메뉴 건너뛰기




Volumn 36, Issue 8, 2013, Pages 1235-1240

Updated neurophysiology of itch

Author keywords

Itch sensitization; Neuropathic itch; Pruritogen; Spinal receptor

Indexed keywords

ACETYLCHOLINE; CHLOROQUINE; DYNORPHIN; ENDORPHIN; GASTRIN RELEASING PEPTIDE; INTERLEUKIN 31; KAPPA OPIATE RECEPTOR AGONIST; MESSENGER RNA; MU OPIATE RECEPTOR AGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALFURAFINE; NALOXONE; NALTREXONE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; SUBSTANCE P;

EID: 84883203408     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00435     Document Type: Article
Times cited : (27)

References (70)
  • 3
    • 0035155197 scopus 로고    scopus 로고
    • Spinothalamic lamina I neurons selectively sensitive to histamine: A central neural pathway for itch
    • Andrew D, Craig AD. Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch. Nat. Neurosci., 4, 72-77 (2001).
    • (2001) Nat. Neurosci. , vol.4 , pp. 72-77
    • Andrew, D.1    Craig, A.D.2
  • 7
    • 43749117724 scopus 로고    scopus 로고
    • Cowhage-evoked itch is mediated by a novel cysteine protease: A ligand of protease-activated receptors
    • Reddy VB, Iuga AO, Shimada SG, LaMotte RH, Lerner EA. Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors. J. Neurosci., 28, 4331-4335 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 4331-4335
    • Reddy, V.B.1    Iuga, A.O.2    Shimada, S.G.3    Lamotte, R.H.4    Lerner, E.A.5
  • 9
    • 66749104438 scopus 로고    scopus 로고
    • Impact of scratching on itch and sympathetic reflexes induced by cowhage (Mucuna pruriens) and histamine
    • Kosteletzky F, Namer B, Forster C, Handwerker HO. Impact of scratching on itch and sympathetic reflexes induced by cowhage (Mucuna pruriens) and histamine. Acta Derm. Venereol., 89, 271-277 (2009).
    • (2009) Acta Derm. Venereol. , vol.89 , pp. 271-277
    • Kosteletzky, F.1    Namer, B.2    Forster, C.3    Handwerker, H.O.4
  • 10
    • 66049086427 scopus 로고    scopus 로고
    • Similar itch and nociceptive sensations evoked by punctate cutaneous application of capsaicin, histamine and cowhage
    • Sikand P, Shimada SG, Green BG, LaMotte RH. Similar itch and nociceptive sensations evoked by punctate cutaneous application of capsaicin, histamine and cowhage. Pain, 144, 66-75 (2009).
    • (2009) Pain , vol.144 , pp. 66-75
    • Sikand, P.1    Shimada, S.G.2    Green, B.G.3    Lamotte, R.H.4
  • 11
    • 33750989918 scopus 로고    scopus 로고
    • Changes in pain behavior induced by formalin, substance P, glutamate and pro-inflammatory cytokines in immobilization-induced stress mouse model
    • Seo YJ, Kwon MS, Shim EJ, Park SH, Choi OS, Suh HW. Changes in pain behavior induced by formalin, substance P, glutamate and pro-inflammatory cytokines in immobilization-induced stress mouse model. Brain Res. Bull., 71, 279-286 (2006).
    • (2006) Brain Res. Bull. , vol.71 , pp. 279-286
    • Seo, Y.J.1    Kwon, M.S.2    Shim, E.J.3    Park, S.H.4    Choi, O.S.5    Suh, H.W.6
  • 12
    • 53349177794 scopus 로고    scopus 로고
    • Behavioral differentiation between itch and pain in mouse
    • Shimada SG, LaMotte RH. Behavioral differentiation between itch and pain in mouse. Pain, 139, 681-687 (2008).
    • (2008) Pain , vol.139 , pp. 681-687
    • Shimada, S.G.1    Lamotte, R.H.2
  • 13
    • 84878011869 scopus 로고    scopus 로고
    • Mechanically evoked itch in humans
    • Fukuoka M, Miyachi Y, Ikoma A. Mechanically evoked itch in humans. Pain, 154, 897-904 (2013).
