-
1
-
-
84868201754
-
From drug discovery to biomarker-driven clinical trials in lymphoma
-
Younes A, Berry DA, (2012) From drug discovery to biomarker-driven clinical trials in lymphoma. Nat Rev Clin Oncol 9: 543-53.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 543-553
-
-
Younes, A.1
Berry, D.A.2
-
2
-
-
9144227152
-
Antilymphoma effects of anti-HLA-DR and CD20 monoclonal antibodies (Lym-1 and Rituximab) on human lymphoma cells
-
Liu C, DeNardo G, Tobin E, DeNardo S, (2004) Antilymphoma effects of anti-HLA-DR and CD20 monoclonal antibodies (Lym-1 and Rituximab) on human lymphoma cells. Cancer Biother Radiopharm 19: 545-61.
-
(2004)
Cancer Biother Radiopharm
, vol.19
, pp. 545-561
-
-
Liu, C.1
DeNardo, G.2
Tobin, E.3
DeNardo, S.4
-
3
-
-
0033756330
-
Monoclonal Lym-1 antibody-targeted lysis of B lymphoma cells by neutrophils. Evidence for two mechanisms of FcgammaRII-dependent cytolysis
-
Ottonello L, Epstein AL, Mancini M, Amelotti M, Dapino P, et al. (2000) Monoclonal Lym-1 antibody-targeted lysis of B lymphoma cells by neutrophils. Evidence for two mechanisms of FcgammaRII-dependent cytolysis. J Leukoc Biol 68: 662-8.
-
(2000)
J Leukoc Biol
, vol.68
, pp. 662-668
-
-
Ottonello, L.1
Epstein, A.L.2
Mancini, M.3
Amelotti, M.4
Dapino, P.5
-
4
-
-
34547734419
-
Pharmacokinetic characterization in xenografted mice of a series of first-generation mimics for HLA-DR antibody, Lym-1, as carrier molecules to image and treat lymphoma
-
DeNardo GL, Natarajan A, Hok S, Perkins J, Cosman M, et al. (2007) Pharmacokinetic characterization in xenografted mice of a series of first-generation mimics for HLA-DR antibody, Lym-1, as carrier molecules to image and treat lymphoma. J Nucl Med 48: 1338-47.
-
(2007)
J Nucl Med
, vol.48
, pp. 1338-1347
-
-
DeNardo, G.L.1
Natarajan, A.2
Hok, S.3
Perkins, J.4
Cosman, M.5
-
5
-
-
34447538253
-
Lym-1-induced apoptosis of non-Hodgkin's lymphomas produces regression of transplanted tumors
-
Zhang N, Khawli LA, Hu P, Epstein AL, (2007) Lym-1-induced apoptosis of non-Hodgkin's lymphomas produces regression of transplanted tumors. Cancer Biother Radiopharm 22: 342-56.
-
(2007)
Cancer Biother Radiopharm
, vol.22
, pp. 342-356
-
-
Zhang, N.1
Khawli, L.A.2
Hu, P.3
Epstein, A.L.4
-
6
-
-
78650328444
-
Autophagy basics
-
Tanida I, (2011) Autophagy basics. Microbiol Immunol 55: 1-11.
-
(2011)
Microbiol Immunol
, vol.55
, pp. 1-11
-
-
Tanida, I.1
-
7
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E, (2010) Autophagy and metabolism. Science 330: 1344-8.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
8
-
-
33846244269
-
Role of autophagy in cancer: management of metabolic stress
-
Jin S, White E, (2007) Role of autophagy in cancer: management of metabolic stress. Autophagy 3: 28-31.
-
(2007)
Autophagy
, vol.3
, pp. 28-31
-
-
Jin, S.1
White, E.2
-
9
-
-
80052697287
-
The role of autophagy in cancer: therapeutic implications
-
Yang ZJ, Chee CE, Huang S, Sinicrope FA, (2011) The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther 10: 1533-41.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1533-1541
-
-
Yang, Z.J.1
Chee, C.E.2
Huang, S.3
Sinicrope, F.A.4
-
10
-
-
60449092595
-
Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells
-
Li J, Hou N, Faried A, Tsutsumi S, Takeuchi T, et al. (2009) Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann Surg Oncol 16: 761-71.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 761-771
-
-
Li, J.1
Hou, N.2
Faried, A.3
Tsutsumi, S.4
Takeuchi, T.5
-
11
-
-
67650885510
-
Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab
-
Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA, (2009) Autophagy facilitates the development of breast cancer resistance to the anti-HER2 monoclonal antibody trastuzumab. PLoS One 4: e6251.
