-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0031768588
-
Efficacy of exogenous recombinant murine leptin in lean and obese 10- to 12-mo-old female CD-1 mice
-
Pelleymounter M.A., Cullen M.J., Healy D., Hecht R., Winters D., McCaleb M. Efficacy of exogenous recombinant murine leptin in lean and obese 10- to 12-mo-old female CD-1 mice. Am J Physiol 1998, 275:R950-R959.
-
(1998)
Am J Physiol
, vol.275
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Healy, D.3
Hecht, R.4
Winters, D.5
McCaleb, M.6
-
3
-
-
0032456318
-
Metabolic responses to intracerebroventricular leptin and restricted feeding
-
Wang T., Hartzell D.L., Rose B.S., Flatt W.P., Hulsey M.G., Menon N.K., et al. Metabolic responses to intracerebroventricular leptin and restricted feeding. Physiol Behav 1999, 65:839-848.
-
(1999)
Physiol Behav
, vol.65
, pp. 839-848
-
-
Wang, T.1
Hartzell, D.L.2
Rose, B.S.3
Flatt, W.P.4
Hulsey, M.G.5
Menon, N.K.6
-
4
-
-
44949163013
-
Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms
-
Buettner C., Muse E.D., Cheng A., Chen L., Scherer T., Pocai A., et al. Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms. Nat Med 2008, 14:667-675.
-
(2008)
Nat Med
, vol.14
, pp. 667-675
-
-
Buettner, C.1
Muse, E.D.2
Cheng, A.3
Chen, L.4
Scherer, T.5
Pocai, A.6
-
5
-
-
0037214387
-
Method of leptin dosing, strain, and group housing influence leptin sensitivity in high-fat-fed weanling mice
-
Bowen H., Mitchell T.D., Harris R.B. Method of leptin dosing, strain, and group housing influence leptin sensitivity in high-fat-fed weanling mice. Am J Physiol Regul Integr Comp Physiol 2003, 284:R87-R100.
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.284
-
-
Bowen, H.1
Mitchell, T.D.2
Harris, R.B.3
-
6
-
-
33845395503
-
Effects of central or peripheral leptin administration on norepinephrine turnover in defined fat depots
-
Penn D.M., Jordan L.C., Kelso E.W., Davenport J.E., Harris R.B. Effects of central or peripheral leptin administration on norepinephrine turnover in defined fat depots. Am J Physiol Regul Integr Comp Physiol 2006, 291:R1613-R1621.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
-
-
Penn, D.M.1
Jordan, L.C.2
Kelso, E.W.3
Davenport, J.E.4
Harris, R.B.5
-
7
-
-
17844389670
-
The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity
-
Coppari R., Ichinose M., Lee C.E., Pullen A.E., Kenny C.D., McGovern R.A., et al. The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metab 2005, 1:63-72.
-
(2005)
Cell Metab
, vol.1
, pp. 63-72
-
-
Coppari, R.1
Ichinose, M.2
Lee, C.E.3
Pullen, A.E.4
Kenny, C.D.5
McGovern, R.A.6
-
8
-
-
79960190012
-
Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons
-
Vong L., Ye C., Yang Z., Choi B., Chua S., Lowell B.B. Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Neuron 2011, 71:142-154.
-
(2011)
Neuron
, vol.71
, pp. 142-154
-
-
Vong, L.1
Ye, C.2
Yang, Z.3
Choi, B.4
Chua, S.5
Lowell, B.B.6
-
9
-
-
41549111593
-
Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion
-
van de Wall E., Leshan R., Xu A.W., Balthasar N., Coppari R., Liu S.M., et al. Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology 2008, 149:1773-1785.
-
(2008)
Endocrinology
, vol.149
, pp. 1773-1785
-
-
van de Wall, E.1
Leshan, R.2
Xu, A.W.3
Balthasar, N.4
Coppari, R.5
Liu, S.M.6
-
10
-
-
30644473109
-
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
-
Dhillon H., Zigman J.M., Ye C., Lee C.E., McGovern R.A., Tang V., et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 2006, 49:191-203.
