-
1
-
-
8344271026
-
Production of recombinant protein therapeutics in cultivated mammalian cells
-
PMID:15529164
-
Wurm FM. Production of recombinant protein therapeutics in cultivated mammalian cells. Nat Biotechnol 2004; 22:1393-8; PMID:15529164; http://dx.doi.org/10.1038/nbt1026.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1393-1398
-
-
Wurm, F.M.1
-
2
-
-
75449098662
-
Guidelines to cell engineering for monoclonal antibody production
-
PMID:19853660
-
Rita C.A, Elisa Rodrigues M, Henriques M, Azeredo J, Oliveira R. Guidelines to cell engineering for monoclonal antibody production. Eur J Pharm Biopharm 2010; 74:127-38; PMID:19853660; http://dx.doi.org/10.1016/j.ejpb.2009.10.002.
-
(2010)
Eur J Pharm Biopharm
, vol.74
, pp. 127-138
-
-
Rita, C.A.1
Elisa Rodrigues, M.2
Henriques, M.3
Azeredo, J.4
Oliveira, R.5
-
3
-
-
0035080494
-
Size matters: Use of YACs, BACs and PACs in transgenic animals
-
PMID:11305364
-
Giraldo P, Montoliu L. Size matters: use of YACs, BACs and PACs in transgenic animals. Transgenic Res 2001; 10:83-103; PMID:11305364; http://dx.doi.org/10.1023/A:1008918913249.
-
(2001)
Transgenic Res
, vol.10
, pp. 83-103
-
-
Giraldo, P.1
Montoliu, L.2
-
4
-
-
84856389498
-
CHO cells in biotechnology for production of recombinant proteins: Current state and further potential
-
PMID:22159888
-
Kim JY, Kim YG, Lee GM. CHO cells in biotechnology for production of recombinant proteins: current state and further potential. Appl Microbiol Biotechnol 2012; 93:917-30; PMID:22159888; http://dx.doi.org/10.1007/s00253-011-3758-5.
-
(2012)
Appl Microbiol Biotechnol
, vol.93
, pp. 917-930
-
-
Kim, J.Y.1
Kim, Y.G.2
Lee, G.M.3
-
5
-
-
0032530174
-
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
-
PMID:9744862
-
Pikaart MJ, Recillas-Targa F, Felsenfeld G. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev 1998; 12:2852-62; PMID:9744862; http://dx.doi.org/10.1101/gad.12.18.2852.
-
(1998)
Genes Dev
, vol.12
, pp. 2852-2862
-
-
Pikaart, M.J.1
Recillas-Targa, F.2
Felsenfeld, G.3
-
6
-
-
34548348766
-
Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells
-
PMID:17676049
-
Girod PA, Nguyen DQ, Calabrese D, Puttini S, Grandjean M, Martinet D, et al. Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells. Nat Methods 2007; 4:747-53; PMID:17676049; http://dx.doi.org/10.1038/nmeth1076.
-
(2007)
Nat Methods
, vol.4
, pp. 747-753
-
-
Girod, P.A.1
Nguyen, D.Q.2
Calabrese, D.3
Puttini, S.4
Grandjean, M.5
Martinet, D.6
-
7
-
-
12444283327
-
Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochroma-tin-mediated silencing
-
PMID:12906852
-
Antoniou M, Harland L, Mustoe T, Williams S, Holdstock J, Yague E, et al. Transgenes encompassing dual-promoter CpG islands from the human TBP and HNRPA2B1 loci are resistant to heterochroma-tin-mediated silencing. Genomics 2003; 82:269-79; PMID:12906852; http://dx.doi.org/10.1016/S0888-7543(03)00107-1.
-
(2003)
Genomics
, vol.82
, pp. 269-279
-
-
Antoniou, M.1
Harland, L.2
Mustoe, T.3
Williams, S.4
Holdstock, J.5
Yague, E.6
-
8
-
-
12444276606
-
Identification of anti-repressor elements that confer high and stable protein production in mammalian cells
-
PMID:12679786
-
Kwaks TH, Barnett P, Hemrika W, Siersma T, Sewalt RG, Satijn DP, et al. Identification of anti-repressor elements that confer high and stable protein production in mammalian cells. Nat Biotechnol 2003; 21:553-8; PMID:12679786; http://dx.doi.org/10.1038/nbt814.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 553-558
-
-
Kwaks, T.H.1
Barnett, P.2
Hemrika, W.3
Siersma, T.4
Sewalt, R.G.5
Satijn, D.P.6
-
9
-
-
34147179033
-
An efficient and targeted gene integration system for high-level antibody expression
-
PMID:17350648
-
Huang Y, Li Y, Wang YG, Gu X, Wang Y, Shen BF. An efficient and targeted gene integration system for high-level antibody expression. J Immunol Methods 2007; 322:28-39; PMID:17350648; http://dx.doi.org/10.1016/j.jim.2007.01.022.
