Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus

Molecular and General Genetics

Volumn 261, Issue 2, 1999, Pages 216-225

  Prado, L ^a   Lombo F ^a   Brana A F ^a   Mendez C ^a   Rohr, J ^b   Salas, J A ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Acyl CoA ligase; Ketoreductases; Loading enzyme; Oxygenases; Polyketides

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; GENE PRODUCT; LONG CHAIN FATTY ACID COENZYME A LIGASE; MITHRAMYCIN; MUTANT PROTEIN; OXIDOREDUCTASE; OXYGEN; OXYGENASE; POLYKETIDE; SYNTHETASE;

AMINO ACID SEQUENCE; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; GENE INACTIVATION; GENE LOCUS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STREPTOMYCES;

AMINO ACID SEQUENCE; ANTIBIOTICS, ANTINEOPLASTIC; CHROMOSOMES, BACTERIAL; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; MULTIGENE FAMILY; MUTAGENESIS, INSERTIONAL; OXYGENASES; PLICAMYCIN; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES;

ACTINOBACTERIA (CLASS); STREPTOMYCES; STREPTOMYCES ARGILLACEUS; UNCULTURED ACTINOMYCETE;

EID: 0033036925     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050960     Document Type: Article

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