-
(2006)
Neuron
, vol.49
, pp. 191-203
-
-
Dhillon, H.1
Zigman, J.M.2
Ye, C.3
Lee, C.E.4
McGovern, R.A.5
Tang, V.6
-
11
-
-
63849112609
-
Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors
-
Skibicka K.P., Grill H.J. Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors. Endocrinology 2009, 150:1705-1711.
-
(2009)
Endocrinology
, vol.150
, pp. 1705-1711
-
-
Skibicka, K.P.1
Grill, H.J.2
-
12
-
-
0033744128
-
Leptin rapidly inhibits hypothalamic neuropeptide Y secretion and stimulates corticotropin-releasing hormone secretion in adrenalectomized mice
-
Jang M., Mistry A., Swick A.G., Romsos D.R. Leptin rapidly inhibits hypothalamic neuropeptide Y secretion and stimulates corticotropin-releasing hormone secretion in adrenalectomized mice. J Nutr 2000, 130:2813-2820.
-
(2000)
J Nutr
, vol.130
, pp. 2813-2820
-
-
Jang, M.1
Mistry, A.2
Swick, A.G.3
Romsos, D.R.4
-
13
-
-
0030775971
-
Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus
-
Schwartz M.W., Seeley R.J., Woods S.C., Weigle D.S., Campfield L.A., Burn P., et al. Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes 1997, 46:2119-2123.
-
(1997)
Diabetes
, vol.46
, pp. 2119-2123
-
-
Schwartz, M.W.1
Seeley, R.J.2
Woods, S.C.3
Weigle, D.S.4
Campfield, L.A.5
Burn, P.6
-
14
-
-
0032492893
-
Hypothalamic CART is a new anorectic peptide regulated by leptin
-
Kristensen P., Judge M.E., Thim L., Ribel U., Christjansen K.N., Wulff B.S., et al. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 1998, 393:72-76.
-
(1998)
Nature
, vol.393
, pp. 72-76
-
-
Kristensen, P.1
Judge, M.E.2
Thim, L.3
Ribel, U.4
Christjansen, K.N.5
Wulff, B.S.6
-
15
-
-
0035120192
-
Leptin amplifies the feeding inhibition and neural activation arising from a gastric nutrient preload
-
Emond M., Ladenheim E.E., Schwartz G.J., Moran T.H. Leptin amplifies the feeding inhibition and neural activation arising from a gastric nutrient preload. Physiol Behav 2001, 72:123-128.
-
(2001)
Physiol Behav
, vol.72
, pp. 123-128
-
-
Emond, M.1
Ladenheim, E.E.2
Schwartz, G.J.3
Moran, T.H.4
-
17
-
-
34748864673
-
Leptin responsiveness in chronically decerebrate rats
-
Harris R.B., Bartness T.J., Grill H.J. Leptin responsiveness in chronically decerebrate rats. Endocrinology 2007, 148:4623-4633.
-
(2007)
Endocrinology
, vol.148
, pp. 4623-4633
-
-
Harris, R.B.1
Bartness, T.J.2
Grill, H.J.3
-
18
-
-
84873360376
-
Leptin-induced increase in body fat content of rats
-
Harris R.B. Leptin-induced increase in body fat content of rats. Am J Physiol Endocrinol Metab 2013, 304:E267-E281.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.304
-
-
Harris, R.B.1
-
19
-
-
33947601443
-
Preparation of leptin antagonists by site-directed mutagenesis of human, ovine, rat, and mouse leptin's site III: implications on blocking undesired leptin action in vivo
-
Solomon G., Niv-Spector L., Gonen-Berger D., Callebaut I., Djiane J., Gertler A. Preparation of leptin antagonists by site-directed mutagenesis of human, ovine, rat, and mouse leptin's site III: implications on blocking undesired leptin action in vivo. Ann N Y Acad Sci 2006, 1091:531-539.
-
(2006)
Ann N Y Acad Sci
, vol.1091
, pp. 531-539
-
-
Solomon, G.1
Niv-Spector, L.2
Gonen-Berger, D.3
Callebaut, I.4
Djiane, J.5
Gertler, A.6
-
20
-
-
34250862302
-
Leptin analog antagonizes leptin effects on food intake and body weight but mimics leptin-induced vagal afferent activation
-
Peters J.H., Simasko S.M., Ritter R.C. Leptin analog antagonizes leptin effects on food intake and body weight but mimics leptin-induced vagal afferent activation. Endocrinology 2007, 148:2878-2885.
