A novel phenoxy thiophene sulphonamide molecule protects against glutamate evoked oxidative injury in a neuronal cell model

BMC Neuroscience

Volumn 14, Issue , 2013, Pages

  Gliyazova, Nailya S ^a   Huh, Eun Y ^b   Ibeanu, Gordon C ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; ERK3; Excitotoxicity; Glutamate; HT 22; Neurodegenerative disease; Neuroprotection; Oxidative stress; Phenoxy thiophene; Small molecule

Indexed keywords

ACRIDINE ORANGE; APOPTOSIS INDUCING FACTOR; B 355252; ETHIDIUM BROMIDE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 6; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM CELL LEVEL; CELL ASSAY; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME PHOSPHORYLATION; EXCITOTOXICITY; FLUORESCENCE MICROSCOPY; GLUTATHIONE METABOLISM; HIPPOCAMPUS; LONG TERM EXPOSURE; MOLECULAR LIBRARY; NERVE FIBER GROWTH; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PHASE CONTRAST MICROSCOPY; PRIMARY CULTURE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STAINING;

ANIMALS; CELL LINE; CELL SURVIVAL; EXCITATORY AMINO ACIDS; GLUTAMIC ACID; IMMUNOBLOTTING; MICE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; SULFONAMIDES; THIOPHENES;

EID: 84883202356     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-14-93     Document Type: Article

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