    • (2013) Pain , vol.154 , pp. 897-904
    • Fukuoka, M.1    Miyachi, Y.2    Ikoma, A.3
  • 14
    • 77949541373 scopus 로고    scopus 로고
    • The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation
    • Cowden JM, Zhang M, Dunford PJ, Thurmond RL. The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation. J. Invest. Dermatol., 130, 1023-1033 (2010).
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 1023-1033
    • Cowden, J.M.1    Zhang, M.2    Dunford, P.J.3    Thurmond, R.L.4
  • 16
    • 0036178653 scopus 로고    scopus 로고
    • Itch - Mediators and mechanisms
    • Schmelz M. Itch - mediators and mechanisms. J. Dermatol. Sci., 28, 91-96 (2002).
    • (2002) J. Dermatol. Sci. , vol.28 , pp. 91-96
    • Schmelz, M.1
  • 18
    • 0029565558 scopus 로고
    • Acetylcholine induces different cutaneous sensations in atopic and non-atopic subjects
    • Vogelsang M, Heyer G, Hornstein OP. Acetylcholine induces different cutaneous sensations in atopic and non-atopic subjects. Acta Derm. Venereol., 75, 434-436 (1995).
    • (1995) Acta Derm. Venereol. , vol.75 , pp. 434-436
    • Vogelsang, M.1    Heyer, G.2    Hornstein, O.P.3
  • 20
    • 0023892621 scopus 로고
    • Itching after epidural and spinal opiates
    • Ballantyne JC, Loach AB, Carr DB. Itching after epidural and spinal opiates. Pain, 33, 149-160 (1988).
    • (1988) Pain , vol.33 , pp. 149-160
    • Ballantyne, J.C.1    Loach, A.B.2    Carr, D.B.3
  • 21
    • 77952781302 scopus 로고    scopus 로고
    • Efficacy of intrathecal morphine with epidural ropivacaine infusion for postcesarean analgesia
    • Mikuni I, Hirai H, Toyama Y, Takahata O, Iwasaki H. Efficacy of intrathecal morphine with epidural ropivacaine infusion for postcesarean analgesia. J. Clin. Anesth., 22, 268-273 (2010).
    • (2010) J. Clin. Anesth. , vol.22 , pp. 268-273
    • Mikuni, I.1    Hirai, H.2    Toyama, Y.3    Takahata, O.4    Iwasaki, H.5
  • 23
    • 1642541866 scopus 로고    scopus 로고
    • Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: An in vivo microdialysis study in human skin
    • Blunk JA, Schmelz M, Zeck S, Skov P, Likar R, Koppert W. Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: an in vivo microdialysis study in human skin. Anesth. Analg., 98, 364-370 (2004).
    • (2004) Anesth. Analg. , vol.98 , pp. 364-370
    • Blunk, J.A.1    Schmelz, M.2    Zeck, S.3    Skov, P.4    Likar, R.5    Koppert, W.6
  • 24
    • 0020571204 scopus 로고
    • Mechanism of action of antipruritic drugs
    • Krause L, Shuster S. Mechanism of action of antipruritic drugs. Br. Med. J. (Clin. Res. Ed.), 287, 1199-1200 (1983).
    • (1983) Br. Med. J. (Clin. Res. Ed.) , vol.287 , pp. 1199-1200
    • Krause, L.1    Shuster, S.2
  • 28
    • 0027272313 scopus 로고
    • The medullary dorsal horn. A site of action of morphine in producing facial scratching in monkeys
    • Thomas DA, Williams GM, Iwata K, Kenshalo DR Jr, Dubner R. The medullary dorsal horn. A site of action of morphine in producing facial scratching in monkeys. Anesthesiology, 79, 548-554 (1993).
    • (1993) Anesthesiology , vol.79 , pp. 548-554
    • Thomas, D.A.1    Williams, G.M.2    Iwata, K.3    Kenshalo Jr., D.R.4    Dubner, R.5
  • 29
    • 0030775961 scopus 로고    scopus 로고
    • Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis
    • Heyer G, Dotzer M, Diepgen TL, Handwerker HO. Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis. Pain, 73, 239-243 (1997).
    • (1997) Pain , vol.73 , pp. 239-243
    • Heyer, G.1    Dotzer, M.2    Diepgen, T.L.3    Handwerker, H.O.4
  • 31
    • 27744535986 scopus 로고    scopus 로고
    • The pruritus of cholestasis
    • Bergasa NV. The pruritus of cholestasis. J. Hepatol., 43, 1078-1088 (2005).
