LACTATION BIOLOGY SYMPOSIUM: Role of colostrum and colostrum components on glucose metabolism in neonatal calves

Journal of Animal Science

Volumn 91, Issue 2, 2013, Pages 685-695

  Hammon, H M ^a   Steinhoff Wagner, J ^a   Flor, J ^a   Schonhusen U ^a   Metges, C C ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

Colostrum feeding; Endogenous glucose production; Glucose absorption; Neonatal calf

Indexed keywords

GLUCOSE;

ANIMAL; ARTICLE; BLOOD; CATTLE; CHEMISTRY; COLOSTRUM; GLUCOSE BLOOD LEVEL; METABOLISM; NEWBORN; PHYSIOLOGY;

ANIMALS; ANIMALS, NEWBORN; BLOOD GLUCOSE; CATTLE; COLOSTRUM; GLUCOSE;

EID: 84882581582     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2012-5758     Document Type: Article

References (141)

1. Alexander, A. N., and H. V. Carey. 1999. Oral IGF-I enhances nutrient and electrolyte absorption in neonatal piglet intestine. Am. J. Physiol. 277:G619-G625.
2. Arsenault, P., and D. Menard. 1987. Stimulatory effects of epidermal growth factor on deoxyribonucleic acid synthesis in the gastrointestinal tract of the suckling mouse. Comp. Biochem. Physiol. B. 86:123-127.
3. Attig, L., T. Larcher, A. Gertler, L. Abdennebi-Najar, and J. Djiane. 2011. Postnatal leptin is necessary for maturation of numerous organs in newborn rats. Organogenesis 7:88-94.
4. Aynsley-Green, A. 1988. Metabolic and endocrine interrelationships in the human fetus and neonate: An overview of the control of the adaptation to postnatal nutrition. In: B. S. Lindblad, editor, Perinatal nutrition. Academic Press, New York, NY. p. 161-191.
5. Bach, A. 2012. Nourishing and managing the dam and postnatal calf for optimal lactation, reproduction, and immunity. J. Anim. Sci. 90:1835-1845.
6. Ballard, F. J., and I. T. Oliver. 1965. Carbohydrate metabolism in liver from foetal and neonatal sheep. Biochem. J. 95:191-200.
7. Barrington, G. M., T. B. McFadden, M. T. Huyler, and T. E. Besser. 2001. Regulation of colostrogenesis in cattle. Livest. Prod. Sci. 70:95-104.
8. Bartol, F. F., and C. A. Bagnell. 2012. Lactocrine programming of the female reproductive tract development: Environmental connections to the reproductive continuum. Mol. Cell Endocrinol. 354:16-21.
9. Battaglia, F. C., and G. Meschia. 1978. Principal substrates of fetal metabolism. Physiol. Rev. 58:499-527.
10. Baumrucker, C. R., M. H. Green, and J. W. Blum. 1994a. Effects of dietary rhIGF-I in neonatal calves on the appearance of glucose, insulin, D-xylose, globulins and γ-glutamyltransferase in blood. Domest. Anim. Endocrinol. 11:393-403.
11. Baumrucker, C. R., D. L. Hadsell, and J. W. Blum. 1994b. Effects of dietary insulin-like growth factor I on growth and insulin-like growth factor receptors in neonatal calf intestine. J. Anim. Sci. 72:428-433.
12. Bell, A. W., and D. E. Bauman. 1997. Adaptations of glucose metabolism during pregnancy and lactation. J. Mammary Gland Biol. Neoplasia 2:265-278.
13. Bell, A. W., and R. A. Ehrhardt. 2002. Regulation of placental nutrient transport and implications for fetal growth. Nutr. Res. Rev. 15:211-230.
14. Bell, A. W., C. L. Ferrell, and H. C. Freetly. 2005a. Pregnancy and fetal metabolism. In: J. Dijkstra, J. M. Forbes, and J. France, editors, Quantitative aspects of ruminant digestion and metabolism. CAB, Wallingford, UK. p. 523-550.
15. Bell, A. W., P. L. Greenwood, and R. A. Ehrhardt. 2005b. Regulation of metabolism and growth during prenatal life. In: D. G. Burrin and J. H. Mersmann, editors, Biology of metabolism in growing animals. Elsevier, London, UK. p. 3-34.
