메뉴 건너뛰기




Volumn , Issue , 2016, Pages 9-20

Cellular Mechanisms Underlying Morphine Analgesic Tolerance and Hyperalgesia

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84882584630     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.3109/9781420089004-5     Document Type: Chapter
Times cited : (1)

References (58)
  • 1
    • 0017189742 scopus 로고
    • Enkephalin evokes biochemical correlates of opiate tolerance and dependence in neuroblastoma x glioma hybrid cells
    • Brandt M, Fischer K, Moroder L, et al. Enkephalin evokes biochemical correlates of opiate tolerance and dependence in neuroblastoma x glioma hybrid cells. FEBS Lett 1976; 68(1): 38-40.
    • (1976) FEBS Lett , vol.68 , Issue.1 , pp. 38-40
    • Brandt, M.1    Fischer, K.2    Moroder, L.3
  • 2
    • 0016749410 scopus 로고
    • Morphine abstinence is associated with increased brain cyclic AMP
    • Collier HO, Francis DL. Morphine abstinence is associated with increased brain cyclic AMP. Nature 1975; 255(5504): 159-162.
    • (1975) Nature , vol.255 , Issue.5504 , pp. 159-162
    • Collier, H.O.1    Francis, D.L.2
  • 3
    • 0011276168 scopus 로고
    • Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance
    • Sharma SK, Klee WA, Nirenberg M. Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance. Proc Natl Acad Sci U S A 1975; 72(8): 3092-3096.
    • (1975) Proc Natl Acad Sci U S A , vol.72 , Issue.8 , pp. 3092-3096
    • Sharma, S.K.1    Klee, W.A.2    Nirenberg, M.3
  • 4
    • 43449124117 scopus 로고    scopus 로고
    • Cellular neuroadaptations to chronic opioids: Tolerance, withdrawal and addiction
    • Christie MJ. Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction. Br J Pharmacol 2008; 154(2): 384-396.
    • (2008) Br J Pharmacol , vol.154 , Issue.2 , pp. 384-396
    • Christie, M.J.1
  • 5
    • 38349103412 scopus 로고    scopus 로고
    • Role of receptor internalization in opioid tolerance and dependence
    • Koch T, Hollt V. Role of receptor internalization in opioid tolerance and dependence. Pharmacol Ther 2008; 117(2): 199-206.
    • (2008) Pharmacol Ther , vol.117 , Issue.2 , pp. 199-206
    • Koch, T.1    Hollt, V.2
  • 6
    • 33749239627 scopus 로고    scopus 로고
    • Tracking the opioid receptors on the way of desensitization
    • Marie N, Aguila B, Allouche S. Tracking the opioid receptors on the way of desensitization. Cell Signal 2006; 18(11): 1815-1833.
    • (2006) Cell Signal , vol.18 , Issue.11 , pp. 1815-1833
    • Marie, N.1    Aguila, B.2    Allouche, S.3
  • 7
    • 37549019374 scopus 로고    scopus 로고
    • The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence
    • Martini L, Whistler JL. The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence. Curr Opin Neurobiol 2007; 17(5): 556-564.
    • (2007) Curr Opin Neurobiol , vol.17 , Issue.5 , pp. 556-564
    • Martini, L.1    Whistler, J.L.2
  • 8
    • 33748571086 scopus 로고    scopus 로고
    • Phosphorylation: A molecular switch in opioid tolerance
    • Wang ZJ, Wang LX. Phosphorylation: a molecular switch in opioid tolerance. Life Sci 2006; 79(18): 1681-1691.
    • (2006) Life Sci , vol.79 , Issue.18 , pp. 1681-1691
    • Wang, Z.J.1    Wang, L.X.2
  • 9
    • 0025347712 scopus 로고
    • Phosphorylated mu-opioid receptor purified from rat brains lacks functional coupling with Gi1, a GTP-binding protein in reconstituted lipid vesicles
    • Harada H, Ueda H, Katada T, et al. Phosphorylated mu-opioid receptor purified from rat brains lacks functional coupling with Gi1, a GTP-binding protein in reconstituted lipid vesicles. Neurosci Lett 1990; 113(1): 47-49.