    • (2005) J. Hepatol. , vol.43 , pp. 1078-1088
    • Bergasa, N.V.1
  • 32
    • 77956719480 scopus 로고    scopus 로고
    • Antipruritic treatment with systemic μ-opioid receptor antagonists: A review
    • Phan NQ, Bernhard JD, Luger TA, Ständer S. Antipruritic treatment with systemic μ-opioid receptor antagonists: a review. J. Am. Acad. Dermatol., 63, 680-688 (2010).
    • (2010) J. Am. Acad. Dermatol. , vol.63 , pp. 680-688
    • Phan, N.Q.1    Bernhard, J.D.2    Luger, T.A.3    Ständer, S.4
  • 33
    • 0042666912 scopus 로고    scopus 로고
    • Pain as a complication of use of opiate antagonists for symptom control in cholestasis
    • McRae CA, Prince MI, Hudson M, Day CP, James OF, Jones DE. Pain as a complication of use of opiate antagonists for symptom control in cholestasis. Gastroenterology, 125, 591-596 (2003).
    • (2003) Gastroenterology , vol.125 , pp. 591-596
    • McRae, C.A.1    Prince, M.I.2    Hudson, M.3    Day, C.P.4    James, O.F.5    Jones, D.E.6
  • 34
    • 58849139249 scopus 로고    scopus 로고
    • Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates
    • Ko MC, Husbands SM. Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates. J. Pharmacol. Exp. Ther., 328, 193-200 (2009).
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , pp. 193-200
    • Ko, M.C.1    Husbands, S.M.2
  • 37
    • 77950267997 scopus 로고    scopus 로고
    • Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: A Phase III, randomized, double-blind, placebo-controlled study
    • Kumagai H, Ebata T, Takamori K, Muramatsu T, Nakamoto H, Suzuki H. Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study. Nephrol. Dial. Transplant., 25, 1251-1257 (2010).
    • (2010) Nephrol. Dial. Transplant. , vol.25 , pp. 1251-1257
    • Kumagai, H.1    Ebata, T.2    Takamori, K.3    Muramatsu, T.4    Nakamoto, H.5    Suzuki, H.6
  • 38
    • 34547726181 scopus 로고    scopus 로고
    • A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord
    • Sun YG, Chen ZF. A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature, 448, 700-703 (2007).
    • (2007) Nature , vol.448 , pp. 700-703
    • Sun, Y.G.1    Chen, Z.F.2
  • 41
    • 0035822998 scopus 로고    scopus 로고
    • A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons
    • Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell, 106, 619-632 (2001).
    • (2001) Cell , vol.106 , pp. 619-632
    • Dong, X.1    Han, S.2    Zylka, M.J.3    Simon, M.I.4    Anderson, D.J.5
  • 42
    • 0043192823 scopus 로고    scopus 로고
    • Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family
    • Zylka MJ, Dong X, Southwell AL, Anderson DJ. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc. Natl. Acad. Sci. U.S.A., 100, 10043-10048 (2003).
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 10043-10048
    • Zylka, M.J.1    Dong, X.2    Southwell, A.L.3    Anderson, D.J.4
  • 43
    • 74949142941 scopus 로고    scopus 로고
    • Pain: Itch without pain-A labeled line for itch sensation?
    • Handwerker HO, Schmelz M. Pain: itch without pain-a labeled line for itch sensation? Nat. Rev. Neurol., 5, 640-641 (2009).
    • (2009) Nat. Rev. Neurol. , vol.5 , pp. 640-641
    • Handwerker, H.O.1    Schmelz, M.2
  • 45
    • 0032161858 scopus 로고    scopus 로고
    • Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice
    • Andoh T, Nagasawa T, Satoh M, Kuraishi Y. Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J. Pharmacol. Exp. Ther., 286, 1140-1145 (1998).
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 1140-1145
    • Andoh, T.1    Nagasawa, T.2    Satoh, M.3    Kuraishi, Y.4
  • 46
    • 0035678082 scopus 로고    scopus 로고
    • Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice
    • Andoh T, Katsube N, Maruyama M, Kuraishi Y. Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice. J. Invest. Dermatol., 117, 1621-1626 (2001).