16. Berseth, C. L. 1987. Enhancement of intestinal growth in neonatal rats by epidermal growth factor in milk. Am. J. Physiol. 253:G662-G665.
17. Bird, A. R., W. J. Croom Jr., Y. F. Fan, B. L. Black, B. W. McBride, and I. L. Taylor. 1996. Peptide regulation of intestinal glucose absorption. J. Anim. Sci. 74:2523-2540.
18. Bittrich, S., C. Morel, C. Philipona, Y. Zbinden, H. M. Hammon, and J. W. Blum. 2002. Physiological traits in preterm calves during their first week of life. J. Anim. Physiol. Anim. Nutr. 86:185-198.
19. Bittrich, S., C. Philipona, H. M. Hammon, V. Romé, P. Guilloteau, and J. W. Blum. 2004. Preterm as compared with fullterm neonatal calves are characterized by morphological and functional immaturity of the small intestine. J. Dairy Sci. 87:1786-1795.
20. Blättler, U., H. M. Hammon, C. Morel, C. Philipona, A. Rauprich, V. Rome, I. Le Huerou-Luron, P. Guilloteau, and J. W. Blum. 2001. Feeding colostrum, its composition and feeding duration variably modify proliferation and morphology of the intestine and digestive enzyme activities of neonatal calves. J. Nutr. 131:1256-1263.
21. Blum, J. W. 2006. Nutritional physiology of neonatal calves. J. Anim. Physiol. Anim. Nutr. 90:1-11.
22. Blum, J. W., and C. R. Baumrucker. 2008. Insulin-like growth factors (IGFs), IGF binding proteins, and other endocrine factors in milk: Role in the newborn. In: Z. Bösze, editor, Bioactive components of milk. Springer, New York, NY. p. 397-422.
23. Blum, J. W., and H. Hammon. 1999. Endocrine and metabolic aspects in milk-fed calves. Domest. Anim. Endocrinol. 17:219-230.
24. Blum, J. W., and H. Hammon. 2000. Colostrum effects on the gastrointestinal tract, and on nutritional, endocrine and metabolic parameters in neonatal calves. Livest. Prod. Sci. 66:151-159.
25. Blum, J. W., Y. Zbinden, H. M. Hammon, and Y. Chilliard. 2005. Plasma leptin status in young calves: Effects of preterm birth, age, glucocorticoid status, suckling, and feeding with an automatic feeder or by bucket. Domest. Anim. Endocrinol. 28:119-133.
26. Böhme, H. J., G. Sparmann, and E. Hofmann. 1983. Biochemistry of liver development in the perinatal period. Experientia 39:473-483.
27. Boudry, C., J.-P. Dehoux, D. Portetelle, and A. Buldgen. 2008. Bovine colostrum as a natural growth promoter for newly weaned piglets: A review. BASE 12:157-170.
28. Brameld, J. M., R. S. Gilmour, and P. J. Buttery. 1999. Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes. J. Nutr. 129:1298-1306.
29. Brockman, R. P., and B. Laarveld. 1986. Hormonal regulation of metabolism in ruminants: A review. Livest. Prod. Sci. 14:313-334.
30. Bühler, C., H. Hammon, G. L. Rossi, and J. W. Blum. 1998. Small intestinal morphology in eight-day-old calves fed colostrum for different durations or only milk replacer and treated with long-R-3-insulin-like growth factor I and growth hormone. J. Anim. Sci. 76:758-765.
31. Burrin, D. G., T. A. Davis, S. Ebner, P. A. Schoknecht, M. L. Fiorotto, P. J. Reeds, and S. McAvoy. 1995. Nutrient-independent and nutrient-dependent factors stimulate protein synthesis in colostrum-fed newborn pigs. Pediatr. Res. 37:593-599.
32. Burrin, D. G., T. J. Wester, T. A. Davis, S. Amick, and J. P. Heath. 1996. Orally administered IGF-I increases intestinal mucosal growth in formula-fed neonatal pigs. Am. J. Physiol. 39:R1085-R1091.
33. Butler, S. T., A. L. Marr, S. H. Pelton, R. P. Radcliff, M. C. Lucy, and W. R. Butler. 2003. Insulin restores GH responsiveness during lactation-induced negative energy balance in dairy cattle: Effects on expression of IGF-I and GH receptor 1A. J. Endocrinol. 176:205-217.
