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Volumn 25, Issue 5, 2013, Pages 633-641

How integrins control breast biology

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

EID: 84882848445     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.06.010     Document Type: Review
Times cited : (50)

References (91)
  • 1
    • 79952201972 scopus 로고    scopus 로고
    • Cell-matrix interactions in mammary gland development and breast cancer
    • Muschler J., Streuli C.H. Cell-matrix interactions in mammary gland development and breast cancer. Cold Spring Harb Perspect Biol 2010, 2:a003202.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Muschler, J.1    Streuli, C.H.2
  • 2
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: a dynamic niche in cancer progression
    • Lu P., Weaver V.M., Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 2012, 196:395-406.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 4
    • 61949262034 scopus 로고    scopus 로고
    • Integrins and cell-fate determination
    • Streuli C.H. Integrins and cell-fate determination. J Cell Sci 2009, 122:171-177.
    • (2009) J Cell Sci , vol.122 , pp. 171-177
    • Streuli, C.H.1
  • 5
    • 33847673133 scopus 로고    scopus 로고
    • The extracellular matrix as an adhesion checkpoint for mammary epithelial function
    • Katz E., Streuli C.H. The extracellular matrix as an adhesion checkpoint for mammary epithelial function. Int J Biochem Cell Biol 2007, 39:715-726.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 715-726
    • Katz, E.1    Streuli, C.H.2
  • 6
    • 79960277917 scopus 로고    scopus 로고
    • A hitchhiker's guide to mechanobiology
    • Eyckmans J., Boudou T., Yu X., Chen C.S. A hitchhiker's guide to mechanobiology. Dev Cell 2011, 21:35-47.
    • (2011) Dev Cell , vol.21 , pp. 35-47
    • Eyckmans, J.1    Boudou, T.2    Yu, X.3    Chen, C.S.4
  • 7
    • 77957283664 scopus 로고    scopus 로고
    • Beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression
    • Huck L., Pontier S.M., Zuo D.M., Muller W.J. beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression. Proc Natl Acad Sci USA 2010, 107:15559-15564.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15559-15564
    • Huck, L.1    Pontier, S.M.2    Zuo, D.M.3    Muller, W.J.4
  • 8
    • 5144235557 scopus 로고    scopus 로고
    • Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction
    • White D.E., Kurpios N.A., Zuo D., Hassell J.A., Blaess S., Mueller U., Muller W.J. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 2004, 6:159-170.
    • (2004) Cancer Cell , vol.6 , pp. 159-170
    • White, D.E.1    Kurpios, N.A.2    Zuo, D.3    Hassell, J.A.4    Blaess, S.5    Mueller, U.6    Muller, W.J.7
  • 15
    • 54249086214 scopus 로고    scopus 로고
    • The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis
    • Vaillant F., Asselin-Labat M.-L., Shackleton M., Forrest N.C., Lindeman G.J., Visvader J.E. The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis. Cancer Res 2008, 68:7711-7717.
    • (2008) Cancer Res , vol.68 , pp. 7711-7717
    • Vaillant, F.1    Asselin-Labat, M.-L.2    Shackleton, M.3    Forrest, N.C.4    Lindeman, G.J.5    Visvader, J.E.6
  • 16
    • 84861514155 scopus 로고    scopus 로고
    • CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling
    • Lo P.-K., Kanojia D., Liu X., Singh U.P., Berger F.G., Wang Q., Chen H. CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling. Oncogene 2012, 31:2614-2626.
    • (2012) Oncogene , vol.31 , pp. 2614-2626
    • Lo, P.-K.1    Kanojia, D.2    Liu, X.3    Singh, U.P.4    Berger, F.G.5    Wang, Q.6    Chen, H.7
  • 17
    • 36849013105 scopus 로고    scopus 로고
    • Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line
    • Cariati M., Naderi A., Brown J.P., Smalley M.J., Pinder S.E., Caldas C., Purushotham A.D. Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line. Int J Cancer 2008, 122:298-304.