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1621-1626
    • Andoh, T.1    Katsube, N.2    Maruyama, M.3    Kuraishi, Y.4
  • 48
    • 0023502648 scopus 로고
    • Occurrence of substance P, vasoactive intestinal peptide, and calcitonin gene-related peptide in dermographism and cold urticaria
    • Wallengren J, Möller H, Ekman R. Occurrence of substance P, vasoactive intestinal peptide, and calcitonin gene-related peptide in dermographism and cold urticaria. Arch. Dermatol. Res., 279, 512-515 (1987).
    • (1987) Arch. Dermatol. Res. , vol.279 , pp. 512-515
    • Wallengren, J.1    Möller, H.2    Ekman, R.3
  • 49
    • 0030777781 scopus 로고    scopus 로고
    • Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis
    • Chan J, Smoller BR, Raychauduri SP, Jiang WY, Farber EM, Chan C. Intraepidermal nerve fiber expression of calcitonin gene-related peptide, vasoactive intestinal peptide and substance P in psoriasis. Arch. Dermatol. Res., 289, 611-616 (1997).
    • (1997) Arch. Dermatol. Res. , vol.289 , pp. 611-616
    • Chan, J.1    Smoller, B.R.2    Raychauduri, S.P.3    Jiang, W.Y.4    Farber, E.M.5    Chan, C.6
  • 50
  • 52
    • 33751220216 scopus 로고    scopus 로고
    • How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom
    • Costa SK, Starr A, Hyslop S, Gilmore D, Brain SD. How important are NK1 receptors for influencing microvascular inflammation and itch in the skin? Studies using Phoneutria nigriventer venom. Vascul. Pharmacol., 45, 209-214 (2006).
    • (2006) Vascul. Pharmacol. , vol.45 , pp. 209-214
    • Costa, S.K.1    Starr, A.2    Hyslop, S.3    Gilmore, D.4    Brain, S.D.5
  • 53
    • 70349626195 scopus 로고    scopus 로고
    • Aprepitant as an antipruritic agent?
    • Duval A, Dubertret L. Aprepitant as an antipruritic agent? N. Engl. J. Med., 361, 1415-1416 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1415-1416
    • Duval, A.1    Dubertret, L.2
  • 54
    • 77956193969 scopus 로고    scopus 로고
    • Targeting the neurokinin receptor 1 with aprepitant: A novel antipruritic strategy
    • Ständer S, Siepmann D, Herrgott I, Sunderkötter C, Luger TA. Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy. PLoS ONE, 5, e10968 (2010).
    • (2010) PLoS ONE , vol.5
    • Ständer, S.1    Siepmann, D.2    Herrgott, I.3    Sunderkötter, C.4    Luger, T.A.5
  • 55
    • 64949130758 scopus 로고    scopus 로고
    • Plasticity of NMDA receptor NR2B subunit in memory and chronic pain
    • Zhuo M. Plasticity of NMDA receptor NR2B subunit in memory and chronic pain. Mol. Brain, 2, 4 (2009).
    • (2009) Mol. Brain , vol.2 , pp. 4
    • Zhuo, M.1
  • 56
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • Woolf CJ, Salter MW. Neuronal plasticity: increasing the gain in pain. Science, 288, 1765-1769 (2000).
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 57
    • 0242492118 scopus 로고    scopus 로고
    • Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis
    • Ikoma A, Rukwied R, Ständer S, Steinhoff M, Miyachi Y, Schmelz M. Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis. Arch. Dermatol., 139, 1455-1458 (2003).
    • (2003) Arch. Dermatol. , vol.139 , pp. 1455-1458
    • Ikoma, A.1    Rukwied, R.2    Ständer, S.3    Steinhoff, M.4    Miyachi, Y.5    Schmelz, M.6
  • 58
    • 0031765661 scopus 로고    scopus 로고
    • Increased intraepithelial innervation in women with vulvar vestibulitis syndrome
    • Bohm-Starke N, Hilliges M, Falconer C, Rylander E. Increased intraepithelial innervation in women with vulvar vestibulitis syndrome. Gynecol. Obstet. Invest., 46, 256-260 (1998).
