-
1
-
-
0034680825
-
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia
-
AGANI FH, PICHIULE P, CHAVEZ JC, LAMANNA JC (2000). The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia. J Biol Chem. 275:35863-35867.
-
(2000)
J Biol Chem
, vol.275
, pp. 35863-35867
-
-
Agani, F.H.1
Pichiule, P.2
Chavez, J.C.3
Lamanna, J.C.4
-
2
-
-
4644318828
-
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
-
APPELHOFF RJ, TIAN YM, RAVAL RR, TURLEY H, HARRIS AL, PUGH CW, RATCLIFFE PJ, GLEADLE JM (2004) Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem. 279:38458-38465.
-
(2004)
J Biol Chem
, vol.279
, pp. 38458-38465
-
-
Appelhoff, R.J.1
Tian, Y.M.2
Raval, R.R.3
Turley, H.4
Harris, A.L.5
Pugh, C.W.6
Ratcliffe, P.J.7
Gleadle, J.M.8
-
3
-
-
22144493866
-
Negative and positive regulation of HIF 1: A complex network
-
BÁRDOS JI, ASHCROFT M (2005). Negative and positive regulation of HIF 1: a complex network. Biochim Biophys Acta. 1755:107-20.
-
(2005)
Biochim Biophys Acta
, vol.1755
, pp. 107-120
-
-
Bárdos, J.I.1
Ashcroft, M.2
-
4
-
-
80053597754
-
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
-
BRUNING U, CERONE L, NEUFELD Z, FITZPATRIC SF, CHEONG A, SCHOLZ CC, SIMPSON DA, LEONARD MO, TAMBUWALA MM, CUMMINS EP, and TAYLOR CT (2011). MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia. Mol Cell Biol. 31: 4087-4096.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4087-4096
-
-
Bruning, U.1
Cerone, L.2
Neufeld, Z.3
Fitzpatric, S.F.4
Cheong, A.5
Scholz, C.C.6
Simpson, D.A.7
Leonard, M.O.8
Tambuwala, M.M.9
Cummins, E.P.10
Taylor, C.T.11
-
5
-
-
0036007293
-
Expression of HIF-1alpha by human macrophages: Implications for the use of macrophages in hypoxia-regulated cancer gene therapy
-
BURKE B, TANG N, CORKE KP, TAZZYMAN D, AMERI K, WELLS M, LEWIS CE (2002). Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy. J Pathol.196:204-212.
-
(2002)
J Pathol
, vol.196
, pp. 204-212
-
-
Burke, B.1
Tang, N.2
Corke, K.P.3
Tazzyman, D.4
Ameri, K.5
Wells, M.6
Lewis, C.E.7
-
6
-
-
80052838800
-
Hypoxia-inducible factor-1α mRNA: A new target for destabilization by tristetraprolin in endothelial cells
-
CHAMBOREDONA S, CIAISA D, DESROCHES-CASTANA A, SAVID P, BONOD F, FEIGEA JJ, CHERRADIA N, (2011) Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells. Molecular Biology of the Cell.22:3366-3378.
-
(2011)
Molecular Biology of the Cell
, vol.22
, pp. 3366-3378
-
-
Bonod, F.1
Feigea, J.J.2
Cherradia, N.3
-
7
-
-
77953483108
-
MicroRNA-210. A unique and pleiotropic hypoxamir
-
CHAN SY and LOSCALZO J (2010). MicroRNA-210. A unique and pleiotropic hypoxamir. Cell Cycle 9:1072-1083.
-
(2010)
Cell Cycle
, vol.9
, pp. 1072-1083
-
-
Chan, S.Y.1
Loscalzo, J.2
-
8
-
-
0033566693
-
Reciprocal Positive Regulation of Hypoxia-inducible Factor 1a and Insulin-like Growth Factor 2
-
FELDSER D, AGANI F, IYER NV, PAK B, FERREIRA G, and SEMENZA GL (1999). Reciprocal Positive Regulation of Hypoxia-inducible Factor 1a and Insulin-like Growth Factor 2. Cancer Res. 59:3915-3918.
