Sulforaphane suppresses TNF-α-mediated activation of NF-κB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3

Cancer Letters

Volumn 274, Issue 1, 2009, Pages 132-142

  Moon, Dong Oh ^a   Kim, Mun Ock ^b   Kang, Sang Hyuck ^a   Choi, Yung Hyun ^c   Kim, Gi Young ^c  

^a Jeju National University   (South Korea)

^b Pusan National University   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Caspase 3; Nuclear transcription factor B; Reactive oxygen species; Sulforaphane; Tumor necrosis factor

Indexed keywords

CASPASE 3; CYCLIN D1; CYCLOOXYGENASE 2; GELATINASE B; GENE PRODUCT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SULFORAPHANE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; X LINKED INHIBITOR OF APOPTOSIS;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CELL PROLIFERATION; CELL TYPE; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL PROLIFERATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; I-KAPPA B PROTEINS; NEOPLASMS; NF-KAPPA B; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; THIOCYANATES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57749088548     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.09.013     Document Type: Article

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