-
(2007)
Endocrinology
, vol.148
, pp. 2878-2885
-
-
Peters, J.H.1
Simasko, S.M.2
Ritter, R.C.3
-
22
-
-
57749098701
-
Antagonism of specific corticotropin-releasing factor receptor subtypes selectively modifies weight loss in restrained rats
-
Chotiwat C., Harris R.B. Antagonism of specific corticotropin-releasing factor receptor subtypes selectively modifies weight loss in restrained rats. Am J Physiol Regul Integr Comp Physiol 2008, 295:R1762-R1773.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Chotiwat, C.1
Harris, R.B.2
-
23
-
-
51149086170
-
Antagonism of corticotrophin-releasing factor receptors in the fourth ventricle modifies responses to mild but not restraint stress
-
Miragaya J.R., Harris R.B. Antagonism of corticotrophin-releasing factor receptors in the fourth ventricle modifies responses to mild but not restraint stress. Am J Physiol Regul Integr Comp Physiol 2008, 295:R404-R416.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Miragaya, J.R.1
Harris, R.B.2
-
24
-
-
84862841608
-
Sympathetic denervation of one white fat depot changes norepinephrine content and turnover in intact white and brown fat depots
-
Harris R.B. Sympathetic denervation of one white fat depot changes norepinephrine content and turnover in intact white and brown fat depots. Obesity (Silver Spring) 2012, 20:1355-1364.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1355-1364
-
-
Harris, R.B.1
-
25
-
-
0025776813
-
Growth measurements in Sprague-Dawley rats fed diets of very low fat concentration
-
Harris R.B. Growth measurements in Sprague-Dawley rats fed diets of very low fat concentration. J Nutr 1991, 121:1075-1080.
-
(1991)
J Nutr
, vol.121
, pp. 1075-1080
-
-
Harris, R.B.1
-
26
-
-
80053052166
-
The relation between dietary fructose, dietary fat and leptin responsiveness in rats
-
Haring S.J., Harris R.B. The relation between dietary fructose, dietary fat and leptin responsiveness in rats. Physiol Behav 2011, 104:914-922.
-
(2011)
Physiol Behav
, vol.104
, pp. 914-922
-
-
Haring, S.J.1
Harris, R.B.2
-
27
-
-
84865743048
-
Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives
-
Even P.C., Nadkarni N.A. Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives. Am J Physiol Regul Integr Comp Physiol 2012, 303:R459-R476.
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.303
-
-
Even, P.C.1
Nadkarni, N.A.2
-
29
-
-
0033944956
-
Partial saturation and regional variation in the blood-to-brain transport of leptin in normal weight mice
-
Banks W.A., Clever C.M., Farrell C.L. Partial saturation and regional variation in the blood-to-brain transport of leptin in normal weight mice. Am J Physiol Endocrinol Metab 2000, 278:E1158-E1165.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.278
-
-
Banks, W.A.1
Clever, C.M.2
Farrell, C.L.3
-
30
-
-
0030885398
-
Entrainment of the diurnal rhythm of plasma leptin to meal timing
-
Schoeller D.A., Cella L.K., Sinha M.K., Caro J.F. Entrainment of the diurnal rhythm of plasma leptin to meal timing. J Clin Invest 1997, 100:1882-1887.
-
(1997)
J Clin Invest
, vol.100
, pp. 1882-1887
-
-
Schoeller, D.A.1
Cella, L.K.2
Sinha, M.K.3
Caro, J.F.4
-
31
-
-
84874236315
-
Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance
-
Olofsson L.E., Unger E.K., Cheung C.C., Xu A.W. Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance. Proc Natl Acad Sci U S A 2013, 110:E697-E706.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
-
-
Olofsson, L.E.1
Unger, E.K.2
Cheung, C.C.3
Xu, A.W.4
-
32
-
-
84868576867
-
Evaluating the potential for rostral diffusion in the cerebral ventricles using angiotensin II-induced drinking in rats
-
Daniels D., Marshall A. Evaluating the potential for rostral diffusion in the cerebral ventricles using angiotensin II-induced drinking in rats. Brain Res 2012, 1486:62-67.