    • (2008) Int J Cancer , vol.122 , pp. 298-304
    • Cariati, M.1    Naderi, A.2    Brown, J.P.3    Smalley, M.J.4    Pinder, S.E.5    Caldas, C.6    Purushotham, A.D.7
  • 18
    • 0034678367 scopus 로고    scopus 로고
    • Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization
    • Gilmore A.P., Metcalfe A.D., Romer L.H., Streuli C.H. Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization. J Cell Biol 2000, 149:431-446.
    • (2000) J Cell Biol , vol.149 , pp. 431-446
    • Gilmore, A.P.1    Metcalfe, A.D.2    Romer, L.H.3    Streuli, C.H.4
  • 21
    • 58349108303 scopus 로고    scopus 로고
    • Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells
    • Luo M., Fan H., Nagy T., Wei H., Wang C., Liu S., Wicha M.S., Guan J.-L. Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells. Cancer Res 2009, 69:466-474.
    • (2009) Cancer Res , vol.69 , pp. 466-474
    • Luo, M.1    Fan, H.2    Nagy, T.3    Wei, H.4    Wang, C.5    Liu, S.6    Wicha, M.S.7    Guan, J.-L.8
  • 22
    • 84858118438 scopus 로고    scopus 로고
    • Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling
    • Goel H.L., Pursell B., Standley C., Fogarty K., Mercurio A.M. Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling. J Cell Sci 2012, 125:497-506.
    • (2012) J Cell Sci , vol.125 , pp. 497-506
    • Goel, H.L.1    Pursell, B.2    Standley, C.3    Fogarty, K.4    Mercurio, A.M.5
  • 24
    • 29244451536 scopus 로고    scopus 로고
    • Key stages in mammary gland development: the mammary end bud as a motile organ
    • Hinck L., Silberstein G.B. Key stages in mammary gland development: the mammary end bud as a motile organ. Breast Cancer Res 2005, 7:245.
    • (2005) Breast Cancer Res , vol.7 , pp. 245
    • Hinck, L.1    Silberstein, G.B.2
  • 26
    • 49049096654 scopus 로고    scopus 로고
    • Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis
    • Lu P., Ewald A.J., Martin G.R., Werb Z. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. Dev Biol 2008, 321:77-87.
    • (2008) Dev Biol , vol.321 , pp. 77-87
    • Lu, P.1    Ewald, A.J.2    Martin, G.R.3    Werb, Z.4
  • 27
    • 41649121862 scopus 로고    scopus 로고
    • Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis
    • Ewald A.J., Brenot A., Duong M., Chan B.S., Werb Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell 2008, 14:570-581.
    • (2008) Dev Cell , vol.14 , pp. 570-581
    • Ewald, A.J.1    Brenot, A.2    Duong, M.3    Chan, B.S.4    Werb, Z.5
  • 29
    • 0017095517 scopus 로고
    • Mesenchyme-dependent morphogenesis and epithelium-specific cytodifferentiation in mouse mammary gland
    • Sakakura T., Nishizuka Y., Dawe C.J. Mesenchyme-dependent morphogenesis and epithelium-specific cytodifferentiation in mouse mammary gland. Science 1976, 194:1439-1441.
    • (1976) Science , vol.194 , pp. 1439-1441
    • Sakakura, T.1    Nishizuka, Y.2    Dawe, C.J.3
  • 31
    • 80051679069 scopus 로고    scopus 로고
    • A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis
    • Daley W.P., Kohn J.M., Larsen M. A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis. Dev Dyn 2011, 240:2069-2083.
    • (2011) Dev Dyn , vol.240 , pp. 2069-2083
    • Daley, W.P.1    Kohn, J.M.2    Larsen, M.3
  • 33
    • 84871568040 scopus 로고    scopus 로고
    • Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1
    • Mori H., Lo A.T., Inman J.L., Alcaraz J., Ghajar C.M., Mott J.D., Nelson C.M., Chen C.S., Zhang H., Bascom J.L., et al. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development 2013, 140:343-352.
