Times cited : (24)

References (63)
  • 2
    • 0033869876 scopus 로고    scopus 로고
    • Translational control of C/ EBPalpha and C/EBPbeta isoform expression
    • Calkhoven, C. F., Mü ller, C. and Leutz, A. (2000). Translational control of C/ EBPalpha and C/EBPbeta isoform expression. Genes Dev. 14, 1920-1932.
    • (2000) Genes Dev. , vol.14 , pp. 1920-1932
    • Calkhoven, C.F.1    Müller, C.2    Leutz, A.3
  • 3
    • 84873662942 scopus 로고    scopus 로고
    • C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver
    • Chikka, M. R., McCabe, D. D., Tyra, H. M. and Rutkowski, D. T. (2013). C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver. J. Biol. Chem. 288, 4405-4415.
    • (2013) J. Biol. Chem. , vol.288 , pp. 4405-4415
    • Chikka, M.R.1    McCabe, D.D.2    Tyra, H.M.3    Rutkowski, D.T.4
  • 4
    • 84881187385 scopus 로고    scopus 로고
    • Allergy and Allergic Diseases: The New Mechanisms and Therapeutics
    • Totowa, NJ: Humana Press
    • Denburg, J. A. (1998). Allergy and Allergic Diseases: The New Mechanisms and Therapeutics, pp. 599. Totowa, NJ: Humana Press.
    • (1998) , pp. 599
    • Denburg, J.A.1
  • 5
    • 0025936177 scopus 로고
    • A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
    • Descombes, P. and Schibler, U. (1991). A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67, 569-579.
    • (1991) Cell , vol.67 , pp. 569-579
    • Descombes, P.1    Schibler, U.2
  • 7
    • 0029982183 scopus 로고    scopus 로고
    • Physical and functional association between GADD153 and CCAAT/enhancerbinding protein beta during cellular stress
    • Fawcett, T. W., Eastman, H. B., Martindale, J. L. and Holbrook, N. J. (1996). Physical and functional association between GADD153 and CCAAT/enhancerbinding protein beta during cellular stress. J. Biol. Chem. 271, 14285-14289.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14285-14289
    • Fawcett, T.W.1    Eastman, H.B.2    Martindale, J.L.3    Holbrook, N.J.4
  • 8
    • 0037073712 scopus 로고    scopus 로고
    • Activation of an unfolded protein response during differentiation of antibody-secreting B cells
    • Gass, J. N., Gifford, N. M. and Brewer, J. W. (2002). Activation of an unfolded protein response during differentiation of antibody-secreting B cells. J. Biol. Chem. 277, 49047-49054.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49047-49054
    • Gass, J.N.1    Gifford, N.M.2    Brewer, J.W.3
  • 9
    • 35548935675 scopus 로고    scopus 로고
    • The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells
    • Gass, J. N., Jiang, H. Y., Wek, R. C. and Brewer, J. W. (2008). The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells. Mol. Immunol. 45, 1035-1043.
    • (2008) Mol. Immunol. , vol.45 , pp. 1035-1043
    • Gass, J.N.1    Jiang, H.Y.2    Wek, R.C.3    Brewer, J.W.4
  • 10
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
    • Harding, H. P., Zhang, Y. and Ron, D. (1999). Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397, 271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 11
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding, H. P., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, M. and Ron, D. (2000). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6, 1099-1108.
    • (2000) Mol. Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 12
    • 0037393323 scopus 로고    scopus 로고
    • IL-13 receptors and signaling pathways: an evolving web
    • Hershey, G. K. K. (2003). IL-13 receptors and signaling pathways: an evolving web. J. Allergy Clin. Immunol. 111, 677-690, quiz 691.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , pp. 677-690
    • Hershey, G.K.K.1
  • 13
    • 34848862650 scopus 로고    scopus 로고
    • Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells
    • Hitchler, M. J., Wikainapakul, K., Yu, L., Powers, K., Attatippaholkun, W. and Domann, F. E. (2006). Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells. Epigenetics 1, 163-171.
    • (2006) Epigenetics , vol.1 , pp. 163-171
    • Hitchler, M.J.1    Wikainapakul, K.2    Yu, L.3    Powers, K.4    Attatippaholkun, W.5    Domann, F.E.6
  • 14
    • 80052272692 scopus 로고    scopus 로고
    • Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches? J
    • Holgate, S. T. (2011). Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches? J. Allergy Clin. Immunol. 128, 495-505.