-
(1999)
Cancer Res
, vol.59
, pp. 3915-3918
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
9
-
-
40949114950
-
Role and regulation of prolyl hydroxylase domain Proteins
-
FONG G-HAND TAKEDA K. (2008) Role and regulation of prolyl hydroxylase domain Proteins. Cell Death and Differentiation 15:635-641.
-
(2008)
Cell Death and Differentiation
, vol.15
, pp. 635-641
-
-
Takeda, K.1
-
10
-
-
70649108815
-
Factors interacting with HIF-1α mRNA: Novel therapeutic targets
-
GALBÁN S and GOROSPE M. (2009) Factors interacting with HIF-1α mRNA: novel therapeutic targets. Curr Pharm Des. 15:3853-3860.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 3853-3860
-
-
Galbán, S.1
Gorospe, M.2
-
11
-
-
0343777395
-
Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions
-
GÖRLACH A, CAMENISCH G, KVIETIKOVA I, VOGT L, WENGER RH, GASSMANN M (2000) Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochim Biophys Acta. 1493:125-134.
-
(2000)
Biochim Biophys Acta
, vol.1493
, pp. 125-134
-
-
Görlach, A.1
Camenisch, G.2
Kvietikova, I.3
Vogt, L.4
Wenger, R.H.5
Gassmann, M.6
-
12
-
-
77649280061
-
Structural Analysis to Determine the Core of Hypoxia Response Network
-
doi:10.1371/journal.pone.0008600
-
HEINER M, SRIRAM K (2010) Structural Analysis to Determine the Core of Hypoxia Response Network. PLoS ONE 5(1): e8600. doi:10.1371/journal. pone.0008600.
-
(2010)
PLoS ONE
, vol.5
, Issue.1
-
-
Heiner, M.1
Sriram, K.2
-
14
-
-
0029859510
-
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
-
JIANG B-H, SEMENZA GL, BAUER C, MARTI HH (1996) Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am. J. Physiol. C1172-C1180.
-
(1996)
Am. J. Physiol
-
-
Jiang, B.-H.1
Semenza, G.L.2
Bauer, C.3
Marti, H.H.4
-
15
-
-
79959425207
-
A HypoxiaInduced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1 Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like
-
KELLY TJ, SOUZA AL, CLISH CB, and PUIGSERVER P (2011). A HypoxiaInduced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1 Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like. Mol and Cell Biol. 31:2696-2706.
-
(2011)
Mol and Cell Biol
, vol.31
, pp. 2696-2706
-
-
Kelly, T.J.1
Souza, A.L.2
Clish, C.B.3
Puigserver, P.4
-
16
-
-
84860332631
-
Assessment of hypoxia-inducible factor-1α mRNA expression in mantis shrimp as a biomarker of environmental hypoxia exposure
-
KODAMA K, RAHMAN MS, HORIGUCHI T, THOMAS P (2012) Assessment of hypoxia-inducible factor-1α mRNA expression in mantis shrimp as a biomarker of environmental hypoxia exposure. Biol Lett. 8:278-281.
-
(2012)
Biol Lett
, vol.8
, pp. 278-281
-
-
Kodama, K.1
Rahman, M.S.2
Horiguchi, T.3
Thomas, P.4
-
17
-
-
0032904863
-
Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain
-
KUO NT, BENHAYON D, PRZYBYLSKI RJ, MARTIN R, LAMANNA JC (1999) Prolonged hypoxia increases vascular endothelial growth factor mRNA and protein in adult mouse brain. J. Appl. Physiol. 86:260-264.
