Antimycobacterial metabolites from Plectranthus: Royleanone derivatives against Mycobacterium tuberculosis strains

Chemistry and Biodiversity

Volumn 7, Issue 4, 2010, Pages 922-932

  Rijo, Patrícia ^a   Simões, M Fátima ^a   Francisco, A Paula ^a   Rojas, Rosario ^b   Gilman, Robert H ^b   Vaisberg, Abraham J ^b   Rodríguez, Benjamín ^c   Moiteiro, Cristina ^d  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^c INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^d IP   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

6,7 DEHYDROROYLEANONE; 6BETA,7ALPHA DIACETOXY 12 O ACETYLROYLEANONE(6BETA,7ALPHA) 11,14 DIOXOABIETA 8,12 DIENE 6,7,12 TRIYL TRIACETATE; 6BETA,7ALPHA DIHYDROXYROYLEANONE; 6BETA,7BETA DIACETOXYROYLEANONE(6BETA,7ALPHA) 12 HYDROXY 11,14 DIOXOABIETA 8,12 DIENE 6,7 DIYL DIACETATE; 7ALPHA ACETOXY 6ALPHA [(4 CHLOROBENZOYL)OXY] 12 O (4 CHLOROBENZOYL)ROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 11,14 DIOXOABIETA 8,12 DIENE 6,12 DIYL BIS(4 CHLOROBENZOATE); 7ALPHA ACETOXY 6BETA (4 NITROBENZOYL)OXYROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 12 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 12 YL 4 NITROBENZOATE; 7ALPHA ACETOXY 6BETA (PROPANOYLOXY) 12 O PROPANOYLROYLEANONE(6BETA,7ALPHA) 7 (ACETOXY) 11,14 DIOXOABIETA 8,12 DIENE 6,12 DIYL DIPROPANOATE; 7ALPHA ACETOXY 6BETA BENZOYLOXY 12 O BENZOYLROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 11,14 DIOXOABIETA 8,12 DIENE 6,12 DIYL DIBENZOATE; 7ALPHA ACETOXY 6BETA BUTANOYLOXYROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 12 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 6 YL BUTANOATE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 CHLOROBENZOYL)ROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 6 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 12 YL 4 CHLOROBENZOATE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 METHOXYBENZOYL)ROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 6 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 12 YL 4 METHOXYBENZOATE; 7ALPHA ACETOXY 6BETA HYDROXY 12 O (4 NITROBENZOYL)ROYLEANONE(6BETA,7ALPHA) 7 (ACETYLOXY) 6 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 12 YL 4 NITROBENZOATE; 7ALPHA ACETOXY 6BETA HYDROXYROYLEANONE; 7ALPHA ACETOXY 6BETA PROPANOYLOXYROYLEANONE(6BETA,7ALPHA) 7 (ACETLOXY) 12 HYDROXY 11,14 DIOXOABIETA 8,12 DIEN 6 YL PROPANOATE; ANTIMYCOBACTERIAL AGENT; DITERPENOID; ENT 12BETA ACETOXYKAUR 16 EN 19 OIC ACID; ENT 7BETA HYDROXY 15BETA,16BETA EPOXYKAURAN 19 OIC ACID; ENT KAUR 15 EN 19 OIC ACID; HORMINONE; ISONIAZID; QUINONE DERIVATIVE; RHINOCEROTINOIC ACID; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CELL STRAIN 3T3; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLECTRANTHUS; PLECTRANTHUS GRANDIDENTATUS; STRUCTURE ACTIVITY RELATION; VERO CELL;

3T3 CELLS; ANIMALS; ANTI-BACTERIAL AGENTS; CERCOPITHECUS AETHIOPS; DITERPENES, ABIETANE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; MICE; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PLECTRANTHUS; VERO CELLS;

MYCOBACTERIUM TUBERCULOSIS; PLECTRANTHUS;

EID: 77951197862     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200900099     Document Type: Article

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