    • (2013) Development , vol.140 , pp. 343-352
    • Mori, H.1    Lo, A.T.2    Inman, J.L.3    Alcaraz, J.4    Ghajar, C.M.5    Mott, J.D.6    Nelson, C.M.7    Chen, C.S.8    Zhang, H.9    Bascom, J.L.10
  • 35
    • 0030876608 scopus 로고    scopus 로고
    • Co-expression of tenascin and fibronectin in epithelial and stromal cells of benign lesions and ductal carcinomas in the human breast
    • Yoshida T., Matsumoto E., Hanamura N., Kalembeyi I., Katsuta K., Ishihara A., Sakakura T. Co-expression of tenascin and fibronectin in epithelial and stromal cells of benign lesions and ductal carcinomas in the human breast. J Pathol 1997, 182:421-428.
    • (1997) J Pathol , vol.182 , pp. 421-428
    • Yoshida, T.1    Matsumoto, E.2    Hanamura, N.3    Kalembeyi, I.4    Katsuta, K.5    Ishihara, A.6    Sakakura, T.7
  • 36
    • 79956072599 scopus 로고    scopus 로고
    • Control of mammary myoepithelial cell contractile function by α3β1 integrin signalling
    • Raymond K., Cagnet S., Kreft M., Janssen H., Sonnenberg A., Glukhova M.A. Control of mammary myoepithelial cell contractile function by α3β1 integrin signalling. EMBO J 2011, 30:1896-1906.
    • (2011) EMBO J , vol.30 , pp. 1896-1906
    • Raymond, K.1    Cagnet, S.2    Kreft, M.3    Janssen, H.4    Sonnenberg, A.5    Glukhova, M.A.6
  • 37
    • 84871712311 scopus 로고    scopus 로고
    • An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
    • Akhtar N., Streuli C.H. An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium. Nat Cell Biol 2013, 15:17-27.
    • (2013) Nat Cell Biol , vol.15 , pp. 17-27
    • Akhtar, N.1    Streuli, C.H.2
  • 42
    • 33747423320 scopus 로고    scopus 로고
    • Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia
    • Akhtar N., Streuli C.H. Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia. J Cell Biol 2006, 173:781-793.
    • (2006) J Cell Biol , vol.173 , pp. 781-793
    • Akhtar, N.1    Streuli, C.H.2
  • 43
    • 66149121885 scopus 로고    scopus 로고
    • Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation
    • Akhtar N., Marlow R., Lambert E., Schatzmann F., Lowe E.T., Cheung J., Katz E., Li W., Wu C., Dedhar S., et al. Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development 2009, 136:1019-1027.
    • (2009) Development , vol.136 , pp. 1019-1027
    • Akhtar, N.1    Marlow, R.2    Lambert, E.3    Schatzmann, F.4    Lowe, E.T.5    Cheung, J.6    Katz, E.7    Li, W.8    Wu, C.9    Dedhar, S.10
  • 44
    • 0032540383 scopus 로고    scopus 로고
    • Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases
    • Edwards G.M., Wilford F.H., Liu X., Hennighausen L., Djiane J., Streuli C.H. Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases. J Biol Chem 1998, 273:9495-9500.
    • (1998) J Biol Chem , vol.273 , pp. 9495-9500
    • Edwards, G.M.1    Wilford, F.H.2    Liu, X.3    Hennighausen, L.4    Djiane, J.5    Streuli, C.H.6
  • 46
    • 84862938301 scopus 로고    scopus 로고
    • The RhoA-Rok-myosin II pathway is involved in extracellular matrix-mediated regulation of prolactin signaling in mammary epithelial cells
    • Du J.-Y., Chen M.-C., Hsu T.-C., Wang J.-H., Brackenbury L., Lin T.-H., Wu Y.-Y., Yang Z., Streuli C.H., Lee Y.-J. The RhoA-Rok-myosin II pathway is involved in extracellular matrix-mediated regulation of prolactin signaling in mammary epithelial cells. J Cell Physiol 2012, 227:1553-1560.