-
(1999)
J. Appl. Physiol
, vol.86
, pp. 260-264
-
-
Kuo, N.T.1
Benhayon, D.2
Przybylski, R.J.3
Martin, R.4
Lamanna, J.C.5
-
18
-
-
0036000028
-
Hypoxia-inducible Factor-1 mRNA Contains an Internal Ribosome Entry Site That Allows Efficient Translation during Normoxia and Hypoxia
-
LANG KJ, KAPPEL A, GOODALL GJ (2002) Hypoxia-inducible Factor-1 mRNA Contains an Internal Ribosome Entry Site That Allows Efficient Translation during Normoxia and Hypoxia. Mol. Biol. Cell. 13:1792-1801.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1792-1801
-
-
Lang, K.J.1
Kappel, A.2
Goodall, G.J.3
-
19
-
-
0032519922
-
Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase expression in the adult rat lung
-
LE CRAS TD, TYLER RC, HORAN MP, MORRIS KG, TUDER RM, MCMURTRY IF, JOHNS RA, ABMAN SH (1998) Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase expression in the adult rat lung. J Clin Invest. 101:795-801.
-
(1998)
J Clin Invest
, vol.101
, pp. 795-801
-
-
Le Cras, T.D.1
Tyler, R.C.2
Horan, M.P.3
Morris, K.G.4
Tuder, R.M.5
Mcmurtry, I.F.6
Johns, R.A.7
Abman, S.H.8
-
20
-
-
0029039195
-
Transcriptional regulation of rat vascular endothelial growth factor gene by hypoxia
-
LEVY AP, LEVY NS, WEGNER S, GOLBERG MA (1995) Transcriptional regulation of rat vascular endothelial growth factor gene by hypoxia. J. Biol. Chem. 270:13333-13340.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 13333-13340
-
-
Levy, A.P.1
Levy, N.S.2
Wegner, S.3
Golberg, M.A.4
-
21
-
-
0027938194
-
Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
-
MCQUILLAN LP, LEUNG GK, MARSDEN PA, KOSTYK SK, KOUREMBANAS S (1994) Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267:H1921-H1927.
-
(1994)
Am. J. Physiol
, vol.267
-
-
McQuillan, L.P.1
Leung, G.K.2
Marsden, P.A.3
Kostyk, S.K.4
Kourembanas, S.5
-
22
-
-
77955509010
-
18S is an appropriate housekeeping gene for in vitro hypoxia experiments
-
NAGELKERKE A, MUJCIC H, WOUTERS B, SPAN PN(2010) 18S is an appropriate housekeeping gene for in vitro hypoxia experiments. British J. of Cancer 103, 590.
-
(2010)
British J. of Cancer
, vol.103
, pp. 590
-
-
Span, P.N.1
-
23
-
-
84864131464
-
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2
-
PRABHAKAR NR, SEMENZA GL (2012) Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2. Physiol. Rev. 92:967-1003.
-
(2012)
Physiol. Rev
, vol.92
, pp. 967-1003
-
-
Prabhakar, N.R.1
Semenza, G.L.2
-
24
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redoxsensitive stabilization of its alpha subunit
-
HUANG LE, ARANY Z, LIVINGSTON DM, BUNN HF (1996) Activation of hypoxia-inducible transcription factor depends primarily upon redoxsensitive stabilization of its alpha subunit. J. Biol. Chem. 271:32253-32259.
-
(2003)
J. Biol. Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
25
-
-
0035107088
-
Chronic hypoxia attenuates resting and exercise-induced VEGF, flt-1, and flk-1 mRNA levels in skeletal muscle
-
OLFERT M, BREEN EC, MATHIEU-COSTELLO O, WAGNER PD (2001) Chronic hypoxia attenuates resting and exercise-induced VEGF, flt-1, and flk-1 mRNA levels in skeletal muscle. J. Appl. Physiol 90:1532-1538.
-
(2001)
J. Appl. Physiol
, vol.90
, pp. 1532-1538
-
-
Olfert, M.1
Breen, E.C.2
Mathieu-Costello, O.3
Wagner, P.D.4
-
26
-
-
38749106115
-
Hypoxia-inducible Factor-1 Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion
-
PAGÉ EL, CHAN DA, GIACCIA AJ, LEVINE M, and RICHARD DE (2008). Hypoxia-inducible Factor-1 Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion. Mol. Biol. of the Cell 19:86-94.