34. Campana, W. M., and C. R. Baumrucker. 1995. Hormones and growth factors in bovine milk. In: R. G. Jensen, editor, Handbook of milk composition. Academic Press, New York, NY. p. 476-494.
35. Carron, J., C. Morel, J. W. Blum, and H. M. Hammon. 2005a. Effects of dexamethasone and colostrum feeding on mRNA levels and binding capacities of β-adrenergic receptors in the liver of neonatal calves. Domest. Anim. Endocrinol. 28:257-271.
36. Carron, J., C. Morel, H. M. Hammon, and J. W. Blum. 2005b. Ontogenetic development of mRNA levels and binding sites of hepatic β-adrenergic receptors in cattle. Domest. Anim. Endocrinol. 28:320-330.
37. Casabiell, X., V. Piñeiro, M. A. Tomé, R. Peinó, C. Diéguez, and F. F. Casanueva. 1997. Presence of leptin in colostrum and/or breast milk from lactating mothers: A potential role in the regulation of neonatal food intake. J. Clin. Endocrinol. Metab. 82:4270-4273.
38. Chilliard, Y., M. Bonnet, C. Delavaud, Y. Faulconnier, C. Leroux, J. Djiane, and F. Bocquier. 2001. Leptin in ruminants. Gene expression in adipose tissue and mammary gland, and regulation of plasma concentration. Domest. Anim. Endocrinol. 21:271-295.
39. Cordano, P., H. M. Hammon, C. Morel, A. Zurbriggen, and J. W. Blum. 2000. Messenger RNA of insulin-like growth factor (IGF) quan-tification and presence of IGF binding proteins, and receptors for growth hormone, IGF-I and insulin, determined by reverse-transcribed polymerase chain reaction, in the liver of growing and mature male cattle. Domest. Anim. Endocrinol. 19:191-208.
40. Dawkins, M. J. 1961. Changes in glucose-6-phosphatase activity in liver and kidney at birth. Nature 191:72-73.
41. Donkin, S. S. 1999. Role of the endocrine pancreas in animal metabolism, growth and performance. In: S. G. Pierynowski and R. Zabielski, editors, Biology of the pancreas in growing animals. Elsevier, Amsterdam, The Netherlands. p. 315-328.
42. Donkin, S. S., and L. E. Armentano. 1994. Regulation of gluco-neogenesis by insulin and glucagon in neonatal bovine. Am. J. Physiol. 266:R1229-R1237.
43. Donkin, S. S., and H. Hammon. 2005. Hepatic gluconeogenesis in developing ruminants. In: D. G. Burrin and H. J. Mersmann, editors, Biology of growing animals. Elsevier, Edinburgh, Great Britain. p. 375-390.
44. Donovan, S. M., J. C. J. Chao, R. T. Zijlstra, and J. Odle. 1997. Orally administered iodinated recombinant human insulin-like growth factor-I (125I-rhIGF-I) is poorly absorbed by the newborn piglet. J. Pediatr. Gastroenterol. Nutr. 24:174-182.
45. Douglas, R. G., P. D. Gluckman, K. Ball, B. Breier, and J. H. F. Shaw. 1991. The effects of infusion of insulinlike growth factor (IGF) 1, IGF-ll, and insulin on glucose and protein metabolism in fasted lambs. J. Clin. Invest. 88:614-622.
46. Forhead, A. J., S. Cutts, P. A. Matthews, and A. L. Fowden. 2009. Role of thyroid hormones in the developmental control of tissue glycogen in fetal sheep near term. Exp. Physiol. 94:1079-1087.
47. Fowden, A. L. 1997. Comparative aspects of fetal carbohydrate metabolism. Equine Vet. J. Suppl. 24:19-25.
48. Fowden, A. L., and A. J. Forhead. 2011. Adrenal glands are essential for activation of glucogenesis during undernutrition in fetal sheep near term. Am. J. Physiol. 300:E94-E102.
49. Fowden, A. L., J. Li, and A. J. Forhead. 1998. Glucocorticoids and the preparation for life after birth: Are there long-term consequences of the life insurance? Proc. Nutr. Soc. 57:113-122.
50. Fowden, A. L., J. Mapstone, and A. J. Forhead. 2001. Regulation of glucogenesis by thyroid hormones in fetal sheep during late gestation. J. Endocrinol. 170:461-469.