    • (2012) J Cell Physiol , vol.227 , pp. 1553-1560
    • Du, J.-Y.1    Chen, M.-C.2    Hsu, T.-C.3    Wang, J.-H.4    Brackenbury, L.5    Lin, T.-H.6    Wu, Y.-Y.7    Yang, Z.8    Streuli, C.H.9    Lee, Y.-J.10
  • 47
    • 84868111953 scopus 로고    scopus 로고
    • Mechanosensitive mechanisms in transcriptional regulation
    • Mammoto A., Mammoto T., Ingber D.E. Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci 2012, 10.1242/jcs.093005.
    • (2012) J Cell Sci
    • Mammoto, A.1    Mammoto, T.2    Ingber, D.E.3
  • 48
    • 62149091091 scopus 로고    scopus 로고
    • Signal co-operation between integrins and other receptor systems
    • Streuli C.H., Akhtar N. Signal co-operation between integrins and other receptor systems. Biochem J 2009, 418:491-506.
    • (2009) Biochem J , vol.418 , pp. 491-506
    • Streuli, C.H.1    Akhtar, N.2
  • 49
    • 84863804465 scopus 로고    scopus 로고
    • Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells
    • Jeanes A.I., Wang P., Moreno-Layseca P., Paul N., Cheung J., Tsang R., Akhtar N., Foster F.M., Brennan K., Streuli C.H. Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells. J Biol Chem 2012, 287:24103-24112.
    • (2012) J Biol Chem , vol.287 , pp. 24103-24112
    • Jeanes, A.I.1    Wang, P.2    Moreno-Layseca, P.3    Paul, N.4    Cheung, J.5    Tsang, R.6    Akhtar, N.7    Foster, F.M.8    Brennan, K.9    Streuli, C.H.10
  • 50
    • 84855737428 scopus 로고    scopus 로고
    • The C terminus of talin links integrins to cell cycle progression
    • Wang P., Ballestrem C., Streuli C.H. The C terminus of talin links integrins to cell cycle progression. J Cell Biol 2011, 195:499-513.
    • (2011) J Cell Biol , vol.195 , pp. 499-513
    • Wang, P.1    Ballestrem, C.2    Streuli, C.H.3
  • 51
    • 84871158029 scopus 로고    scopus 로고
    • Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study
    • Dos Santos P.B., Zanetti J.S., Ribeiro-Silva A., Beltrao E.I. Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study. Diagn Pathol 2012, 7:104.
    • (2012) Diagn Pathol , vol.7 , pp. 104
    • Dos Santos, P.B.1    Zanetti, J.S.2    Ribeiro-Silva, A.3    Beltrao, E.I.4
  • 53
    • 84879414971 scopus 로고    scopus 로고
    • Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways
    • doi:10.1038/onc.2012.320
    • Bianchi-Smiraglia A., Paesante S., Bakin A.V. Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene 2012, doi:10.1038/onc.2012.320.
    • (2012) Oncogene
    • Bianchi-Smiraglia, A.1    Paesante, S.2    Bakin, A.V.3
  • 54
    • 84964875096 scopus 로고    scopus 로고
    • Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors
    • Goodman S.L., Grote H.J., Wilm C. Matched rabbit monoclonal antibodies against αv-series integrins reveal a novel αvβ3-LIBS epitope, and permit routine staining of archival paraffin samples of human tumors. Biol Open 2012, 1:329-340.
    • (2012) Biol Open , vol.1 , pp. 329-340
    • Goodman, S.L.1    Grote, H.J.2    Wilm, C.3
  • 55
    • 55649111840 scopus 로고    scopus 로고
    • The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer
    • Lane J., Martin T.A., Mansel R.E., Jiang W.G. The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer. Int Seminars Surg Oncol 2008, 5.