-
(2009)
PLoS One
, vol.4
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
12
-
-
78649251524
-
Roles of autophagy in cetuximab-mediated cancer therapy against EGFR
-
Li X, Lu Y, Pan T, Fan Z, (2010) Roles of autophagy in cetuximab-mediated cancer therapy against EGFR. Autophagy 6: 1066-77.
-
(2010)
Autophagy
, vol.6
, pp. 1066-1077
-
-
Li, X.1
Lu, Y.2
Pan, T.3
Fan, Z.4
-
13
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D, Kimchi A, (2004) Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23: 2891-906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
14
-
-
37849028908
-
Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells
-
Yang YP, Liang ZQ, Gao B, Jia YL, Qin ZH, (2008) Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells. Acta Pharmacol Sin 29: 123-34.
-
(2008)
Acta Pharmacol Sin
, vol.29
, pp. 123-134
-
-
Yang, Y.P.1
Liang, Z.Q.2
Gao, B.3
Jia, Y.L.4
Qin, Z.H.5
-
15
-
-
77955038334
-
The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
-
Li X, Fan Z, (2010) The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res 70: 5942-52.
-
(2010)
Cancer Res
, vol.70
, pp. 5942-5952
-
-
Li, X.1
Fan, Z.2
-
16
-
-
84859778293
-
mTOR signaling in growth control and disease
-
Laplante M, Sabatini DM, (2012) mTOR signaling in growth control and disease. Cell 149: 274-93.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
17
-
-
84863654925
-
The role and regulation of mTOR in T-lymphocyte function
-
O'Brien TF, Zhong XP, (2012) The role and regulation of mTOR in T-lymphocyte function. Arch Immunol Ther Exp (Warsz) 60: 173-81.
-
(2012)
Arch Immunol Ther Exp (Warsz)
, vol.60
, pp. 173-181
-
-
O'Brien, T.F.1
Zhong, X.P.2
-
19
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D, (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18: 571-80.
-
(2011)
Cell Death Differ
, vol.18
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
20
-
-
78751655392
-
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
-
Zhou F, Yang Y, Xing D, (2011) Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 278: 403-13.
-
(2011)
FEBS J
, vol.278
, pp. 403-413
-
-
Zhou, F.1
Yang, Y.2
Xing, D.3
-
21
-
-
33846204370
-
UVRAG: a new player in autophagy and tumor cell growth
-
Liang C, Feng P, Ku B, Oh BH, Jung JU, (2007) UVRAG: a new player in autophagy and tumor cell growth. Autophagy 3: 69-71.
-
(2007)
Autophagy
, vol.3
, pp. 69-71
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Oh, B.H.4
Jung, J.U.5
-
22
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, et al. (2007) Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 117: 326-36.
-
(2007)
J Clin Invest
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
-
23
-
-
84862549609
-
Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium
-
Kumari S, Mehta SL, Li PA, (2012) Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium. PLoS One 7: e39382.
-
(2012)
PLoS One
, vol.7
-
-
Kumari, S.1
Mehta, S.L.2
Li, P.A.3
-
24
-
-
84866560614
-
A novel image-based cytometry method for autophagy detection in living cells
-
Chan LL, Shen D, Wilkinson AR, Patton W, Lai N, et al. (2012) A novel image-based cytometry method for autophagy detection in living cells. Autophagy 8: 1371-82.
-
(2012)
Autophagy
, vol.8
, pp. 1371-1382
-
-
Chan, L.L.1
Shen, D.2
Wilkinson, A.R.3
Patton, W.4
Lai, N.5
-
25
-
-
0030158334
-
Antibody-dependent cell-mediated cytotoxicity against orbital target cells in thyroid-associated ophthalmopathy and related disorders; close relationship between serum cytotoxic antibodies and parameters of eye muscle dysfunction
-
Barsouk A, Peele KA, Kiljanski J, Stolarski C, Nebes V, et al. (1996) Antibody-dependent cell-mediated cytotoxicity against orbital target cells in thyroid-associated ophthalmopathy and related disorders; close relationship between serum cytotoxic antibodies and parameters of eye muscle dysfunction. J Endocrinol Invest 19: 334-41.