    • (1990) Neurosci Lett , vol.113 , Issue.1 , pp. 47-49
    • Harada, H.1    Ueda, H.2    Katada, T.3
  • 10
    • 0024560374 scopus 로고
    • Phosphorylation of mu-opioid receptors-a putative mechanism of selective uncoupling of receptor-Gi interaction, measured with low-Km GTPase and nucleotide-sensitive agonist binding
    • Harada H, Ueda H, Wada Y, et al. Phosphorylation of mu-opioid receptors-a putative mechanism of selective uncoupling of receptor-Gi interaction, measured with low-Km GTPase and nucleotide-sensitive agonist binding. Neurosci Lett 1989; 100(1-3): 221-226.
    • (1989) Neurosci Lett , vol.100 , Issue.1-3 , pp. 221-226
    • Harada, H.1    Ueda, H.2    Wada, Y.3
  • 11
    • 0023762715 scopus 로고
    • Reconstitution of rat brain mu opioid receptors with purified guanine nucleotide-binding regulatory proteins, Gi and Go
    • Ueda H, Harada H, Nozaki M, et al. Reconstitution of rat brain mu opioid receptors with purified guanine nucleotide-binding regulatory proteins, Gi and Go. Proc Natl Acad Sci USA 1988; 85(18): 7013-7017.
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.18 , pp. 7013-7017
    • Ueda, H.1    Harada, H.2    Nozaki, M.3
  • 12
    • 0031886497 scopus 로고    scopus 로고
    • Role of carboxyl terminus of mu-and delta-opioid receptor in agonist-induced down-regulation
    • Afify EA, Law PY, Riedl M, et al. Role of carboxyl terminus of mu-and delta-opioid receptor in agonist-induced down-regulation. Brain Res Mol Brain Res 1998; 54(1): 24-34.
    • (1998) Brain Res Mol Brain Res , vol.54 , Issue.1 , pp. 24-34
    • Afify, E.A.1    Law, P.Y.2    Riedl, M.3
  • 13
    • 0030875721 scopus 로고    scopus 로고
    • Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail
    • Pak Y, O’Dowd BF, George SR. Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail. J Biol Chem 1997; 272(40): 24961-24965.
    • (1997) J Biol Chem , vol.272 , Issue.40 , pp. 24961-24965
    • Pak, Y.1    O’Dowd, B.F.2    George, S.R.3
  • 14
    • 0035823506 scopus 로고    scopus 로고
    • mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation
    • Belcheva MM, Szucs M, Wang D, et al. mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation. J Biol Chem 2001; 276(36): 33847-33853.
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 33847-33853
    • Belcheva, M.M.1    Szucs, M.2    Wang, D.3
  • 15
    • 0027096482 scopus 로고
    • Protein kinase C activation increases the rate and magnitude of agonist-induced delta-opioid receptor down-regulation in NG108-15 cells
    • Gucker S, Bidlack JM. Protein kinase C activation increases the rate and magnitude of agonist-induced delta-opioid receptor down-regulation in NG108-15 cells. Mol Pharmacol 1992; 42(4): 656-665.
    • (1992) Mol Pharmacol , vol.42 , Issue.4 , pp. 656-665
    • Gucker, S.1    Bidlack, J.M.2
  • 16
    • 0030922877 scopus 로고    scopus 로고
    • Site mutation in the rat mu-opioid receptor demonstrates the involvement of calcium/calmodulin-dependent protein kinase II in agonist-mediated desensitization
    • Koch T, Kroslak T, Mayer P, et al. Site mutation in the rat mu-opioid receptor demonstrates the involvement of calcium/calmodulin-dependent protein kinase II in agonist-mediated desensitization. J Neurochem 1997; 69(4): 1767-1770.
    • (1997) J Neurochem , vol.69 , Issue.4 , pp. 1767-1770
    • Koch, T.1    Kroslak, T.2    Mayer, P.3
  • 17
    • 0029085874 scopus 로고
    • Agonist-dependent phosphorylation of the mouse delta-opioid receptor: Involvement of G protein-coupled receptor kinases but not protein kinase C
    • Pei G, Kieffer BL, Lefkowitz RJ, et al. Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C. Mol Pharmacol 1995; 48(2): 173-177.
    • (1995) Mol Pharmacol , vol.48 , Issue.2 , pp. 173-177
    • Pei, G.1    Kieffer, B.L.2    Lefkowitz, R.J.3
  • 18
    • 0032524665 scopus 로고    scopus 로고
    • A mitogen-activated protein kinase pathway is required for m-opioid receptor desensitization
    • Polakiewicz RD, Schieferl SM, Dorner LF, et al. A mitogen-activated protein kinase pathway is required for m-opioid receptor desensitization. J Biol Chem 1998; 273(20): 12402-12406.