51. Fowden, A. L., A. N. Sferruzzi-Perri, P. M. Coan, M. Constancia, and G. J. Burton. 2009. Placental efficiency and adaptation: Endocrine regulation. J. Physiol. 587:3459-3472.
52. Gauthier, S. F., Y. Pouliot, and J. L. Maubois. 2006. Growth factors from bovine milk and colostrum: Composition, extraction and biological activities. Lait 86:99-125.
53. Georgiev, I. P., T. M. Georgieva, M. Pfaffl, H. M. Hammon, and J. W. Blum. 2003. Insulin-like growth factor and insulin receptors in intestinal mucosa of neonatal calves. J. Endocrinol. 176:121-132.
54. Georgieva, T. M., I. P. Georgiev, E. Ontsouka, H. M. Hammon, M. Pfaffl, and J. W. Blum. 2003. Abundance of message for insulin-like growth factors-I and -II and for receptors for growth hormone, insulin-like growth factors-I and -II and insulin in the intestine and liver of pre- and full-term calves. J. Anim. Sci. 81:2294-2300.
55. Girard, J. 1990. Metabolic adaptations to changes of nutrition at birth. Biol. Neonate 58:3-15.
56. Girard, J., P. Ferré, J. P. Pégorier, and P. H. Duée. 1992. Adaptions of glucose and fatty acid metabolism during perinatal period and suckling-weaning transition. Physiol. Rev. 72:507-562.
57. Gluckman, P. D., S. V. Sizonenko, and N. S. Bassett. 1999. The transition from fetus to neonate - An endocrine perspective. Acta Paediatr., Suppl. 88:7-11.
58. Godden, S. 2008. Colostrum management for dairy calves. Vet. Clin. N. Am. Food A. 24:19-39.
59. Grün, E. 1981. Ontogenetic development of enzymes of carbohydrate metabolism in liver of swine. Monatsh. Veterinaermed. 36:11-19.
60. Grütter, R., and J. W. Blum. 1991. Insulin and glucose in neonatal calves after peroral insulin and intravenous glucose administration. Reprod. Nutr. Dev. 31:389-397.
61. Guilloteau, P., I. Le Huërou-Luron, J. A. Chayvialle, R. Toullec, R. Zabielski, and J. W. Blum. 1997. Gut regulatory peptides in young cattle and sheep. J. Vet. Med. A44:1-23.
62. Guilloteau, P., R. Zabielski, and J. W. Blum. 2009. Gastrointestinal tract and digestion in the young ruminant: Ontogenesis, adaptations, consequences and manipulations. J. Physiol. Pharmakol. 60 (Suppl. 2):37-46.
63. Hadorn, U., H. Hammon, R. M. Bruckmaier, and J. W. Blum. 1997. Delaying colostrum intake by one day has important effects on metabolic traits and on gastrointestinal and metabolic hormones in neonatal calves. J. Nutr. 127:2011-2023.
64. Hammon, H., and J. W. Blum. 1997a. Prolonged colostrum feeding enhances xylose absorption in neonatal calves. J. Anim. Sci. 75:2915-2919.
65. Hammon, H., and J. W. Blum. 1997b. Thesomatotropic axis in neonatal calves can be modulated by nutrition, growth hormone and Long-R3-IGF-I. Am. J. Physiol. 273:E130-E138.
66. 3-insulin-like growth factor-I administration. Biol. Neonate 73:121-128.
67. Hammon, H. M., and J. W. Blum. 1998b. Metabolic and endocrine traits of neonatal calves are influenced by feeding colostrum for different durations or only milk replacer. J. Nutr. 128:624-632.
68. Hammon, H. M., and J. W. Blum. 1999. Free amino acids in plasma of neonatal calves are influenced by feeding colostrum for different durations or by feeding only milk replacer. J. Anim. Physiol. Anim. Nutr. 82:193-204.
69. Hammon, H. M., and J. W. Blum. 2002. Feeding different amounts of colostrum or only milk replacer modify receptors of intestinal insulin-like growth factors and insulin in neonatal calves. Domest. Anim. Endocrinol. 22:155-168.
70. Hammon, H. M., C. Philipona, Y. Zbinden, J. W. Blum, and S. S. Donkin. 2005. Effects of dexamethasone and growth hormone treatment on hepatic gluconeogenic enzymes in calves. J. Dairy Sci. 88:2107-2116.
