Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis

Journal of Biological Chemistry

Volumn 288, Issue 34, 2013, Pages 24753-24763

  Amako, Yutaka ^a   Igloi, Zsofia ^a   Mankouri, Jamel ^a   Kazlauskas, Arunas ^b   Saksela, Kalle ^b   Dallas, Mark ^a,c   Peers, Chris ^a   Harris, Mark ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNEL ACTIVITY; CO-IMMUNOPRECIPITATIONS; HEPATITIS C VIRUS; HOST CELL PROTEIN; INDUCED APOPTOSIS; POTASSIUM CHANNELS; POTASSIUM EFFLUX; WESTERN-BLOT ANALYSIS;

AMINO ACIDS; CELL DEATH; OXIDATIVE STRESS; POTASSIUM; PROTEINS; VIRUSES;

ENZYMES;

MITOGEN ACTIVATED PROTEIN KINASE P38; MIXED LINEAGE KINASE 3; NONSTRUCTURAL PROTEIN 5A; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV2.1; POTASSIUM ION; PROTEIN SH3; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STIMULATION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INHIBITION KINETICS; OXIDATIVE STRESS; PHAGE DISPLAY; POTASSIUM BALANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UPREGULATION; VIRUS CELL INTERACTION; WESTERN BLOTTING;

APOPTOSIS; HEPATITIS C VIRUS; ION CHANNELS; KV2.1; MIXED LINEAGE KINASE 3; NS5A; OXIDATIVE STRESS; SH3 DOMAINS;

APOPTOSIS; CELL LINE, TUMOR; HEPACIVIRUS; HEPATITIS C; HUMANS; ION TRANSPORT; MAP KINASE KINASE KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POTASSIUM; SHAB POTASSIUM CHANNELS; SRC HOMOLOGY DOMAINS; UP-REGULATION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84883158033     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.491985     Document Type: Article

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