-
(2008)
Mol. Biol. of the Cell
, vol.19
, pp. 86-94
-
-
Pagé, E.L.1
Chan, D.A.2
Giaccia, A.J.3
Levine, M.4
Richard, D.E.5
-
27
-
-
46049101008
-
Relative quantification
-
In DORAK MT (ed) Real-time PCR (Advanced Methods)
-
PFAFFL MW (2006) Relative quantification. In DORAK MT (ed) Real-time PCR (Advanced Methods). International University. pp 63-82.
-
(2006)
International University
, pp. 63-82
-
-
Pfaffl, M.W.1
-
28
-
-
84878634927
-
Activation of Hypoxia-Inducible Factor-1 in Pulmonary Arterial Smooth Muscle Cells by Endothelin-1
-
[Epub ahead of print]
-
PISARCIK S, MAYLOR J, LU W, YUN X, UNDEM C, SYLVESTER JT, SEMENZA GL, SHIMODA LA (2013). Activation of Hypoxia-Inducible Factor-1 in Pulmonary Arterial Smooth Muscle Cells by Endothelin-1. Am J Physiol Lung Cell Mol Physiol. [Epub ahead of print].
-
(2013)
Am J Physiol Lung Cell Mol Physiol
-
-
Pisarcik, S.1
Maylor, J.2
Lu, W.3
Yun, X.4
Undem, C.5
Sylvester, J.T.6
Semenza, G.L.7
Shimoda, L.A.8
-
29
-
-
34250617887
-
Molecular cloning, characterization and expression of two hypoxia-inducible factor alpha subunits, HIF1a and HIF-2a
-
in a hypoxiatolerant marine teleost, Atlantic croaker (Micropogonias undulatus)
-
RAHMAN, MS, THOMAS P (2007) Molecular cloning, characterization and expression of two hypoxia-inducible factor alpha subunits, HIF1a and HIF-2a, in a hypoxiatolerant marine teleost, Atlantic croaker (Micropogonias undulatus). Gene 396: 273-282.
-
(2007)
Gene
, vol.396
, pp. 273-282
-
-
Rahman, M.S.1
Thomas, P.2
-
30
-
-
79953712964
-
Interstitial pressure and lung oedema in chronic hypoxia
-
RIVOLTA I, LUCCHINI V, ROCCHETTI M, KOLAR F, PALAZZO F, ZAZA A, MISEROCCHI G (2011) Interstitial pressure and lung oedema in chronic hypoxia. Eur. Respir. J. 37:943-9.
-
(2011)
Eur. Respir. J
, vol.37
, pp. 943-949
-
-
Rivolta, I.1
Lucchini, V.2
Rocchetti, M.3
Kolar, F.4
Palazzo, F.5
Zaza, A.6
Miserocchi, G.7
-
31
-
-
0027768558
-
Effect of intermittent chronic exposure to hypoxia on feeding behaviour of rats
-
SINGH SB, SELVAMURTHY W, (1993) Effect of intermittent chronic exposure to hypoxia on feeding behaviour of rats. Int J Biometeorol. 37:200-2.
-
(1993)
Int J Biometeorol
, vol.37
, pp. 200-202
-
-
Singh, S.B.1
Selvamurthy, W.2
-
32
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
SHWEIKI D, ITIN A, SOFFER D, KESHET E (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 359:843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
33
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
STROKA DM, BURKHARDT T, DESBAILLETS I, WENGER RH, NEIL DA, BAUER C, GASSMANN M, CANDINAS D (2001) HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J. 15:2445-2453.