    • (1998) J Biol Chem , vol.273 , Issue.20 , pp. 12402-12406
    • Polakiewicz, R.D.1    Schieferl, S.M.2    Dorner, L.F.3
  • 19
    • 0028832526 scopus 로고
    • Protein kinase C involvement in homologous desensitization of delta-opioid receptor coupled to Gi1-phospholipase C activation in Xenopus oocytes
    • Ueda H, Miyamae T, Hayashi C, et al. Protein kinase C involvement in homologous desensitization of delta-opioid receptor coupled to Gi1-phospholipase C activation in Xenopus oocytes. J Neurosci 1995; 15(11): 7485-7499.
    • (1995) J Neurosci , vol.15 , Issue.11 , pp. 7485-7499
    • Ueda, H.1    Miyamae, T.2    Hayashi, C.3
  • 20
    • 69149096686 scopus 로고    scopus 로고
    • Mechanisms underlying morphine analgesic tolerance and dependence-involvements of protein kinase C and anti-opioid glutamate-NMDA receptor system
    • Ueda H, Ueda M. Mechanisms underlying morphine analgesic tolerance and dependence-involvements of protein kinase C and anti-opioid glutamate-NMDA receptor system. Frontiers in Bioscience-regulation and function of opioid receptor genes. 2009; 14: 5260-5272.
    • (2009) Frontiers in Bioscience-regulation and function of opioid receptor genes , vol.14 , pp. 5260-5272
    • Ueda, H.1    Ueda, M.2
  • 21
    • 0032499738 scopus 로고    scopus 로고
    • Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness
    • Zhang J, Ferguson SS, Barak LS, et al. Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness. Proc Natl Acad Sci USA 1998; 95(12): 7157-7162.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.12 , pp. 7157-7162
    • Zhang, J.1    Ferguson, S.S.2    Barak, L.S.3
  • 22
    • 0024325328 scopus 로고
    • Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model
    • Ling GS, Paul D, Simantov R, et al. Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion model. Life Sci 1989; 45(18): 1627-1636.
    • (1989) Life Sci , vol.45 , Issue.18 , pp. 1627-1636
    • Ling, G.S.1    Paul, D.2    Simantov, R.3
  • 23
    • 0037329948 scopus 로고    scopus 로고
    • The importance of opioid tolerance: A therapeutic paradox
    • Thompson AR, Ray JB. The importance of opioid tolerance: a therapeutic paradox. J Am Coll Surg 2003; 196(2): 321-324.
    • (2003) J Am Coll Surg , vol.196 , Issue.2 , pp. 321-324
    • Thompson, A.R.1    Ray, J.B.2
  • 24
    • 0031727649 scopus 로고    scopus 로고
    • Gut motility and transit changes in patients receiving long-term methadone maintenance
    • Yuan CS, Foss JF, O’Connor M, et al. Gut motility and transit changes in patients receiving long-term methadone maintenance. J Clin Pharmacol 1998; 38(10): 931-935.
    • (1998) J Clin Pharmacol , vol.38 , Issue.10 , pp. 931-935
    • Yuan, C.S.1    Foss, J.F.2    O’Connor, M.3
  • 26
    • 0025971938 scopus 로고
    • Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801
    • Trujillo KA, Akil H. Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. Science 1991; 251(4989): 85-87.
    • (1991) Science , vol.251 , Issue.4989 , pp. 85-87
    • Trujillo, K.A.1    Akil, H.2
  • 27
    • 0033532037 scopus 로고    scopus 로고
    • Peripheral morphine analgesia resistant to tolerance in chronic morphine-treated mice
    • Ueda H, Inoue M. Peripheral morphine analgesia resistant to tolerance in chronic morphine-treated mice. Neurosci Lett 1999; 266(2): 105-108.
    • (1999) Neurosci Lett , vol.266 , Issue.2 , pp. 105-108
    • Ueda, H.1    Inoue, M.2
  • 28
    • 0035341402 scopus 로고    scopus 로고
    • Protein kinase C-mediated inhibition of mu-opioid receptor internalization and its involvement in the development of acute tolerance to peripheral mu-agonist analgesia
    • Ueda H, Inoue M, Matsumoto T. Protein kinase C-mediated inhibition of mu-opioid receptor internalization and its involvement in the development of acute tolerance to peripheral mu-agonist analgesia. J Neurosci 2001; 21(9): 2967-2973.