    • (2011) Allergy Clin. Immunol. , vol.128 , pp. 495-505
    • Holgate, S.T.1
  • 15
    • 33745893809 scopus 로고    scopus 로고
    • Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
    • Hollien, J. and Weissman, J. S. (2006). Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 104-107.
    • (2006) Science , vol.313 , pp. 104-107
    • Hollien, J.1    Weissman, J.S.2
  • 16
    • 68549092781 scopus 로고    scopus 로고
    • Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
    • Hollien, J., Lin, J. H., Li, H., Stevens, N., Walter, P. and Weissman, J. S. (2009). Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J. Cell Biol. 186, 323-331.
    • (2009) J. Cell Biol. , vol.186 , pp. 323-331
    • Hollien, J.1    Lin, J.H.2    Li, H.3    Stevens, N.4    Walter, P.5    Weissman, J.S.6
  • 17
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil, G. S. (2010). Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140, 900-917.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 18
    • 78751556358 scopus 로고    scopus 로고
    • Control of NF-kB and inflammation by the unfolded protein response
    • Kitamura, M. (2011). Control of NF-kB and inflammation by the unfolded protein response. Int. Rev. Immunol. 30, 4-15.
    • (2011) Int. Rev. Immunol. , vol.30 , pp. 4-15
    • Kitamura, M.1
  • 19
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee, K., Tirasophon, W., Shen, X., Michalak, M., Prywes, R., Okada, T., Yoshida, H., Mori, K. and Kaufman, R. J. (2002). IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev. 16, 452-466.
    • (2002) Genes Dev. , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5    Okada, T.6    Yoshida, H.7    Mori, K.8    Kaufman, R.J.9
  • 20
    • 53049110778 scopus 로고    scopus 로고
    • Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the response to endoplasmic reticulum stress
    • Li, Y., Bevilacqua, E., Chiribau, C. B., Majumder, M., Wang, C., Croniger, C. M., Snider, M. D., Johnson, P. F. and Hatzoglou, M. (2008). Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during the response to endoplasmic reticulum stress. J. Biol. Chem. 283, 22443-22456.
    • (2008) J. Biol. Chem. , vol.283 , pp. 22443-22456
    • Li, Y.1    Bevilacqua, E.2    Chiribau, C.B.3    Majumder, M.4    Wang, C.5    Croniger, C.M.6    Snider, M.D.7    Johnson, P.F.8    Hatzoglou, M.9
  • 21
    • 70349905357 scopus 로고    scopus 로고
    • Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis
    • Li, G., Mongillo, M., Chin, K. T., Harding, H. P., Ron, D., Marks, A. R. and Tabas, I. (2009). Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. J. Cell Biol. 186, 783-792.
    • (2009) J. Cell Biol. , vol.186 , pp. 783-792
    • Li, G.1    Mongillo, M.2    Chin, K.T.3    Harding, H.P.4    Ron, D.5    Marks, A.R.6    Tabas, I.7
  • 22
    • 33847005465 scopus 로고    scopus 로고
    • A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation
    • Lopez, A. B., Wang, C., Huang, C. C., Yaman, I., Li, Y., Chakravarty, K., Johnson, P. F., Chiang, C. M., Snider, M. D., Wek, R. C. et al. (2007). A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation. Biochem. J. 402, 163-173.
    • (2007) Biochem. J. , vol.402 , pp. 163-173
    • Lopez, A.B.1    Wang, C.2    Huang, C.C.3    Yaman, I.4    Li, Y.5    Chakravarty, K.6    Johnson, P.F.7    Chiang, C.M.8    Snider, M.D.9    Wek, R.C.10
  • 23
    • 77951252041 scopus 로고    scopus 로고
    • Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response
    • Ma, Y., Shimizu, Y., Mann, M. J., Jin, Y. and Hendershot, L. M. (2010). Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response. Cell Stress Chaperones 15, 281-293. Makino, C., Sano, Y., Shinagawa, T., Millar, J. B. and Ishii, S. (2006). Sin1 binds to both ATF-2 and p38 and enhances ATF-2-dependent transcription in an SAPK signaling pathway. Genes Cells 11, 1239-1251.
    • (2010) Cell Stress Chaperones , vol.15 , pp. 281-293
    • Ma, Y.1    Shimizu, Y.2    Mann, M.J.3    Jin, Y.4    Hendershot, L.M.5
  • 24
    • 33750142818 scopus 로고    scopus 로고
    • Sin1 binds to both ATF-2 and p38 and enhances ATF-2-dependent transcription in an SAPK signaling pathway
    • Makino, C., Sano, Y., Shinagawa, T., Millar, J. B. and Ishii, S. (2006). Sin1 binds to both ATF-2 and p38 and enhances ATF-2-dependent transcription in an SAPK signaling pathway. Genes Cells 11, 1239-1251.