-
(2001)
FASEB J
, vol.15
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkhardt, T.2
Desbaillets, I.3
Wenger, R.H.4
Neil, D.A.5
Bauer, C.6
Gassmann, M.7
Candinas, D.8
-
34
-
-
0033870281
-
The Expression and Distribution of the Hypoxia- Inducible Factors HIF-1a and HIF-2a in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
-
TALKS KL, TURLEY H, GATTER KC, MAXWELL PH, PUGH CW, RATCLIFFE PJ, and HARRIS AL (2000). The Expression and Distribution of the Hypoxia- Inducible Factors HIF-1a and HIF-2a in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages. Am. J of Pathology, 157:411-421.
-
(2000)
Am. J of Pathology
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
35
-
-
84863589085
-
Hypoxia-inducible factor (HIF1α) gene expression in human shock states
-
TEXTORIS J, BEAUFILS N, QUINTANA G, LASSOUD AB, ZIELESKIEWICZ L, WIRAMUS S, BLASCO V, LESAVRE N, MARTIN C, GABERT J, LEONE M (2012) Hypoxia-inducible factor (HIF1α) gene expression in human shock states. Crit Care. 16:R120.
-
(2012)
Crit Care
, vol.16
-
-
Textoris, J.1
Beaufils, N.2
Quintana, G.3
Lassoud, A.B.4
Zieleskiewicz, L.5
Wiramus, S.6
Blasco, V.7
Lesavre, N.8
Martin, C.9
Gabert, J.10
Leone, M.11
-
36
-
-
0037315337
-
Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs
-
WIESENER MS, JÜRGENSEN JS, ROSENBERGER C, SCHOLZE CK, HÖRSTRUP JH, WARNECKE C, MANDRIOTA S, BECHMANN I, FREI UA, PUGH CW, RATCLIFFE PJ, BACHMANN S, MAXWELL PH, ECKARDT KU (2003) Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J. 17:271-273.
-
(2003)
FASEB J
, vol.17
, pp. 271-273
-
-
Wiesener, M.S.1
Jürgensen, J.S.2
Rosenberger, C.3
Scholze, C.K.4
Hörstrup, J.H.5
Warnecke, C.6
Mandriota, S.7
Bechmann, I.8
Frei, U.A.9
Pugh, C.W.10
Ratcliffe, P.J.11
Bachmann, S.12
Maxwell, P.H.13
Eckardt, K.U.14
-
37
-
-
0041523923
-
Decay rates of human mRNAs: Correlation with functional characteristics and sequence attributes
-
YANG E, VAN NIMWEGEN E, ZAVOLAN M, RAJEWSKY N, SCHROEDER M, MAGNASCO M, DARNELL JE JR (2003) Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res 13:1863-1872.
-
(2003)
Genome Res
, vol.13
, pp. 1863-1872
-
-
Yang, E.1
Van Nimwegen, E.2
Zavolan, M.3
Rajewsky, N.4
Schroeder, M.5
Magnasco, M.6
Darnell Jr., J.E.7
-
38
-
-
0031753986
-
Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung
-
YU AY, FRID MG, SHIMODA LA, WIENER CM, STENMARK K, SEMENZA GL (1998) Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung. Am. J. Physiol 275:L818-L826.
-
(1998)
Am. J. Physiol
, vol.275
-
-
Yu, A.Y.1
Frid, M.G.2
Shimoda, L.A.3
Wiener, C.M.4
Stenmark, K.5
Semenza, G.L.6
-
39
-
-
32644469701
-
Realtime RT-PCR quantitative assays and postmortem degradation profiles of erythropoietin, vascular endothelial growth factor and hypoxiainducible factor 1 alpha mRNA transcripts in forensic autopsy materials
-
ZHAO D, ZHU BL, ISHIKAWA T, QUAN L, LI DR, MAEDA H (2006) Realtime RT-PCR quantitative assays and postmortem degradation profiles of erythropoietin, vascular endothelial growth factor and hypoxiainducible factor 1 alpha mRNA transcripts in forensic autopsy materials. Leg. Med. 8:132-136.
-
(2006)
Leg. Med
, vol.8
, pp. 132-136
-
-
Zhao, D.1
Zhu, B.L.2
Ishikawa, T.3
Quan, L.4
Li, D.R.5
Maeda, H.6
|