-
(2012)
Brain Res
, vol.1486
, pp. 62-67
-
-
Daniels, D.1
Marshall, A.2
-
33
-
-
0037012473
-
Effects of continuous lumbar intrathecal infusion of leptin in rats on weight regulation
-
Yaksh T.L., Scott B., LeBel C.L. Effects of continuous lumbar intrathecal infusion of leptin in rats on weight regulation. Neuroscience 2002, 110:703-710.
-
(2002)
Neuroscience
, vol.110
, pp. 703-710
-
-
Yaksh, T.L.1
Scott, B.2
LeBel, C.L.3
-
34
-
-
77950231554
-
Increased hypothalamic signal transducer and activator of transcription 3 phosphorylation after hindbrain leptin injection
-
Ruiter M., Duffy P., Simasko S., Ritter R.C. Increased hypothalamic signal transducer and activator of transcription 3 phosphorylation after hindbrain leptin injection. Endocrinology 2010, 151:1509-1519.
-
(2010)
Endocrinology
, vol.151
, pp. 1509-1519
-
-
Ruiter, M.1
Duffy, P.2
Simasko, S.3
Ritter, R.C.4
-
35
-
-
70350541138
-
STAT3 as a central regulator of tumor metastases
-
Devarajan E., Huang S. STAT3 as a central regulator of tumor metastases. Curr Mol Med 2009, 9:626-633.
-
(2009)
Curr Mol Med
, vol.9
, pp. 626-633
-
-
Devarajan, E.1
Huang, S.2
-
36
-
-
77950574396
-
Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors
-
Kim K.S., Yoon Y.R., Lee H.J., Yoon S., Kim S.Y., Shin S.W., et al. Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem 2010, 285:8905-8917.
-
(2010)
J Biol Chem
, vol.285
, pp. 8905-8917
-
-
Kim, K.S.1
Yoon, Y.R.2
Lee, H.J.3
Yoon, S.4
Kim, S.Y.5
Shin, S.W.6
-
37
-
-
84863012554
-
The Jak/STAT pathway is involved in synaptic plasticity
-
Nicolas C.S., Peineau S., Amici M., Csaba Z., Fafouri A., Javalet C., et al. The Jak/STAT pathway is involved in synaptic plasticity. Neuron 2012, 73:374-390.
-
(2012)
Neuron
, vol.73
, pp. 374-390
-
-
Nicolas, C.S.1
Peineau, S.2
Amici, M.3
Csaba, Z.4
Fafouri, A.5
Javalet, C.6
-
38
-
-
0007500186
-
Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats
-
Seeley R.J., van Dijk G., Campfield L.A., Smith F.J., Burn P., Nelligan J.A., et al. Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. Horm Metab Res 1996, 28:664-668.
-
(1996)
Horm Metab Res
, vol.28
, pp. 664-668
-
-
Seeley, R.J.1
van Dijk, G.2
Campfield, L.A.3
Smith, F.J.4
Burn, P.5
Nelligan, J.A.6
-
39
-
-
84871005992
-
Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner
-
Zhao S., Kanoski S.E., Yan J., Grill H.J., Hayes M.R. Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner. Int J Obes (Lond) 2012, 36:1522-1528.
-
(2012)
Int J Obes (Lond)
, vol.36
, pp. 1522-1528
-
-
Zhao, S.1
Kanoski, S.E.2
Yan, J.3
Grill, H.J.4
Hayes, M.R.5
-
40
-
-
9244219587
-
Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
-
Munzberg H., Flier J.S., Bjorbaek C. Region-specific leptin resistance within the hypothalamus of diet-induced obese mice. Endocrinology 2004, 145:4880-4889.
-
(2004)
Endocrinology
, vol.145
, pp. 4880-4889
-
-
Munzberg, H.1
Flier, J.S.2
Bjorbaek, C.3
-
41
-
-
0036798083
-
Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neurones
-
Sahu A. Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neurones. J Neuroendocrinol 2002, 14:796-804.