-
(1996)
J Endocrinol Invest
, vol.19
, pp. 334-341
-
-
Barsouk, A.1
Peele, K.A.2
Kiljanski, J.3
Stolarski, C.4
Nebes, V.5
-
26
-
-
77952565721
-
Bortezomib modulates surface CD20 in B-cell malignancies and affects rituximab-mediated complement-dependent cytotoxicity
-
Bil J, Winiarska M, Nowis D, Bojarczuk K, Dabrowska-Iwanicka A, et al. (2010) Bortezomib modulates surface CD20 in B-cell malignancies and affects rituximab-mediated complement-dependent cytotoxicity. Blood 115: 3745-55.
-
(2010)
Blood
, vol.115
, pp. 3745-3755
-
-
Bil, J.1
Winiarska, M.2
Nowis, D.3
Bojarczuk, K.4
Dabrowska-Iwanicka, A.5
-
27
-
-
33947586193
-
Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus)
-
Liu C, Yu K, Shi X, Wang J, Lam PK, et al. (2007) Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus). Aquat Toxicol 82: 135-43.
-
(2007)
Aquat Toxicol
, vol.82
, pp. 135-143
-
-
Liu, C.1
Yu, K.2
Shi, X.3
Wang, J.4
Lam, P.K.5
-
28
-
-
34047252379
-
Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway
-
Liu Y, Zhang S, Cai Y, (2007) Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway. Toxicol In Vitro. 21: 677-84.
-
(2007)
Toxicol In Vitro
, vol.21
, pp. 677-684
-
-
Liu, Y.1
Zhang, S.2
Cai, Y.3
-
29
-
-
34547437582
-
Combination immunotherapy with anti-CD20 and anti-HLA-DR monoclonal antibodies induces synergistic anti-lymphoma effects in human lymphoma cell lines
-
Tobin E, Denardo G, Zhang N, Epstein AL, Liu C, et al. (2007) Combination immunotherapy with anti-CD20 and anti-HLA-DR monoclonal antibodies induces synergistic anti-lymphoma effects in human lymphoma cell lines. Leuk Lymphoma 48: 944-56.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 944-956
-
-
Tobin, E.1
Denardo, G.2
Zhang, N.3
Epstein, A.L.4
Liu, C.5
-
30
-
-
84859360525
-
Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy Cell Death Dis
-
Shi WY, Xiao D, Wang L, Dong LH, Yan ZX, et al. (2012) Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy Cell Death Dis. 3: e275.
-
(2012)
, vol.3
-
-
Shi, W.Y.1
Xiao, D.2
Wang, L.3
Dong, L.H.4
Yan, Z.X.5
-
31
-
-
77955899223
-
Beclin 1 expression: a predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type
-
Huang JJ, Li HR, Huang Y, Jiang WQ, Xu RH, et al. (2010) Beclin 1 expression: a predictor of prognosis in patients with extranodal natural killer T-cell lymphoma, nasal type. Autophagy 6: 777-83.
-
(2010)
Autophagy
, vol.6
, pp. 777-783
-
-
Huang, J.J.1
Li, H.R.2
Huang, Y.3
Jiang, W.Q.4
Xu, R.H.5
-
32
-
-
84856107017
-
Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells
-
Zang L, Xu Q, Ye Y, Li X, Liu Y, et al. (2012) Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells. Arch Biochem Biophys 518: 31-41.
-
(2012)
Arch Biochem Biophys
, vol.518
, pp. 31-41
-
-
Zang, L.1
Xu, Q.2
Ye, Y.3
Li, X.4
Liu, Y.5
-
33
-
-
77954242444
-
Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas
-
Nicotra G, Mercalli F, Peracchio C, Castino R, Follo C, et al. (2010) Autophagy-active beclin-1 correlates with favourable clinical outcome in non-Hodgkin lymphomas. Mod Pathol 23: 937-50.
-
(2010)
Mod Pathol
, vol.23
, pp. 937-950
-
-
Nicotra, G.1
Mercalli, F.2
Peracchio, C.3
Castino, R.4
Follo, C.5
-
34
-
-
77950886468
-
Methods for detecting autophagy and determining autophagy-induced cell death
-
Chen Y, Azad MB, Gibson SB, (2010) Methods for detecting autophagy and determining autophagy-induced cell death. Can J Physiol Pharmacol 88: 285-95.
-
(2010)
Can J Physiol Pharmacol
, vol.88
, pp. 285-295
-
-
Chen, Y.1
Azad, M.B.2
Gibson, S.B.3
-
35
-
-
84872845688
-
The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes
-
Heckmann BL, Yang X, Zhang X, Liu J, (2012) The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes. Br J Pharmacol 168: 163-71.
