Sulfoximines: A neglected opportunity in medicinal chemistry

Angewandte Chemie - International Edition

Volumn 52, Issue 36, 2013, Pages 9399-9408

  Lücking, Ulrich ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

drug design; medicinal chemistry; pharmacophores; sulfoximines

Indexed keywords

DAILY ROUTINES; DRUG DESIGN; DRUG DISCOVERY; MEDICINAL CHEMISTRY; PHARMACOPHORES; SELECTED EXAMPLES; STRUCTURAL ELEMENTS; SULFOXIMINES;

FUNCTIONAL GROUPS;

PHARMACODYNAMICS;

S-CYCLOPROPYL-S-(4-((4-((2-HYDROXY-1-METHYLPROPYL)OXY)-5-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL)AMINO)PHENYL)SULFOXIMIDE; CYCLIN DEPENDENT KINASE INHIBITOR; METHIONINE SULFOXIMINE; PYRIMIDINE DERIVATIVE; S CYCLOPROPYL S (4 ((4 ((2 HYDROXY 1 METHYLPROPYL)OXY) 5 (TRIFLUOROMETHYL)PYRIMIDIN 2 YL)AMINO)PHENYL)SULFOXIMIDE; SULFOXIDE;

CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; HUMAN; MEDICINAL CHEMISTRY; PHARMACOPHORES; REVIEW; SULFOXIMINES;

DRUG DESIGN; MEDICINAL CHEMISTRY; PHARMACOPHORES; SULFOXIMINES;

CHEMISTRY, PHARMACEUTICAL; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; HUMANS; METHIONINE SULFOXIMINE; MOLECULAR STRUCTURE; PYRIMIDINES; SULFOXIDES;

EID: 84883259434     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201302209     Document Type: Review

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