Detection of apoptosis using cyclic luciferase in living mammals

Methods in Molecular Biology

Volumn 574, Issue , 2009, Pages 105-114

  Kanno, Akira ^a   Umezawa, Yoshio ^a   Ozawa, Takeaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; caspases; imaging; luciferases; luminescence

Indexed keywords

EID: 84934439113     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-321-3_9     Document Type: Article

References (12)

1. Arends, M. J., and Wyllie, A. H. (1991) Apoptosis - Mechanisms and roles in pathology. Int Rev Exp Pathol 32, 223-254.
2. Ellis, R. E., Yuan, J. Y., and Horvitz, H. R. (1991) Mechanisms and functions of celldeath. Annu Rev Cell Biol 7, 663-698.
3. Cohen, J. J., Duke, R. C., Fadok, V. A., and Sellins, K. S. (1992) Apoptosis and programmed cell-death in immunity. Annu Rev Immunol 10, 267-293.
4. Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem J 326, 1-16.
5. Nijhawan, D., Honarpour, N., andWang, X. D. (2000) Apoptosis in neural development and disease. Annu Rev Neurosci 23, 73-87.
6. Riedout, H. J., and Stefanis, L. (2001) Caspase inhibition: a potential therapeutic strategy in neurological diseases. Histol Histopathol 16, 895-908.
7. Thornberry, N. A., and Lazebnik, Y. (1998) Caspases: enemies within. Science 281, 1312-1316.
8. Budihardjo, I., Oliver, H., Lutter, M., Luo, X., and Wang, X. D. (1999) Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15, 269-290.
9. Wolf, B. B., and Green, D. R. (1999) Suicidal tendencies: apoptotic cell death by caspase family proteinases. J Biol Chem 274, 20049-20052.
10. Kanno, A., Yamanaka, Y., Hirano, H., Umezawa, Y., and Ozawa, T. (2007) Cyclic luciferase for real-time sensing of caspase-3 activities in living mammals. Angew Chem Int Ed. 46, 7595-7599.
11. Wu, H., Hu, Z. M., and Liu, X. Q. (1998) Protein trans-splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803. Proc Natl Acad Sci USA 95, 9226-9231.
12. Li, X. Q., Zhao, X. N., Fang, Y., Jiang, X., Duong, T., Fan, C., Huang, C. C., and Kain, S. R. (1998) Generation of destabilized green fluorescent protein transcription reporter. J Biol Chem 273, 34970-34975.