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Volumn 30, Issue 4, 2013, Pages 1957-1964

Specific role of JNK in the maintenance of the tumor-initiating capacity of A549 human non-small cell lung cancer cells

Author keywords

Cancer stem cell; JNK; Lung cancer; Tumorigenicity; Xenograft analysis

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

EID: 84882659387     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2655     Document Type: Article
Times cited : (40)

References (34)
  • 1
    • 33847754623 scopus 로고    scopus 로고
    • The JNK signal transduction pathway
    • Weston CR and Davis RJ: The JNK signal transduction pathway. Curr Opin Cell Biol 19: 142-149, 2007.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 142-149
    • Weston, C.R.1    Davis, R.J.2
  • 2
    • 0141723393 scopus 로고    scopus 로고
    • Role of JNK in tumor development
    • Kennedy NJ and Davis RJ: Role of JNK in tumor development. Cell Cycle 2: 199-201, 2003.
    • (2003) Cell Cycle , vol.2 , pp. 199-201
    • Kennedy, N.J.1    Davis, R.J.2
  • 3
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner EF and Nebreda AR: Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer 9: 537-549, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 4
    • 84855896864 scopus 로고    scopus 로고
    • JNK-induced apoptosis, compensatory growth, and cancer stem cells
    • Chen F: JNK-induced apoptosis, compensatory growth, and cancer stem cells. Cancer Res 72: 379-386, 2012.
    • (2012) Cancer Res , vol.72 , pp. 379-386
    • Chen, F.1
  • 5
    • 84882569922 scopus 로고    scopus 로고
    • JNK signaling in the control of the tumor-initiating capacity associated with cancer stem cells
    • (Epub ahead of print). doi: 10.1177/1947601912474892
    • Kitanaka C, Sato A and Okada M: JNK signaling in the control of the tumor-initiating capacity associated with cancer stem cells. Genes Cancer: January 22, 2013 (Epub ahead of print). doi: 10.1177/1947601912474892.
    • (2013) Genes Cancer: January , vol.22
    • Kitanaka, C.1    Sato, A.2    Okada, M.3
  • 6
    • 84864132864 scopus 로고    scopus 로고
    • Targeting JNK for therapeutic depletion of stem-like glioblastoma cells
    • Matsuda K, Sato A, Okada M, et al: Targeting JNK for therapeutic depletion of stem-like glioblastoma cells. Sci Rep 2: 516, 2012.
    • (2012) Sci Rep , vol.2 , pp. 516
    • Matsuda, K.1    Sato, A.2    Okada, M.3
  • 7
    • 84869093860 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells
    • Yoon CH, Kim MJ, Kim RK, et al: c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells. Oncogene 31: 4655-4666, 2012.
    • (2012) Oncogene , vol.31 , pp. 4655-4666
    • Yoon, C.H.1    Kim, M.J.2    Kim, R.K.3
  • 8
    • 84860873820 scopus 로고    scopus 로고
    • The role of cancer stem cells in relapse of solid tumors
    • Yu Y, Ramena G and Elble RC: The role of cancer stem cells in relapse of solid tumors. Front Biosci 4: 1528-1541, 2012.
    • (2012) Front Biosci , vol.4 , pp. 1528-1541
    • Yu, Y.1    Ramena, G.2    Elble, R.C.3
  • 9
    • 84860879245 scopus 로고    scopus 로고
    • Cancer stem cells and resistance to chemo and radio therapy
    • Malik B and Nie D: Cancer stem cells and resistance to chemo and radio therapy. Front Biosci 4: 2142-2149, 2012.
    • (2012) Front Biosci , vol.4 , pp. 2142-2149
    • Malik, B.1    Nie, D.2
  • 12
    • 42349100068 scopus 로고    scopus 로고
    • Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas
    • Li JY, Wang H, May S, et al: Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas. J Neurooncol 88: 11-17, 2008.
    • (2008) J Neurooncol , vol.88 , pp. 11-17
    • Li, J.Y.1    Wang, H.2    May, S.3
  • 13
    • 18544372157 scopus 로고    scopus 로고
    • Elevated JNK activation contributes to the pathogenesis of human brain tumors
