Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

Molecular Cell

Volumn 40, Issue 6, 2010, Pages 877-892

  Sosa, Maria Soledad ^a   Lopez Haber, Cynthia ^a   Yang, Chengfeng ^b   Wang, HongBin ^a   Lemmon, Mark A ^a   Busillo, John M ^c   Luo, Jiansong ^c   Benovic, Jeffrey L ^c   Klein Szanto, Andres ^d   Yagi, Hiroshi ^e   Gutkind, J Silvio ^e   Parsons, Ramon E ^f   Kazanietz, Marcelo G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d FOX CHASE CANCER CENTER   (United States)

^e NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^f NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN P REX1; RAC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CARCINOGENESIS; CELL GROWTH; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; UPREGULATION;

BREAST NEOPLASMS; DISEASE PROGRESSION; FEMALE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; ONCOGENE PROTEINS V-ERBB; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 78650235523     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.11.029     Document Type: Article

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