71. Hammon, H. M, S. N. Sauter, M. Reist, Y. Zbinden, C. Philipona, C. Morel, and J. W. Blum. 2003. Dexamethasone and colostrum feeding affect hepatic gluconeogenic enzymes differently in neonatal calves. J. Anim. Sci. 81:3095-3106.
72. Hammon, H. M., J. Steinhoff-Wagner, U. Schönhusen, C. C. Metges, and J. W. Blum. 2012. Energy metabolism in the newborn farm animal with emphasis on the calf: Endocrine changes and responses to milk-born and systemic hormones. Domest. Anim. Endocrinol 43:171-185.
73. Hay Jr., W. W. 2006. Recent observations on the regulation of fetal metabolism by glucose. J. Physiol. 572:17-24.
74. Hostettler-Allen, R., L. Tappy, and J. W. Blum. 1994. Insulin resistance, hyperglycemia and glucosuria in intensively milk-fed calves. J. Anim. Sci. 72:160-173.
75. Hugi, D., L. Tappy, H. Sauerwein, R. M. Bruckmaier, and J. W. Blum. 1998. Insulin-dependent glucose utilization in intensively milk-fed veal calves is modulated by supplemental lactose in an age-dependent manner. J. Nutr. 128:1023-1030.
76. Hwang, K.-A., Y.-J. Hwang, W. Ha, Y.-K. Choo, and K. Ko. 2012. Oral administration of insulin-like growth factor-I from colos-tral whey reduces blood glucose in streptozotocin-induced diabetic mice. Br. J. Nutr. 108:39-45.
77. Jitrapakdee, S., and J. W. Wallace. 1999. Structure and regulation of pyruvate carboxylase. Biochem. J. 340:1-16.
78. Jones, J. I., and D. R. Clemmons. 1995. Insulin-like growth factors and their binding proteins: Biological action. Endocr. Rev. 16:3-34.
79. Kalhan, S., and P. Parimi. 2000. Gluconeogenesis in the fetus and neonate. Sem. Perinatol. 24:94-106.
80. Kelly, D. 1994. Colostrum, growth factors and intestinal development in pigs. In: W. B. Souffrant and H. Hagemeister, editors, Digestive physiology in pigs. European Federation of Animal Science (EAAP), Bad Doberan, Germany. p. 151-166.
81. Koldovský, O. 1989. Search for role of milk-borne biologically active peptides for the suckling. J. Nutr. 119:1543-1551.
82. Koldovský, O. 1994. Hormonally active peptides in human milk. Acta Paediatr., Suppl. 402:89-93.
83. Kraus-Friedmann, N. 1984. Hormonal regulation of hepatic gluco-neogenesis. Physiol. Rev. 64:170-259.
84. Krebs, H. A., and T. Yoshida. 1963. Renal gluconeogenesis: 2. The gluconeogenic capacity of the kidney cortex of various species. Biochem. J. 89:398-400.
85. Kühne, S., H. M. Hammon, R. M. Bruckmaier, C. Morel, Y. Zbinden, and J. W. Blum. 2000. Growth performance, metabolic and endocrine traits, and absorptive capacity in neonatal calves fed either colostrum or milk replacer at two levels. J. Anim. Sci. 78:609-620.
86. Kurz, M. M., and L. B. Willett. 1992. The clearance of carbon-14-fructose, carbon-14-glucose, carbon-14-sorbitol by calves at birth and 7 days of age. J. Dairy Sci. 75:236-246.
87. Lepine, A. J., R. D. Boyd, and D. M. Whitehead. 1991. Effect of colostrum intake on hepatic gluconeogenesis and fatty acid oxidation in the neonatal pig. J. Anim. Sci. 69:1966-1974.
88. Leury, B. J., K. D. Chandler, A. R. Bird, and A. W. Bell. 1990. Effects of maternal undernutrition and exercise on glucose kinetics in fetal sheep. Br. J. Nutr. 64:463-472.
89. Liggins, G. C. 1994. The role of cortisol in preparing the fetus for birth. Reprod. Fertil. Dev. 6:141-150.
90. McDowell, G. H. 1983. Hormonal control of glucose homoeostasis in ruminants. Proc. Nutr. Soc. 42:149-167.
91. McFadin, E. L., C. D. Morrison, P. R. Buff, N. C. Whitley, and D. H. Keisler. 2002. Leptin concentrations in periparturient ewes and their subsequent offspring. J. Anim. Sci. 80:738-743.
