Ethyl acetate fraction of Garcina epunctata induces apoptosis in human promyelocytic cells (HL-60) through the ROS generation and G0/G1 cell cycle arrest: A bioassay-guided approach

Environmental Toxicology and Pharmacology

Volumn 36, Issue 3, 2013, Pages 865-874

  Constant Anatole, Pieme ^a,b   Guru, Santoh Kumar ^b   Bathelemy, Ngamegni ^a,c   Jeanne, Ngogang ^a   Bhushan, Shashi ^b   Murayama, Tetsuya ^c   Saxena, Ajit Kumar ^b  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c YAMAGATA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Cytotoxicity; G. epunctata; HL 60 cells; Mitochondrial membrane potential; ROS

Indexed keywords

ANTIMITOTIC AGENT; CYTOTOXIC AGENT; GARCINA EPUNCTATA EXTRACT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BARK; CELL PROLIFERATION; CELL STRAIN HL 60; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; GARCINA EPUNCTATA; HUMAN; HUMAN CELL; MALE; MEDICINAL PLANT; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROSTATE CANCER;

2′,7′-DICHLORODIHYDROFLUORESCIN DIACETATE; 3-(4,5-DIMETHYLTHIAZOLE-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; APOPTOSIS; CYTOTOXICITY; DCFH(2)-DA; G. EPUNCTATA; HEX; HEX-ETOAC; HEXANE; HEXANE ETYL ACETATE; HL-60 CELLS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL MITOCHONDRIAL POTENTIAL; MMP; MTT; PI; PROPIDIUM IODIDE; RH-123; RHODAMINE-123; ROS;

ACETATES; APOPTOSIS; BIOLOGICAL ASSAY; BISBENZIMIDAZOLE; CELL CYCLE; COLORING AGENTS; DNA, NEOPLASM; G0 PHASE; G1 PHASE; GARCINIA; HL-60 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; REACTIVE OXYGEN SPECIES; SOLVENTS;

EID: 84883233753     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.07.015     Document Type: Article

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