    • (2001) J Neurosci , vol.21 , Issue.9 , pp. 2967-2973
    • Ueda, H.1    Inoue, M.2    Matsumoto, T.3
  • 29
    • 0027985668 scopus 로고
    • Morphine analgesia in the formalin test: Evidence for forebrain and midbrain sites of action
    • Manning BH, Morgan MJ, Franklin KB. Morphine analgesia in the formalin test: evidence for forebrain and midbrain sites of action. Neuroscience 1994; 63(1): 289-294.
    • (1994) Neuroscience , vol.63 , Issue.1 , pp. 289-294
    • Manning, B.H.1    Morgan, M.J.2    Franklin, K.B.3
  • 30
    • 0037107189 scopus 로고    scopus 로고
    • Chronic morphine induces downregulation of spinal glutamate transporters: Implications in morphine tolerance and abnormal pain sensitivity
    • Mao J, Sung B, Ji RR, et al. Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity. J Neurosci 2002; 22(18): 8312-8323.
    • (2002) J Neurosci , vol.22 , Issue.18 , pp. 8312-8323
    • Mao, J.1    Sung, B.2    Ji, R.R.3
  • 31
    • 0033847254 scopus 로고    scopus 로고
    • Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies
    • Trujillo KA. Are NMDA receptors involved in opiate-induced neural and behavioral plasticity? A review of preclinical studies. Psychopharmacology (Berlin) 2000; 151 (2-3): 121-141.
    • (2000) Psychopharmacology (Berlin) , vol.151 , Issue.2-3 , pp. 121-141
    • Trujillo, K.A.1
  • 32
    • 0025959350 scopus 로고
    • The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality
    • Trujillo KA, Akil H. The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality. Pharmacol Biochem Behav 1991; 38(3): 673-675.
    • (1991) Pharmacol Biochem Behav , vol.38 , Issue.3 , pp. 673-675
    • Trujillo, K.A.1    Akil, H.2
  • 33
    • 0031021794 scopus 로고    scopus 로고
    • Enhancement of morphine actions in morphine-naive and morphinetolerant mice by LY 235959, a competitive antagonist of the NMDA receptor
    • Bhargava HN. Enhancement of morphine actions in morphine-naive and morphinetolerant mice by LY 235959, a competitive antagonist of the NMDA receptor. Gen Pharmacol 1997; 28(1): 61-64.
    • (1997) Gen Pharmacol , vol.28 , Issue.1 , pp. 61-64
    • Bhargava, H.N.1
  • 34
    • 33847047813 scopus 로고    scopus 로고
    • The drugs don’t work-or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-Acontaining AMPA receptors to hippocampal-dependent memory
    • Bannerman DM, Rawlins JN, Good MA. The drugs don’t work-or do they? Pharmacological and transgenic studies of the contribution of NMDA and GluR-Acontaining AMPA receptors to hippocampal-dependent memory. Psychopharmacology (Berlin) 2006; 188(4): 552-566.
    • (2006) Psychopharmacology (Berlin) , vol.188 , Issue.4 , pp. 552-566
    • Bannerman, D.M.1    Rawlins, J.N.2    Good, M.A.3
  • 35
    • 0042844731 scopus 로고    scopus 로고
    • Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence
    • Inoue M, Mishina M, Ueda H. Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. J Neurosci 2003; 23(16): 6529-6536.
    • (2003) J Neurosci , vol.23 , Issue.16 , pp. 6529-6536
    • Inoue, M.1    Mishina, M.2    Ueda, H.3
  • 36
    • 50149086108 scopus 로고    scopus 로고
    • Diversity of degradation signals in the ubiquitin-proteasome system
    • Ravid T, Hochstrasser M. Diversity of degradation signals in the ubiquitin-proteasome system. Nat Rev Mol Cell Biol 2008; 9(9): 679-690.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.9 , pp. 679-690
    • Ravid, T.1    Hochstrasser, M.2
  • 37
    • 69849086417 scopus 로고    scopus 로고
    • Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance
    • Ko SW, Wu LJ, Shum F, et al. Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance. Mol Brain 2008; 1(1): 2.
    • (2008) Mol Brain , vol.1 , Issue.1 , pp. 2
    • Ko, S.W.1    Wu, L.J.2    Shum, F.3
  • 38
    • 0036391985 scopus 로고    scopus 로고
    • The effects of NMDA receptor antagonists on acute morphine antinociception in mice
    • Kozela E, Popik P. The effects of NMDA receptor antagonists on acute morphine antinociception in mice. Amino Acids 2002; 23(1-3): 163-168.