    • (2008) Int Seminars Surg Oncol , pp. 5
    • Lane, J.1    Martin, T.A.2    Mansel, R.E.3    Jiang, W.G.4
  • 56
    • 45949098871 scopus 로고    scopus 로고
    • Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer
    • Lee K., Liu Y., Mo J.Q., Zhang J., Dong Z., Lu S. Vav3 oncogene activates estrogen receptor and its overexpression may be involved in human breast cancer. BMC Cancer 2008, 8:158.
    • (2008) BMC Cancer , vol.8 , pp. 158
    • Lee, K.1    Liu, Y.2    Mo, J.Q.3    Zhang, J.4    Dong, Z.5    Lu, S.6
  • 61
    • 39749084606 scopus 로고    scopus 로고
    • Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance
    • Lu S., Simin K., Khan A., Mercurio A.M. Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance. Clin Cancer Res 2008, 14:1050-1058.
    • (2008) Clin Cancer Res , vol.14 , pp. 1050-1058
    • Lu, S.1    Simin, K.2    Khan, A.3    Mercurio, A.M.4
  • 62
    • 84857120037 scopus 로고    scopus 로고
    • Outgrowth of single oncogene-expressing cells from suppressive epithelial environments
    • Leung C.T., Brugge J.S. Outgrowth of single oncogene-expressing cells from suppressive epithelial environments. Nature 2012, 482:410-413.
    • (2012) Nature , vol.482 , pp. 410-413
    • Leung, C.T.1    Brugge, J.S.2
  • 64
    • 84869000970 scopus 로고    scopus 로고
    • Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis
    • McCaffrey L.M., Montalbano J., Mihai C., Macara I.G. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell 2012, 22:601-614.
    • (2012) Cancer Cell , vol.22 , pp. 601-614
    • McCaffrey, L.M.1    Montalbano, J.2    Mihai, C.3    Macara, I.G.4
  • 65
    • 84873410310 scopus 로고    scopus 로고
    • Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion
    • Xue B., Krishnamurthy K., Allred D.C., Muthuswamy S.K. Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Nat Cell Biol 2012, 15:189-200.
    • (2012) Nat Cell Biol , vol.15 , pp. 189-200
    • Xue, B.1    Krishnamurthy, K.2    Allred, D.C.3    Muthuswamy, S.K.4
  • 69
    • 80053374576 scopus 로고    scopus 로고
    • The role of β3-integrins in tumor angiogenesis: context is everything
    • Robinson S.D., Hodivala-Dilke K.M. The role of β3-integrins in tumor angiogenesis: context is everything. Curr Opin Cell Biol 2011, 23:630-637.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 630-637
    • Robinson, S.D.1    Hodivala-Dilke, K.M.2
  • 70
    • 28544452516 scopus 로고    scopus 로고
    • A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas
    • Taverna D., Crowley D., Connolly M., Bronson R.T., Hynes R.O. A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas. Cancer Res 2005, 65:10324-10329.
    • (2005) Cancer Res , vol.65 , pp. 10324-10329
    • Taverna, D.1    Crowley, D.2    Connolly, M.3    Bronson, R.T.4    Hynes, R.O.5
  • 71
    • 69649089902 scopus 로고    scopus 로고
    • Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition
    • Yang X., Pursell B., Lu S., Chang T.-K., Mercurio A.M. Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition. J Cell Sci 2009, 122:2473-2480.
    • (2009) J Cell Sci , vol.122 , pp. 2473-2480
    • Yang, X.1    Pursell, B.2    Lu, S.3    Chang, T.-K.4    Mercurio, A.M.5
  • 75
    • 79955441991 scopus 로고    scopus 로고
    • Balancing forces: architectural control of mechanotransduction
    • DuFort C.C., Paszek M.J., Weaver V.M. Balancing forces: architectural control of mechanotransduction. Nat Rev Mol Cell Biol 2011, 12:308-319.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 308-319
    • DuFort, C.C.1    Paszek, M.J.2    Weaver, V.M.3
  • 78
    • 79953148385 scopus 로고    scopus 로고
    • Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
    • Provenzano P.P., Keely P.J. Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J Cell Sci 2011, 124:1195-1205.