-
(2007)
J Immunol Methods
, vol.322
, pp. 28-39
-
-
Huang, Y.1
Li, Y.2
Wang, Y.G.3
Gu, X.4
Wang, Y.5
Shen, B.F.6
-
10
-
-
74749086258
-
Recombinant protein expression by targeting pre-selected chromosomal loci
-
PMID:20003421
-
Nehlsen K, Schucht R, da Gama-Norton L, Krömer W, Baer A, Cayli A, et al. Recombinant protein expression by targeting pre-selected chromosomal loci. BMC Biotechnol 2009; 9:100; PMID:20003421; http://dx.doi.org/10.1186/1472-6750-9-100.
-
(2009)
BMC Biotechnol
, vol.9
, pp. 100
-
-
Nehlsen, K.1
Schucht, R.2
da Gama-Norton, L.3
Krömer, W.4
Baer, A.5
Cayli, A.6
-
11
-
-
80051535219
-
Genome engineering with zinc-finger nucleases
-
PMID:21828278
-
Carroll D. Genome engineering with zinc-finger nucleases. Genetics 2011; 188:773-82; PMID:21828278; http://dx.doi.org/10.1534/genet-ics.111.131433.
-
(2011)
Genetics
, vol.188
, pp. 773-782
-
-
Carroll, D.1
-
12
-
-
79751503682
-
TALEs of genome targeting
-
PMID:21301438
-
Boch J. TALEs of genome targeting. Nat Biotechnol 2011; 29:135-6; PMID:21301438; http://dx.doi.org/10.1038/nbt.1767.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 135-136
-
-
Boch, J.1
-
13
-
-
0141891816
-
Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells
-
PMID:14579745
-
Montigny WJ, Phelps SF, Illenye S, Heintz NH. Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells. Biotechniques 2003; 35:796-807; PMID:14579745.
-
(2003)
Biotechniques
, vol.35
, pp. 796-807
-
-
Montigny, W.J.1
Phelps, S.F.2
Illenye, S.3
Heintz, N.H.4
-
14
-
-
79251594210
-
Recombineering BAC transgenes for protein tagging
-
PMID:20868752
-
Ciotta G, Hofemeister H, Maresca M, Fu J, Sarov M, Anastassiadis K, et al. Recombineering BAC transgenes for protein tagging. Methods 2011; 53:113-9; PMID:20868752; http://dx.doi.org/10.1016/j.ymeth.2010.09.003.
-
(2011)
Methods
, vol.53
, pp. 113-119
-
-
Ciotta, G.1
Hofemeister, H.2
Maresca, M.3
Fu, J.4
Sarov, M.5
Anastassiadis, K.6
-
15
-
-
0035487293
-
Recombineering: A powerful new tool for mouse functional genomics
-
PMID:11584293
-
Copeland NG, Jenkins NA, Court DL. Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2001; 2:769-79; PMID:11584293; http://dx.doi.org/10.1038/35093556.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 769-779
-
-
Copeland, N.G.1
Jenkins, N.A.2
Court, D.L.3
-
16
-
-
0031664853
-
A new logic for DNA engineering using recombination in Escherichia coli
-
PMID:9771703
-
Zhang Y, Buchholz F, Muyrers JP, Stewart AF. A new logic for DNA engineering using recombination in Escherichia coli. Nat Genet 1998; 20:123-8; PMID:9771703; http://dx.doi.org/10.1038/2417.
-
(1998)
Nat Genet
, vol.20
, pp. 123-128
-
-
Zhang, Y.1
Buchholz, F.2
Muyrers, J.P.3
Stewart, A.F.4
-
17
-
-
77950795886
-
Building a zoo of mice for genetic analyses: A comprehensive protocol for the rapid generation of BAC transgenic mice
-
PMID:20143345
-
Johansson T, Broll I, Frenz T, Hemmers S, Becher B, Zeilhofer HU, et al. Building a zoo of mice for genetic analyses: a comprehensive protocol for the rapid generation of BAC transgenic mice. Genesis 2010; 48:264-80; PMID:20143345.
-
(2010)
Genesis
, vol.48
, pp. 264-280
-
-
Johansson, T.1
Broll, I.2
Frenz, T.3
Hemmers, S.4
Becher, B.5
Zeilhofer, H.U.6
-
18
-
-
33750352462
-
Transcriptional regulatory elements in the human genome
-
PMID:16719718;
-
Maston GA, Evans SK, Green MR. Transcriptional regulatory elements in the human genome. Annu Rev Genomics Hum Genet 2006; 7:29-59; PMID:16719718; http://dx.doi.org/10.1146/annurev.genom.7.080505.115623.