    • (2006) Genes Cells , vol.11 , pp. 1239-1251
    • Makino, C.1    Sano, Y.2    Shinagawa, T.3    Millar, J.B.4    Ishii, S.5
  • 27
    • 0036190875 scopus 로고    scopus 로고
    • PROMO: detection of known transcription regulatory elements using species-tailored searches
    • Messeguer, X., Escudero, R., Farré, D., Núnez,O.,Martýnez, J. and Alba', M. M. (2002). PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 18, 333-334.
    • (2002) Bioinformatics , vol.18 , pp. 333-334
    • Messeguer, X.1    Escudero, R.2    Farré, D.3    Núnez, O.4    Martýnez, J.5    Alba', M.M.6
  • 28
    • 77952126162 scopus 로고    scopus 로고
    • IL-13 and the IL-13 receptor as therapeutic targets for asthma and allergic disease
    • Mitchell, J., Dimov, V. and Townley, R. G. (2010). IL-13 and the IL-13 receptor as therapeutic targets for asthma and allergic disease. Curr. Opin. Investig. Drugs 11, 527-534.
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 527-534
    • Mitchell, J.1    Dimov, V.2    Townley, R.G.3
  • 29
    • 0027499295 scopus 로고
    • Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6
    • Nakajima, T., Kinoshita, S., Sasagawa, T., Sasaki, K., Naruto, M., Kishimoto, T. and Akira, S. (1993). Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 90, 2207-2211.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2207-2211
    • Nakajima, T.1    Kinoshita, S.2    Sasagawa, T.3    Sasaki, K.4    Naruto, M.5    Kishimoto, T.6    Akira, S.7
  • 30
    • 0035947778 scopus 로고    scopus 로고
    • Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
    • Novoa, I., Zeng, H., Harding, H. P. and Ron, D. (2001). Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153, 1011-1022.
    • (2001) J. Cell Biol. , vol.153 , pp. 1011-1022
    • Novoa, I.1    Zeng, H.2    Harding, H.P.3    Ron, D.4
  • 31
    • 0037416211 scopus 로고    scopus 로고
    • Stress-induced gene expression requires programmed recovery from translational repression
    • Novoa, I., Zhang, Y., Zeng, H., Jungreis, R., Harding, H. P. and Ron, D. (2003). Stress-induced gene expression requires programmed recovery from translational repression. EMBO J. 22, 1180-1187.
    • (2003) EMBO J. , vol.22 , pp. 1180-1187
    • Novoa, I.1    Zhang, Y.2    Zeng, H.3    Jungreis, R.4    Harding, H.P.5    Ron, D.6
  • 32
    • 17144417669 scopus 로고    scopus 로고
    • TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
    • Ohoka, N., Yoshii, S., Hattori, T., Onozaki, K. and Hayashi, H. (2005). TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J. 24, 1243-1255.
    • (2005) EMBO J. , vol.24 , pp. 1243-1255
    • Ohoka, N.1    Yoshii, S.2    Hattori, T.3    Onozaki, K.4    Hayashi, H.5
  • 33
    • 55749087379 scopus 로고    scopus 로고
    • FunNet: an integrative tool for exploring transcriptional interactions
    • Prifti, E., Zucker, J. D., Clement, K. and Henegar, C. (2008). FunNet: an integrative tool for exploring transcriptional interactions. Bioinformatics 24, 2636-2638. Rawlings, J. S., Rosler, K. M. and Harrison, D. A. (2004). The JAK/STAT signaling pathway. J. Cell Sci. 117, 1281-1283.
    • (2008) Bioinformatics , vol.24 , pp. 2636-2638
    • Prifti, E.1    Zucker, J.D.2    Clement, K.3    Henegar, C.4
  • 35
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron, D. and Habener, J. F. (1992). CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 6, 439-453.
    • (1992) Genes Dev. , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 36
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron, D. and Walter, P. (2007). Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519-529. Rothman, P. (1993). Interleukin 4 targeting of immunoglobulin heavy chain classswitch recombination. Res. Immunol. 144, 579-583.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 37
    • 0027138289 scopus 로고
    • Interleukin 4 targeting of immunoglobulin heavy chain classswitch recombination
    • Rothman, P. (1993). Interleukin 4 targeting of immunoglobulin heavy chain classswitch recombination. Res. Immunol. 144, 579-583.