92. McGowan, J. E., P. W. Aldoretta, and W. W. Hay Jr. 1995. Contribution of fructose and lactate produced in the placenta to the calculation of fetal glucose oxidation rate. Am. J. Physiol. 269:E834-E839.
93. McMillen, I. C., B. S. Muhlhausler, J. A. Duffield, and B. S. J. Yuen. 2004. Prenatal programming of postnatal obesity: Fetal nutrition and the regulation of leptin synthesis and secretion before birth. Proc. Nutr. Soc. 63:405-412.
94. Mellor, D. J., and F. A. Cockburn. 1986. A comparison of energy metabolism in the new-born infant, piglet and lamb. Q. J. Exp. Physiol. 71:361-379.
95. Meznarich, H. K., W. W. Hay Jr., J. W. Sparks, G. Meschia, and F. C. Battaglia. 1987. Fructose disposal and oxidation rates in the ovine fetus. Q. J. Exp. Physiol. 72:617-625.
96. Montoni, A., S. F. Gauthier, C. Richard, P. E. Poubelle, Y. Chouinard, and Y. Pouliot. 2009. Bovine colostrum as substrate for the preparation of growth factor-enriched protein extracts: Identifying the optimal collection period during lactation. Dairy Sci. Technol. 89:511-518.
97. Morton, G. J., and M. W. Schwartz. 2011. Leptin and the central nervous system control of glucose metabolism. Physiol. Rev. 91:389-411.
98. Nussbaum, A., G. Schiessler, H. M. Hammon, and J. W. Blum. 2002. Growth performance and metabolic and endocrine traits in calves pair-fed by bucket or by automate starting in the neonatal period. J. Anim. Sci. 80:1545-1555.
99. Odle, J., R. T. Zijlstra, and S. M. Donovan. 1996. Intestinal effects of milkborne growth factors in neonates of agricultural importance. J. Anim. Sci. 74:2509-2522.
100. Ontsouka, E. C., H. M. Hammon, and J. W. Blum. 2004b. Expression of insulin-like growth factors (IGF)-1 and -2, IGF-binding pro-teins-2 and -3, and receptors for growth hormone, IGF type-1 and -2 and insulin in the gastrointestinal tract of neonatal calves. Growth Factors 22:63-69.
101. Ontsouka, E. C., B. Korczak, H. M. Hammon, and J. W. Blum. 2004c. Real-time PCR quantification of bovine lactase mRNA: Localization in the gastrointestinal tract of milk-fed calves. J. Dairy Sci. 87:4230-4237.
102. Ontsouka, E. C., C. Philipona, H. M. Hammon, and J. W. Blum. 2004d. Abundance of mRNA encoding for components of the somato-tropic axis and insulin receptor in different layers of the jejunum and ileum of neonatal calves. J. Anim. Sci. 82:3181-3188.
103. Ontsouka, E. C., S. N. Sauter, J. W. Blum, and H. M. Hammon. 2004a. Effects of colostrum feeding and dexamethasone treatment on mRNA levels of insulin-like growth factors (IGF)-I and-II, IGF binding proteins -2 and -3, and on receptors for growth hormone, IGF-I, IGF-II, and insulin in the gastrointestinal tract of neonatal calves. Domest. Anim. Endocrinol. 26:155-175.
104. Père, M. C. 1995. Maternal and fetal blood levels of glucose, lac-tate, fructose, and insulin in the conscious pig. J. Anim. Sci. 73:2994-2999.
105. Père, M. C. 2003. Materno-foetal exchanges and utilisation of nutrients by the foetus: Comparison between species. Reprod. Nutr. Dev. 43:1-15.
106. Philipps, A. F., P. J. Kling, J. G. Grille, and B. Dvorak. 2002. Intestinal transport of insulin-like growth factor-I (IGF-I) in the suckling rat. J. Pediatr. Gastroenterol. Nutr. 35:539-544.
107. Pilkis, S. J., and D. K. Granner. 1992. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu. Rev. Physiol. 54:885-909.
108. Prior, R. L., and R. A. Scott. 1977. Ontogeny of gluconeogenesis in the bovine fetus: Influence of maternal dietary energy. Dev. Biol. 58:384-393.
109. Purup, S., M. Vestergaard, L. O. Pedersen, and K. Sejrsen. 2007. Biological activity of bovine milk on proliferation of human intestinal cells. J. Dairy Res. 74:58-65.