-
(2006)
Annu Rev Genomics Hum Genet
, vol.7
, pp. 29-59
-
-
Maston, G.A.1
Evans, S.K.2
Green, M.R.3
-
19
-
-
0030842624
-
Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome
-
PMID:9306400
-
Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nat Biotechnol 1997; 15:859-65; PMID:9306400; http://dx.doi.org/10.1038/nbt0997-859.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 859-865
-
-
Yang, X.W.1
Model, P.2
Heintz, N.3
-
20
-
-
77954367689
-
BAC TG-EMBED: One-step method for high-level, copy-number-dependent, position-independent transgene expression
-
PMID:20385594
-
Bian Q, Belmont AS. BAC TG-EMBED: one-step method for high-level, copy-number-dependent, position-independent transgene expression. Nucleic Acids Res 2010; 38:e127; PMID:20385594; http://dx.doi.org/10.1093/nar/gkq178.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Bian, Q.1
Belmont, A.S.2
-
21
-
-
62349130284
-
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells
-
PMID:19144171
-
Blaas L, Musteanu M, Eferl R, Bauer A, Casanova E. Bacterial artificial chromosomes improve recombinant protein production in mammalian cells. BMC Biotechnol 2009; 9:3; PMID:19144171; http://dx.doi.org/10.1186/1472-6750-9-3.
-
(2009)
BMC Biotechnol
, vol.9
, pp. 3
-
-
Blaas, L.1
Musteanu, M.2
Eferl, R.3
Bauer, A.4
Casanova, E.5
-
22
-
-
84855955718
-
The use of bacterial artificial chromosomes for recombinant protein production in mammalian cell lines
-
PMID:22160921
-
Blaas L, Musteanu M, Grabner B, Eferl R, Bauer A, Casanova E. The use of bacterial artificial chromosomes for recombinant protein production in mammalian cell lines. Methods Mol Biol 2012; 824:581-93; PMID:22160921; http://dx.doi.org/10.1007/978-1-61779-433-9_31.
-
(2012)
Methods Mol Biol
, vol.824
, pp. 581-593
-
-
Blaas, L.1
Musteanu, M.2
Grabner, B.3
Eferl, R.4
Bauer, A.5
Casanova, E.6
-
23
-
-
84885937143
-
Exploration of BAC versus plasmid expression vectors in recombinant CHO cells
-
PMID:23081777
-
Mader A, Prewein B, Zboray K, Casanova E, Kunert R. Exploration of BAC versus plasmid expression vectors in recombinant CHO cells. Appl Microbiol Biotechnol 2012; PMID:23081777; http://dx.doi.org/10.1007/s00253-012-4498-x.
-
(2012)
Appl Microbiol Biotechnol
-
-
Mader, A.1
Prewein, B.2
Zboray, K.3
Casanova, E.4
Kunert, R.5
-
24
-
-
0030990991
-
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
-
PMID:9108056
-
Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 1997; 94:3789-94; PMID:9108056; http://dx.doi.org/10.1073/pnas.94.8.3789.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3789-3794
-
-
Zambrowicz, B.P.1
Imamoto, A.2
Fiering, S.3
Herzenberg, L.A.4
Kerr, W.G.5
Soriano, P.6
-
25
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
PMID:9916792
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999; 21:70-1; PMID:9916792; http://dx.doi.org/10.1038/5007.
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
26
-
-
70350539619
-
Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells
-
PMID:19575438
-
Omasa T, Cao Y, Park JY, Takagi Y, Kimura S, Yano H, et al. Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells. Biotechnol Bioeng 2009; 104:986-94; PMID:19575438; http://dx.doi.org/10.1002/bit.22463.
-
(2009)
Biotechnol Bioeng
, vol.104
, pp. 986-994
-
-
Omasa, T.1
Cao, Y.2
Park, J.Y.3
Takagi, Y.4
Kimura, S.5
Yano, H.6
-
27
-
-
79961191745
-
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
-
PMID:21804562
-
Xu X, Nagarajan H, Lewis NE, Pan S, Cai Z, Liu X, et al. The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line. Nat Biotechnol 2011; 29:735-41; PMID:21804562; http://dx.doi.org/10.1038/nbt.1932.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 735-741
-
-
Xu, X.1
Nagarajan, H.2
Lewis, N.E.3
Pan, S.4
Cai, Z.5
Liu, X.6
|