Engineering the biosynthesis of the polyketide-nonribosomal peptide collismycin A for generation of analogs with neuroprotective activity

Chemistry and Biology

Volumn 20, Issue 8, 2013, Pages 1022-1032

  Garcia, Ignacio ^a   Vior, Natalia M ^a   González Sabín, Javier ^b   Braña, Alfredo F ^a   Rohr, Jürgen ^c   Moris, Francisco ^b   Méndez, Carmen ^a   Salas, José A ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^b Campus El Cristo   (Spain)

^c University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2' BIPYRIDINE DERIVATIVE; COLLISMYCIN A; COLLISMYCIN C; COLLISMYCIN D; COLLISMYCIN DA; COLLISMYCIN DERIVATIVE; COLLISMYCIN DH; COLLISMYCIN DN; COLLISMYCIN DS; COLLISMYCIN H; COLLISMYCIN H1; COLLISMYCIN H2; COLLISMYCIN H3; COLLISMYCIN H4; COLLISMYCIN H5; CYTOTOXIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOCATALYSIS; BIOENGINEERING; BIOSYNTHESIS; BRAIN REGION; CONTROLLED STUDY; DRUG CYTOTOXICITY; GENE INACTIVATION; GENE INSERTION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

DANIO RERIO;

EID: 84883147489     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.06.014     Document Type: Article

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