    • (1993) Res. Immunol. , vol.144 , pp. 579-583
    • Rothman, P.1
  • 38
    • 77953153048 scopus 로고    scopus 로고
    • Regulation of basal cellular physiology by the homeostatic unfolded protein response
    • Rutkowski, D. T. and Hegde, R. S. (2010). Regulation of basal cellular physiology by the homeostatic unfolded protein response. J. Cell Biol. 189, 783-794.
    • (2010) J. Cell Biol. , vol.189 , pp. 783-794
    • Rutkowski, D.T.1    Hegde, R.S.2
  • 39
    • 35348827324 scopus 로고    scopus 로고
    • That which does not kill me makes me stronger: adapting to chronic ER stress
    • Rutkowski, D. T. and Kaufman, R. J. (2007). That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem. Sci. 32, 469-476.
    • (2007) Trends Biochem. Sci. , vol.32 , pp. 469-476
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 41
    • 57049111040 scopus 로고    scopus 로고
    • UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
    • Rutkowski, D. T., Wu, J., Back, S. H., Callaghan, M. U., Ferris, S. P., Iqbal, J., Clark, R., Miao, H., Hassler, J. R., Fornek, J. et al. (2008). UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Dev. Cell 15, 829-840.
    • (2008) Dev. Cell , vol.15 , pp. 829-840
    • Rutkowski, D.T.1    Wu, J.2    Back, S.H.3    Callaghan, M.U.4    Ferris, S.P.5    Iqbal, J.6    Clark, R.7    Miao, H.8    Hassler, J.R.9    Fornek, J.10
  • 43
    • 80053469048 scopus 로고    scopus 로고
    • Mechanisms and principles of N-linked protein glycosylation
    • Schwarz, F. and Aebi, M. (2011). Mechanisms and principles of N-linked protein glycosylation. Curr. Opin. Struct. Biol. 21, 576-582.
    • (2011) Curr. Opin. Struct. Biol. , vol.21 , pp. 576-582
    • Schwarz, F.1    Aebi, M.2
  • 44
    • 66349092815 scopus 로고    scopus 로고
    • Mechanisms and consequences of macrophage apoptosis in atherosclerosis
    • Seimon, T. and Tabas, I. (2009). Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J. Lipid Res. 50 Suppl, S382-S387.
    • (2009) J. Lipid Res. , vol.50
    • Seimon, T.1    Tabas, I.2
  • 45
    • 0031755020 scopus 로고    scopus 로고
    • Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
    • Shi, Y., Vattem, K. M., Sood, R., An, J., Liang, J., Stramm, L. and Wek, R. C. (1998). Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol. Cell Biol. 18, 7499-7509. Skinnider, B. F., Kapp, U. and Mak, T. W. (2002). The role of interleukin 13 in classical Hodgkin lymphoma. Leuk. Lymphoma 43, 1203-1210.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 7499-7509
    • Shi, Y.1    Vattem, K.M.2    Sood, R.3    An, J.4    Liang, J.5    Stramm, L.6    Wek, R.C.7
  • 46
    • 0035992266 scopus 로고    scopus 로고
    • The role of interleukin 13 in classical Hodgkin lymphoma
    • Skinnider, B. F., Kapp, U. and Mak, T. W. (2002). The role of interleukin 13 in classical Hodgkin lymphoma. Leuk. Lymphoma 43, 1203-1210.
    • (2002) Leuk. Lymphoma , vol.43 , pp. 1203-1210
    • Skinnider, B.F.1    Kapp, U.2    Mak, T.W.3
  • 47
    • 0033962298 scopus 로고    scopus 로고
    • A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha
    • Sood, R., Porter, A. C., Olsen, D. A., Cavener, D. R. and Wek, R. C. (2000). A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha. Genetics 154, 787-801.
    • (2000) Genetics , vol.154 , pp. 787-801
    • Sood, R.1    Porter, A.C.2    Olsen, D.A.3    Cavener, D.R.4    Wek, R.C.5
  • 48
    • 0030987656 scopus 로고    scopus 로고
    • An essential role for C/ EBPbeta in female reproduction
    • Sterneck, E., Tessarollo, L. and Johnson, P. F. (1997). An essential role for C/ EBPbeta in female reproduction. Genes Dev. 11, 2153-2162.
    • (1997) Genes Dev. , vol.11 , pp. 2153-2162
    • Sterneck, E.1    Tessarollo, L.2    Johnson, P.F.3
  • 49
    • 58049203872 scopus 로고    scopus 로고
    • C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
    • Su, N. and Kilberg, M. S. (2008). C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene. J. Biol. Chem. 283, 35106-35117.
