A rigidity-enhanced antimicrobial activity: A case for linear cationic α-helical peptide HP(2-20) and its four analogues

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Liu, Li ^a   Fang, Ying ^a   Huang, Qingsheng ^a,b   Wu, Jianhua ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HELICAL PEPTIDE A1; ALPHA HELICAL PEPTIDE A2; ALPHA HELICAL PEPTIDE A3; ALPHA HELICAL PEPTIDE A5; ALPHA HELICAL PEPTIDE[2-20]; PEPTIDE DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; HP (2 20) PROTEIN, HELICOBACTER PYLORI; HP (2-20) PROTEIN, HELICOBACTER PYLORI; PEPTIDE FRAGMENT;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DENATURATION; ESCHERICHIA COLI; HYDROGEN BOND; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DYNAMICS; NONHUMAN; RIGIDITY; SIMULATION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; TENSILE STRENGTH; YOUNG MODULUS; BIOMECHANICS; CELL MEMBRANE PERMEABILITY; CHEMISTRY; ISOLATION AND PURIFICATION;

HELICOBACTER PYLORI;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL PROTEINS; BIOMECHANICS; CELL MEMBRANE PERMEABILITY; HYDROGEN BONDING; PEPTIDE FRAGMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TENSILE STRENGTH;

EID: 79551572746     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016441     Document Type: Article

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