    • (2002) Amino Acids , vol.23 , Issue.1-3 , pp. 163-168
    • Kozela, E.1    Popik, P.2
  • 39
    • 0037278221 scopus 로고    scopus 로고
    • Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice
    • Kozela E, Pilc A, Popik P. Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice. Psychopharmacology (Berlin) 2003; 165(3): 245-251.
    • (2003) Psychopharmacology (Berlin) , vol.165 , Issue.3 , pp. 245-251
    • Kozela, E.1    Pilc, A.2    Popik, P.3
  • 40
    • 0344255683 scopus 로고    scopus 로고
    • Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats
    • Liaw WJ, Zhang B, Tao F, et al. Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats. Neuroscience 2004; 123(1): 11-15.
    • (2004) Neuroscience , vol.123 , Issue.1 , pp. 11-15
    • Liaw, W.J.1    Zhang, B.2    Tao, F.3
  • 41
    • 0037430852 scopus 로고    scopus 로고
    • Microarray analysis of genes expressed in the frontal cortex of rats chronically treated with morphine and after naloxone precipitated withdrawal
    • Ammon S, Mayer P, Riechert U, et al. Microarray analysis of genes expressed in the frontal cortex of rats chronically treated with morphine and after naloxone precipitated withdrawal. Brain Res Mol Brain Res 2003; 112(1-2): 113-125.
    • (2003) Brain Res Mol Brain Res , vol.112 , Issue.1-2 , pp. 113-125
    • Ammon, S.1    Mayer, P.2    Riechert, U.3
  • 42
    • 10044233862 scopus 로고    scopus 로고
    • 2þ-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons
    • 2þ-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. J Neurosci 2004; 24(48): 10846-10857.
    • (2004) J Neurosci , vol.24 , Issue.48 , pp. 10846-10857
    • Yang, L.1    Mao, L.2    Tang, Q.3
  • 43
    • 45149087954 scopus 로고    scopus 로고
    • Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala
    • Befort K, Filliol D, Ghate A, et al. Mu-opioid receptor activation induces transcriptional plasticity in the central extended amygdala. Eur J Neurosci 2008; 27(11): 2973-2984.
    • (2008) Eur J Neurosci , vol.27 , Issue.11 , pp. 2973-2984
    • Befort, K.1    Filliol, D.2    Ghate, A.3
  • 44
    • 0038389083 scopus 로고    scopus 로고
    • Downregulation of neuronal cdk5/p35 in opioid addicts and opiate-treated rats: Relation to neurofilament phosphorylation
    • Ferrer-Alcon M, La Harpe R, Guimon J, et al. Downregulation of neuronal cdk5/p35 in opioid addicts and opiate-treated rats: relation to neurofilament phosphorylation. Neuropsychopharmacology 2003; 28(5): 947-955.
    • (2003) Neuropsychopharmacology , vol.28 , Issue.5 , pp. 947-955
    • Ferrer-Alcon, M.1    La Harpe, R.2    Guimon, J.3
  • 45
    • 0035940422 scopus 로고    scopus 로고
    • Regulation of NMDA receptors by cyclin-dependent kinase-5
    • Li BS, Sun MK, Zhang L, et al. Regulation of NMDA receptors by cyclin-dependent kinase-5. Proc Natl Acad Sci U S A 2001; 98(22), 12742-12747.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.22 , pp. 12742-12747
    • Li, B.S.1    Sun, M.K.2    Zhang, L.3
  • 46
    • 38349009068 scopus 로고    scopus 로고
    • Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors
    • Zhang S, Edelmann L, Liu J, et al. Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors. J Neurosci 2008; 28(2): 415-424.
    • (2008) J Neurosci , vol.28 , Issue.2 , pp. 415-424
    • Zhang, S.1    Edelmann, L.2    Liu, J.3
  • 47
    • 0032555431 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor induction of N-methyl-D-aspartate receptor subunit NR2A expression in cultured rat cortical neurons
    • Small DL, Murray CL, Mealing GA, et al. Brain derived neurotrophic factor induction of N-methyl-D-aspartate receptor subunit NR2A expression in cultured rat cortical neurons. Neurosci Lett 1998; 252(3): 211-214.
    • (1998) Neurosci Lett , vol.252 , Issue.3 , pp. 211-214
    • Small, D.L.1    Murray, C.L.2    Mealing, G.A.3
  • 48
    • 12144283981 scopus 로고    scopus 로고
    • Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia
    • Takayama N, Ueda H. Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia. J Neurosci 2005; 25(2): 430-435.