-
(2012)
Br J Pharmacol
, vol.168
, pp. 163-171
-
-
Heckmann, B.L.1
Yang, X.2
Zhang, X.3
Liu, J.4
-
36
-
-
84861862397
-
The quinoline imidoselenocarbamate EI201 blocks the AKT/mTOR pathway and targets cancer stem cells leading to a strong antitumor activity
-
Ibanez E, Agliano A, Prior C, Nguewa P, Redrado M, et al. (2012) The quinoline imidoselenocarbamate EI201 blocks the AKT/mTOR pathway and targets cancer stem cells leading to a strong antitumor activity. Curr Med Chem 19: 3031-43.
-
(2012)
Curr Med Chem
, vol.19
, pp. 3031-3043
-
-
Ibanez, E.1
Agliano, A.2
Prior, C.3
Nguewa, P.4
Redrado, M.5
-
37
-
-
84855588783
-
Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury
-
Walker CL, Walker MJ, Liu NK, Risberg EC, Gao X, et al. (2012) Systemic bisperoxovanadium activates Akt/mTOR, reduces autophagy, and enhances recovery following cervical spinal cord injury. PLoS One 7: e30012.
-
(2012)
PLoS One
, vol.7
-
-
Walker, C.L.1
Walker, M.J.2
Liu, N.K.3
Risberg, E.C.4
Gao, X.5
-
38
-
-
84872362045
-
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
-
Bravo-San Pedro JM, Niso-Santano M, Gomez-Sanchez R, Pizarro-Estrella E, Aiastui-Pujana A, et al. (2013) The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway. Cell Mol Life Sci 70: 121-36.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 121-136
-
-
Bravo-San Pedro, J.M.1
Niso-Santano, M.2
Gomez-Sanchez, R.3
Pizarro-Estrella, E.4
Aiastui-Pujana, A.5
-
39
-
-
84856044276
-
Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells
-
Zeng Y, Yang X, Wang J, Fan J, Kong Q, et al. (2012) Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells. PLoS One 7: e30312.
-
(2012)
PLoS One
, vol.7
-
-
Zeng, Y.1
Yang, X.2
Wang, J.3
Fan, J.4
Kong, Q.5
-
40
-
-
64549084052
-
Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death
-
Park KJ, Lee SH, Lee CH, Jang JY, Chung J, et al. (2009) Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death. Biochem Biophys Res Commun 382: 726-9.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 726-729
-
-
Park, K.J.1
Lee, S.H.2
Lee, C.H.3
Jang, J.Y.4
Chung, J.5
-
41
-
-
84887270621
-
Suppression of Autophagy Enhanced Growth Inhibition and Apoptosis of Interferon-β in Human Glioma Cells
-
Li Y, Zhu H, Zeng X, Fan J, Qian X, et al. (2013) Suppression of Autophagy Enhanced Growth Inhibition and Apoptosis of Interferon-β in Human Glioma Cells. Mol Neurobiol. 47: 1000-10.
-
(2013)
Mol Neurobiol
, vol.47
, pp. 1000-1010
-
-
Li, Y.1
Zhu, H.2
Zeng, X.3
Fan, J.4
Qian, X.5
-
42
-
-
84872845688
-
The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes
-
Heckmann BL, Yang X, Zhang X, Liu J, (2012) The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes. Br J Pharmacol 168: 163-71.
-
(2012)
Br J Pharmacol
, vol.168
, pp. 163-171
-
-
Heckmann, B.L.1
Yang, X.2
Zhang, X.3
Liu, J.4
-
43
-
-
84865324715
-
Antitumor effect of arsenic trioxide in human K562 and K562/ADM cells by autophagy
-
Cheng J, Wei HL, Chen J, Xie B, (2012) Antitumor effect of arsenic trioxide in human K562 and K562/ADM cells by autophagy. Toxicol Mech Methods 22: 512-9.
-
(2012)
Toxicol Mech Methods
, vol.22
, pp. 512-519
-
-
Cheng, J.1
Wei, H.L.2
Chen, J.3
Xie, B.4
-
44
-
-
84866614835
-
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
-
Singh BN, Kumar D, Shankar S, Srivastava RK, (2012) Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells. Biochem Pharmacol 84: 1154-63.
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 1154-1163
-
-
Singh, B.N.1
Kumar, D.2
Shankar, S.3
Srivastava, R.K.4
|