    • Antonyak MA, Kenyon LC, Godwin AK, et al: Elevated JNK activation contributes to the pathogenesis of human brain tumors. Oncogene 21: 5038-5046, 2002.
    • (2002) Oncogene , vol.21 , pp. 5038-5046
    • Antonyak, M.A.1    Kenyon, L.C.2    Godwin, A.K.3
  • 14
    • 0037224587 scopus 로고    scopus 로고
    • Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors
    • Tsuiki H, Tnani M, Okamoto I, et al: Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors. Cancer Res 63: 250-255, 2003.
    • (2003) Cancer Res , vol.63 , pp. 250-255
    • Tsuiki, H.1    Tnani, M.2    Okamoto, I.3
  • 15
    • 33750570891 scopus 로고    scopus 로고
    • C-Jun NH2-terminal kinase 2α2 promotes the tumorigenicity of human glioblastoma cells
    • Cui J, Han SY, Wang C, et al: c-Jun NH2-terminal kinase 2α2 promotes the tumorigenicity of human glioblastoma cells. Cancer Res 66: 10024-10031, 2006.
    • (2006) Cancer Res , vol.66 , pp. 10024-10031
    • Cui, J.1    Han, S.Y.2    Wang, C.3
  • 16
    • 34247357465 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells
    • Khatlani TS, Wislez M, Sun M, et al: c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells. Oncogene 26: 2658-2666, 2007.
    • (2007) Oncogene , vol.26 , pp. 2658-2666
    • Khatlani, T.S.1    Wislez, M.2    Sun, M.3
  • 17
    • 78651389661 scopus 로고    scopus 로고
    • The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis
    • Nitta RT, Del Vecchio CA, Chu AH, Mitra SS, Godwin AK and Wong AJ: The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis. Oncogene 30: 234-244, 2011.
    • (2011) Oncogene , vol.30 , pp. 234-244
    • Nitta, R.T.1    Del Vecchio, C.A.2    Chu, A.H.3    Mitra, S.S.4    Godwin, A.K.5    Wong, A.J.6
  • 18
    • 75749148308 scopus 로고    scopus 로고
    • Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species
    • Lee JJ, Lee JH, Ko YG, Hong SI and Lee JS: Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species. Oncogene 29: 561-575, 2010.
    • (2010) Oncogene , vol.29 , pp. 561-575
    • Lee, J.J.1    Lee, J.H.2    Ko, Y.G.3    Hong, S.I.4    Lee, J.S.5
  • 19
    • 0028142369 scopus 로고
    • Modulation of intrinsic in vitro resistance to carboplatin by edatrexate in the A549 human nonsmall cell lung cancer cell line
    • Perez EA, Hack FM, Fletcher TS and Chou TC: Modulation of intrinsic in vitro resistance to carboplatin by edatrexate in the A549 human nonsmall cell lung cancer cell line. Oncol Res 6: 151-156, 1994.
    • (1994) Oncol Res , vol.6 , pp. 151-156
    • Perez, E.A.1    Hack, F.M.2    Fletcher, T.S.3    Chou, T.C.4
  • 20
    • 33745198882 scopus 로고    scopus 로고
    • Chemotherapy resistance of glioblastoma stem cells
    • Eramo A, Ricci-Vitiani L, Zeuner A, et al: Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 13: 1238-1241, 2006.
    • (2006) Cell Death Differ , vol.13 , pp. 1238-1241
    • Eramo, A.1    Ricci-Vitiani, L.2    Zeuner, A.3
  • 21
    • 39449088496 scopus 로고    scopus 로고
    • Identification and expansion of the tumorigenic lung cancer stem cell population
    • Eramo A, Lotti F, Sette G, et al: Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ 15: 504-514, 2008.
    • (2008) Cell Death Differ , vol.15 , pp. 504-514
    • Eramo, A.1    Lotti, F.2    Sette, G.3
  • 22
    • 33846095137 scopus 로고    scopus 로고
    • Identification and expansion of human colon cancer-initiating cells
    • Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al: Identification and expansion of human colon cancer-initiating cells. Nature 445: 111-115, 2007.
    • (2007) Nature , vol.445 , pp. 111-115
    • Ricci-Vitiani, L.1    Lombardi, D.G.2    Pilozzi, E.3
  • 23
    • 84873024287 scopus 로고    scopus 로고
    • Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK
    • Sato A, Sunayama J, Okada M, et al: Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK. Stem Cells Transl Med 1: 811-824, 2012.
    • (2012) Stem Cells Transl Med , vol.1 , pp. 811-824
