Flexibility is a mechanical determinant of antimicrobial activity for amphipathic cationic α-helical antimicrobial peptides

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 11, 2013, Pages 2479-2486

  Liu, Li ^a   Fang, Ying ^a   Wu, Jianhua ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

AMP; Antimicrobial activity; B factor; Flexibility; Structure activity relationship

Indexed keywords

ALPHA HELICAL ANTIMICROBIAL PEPTIDE; AMPHOPHILE; ANTIMICROBIAL CATIONIC PEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

AMINO ACID FLEXIBILITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; CELL STRESS; DRUG BINDING; DRUG STRUCTURE; DRUG TARGETING; ESCHERICHIA COLI; FLEXURAL RIGIDITY; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN TARGETING; RIGIDITY; STRUCTURE ACTIVITY RELATION; TENSILE STRENGTH; YOUNG MODULUS;

AMP; ANTIMICROBIAL ACTIVITY; B-FACTOR; FLEXIBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

ANTIMICROBIAL CATIONIC PEPTIDES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84882587595     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2013.06.017     Document Type: Article

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