Marchantin C: A potential anti-invasion agent in glioma cells

Cancer Biology and Therapy

Volumn 9, Issue 1, 2010, Pages 33-39

  Shen, Jie ^a   Li, Gang ^a   Liu, Qinglin ^a   He, Qiaowei ^a   Gu, Jinhai ^b   Shi, Yanqiu ^c   Lou, Hongxiang ^c  

^a SHANDONG UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

CAM; Glioma; Invasion; MAPK; Marchantin C; PI3K; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; GELATINASE A; MARCHANTIN C; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG; BIBENZYL DERIVATIVE; CATECHOL DERIVATIVE; DIPHENYL ETHER DERIVATIVE; ETHER DERIVATIVE; PROTEIN KINASE B; STAT3 PROTEIN;

ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GLIOMA CELL; HUMAN; HUMAN CELL; BRAIN TUMOR; CANCER INVASION; CELL MOTION; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; EVALUATION; GLIOMA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIBENZYLS; BRAIN NEOPLASMS; CATECHOLS; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ETHERS, CYCLIC; GLIOMA; HUMANS; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PHENYL ETHERS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 75749121314     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.9.1.10279     Document Type: Article

References (26)

1. Senger D, Cairncross JG, Forsyth PA. Long-term survivors of glioblastoma: statistical aberration or important unrecognized molecular subtype? Cancer J 2003; 9:214-21.
2. Giese A, Rief MD, Loo MA, Berens ME. Determinants of human astrocytoma migration. Cancer Res 1994; 54:3897-904.
3. Giese A, Bjerkvig R, Berens ME, Westphal M. Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003; 21:1624-36.
4. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, et al. Cell migration: integrating signals from front to back. Science 2003; 302:1704-9.
5. Schwartner C, Michel C, Stettmaier K, Wagner H, Bors W. Marchantins and related polyphenols from liverwort: physico-chemical studies of their radical-scavenging properties. Free Radic Biol Med 1996; 20:237-44.
6. Asakawa Y, Toyota M, Tori M, Hashimoto T. Chemical structures of macrocyclic bis(bibenzyls) isolated from liverworts (Hepaticae). Spectroscopy 2000; 14:149-75.
7. Niu C, Qu JB, Lou HX. Antifungal bis[bibenzyls] from the Chinese liverwort Marchantia polymorpha L. Chem Biodivers 2006; 3:34-40.
8. Shi YQ, Liao YX, Qu XJ, Yuan HQ, Li S, Qu JB, et al. Marchantin C, a macrocyclic bisbibenzyl, induces apoptosis of human glioma A172 cells. Cancer Lett 2008; 262:173-82.
9. Shi YQ, Zhu CJ, Yuan HQ, Li BQ, Gao J, Qu XJ, et al. Marchantin C, a novel microtubule inhibitor from liverwort with anti-tumor activity both in vivo and in vitro. Cancer Lett 2008.
10. Xing J, Xie C, Qu J, Guo H, Lv B, Lou H. Rapid screening for bisbibenzyls in bryophyte crude extracts using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2007; 21:2467-76.
11. Nabeshima K, Inoue T, Shimao Y, Sameshima T. Matrix metalloproteinases in tumor invasion: role for cell migration. Pathol Int 2002; 52:255-64.
12. Rao JS. Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 2003; 3:489-501.
13. Xie TX, Huang FJ, Aldape KD, Kang SH, Liu M, Gershenwald JE, et al. Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res 2006; 66:3188-96.
14. Zhao Y, Xiao A, Dipierro CG, Abdel-Fattah R, Amos S, Redpath GT, et al. H-Ras increases urokinase expression and cell invasion in genetically modified human astrocytes through Ras/Raf/MEK signaling pathway. Glia 2008; 56:917-24.
15. Kubiatowski T, Jang T, Lachyankar MB, Salmonsen R, Nabi RR, Quesenberry PJ, et al. Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas. J Neurosurg 2001; 95:480-8.
16. Grunstein J, Roberts WG, Mathieu-Costello O, Hanahan D, Johnson RS. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res 1999; 59:1592-8.
17. Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, Vojnovic B, et al. Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res 2001; 21:93-102.
18. Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991; 64:327-36.
19. Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994; 79:185-8.
20. Klagsbrun M, D'Amore PA. Regulators of angiogenesis. Annu Rev Physiol 1991; 53:217-39.
21. Yunker CK, Golembieski W, Lemke N, Schultz CR, Cazacu S, Brodie C, et al. SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion. Int J Cancer 2008; 122:2735-43.
22. Slongo ML, Molena B, Brunati AM, Frasson M, Gardiman M, Carli M, et al. Functional VEGF and VEGF receptors are expressed in human medulloblastomas. Neuro Oncol 2007; 9:384-92.
23. Cantarella G, Risuglia N, Dell'eva R, Lempereur L, Albini A, Pennisi G, et al. TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells. Br J Cancer 2006; 94:1428-35.
24. Lin HL, Chiou SH, Wu CW, Lin WB, Chen LH, Yang YP, et al. Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells. J Pharmacol Exp Ther 2007; 323:365-73.
25. Hussain S, Slevin M, Mesaik MA, Choudhary MI, Elosta AH, Matou S, et al. Cheiradone: a vascular endothelial cell growth factor receptor antagonist. BMC Cell Biol 2008; 9:7.
26. Gong YQ, Fan Y, Wu DZ, Yang H, Hu ZB, Wang ZT. In vivo and in vitro evaluation of erianin, a novel anti-angiogenic agent. Eur J Cancer 2004; 40:1554-65.