    • (2005) J Neurosci , vol.25 , Issue.2 , pp. 430-435
    • Takayama, N.1    Ueda, H.2
  • 49
    • 70350069206 scopus 로고    scopus 로고
    • Microglia activation is involved in the initiation of morphine analgesic tolerance
    • Charleston, SC
    • Yonekubo S, Matsushita Y, Ueda H. Microglia activation is involved in the initiation of morphine analgesic tolerance. INRC, Charleston, SC, 2008: 46.
    • (2008) INRC , pp. 46
    • Yonekubo, S.1    Matsushita, Y.2    Ueda, H.3
  • 50
    • 58149214046 scopus 로고    scopus 로고
    • Curcumin blocks chronic morphine analgesic tolerance and brain-derived neurotrophic factor upregulation
    • Matsushita Y, Ueda H. Curcumin blocks chronic morphine analgesic tolerance and brain-derived neurotrophic factor upregulation. Neuroreport 2009; 20(1): 63-68.
    • (2009) Neuroreport , vol.20 , Issue.1 , pp. 63-68
    • Matsushita, Y.1    Ueda, H.2
  • 51
    • 0037095689 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons
    • Akbarian S, Rios M, Liu RJ, et al. Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. J Neurosci 2002; 22(10): 4153-4162.
    • (2002) J Neurosci , vol.22 , Issue.10 , pp. 4153-4162
    • Akbarian, S.1    Rios, M.2    Liu, R.J.3
  • 52
    • 34547102250 scopus 로고    scopus 로고
    • Expression of the rat sterol regulatory elementbinding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1)
    • Deng X, Yellaturu C, Cagen L, et al. Expression of the rat sterol regulatory elementbinding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1). J Biol Chem 2007; 282(24): 17517-17529.
    • (2007) J Biol Chem , vol.282 , Issue.24 , pp. 17517-17529
    • Deng, X.1    Yellaturu, C.2    Cagen, L.3
  • 53
    • 49549105302 scopus 로고    scopus 로고
    • A critical role of Sp1 transcription factor in regulating gene expression in response to insulin and other hormones
    • Solomon SS, Majumdar G, Martinez-Hernandez A, et al. A critical role of Sp1 transcription factor in regulating gene expression in response to insulin and other hormones. Life Sci 2008; 83(9-10): 305-312.
    • (2008) Life Sci , vol.83 , Issue.9-10 , pp. 305-312
    • Solomon, S.S.1    Majumdar, G.2    Martinez-Hernandez, A.3
  • 54
    • 0035968063 scopus 로고    scopus 로고
    • Changes in the expression of glial glutamate transporters in the rat brain accompanied with morphine dependence and naloxoneprecipitated withdrawal
    • Ozawa T, Nakagawa T, Shige K, et al. Changes in the expression of glial glutamate transporters in the rat brain accompanied with morphine dependence and naloxoneprecipitated withdrawal. Brain Res 2001; 905(1-2): 254-258.
    • (2001) Brain Res , vol.905 , Issue.1-2 , pp. 254-258
    • Ozawa, T.1    Nakagawa, T.2    Shige, K.3
  • 55
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson JW, Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 1987; 325(6104): 529-531.
    • (1987) Nature , vol.325 , Issue.6104 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 56
    • 47749102938 scopus 로고    scopus 로고
    • Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase
    • Yoshikawa M, Shinomiya T, Takayasu N, et al. Long-term treatment with morphine increases the D-serine content in the rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase. J Pharmacol Sci 2008; 107(3): 270-276.
    • (2008) J Pharmacol Sci , vol.107 , Issue.3 , pp. 270-276
    • Yoshikawa, M.1    Shinomiya, T.2    Takayasu, N.3
  • 57
    • 0035111016 scopus 로고    scopus 로고
    • The involvement of glial cells in the development of morphine tolerance
    • Song P, Zhao ZQ. The involvement of glial cells in the development of morphine tolerance. Neurosci Res 2001; 39(3): 281-286.
    • (2001) Neurosci Res , vol.39 , Issue.3 , pp. 281-286
    • Song, P.1    Zhao, Z.Q.2
  • 58
    • 33750975922 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia
    • Liu W, Wang C-H, Cui, Y, et al. Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia. Neurosci Lett 2006; 410(3): 174-177.
    • (2006) Neurosci Lett , vol.410 , Issue.3 , pp. 174-177
    • Liu, W.1    Wang, C.-H.2    Cui, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.