Antiproliferative activity of abietane diterpenoids against human tumor cells

Journal of Natural Products

Volumn 76, Issue 8, 2013, Pages 1413-1423

  Burmistrova, Olga ^a   Simões, M Fátima ^b   Rijo, Patrícia ^b,c   Quintana, José ^a   Bermejo, Jaime ^d   Estévez, Francisco ^a  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^c UNIVERSIDADE LUSÓFONA DE HUMANIDADES E TECNOLOGIAS   (Portugal)

^d INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

11,12 DI O ACETYL 14 DEOXYCOLEON U; 2 OXOCANDESALVONE A; 6,11,12 TRI O ACETYL 14 DEOXYCOLEON U; 6BETA,7ALPHA DIACETOXY 12 O ACETYLROYLEANONE; 7ALPHA ACETOXY 6BETA (4 CHLORO)BENZOYLOXY 12 O (4 CHLORO)BENZOYLROYLEANONE; 7ALPHA ACETOXY 6BETA (4 NITRO)BENZOYLOXYROYLEAN; 7ALPHA ACETOXY 6BETA BENZOYLOXY 12 O BENZOYLROYLEANONE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 CHLORO)BENZOYLROYLEANONE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 METHOXY)BENZOYLROYLEANONE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 NITRO)BENZOYLROYLEANONE; 7ALPHA ACETOXY 6BETA HYDROXYROYLEANONE; 7ALPHA ETHOXYROYLEANONE; ABIETANE DERIVATIVE; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; COLEON U; CYTOCHROME C; CYTOTOXIC AGENT; DITERPENOID; INUROYLEANOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN BCL XL; ROYLEANONE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TAXODIONE; TAXODONE; TEUVINCENONE A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL CYCLE ARREST; CELL DEATH; CELL STRAIN HL 60; CELL STRAIN MCF 7; CELL STRAIN U937; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; DRUG MECHANISM; ENZYME INHIBITION; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TUMOR CELL;

AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 8; CYTOCHROMES C; DITERPENES; DITERPENES, ABIETANE; DRUG SCREENING ASSAYS, ANTITUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HL-60 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84883155925     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400172k     Document Type: Article

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