    • (2008) J. Biol. Chem. , vol.283 , pp. 35106-35117
    • Su, N.1    Kilberg, M.S.2
  • 50
    • 0027186357 scopus 로고
    • Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain
    • Trautwein, C., Caelles, C., van der Geer, P., Hunter, T., Karin, M. and Chojkier, M. (1993). Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain. Nature 364, 544-547.
    • (1993) Nature 3 , vol.64 , pp. 544-547
    • Trautwein, C.1    Caelles, C.2    van der Geer, P.3    Hunter, T.4    Karin, M.5    Chojkier, M.6
  • 51
    • 79952073585 scopus 로고    scopus 로고
    • The CCAAT/ enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation
    • Tsukada, J., Yoshida, Y., Kominato, Y. and Auron, P. E. (2011). The CCAAT/ enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation. Cytokine 54, 6-19.
    • (2011) Cytokine , vol.54 , pp. 6-19
    • Tsukada, J.1    Yoshida, Y.2    Kominato, Y.3    Auron, P.E.4
  • 52
    • 0029928173 scopus 로고    scopus 로고
    • Stress-induced binding of the transcription factor CHOP to a novel DNA control element
    • Ubeda, M., Wang, X. Z., Zinszner, H., Wu, I., Habener, J. F. and Ron, D. (1996). Stress-induced binding of the transcription factor CHOP to a novel DNA control element. Mol. Biol. Cell 16, 1479-1489.
    • (1996) Mol. Biol. Cell , vol.16 , pp. 1479-1489
    • Ubeda, M.1    Wang, X.Z.2    Zinszner, H.3    Wu, I.4    Habener, J.F.5    Ron, D.6
  • 53
    • 0027155881 scopus 로고
    • C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements
    • Vallejo, M., Ron, D., Miller, C. P. and Habener, J. F. (1993). C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements. Proc. Natl. Acad. Sci. USA 90, 4679-4683.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4679-4683
    • Vallejo, M.1    Ron, D.2    Miller, C.P.3    Habener, J.F.4
  • 54
    • 0037332128 scopus 로고    scopus 로고
    • Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion
    • van Anken, E., Romijn, E. P., Maggioni, C., Mezghrani, A., Sitia, R., Braakman, I. and Heck, A. J. (2003). Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity 18, 243-253.
    • (2003) Immunity , vol.18 , pp. 243-253
    • van Anken, E.1    Romijn, E.P.2    Maggioni, C.3    Mezghrani, A.4    Sitia, R.5    Braakman, I.6    Heck, A.J.7
  • 56
    • 67749135249 scopus 로고    scopus 로고
    • The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
    • Wang, Y., Vera, L., Fischer, W. H. and Montminy, M. (2009). The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature 460, 534-537.
    • (2009) Nature 4 , vol.60 , pp. 534-537
    • Wang, Y.1    Vera, L.2    Fischer, W.H.3    Montminy, M.4
  • 57
    • 58749091674 scopus 로고    scopus 로고
    • Untangling the complex web of IL-4- and IL-13-mediated signaling pathways
    • Wills-Karp, M. and Finkelman, F. D. (2008). Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Sci. Signal. 1, pe55.
    • (2008) Sci. Signal. , vol.1
    • Wills-Karp, M.1    Finkelman, F.D.2
  • 60
    • 0037775352 scopus 로고    scopus 로고
    • IL-13 effector functions
    • Wynn, T. A. (2003). IL-13 effector functions. Annu. Rev. Immunol. 21, 425-456. Zahnow, C. A. (2009). CCAAT/enhancer-binding protein b: its role in breast cancer and associations with receptor tyrosine kinases. Expert Rev. Mol. Med. 11, e12.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 425-456
    • Wynn, T.A.1
  • 61
    • 65349107367 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein b: its role in breast cancer and associations with receptor tyrosine kinases
    • Zahnow, C. A. (2009). CCAAT/enhancer-binding protein b: its role in breast cancer and associations with receptor tyrosine kinases. Expert Rev. Mol. Med. 11, e12.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Zahnow, C.A.1
  • 62
    • 0032054744 scopus 로고    scopus 로고
    • CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
    • Zinszner, H., Kuroda, M., Wang, X., Batchvarova, N., Lightfoot, R. T., Remotti, H., Stevens, J. L. and Ron, D. (1998). CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 12, 982-995.
    • (1998) Genes Dev. , vol.12 , pp. 982-995
    • Zinszner, H.1    Kuroda, M.2    Wang, X.3    Batchvarova, N.4    Lightfoot, R.T.5    Remotti, H.6    Stevens, J.L.7    Ron, D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.