    • (2011) J Cell Sci , vol.124 , pp. 1195-1205
    • Provenzano, P.P.1    Keely, P.J.2
  • 80
    • 79951841887 scopus 로고    scopus 로고
    • Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells
    • Nagaharu K., Zhang X., Yoshida T., Katoh D., Hanamura N., Kozuka Y., Ogawa T., Shiraishi T., Imanaka-Yoshida K. Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells. Am J Pathol 2011, 178:754-763.
    • (2011) Am J Pathol , vol.178 , pp. 754-763
    • Nagaharu, K.1    Zhang, X.2    Yoshida, T.3    Katoh, D.4    Hanamura, N.5    Kozuka, Y.6    Ogawa, T.7    Shiraishi, T.8    Imanaka-Yoshida, K.9
  • 82
    • 80054962098 scopus 로고    scopus 로고
    • Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study
    • Kharaishvili G., Cizkova M., Bouchalova K., Mgebrishvili G., Kolar Z., Bouchal J. Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study. J Clin Pathol 2011, 64:977-982.
    • (2011) J Clin Pathol , vol.64 , pp. 977-982
    • Kharaishvili, G.1    Cizkova, M.2    Bouchalova, K.3    Mgebrishvili, G.4    Kolar, Z.5    Bouchal, J.6
  • 84
    • 82555189403 scopus 로고    scopus 로고
    • β1-integrin: a potential therapeutic target in the battle against cancer recurrence
    • Barkan D., Chambers A.F. β1-integrin: a potential therapeutic target in the battle against cancer recurrence. Clin Cancer Res 2011, 17:7219-7223.
    • (2011) Clin Cancer Res , vol.17 , pp. 7219-7223
    • Barkan, D.1    Chambers, A.F.2
  • 85
    • 77954353421 scopus 로고    scopus 로고
    • Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
    • Nam J.-M., Onodera Y., Bissell M.J., Park C.C. Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res 2010, 70:5238-5248.
    • (2010) Cancer Res , vol.70 , pp. 5238-5248
    • Nam, J.-M.1    Onodera, Y.2    Bissell, M.J.3    Park, C.C.4
  • 86
    • 49249107671 scopus 로고    scopus 로고
    • Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts [Internet]
    • Park C.C., Zhang H.J., Yao E.S., Park C.J., Bissell M.J. Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts [Internet]. Cancer Res 2008, 68:4398-4405.
    • (2008) Cancer Res , vol.68 , pp. 4398-4405
    • Park, C.C.1    Zhang, H.J.2    Yao, E.S.3    Park, C.J.4    Bissell, M.J.5
  • 87
  • 89
    • 79952748179 scopus 로고    scopus 로고
    • Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study
    • Bäuerle T., Komljenovic D., Merz M., Berger M.R., Goodman S.L., Semmler W. Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study. Int J Cancer 2011, 128:2453-2462.
    • (2011) Int J Cancer , vol.128 , pp. 2453-2462
    • Bäuerle, T.1    Komljenovic, D.2    Merz, M.3    Berger, M.R.4    Goodman, S.L.5    Semmler, W.6
  • 90
    • 81155126053 scopus 로고    scopus 로고
    • Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth
    • Schmid M.C., Avraamides C.J., Foubert P., Shaked Y., Kang S.W., Kerbel R.S., Varner J.A. Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth. Cancer Res 2011, 71:6965-6975.
    • (2011) Cancer Res , vol.71 , pp. 6965-6975
    • Schmid, M.C.1    Avraamides, C.J.2    Foubert, P.3    Shaked, Y.4    Kang, S.W.5    Kerbel, R.S.6    Varner, J.A.7


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