    • (1998) Gynecol. Obstet. Invest. , vol.46 , pp. 256-260
    • Bohm-Starke, N.1    Hilliges, M.2    Falconer, C.3    Rylander, E.4
  • 59
    • 0033810051 scopus 로고    scopus 로고
    • Increase in NGF content and nerve fiber sprouting in human allergic contact eczema
    • Kinkelin I, Mötzing S, Koltenzenburg M, Bröcker EB. Increase in NGF content and nerve fiber sprouting in human allergic contact eczema. Cell Tissue Res., 302, 31-37 (2000).
    • (2000) Cell Tissue Res. , vol.302 , pp. 31-37
    • Kinkelin, I.1    Mötzing, S.2    Koltenzenburg, M.3    Bröcker, E.B.4
  • 60
    • 0344414304 scopus 로고    scopus 로고
    • Cutaneous nerves in atopic dermatitis. A histological, immunohistochemical and electron microscopic study
    • Urashima R, Mihara M. Cutaneous nerves in atopic dermatitis. A histological, immunohistochemical and electron microscopic study. Virchows Arch., 432, 363-370 (1998).
    • (1998) Virchows Arch. , vol.432 , pp. 363-370
    • Urashima, R.1    Mihara, M.2
  • 62
    • 0842347345 scopus 로고    scopus 로고
    • Painful stimuli evoke itch in patients with chronic pruritus: Central sensitization for itch
    • Ikoma A, Fartasch M, Heyer G, Miyachi Y, Handwerker H, Schmelz M. Painful stimuli evoke itch in patients with chronic pruritus: central sensitization for itch. Neurology, 62, 212-217 (2004).
    • (2004) Neurology , vol.62 , pp. 212-217
    • Ikoma, A.1    Fartasch, M.2    Heyer, G.3    Miyachi, Y.4    Handwerker, H.5    Schmelz, M.6
  • 64
    • 70349481938 scopus 로고    scopus 로고
    • Treatment of neuropathic pain: An overview of recent guidelines
    • O'Connor AB, Dworkin RH. Treatment of neuropathic pain: an overview of recent guidelines. Am. J. Med., 122 (Suppl.), S22-S32 (2009).
    • (2009) Am. J. Med. , vol.122 , Issue.SUPPL.
    • O'Connor, A.B.1    Dworkin, R.H.2
  • 65
    • 0029975930 scopus 로고    scopus 로고
    • The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel
    • Gee NS, Brown JP, Dissanayake VU, Offord J, Thurlow R, Woodruff GN. The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J. Biol. Chem., 271, 5768-5776 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 5768-5776
    • Gee, N.S.1    Brown, J.P.2    Dissanayake, V.U.3    Offord, J.4    Thurlow, R.5    Woodruff, G.N.6
  • 66
    • 33745947782 scopus 로고    scopus 로고
    • Mechanisms of the antinociceptive action of gabapentin
    • Cheng JK, Chiou LC. Mechanisms of the antinociceptive action of gabapentin. J. Pharmacol. Sci., 100, 471-486 (2006).
    • (2006) J. Pharmacol. Sci. , vol.100 , pp. 471-486
    • Cheng, J.K.1    Chiou, L.C.2
  • 67
    • 0038377273 scopus 로고    scopus 로고
    • The role of gabapentin in treating diseases with cutaneous manifestations and pain
    • Scheinfeld N. The role of gabapentin in treating diseases with cutaneous manifestations and pain. Int. J. Dermatol., 42, 491-495 (2003).
    • (2003) Int. J. Dermatol. , vol.42 , pp. 491-495
    • Scheinfeld, N.1
  • 68
    • 2342503258 scopus 로고    scopus 로고
    • Brachioradial pruritus: Response to treatment with gabapentin
    • Winhoven SM, Coulson IH, Bottomley WW. Brachioradial pruritus: response to treatment with gabapentin. Br. J. Dermatol., 150, 786-787 (2004).
    • (2004) Br. J. Dermatol. , vol.150 , pp. 786-787
    • Winhoven, S.M.1    Coulson, I.H.2    Bottomley, W.W.3
  • 69
    • 29244477994 scopus 로고    scopus 로고
    • Efficacy of gabapentin in the management of pruritus of unknown origin
    • Yesudian PD, Wilson NJ. Efficacy of gabapentin in the management of pruritus of unknown origin. Arch. Dermatol., 141, 1507-1509 (2005).
    • (2005) Arch. Dermatol. , vol.141 , pp. 1507-1509
    • Yesudian, P.D.1    Wilson, N.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.