Inhibition of src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells

Toxicon

Volumn 74, Issue , 2013, Pages 56-67

  Tsai, Pei Chien ^a   Chu, Chiao Lun ^a   Chiu, Chien Chih ^a   Chang, Long Sen ^b   Lin, Shinne Ren ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

CTX III; ERK1 2; MDA MB 231; Migration; PI3K Akt; Src

Indexed keywords

ANTINEOPLASTIC AGENT; CARDIOTOXIN III; FOCAL ADHESION KINASE; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PAXILLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

CTX III; ERK1/2; MDA-MB-231; MIGRATION; PI3K/AKT; SRC;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COBRA CARDIOTOXIN PROTEINS; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; PAXILLIN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SRC-FAMILY KINASES;

EID: 84882957832     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2013.07.021     Document Type: Article

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