Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex

Neurobiology of Disease

Volumn 28, Issue 2, 2007, Pages 184-196

  Zeng, Ling Hui ^a   Ouyang, Yannan ^a   Gazit, Vered ^a   Cirrito, John R ^a   Jansen, Laura A ^a   Ess, Kevin C ^a   Yamada, Kelvin A ^a   Wozniak, David F ^a   Holtzman, David M ^a   Gutmann, David H ^a   Wong, Michael ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocyte; Epilepsy; Excitotoxicity; Glia; Glutamate transporter; Learning; Long term potentiation; Microdialysis; Seizure

Indexed keywords

GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

AMINO ACID BRAIN LEVEL; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN DEPTH STIMULATION; BRAIN NERVE CELL; BRAIN SLICE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE PREDISPOSITION; EXCITOTOXICITY; HIPPOCAMPUS; LEARNING DISORDER; LONG TERM POTENTIATION; MOUSE; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; TUBEROUS SCLEROSIS;

ANIMALS; ASTROCYTES; BRAIN; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID ANTAGONISTS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; HIPPOCAMPUS; HOMEOSTASIS; LEARNING DISORDERS; LONG-TERM POTENTIATION; MICE; MICE, KNOCKOUT; NEOCORTEX; NERVE DEGENERATION; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; SYNAPTIC TRANSMISSION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 35348950503     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2007.07.015     Document Type: Article

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