-
(2002)
J Neuroendocrinol
, vol.14
, pp. 796-804
-
-
Sahu, A.1
-
42
-
-
0042922605
-
Leptin signaling in the hypothalamus during chronic central leptin infusion
-
Pal R., Sahu A. Leptin signaling in the hypothalamus during chronic central leptin infusion. Endocrinology 2003, 144:3789-3798.
-
(2003)
Endocrinology
, vol.144
, pp. 3789-3798
-
-
Pal, R.1
Sahu, A.2
-
44
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima R.S., Prabakaran D., Mantzoros C., Qu D., Lowell B., Maratos-Flier E., et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996, 382:250-252.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
-
45
-
-
0030759687
-
Leptin increases uncoupling protein expression and energy expenditure
-
Scarpace P.J., Matheny M., Pollock B.H., Tumer N. Leptin increases uncoupling protein expression and energy expenditure. Am J Physiol 1997, 273:E226-E230.
-
(1997)
Am J Physiol
, vol.273
-
-
Scarpace, P.J.1
Matheny, M.2
Pollock, B.H.3
Tumer, N.4
-
46
-
-
0031766974
-
Fate of leptin after intracerebroventricular injection into the mouse brain
-
Maness L.M., Kastin A.J., Farrell C.L., Banks W.A. Fate of leptin after intracerebroventricular injection into the mouse brain. Endocrinology 1998, 139:4556-4562.
-
(1998)
Endocrinology
, vol.139
, pp. 4556-4562
-
-
Maness, L.M.1
Kastin, A.J.2
Farrell, C.L.3
Banks, W.A.4
-
47
-
-
0017124579
-
Glucose metabolism in isolated fat cells: enhanced response of larger adipocytes from older rats to epinephrine and adrenocorticotropin
-
DiGirolamo M., Owens J.L. Glucose metabolism in isolated fat cells: enhanced response of larger adipocytes from older rats to epinephrine and adrenocorticotropin. Horm Metab Res 1976, 8:445-451.
-
(1976)
Horm Metab Res
, vol.8
, pp. 445-451
-
-
DiGirolamo, M.1
Owens, J.L.2
-
48
-
-
52949140814
-
Making insulin-deficient type 1 diabetic rodents thrive without insulin
-
Yu X., Park B.H., Wang M.Y., Wang Z.V., Unger R.H. Making insulin-deficient type 1 diabetic rodents thrive without insulin. Proc Natl Acad Sci U S A 2008, 105:14070-14075.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14070-14075
-
-
Yu, X.1
Park, B.H.2
Wang, M.Y.3
Wang, Z.V.4
Unger, R.H.5
-
49
-
-
77953169464
-
The lipoprivic control of feeding is governed by fat metabolism, not by leptin or adipose depletion
-
Hudson B.D., Emanuel A.J., Wiater M.F., Ritter S. The lipoprivic control of feeding is governed by fat metabolism, not by leptin or adipose depletion. Endocrinology 2010, 151:2087-2096.
-
(2010)
Endocrinology
, vol.151
, pp. 2087-2096
-
-
Hudson, B.D.1
Emanuel, A.J.2
Wiater, M.F.3
Ritter, S.4
-
50
-
-
0033580938
-
Novel form of lipolysis induced by leptin
-
Wang M.Y., Lee Y., Unger R.H. Novel form of lipolysis induced by leptin. J Biol Chem 1999, 274:17541-17544.
-
(1999)
J Biol Chem
, vol.274
, pp. 17541-17544
-
-
Wang, M.Y.1
Lee, Y.2
Unger, R.H.3
-
51
-
-
0035937174
-
Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia
-
Lee Y., Wang M.Y., Kakuma T., Wang Z.W., Babcock E., McCorkle K., et al. Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia. J Biol Chem 2001, 276:5629-5635.
-
(2001)
J Biol Chem
, vol.276
, pp. 5629-5635
-
-
Lee, Y.1
Wang, M.Y.2
Kakuma, T.3
Wang, Z.W.4
Babcock, E.5
McCorkle, K.6
-
52
-
-
0032540098
-
Acute and chronic effects of leptin on glucose utilization in lean mice
-
Harris R.B. Acute and chronic effects of leptin on glucose utilization in lean mice. Biochem Biophys Res Commun 1998, 245:502-509.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 502-509
-
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