Glucocorticosteroids in Nano-Sterically Stabilized Liposomes Are Efficacious for Elimination of the Acute Symptoms of Experimental Cerebral Malaria

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Waknine Grinberg, Judith H ^a,b   Even Chen, Simcha ^a   Avichzer, Jasmine ^c   Turjeman, Keren ^a   Bentura Marciano, Annael ^b   Haynes, Richard K ^d   Weiss, Lola ^c   Allon, Nahum ^a   Ovadia, Haim ^c   Golenser, Jacob ^b   Barenholz, Yechezkel ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; ARTEMISONE; BETAMETHASONE SUCCINATE; CHEMOKINE; CHLOROQUINE; CYTOKINE; DIHYDROARTEMISININ; GLUCOCORTICOID; LIPOSOME; METHYLPREDNISOLONE SODIUM SUCCINATE; NANOSTERICALLY STABILIZED LIPOSOME; PLACEBO; QUININE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN MALARIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG LIVER LEVEL; DRUG TISSUE LEVEL; ENCEPHALITIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALE; MOUSE; NANOENCAPSULATION; NONHUMAN; PLASMODIUM BERGHEI INFECTION; PLASMODIUM FALCIPARUM; SYMPTOM;

ACUTE DISEASE; ANIMALS; BASE SEQUENCE; BETAMETHASONE; DISEASE MODELS, ANIMAL; DNA PRIMERS; LIPOSOMES; MALARIA, CEREBRAL; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; NANOPARTICLES; PLASMODIUM BERGHEI; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84883074450     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072722     Document Type: Article

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