    • Sato, A.1    Sunayama, J.2    Okada, M.3
  • 24
    • 0035923665 scopus 로고    scopus 로고
    • SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
    • Bennett BL, Sasaki DT, Murray BW, et al: SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 98: 13681-13686, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13681-13686
    • Bennett, B.L.1    Sasaki, D.T.2    Murray, B.W.3
  • 25
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270: 1326-1331, 1995.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 26
    • 54249119561 scopus 로고    scopus 로고
    • JNK signaling in apoptosis
    • Dhanasekaran DN and Reddy EP: JNK signaling in apoptosis. Oncogene 27: 6245-6251, 2008.
    • (2008) Oncogene , vol.27 , pp. 6245-6251
    • Dhanasekaran, D.N.1    Reddy, E.P.2
  • 27
    • 0031746455 scopus 로고    scopus 로고
    • The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis
    • Verheij M, Ruiter GA, Zerp SF, et al: The role of the stress-activated protein kinase (SAPK/JNK) signaling pathway in radiation-induced apoptosis. Radiother Oncol 47: 225-232, 1998.
    • (1998) Radiother Oncol , vol.47 , pp. 225-232
    • Verheij, M.1    Ruiter, G.A.2    Zerp, S.F.3
  • 28
    • 0035735754 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy
    • Fan M and Chambers TC: Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy. Drug Resist Updat 4: 253-267, 2001.
    • (2001) Drug Resist Updat , vol.4 , pp. 253-267
    • Fan, M.1    Chambers, T.C.2
  • 29
    • 79953778211 scopus 로고    scopus 로고
    • Requirement of c-Jun NH2-terminal kinase for Ras-initiated tumor formation
    • Cellurale C, Sabio G, Kennedy NJ, et al: Requirement of c-Jun NH2-terminal kinase for Ras-initiated tumor formation. Mol Cell Biol 31: 1565-1576, 2011.
    • (2011) Mol Cell Biol , vol.31 , pp. 1565-1576
    • Cellurale, C.1    Sabio, G.2    Kennedy, N.J.3
  • 30
    • 0035893252 scopus 로고    scopus 로고
    • Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
    • Jackson EL, Willis N, Mercer K, et al: Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 15: 3243-3248, 2001.
    • (2001) Genes Dev , vol.15 , pp. 3243-3248
    • Jackson, E.L.1    Willis, N.2    Mercer, K.3
  • 31
    • 0030751333 scopus 로고    scopus 로고
    • Occurrence of ras mutations in human lung cancer
    • Vachtenheim J: Occurrence of ras mutations in human lung cancer. Minireview. Neoplasma 44: 145-149, 1997.
    • (1997) Minireview. Neoplasma , vol.44 , pp. 145-149
    • Vachtenheim, J.1
  • 32
    • 84255161043 scopus 로고    scopus 로고
    • Pulmonary adenocarcinoma: A renewed entity in 2011
    • Kadara H, Kabbout M and Wistuba II: Pulmonary adenocarcinoma: a renewed entity in 2011. Respirology 17: 50-65, 2012.
    • (2012) Respirology , vol.17 , pp. 50-65
    • Kadara, H.1    Kabbout, M.2    Wistuba, I.I.3
  • 33
    • 79952207890 scopus 로고    scopus 로고
    • KRAS-mutated non-small cell lung cancer cells are responsive to either co-treatment with erlotinib or gefitinib and histone deacetylase inhibitors or single treatment with lapatinib
    • Kurtze I, Sonnemann J and Beck JF: KRAS-mutated non-small cell lung cancer cells are responsive to either co-treatment with erlotinib or gefitinib and histone deacetylase inhibitors or single treatment with lapatinib. Oncol Rep 25: 1021-1029, 2011.
    • (2011) Oncol Rep , vol.25 , pp. 1021-1029
    • Kurtze, I.1    Sonnemann, J.2    Beck, J.F.3
  • 34
    • 1542469696 scopus 로고    scopus 로고
    • K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: Possible contribution to non-invasive expansion of lung adenocarcinoma
    • Okudela K, Hayashi H, Ito T, et al: K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma. Am J Pathol 164: 91-100, 2004.
    • (2004) Am J Pathol , vol.164 , pp. 91-100
    • Okudela, K.1    Hayashi, H.2    Ito, T.3


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