Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

Cell Death and Differentiation

Volumn 18, Issue 2, 2011, Pages 282-292

  Tobaben, S ^a   Grohm, J ^a   Seiler, A ^b   Conrad, M ^b,d   Plesnila, N ^c   Culmsee, C ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

apoptosis; apoptosis inducing factor; glutamate; lipid peroxidation; mitochondria; neuronal cell death; reactive oxygen species

Indexed keywords

APOPTOSIS INDUCING FACTOR; CALCIUM CHANNEL; GLUTAMIC ACID; GLUTATHIONE; LIPID PEROXIDE; LIPOXYGENASE; PROTEIN BID; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL DAMAGE; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; FRAGMENTATION REACTION; HIPPOCAMPUS; LIPID PEROXIDATION; MITOCHONDRIAL DAMAGE; MOLECULAR MECHANICS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CELL LINE, TRANSFORMED; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; LIPOXYGENASE INHIBITORS; LIPOXYGENASES; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 78651306433     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.92     Document Type: Article

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