110. Rauprich, A. B. E., H. M. Hammon, and J. W. Blum. 2000. Effects of feeding colostrum and a formula with nutrient contents as colostrum on metabolic and endocrine traits in neonatal calves. Biol. Neonate 78:53-64.
111. Richet, E., M. J. Davicco, and J. P. Barlet. 1985. Plasma catechol-amine concentrations in lambs and calves during the perinatal period. Reprod. Nutr. Dev. 25:1007-1016.
112. Rizza, R. A., P. E. Cryer, M. W. Haymond, and J. E. Gerich. 1980. Adrenergic mechanisms of catecholamine action on glucose ho-meostasis in man. Metabolism 29:1155-1163.
113. Roffler, B., A. Fäh, S. N. Sauter, H. M. Hammon, P. Gallmann, G. Brem, and J. W. Blum. 2003. Intestinal morphology, epithelial cell proliferation, and absorptive capacity in neonatal calves fed milk-born insulin-like growth factor-I or a colostrum extract. J. Dairy Sci. 86:1797-1806.
114. Rognstad, R. 1979. Rate-limiting steps in metabolic pathways. J. Biol. Chem. 254:1875-1878.
115. Rohrbeck, D., J. Steinhoff-Wagner, E. Kanitz, and H. M. Hammon. 2012. Effects of colostrum versus formula feeding on hepatic glucocorticoid and α1- and β2-adrenergic receptors in neonatal calves. J. Anim. Sci. 90 (Suppl. 3):301-302.
116. Rufibach, K., N. Stefanoni, V. Rey-Roethlisberger, P. Schneiter, M. G. Doherr, L. Tappy, and J. W. Blum. 2006. Protein synthesis in jejunum and liver of neonatal calves fed vitamin A and lactofer-rin. J. Dairy Sci. 89:3075-3086.
117. Sánchez, J., P. Oliver, O. Miralles, E. Ceresi, C. Picó, and A. Palou. 2005. Leptin orally supplied to neonate rats is directly uptaken by the immature stomach and may regulate short-term feeding. Endocrinology 146:2575-2582.
118. Sánchez, J., T. Priego, M. Palou, A. Tobaruela, A. Palou, and C. Picó. 2008. Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life. Endocrinology 149:733-740.
119. Sangild, P. T. 2001. Transitions in the life of the gut at birth. In: J. E. Lindberg and B. Ogle, editors, Digestive physiology of pigs. CABI Publishing, New York, NY. p. 3-17.
120. Sangild, P. T., R. J. Xu, and J. F. Trahair. 2002. Maturation of intestinal function: The role of cortisol and birth. In: R. Zabielski, P. C. Gregory, and B. Westrom, editors, Biology of the intestine in growing animals. Elsevier, London, UK. p. 111-144.
121. Sauter, S. N., E. Ontsouka, B. Roffler, Y. Zbinden, C. Philipona, M. Pfaffl, B. H. Breier, J. W. Blum, and H. M. Hammon. 2003. Effects of dexamethasone and colostrum intake on the somato-tropic axis in neonatal calves. Am. J. Physiol. 285:E252-E261.
122. Sauter, S. N., B. Roffler, C. Philipona, C. Morel, V. Romé, P. Guilloteau, J. W. Blum, and H. M. Hammon. 2004. Intestinal development in neonatal calves: Effects of glucocorticoids and dependence on colostrum feeding. Biol. Neonate 85:94-104.
123. Savino, F., S. A. Liguori, M. Sorrenti, M. F. Fissore, and R. Oggero. 2011. Breast milk hormones and regulation of glucose homeo-stasis. Int. J. Pediatr. 2011:803985.
124. Scheuer, B. H., Y. Zbinden, P. Schneiter, L. Tappy, J. W. Blum, and H. M. Hammon. 2006. Effects of colostrum feeding and glucocor-ticoid administration on insulin-dependent glucose metabolism in neonatal calves. Domest. Anim. Endocrinol. 31:227-245.
125. Schmidt, M., P. T. Sangild, J. W. Blum, J. B. Andersen, and T. Greve. 2004. Combined ACTH and glucocorticoid treatment improves survival and organ maturation in premature newborn calves. Theriogenology 61:1729-1744.
126. Schubring, C., T. Siebler, J. Kratzsch, P. Englaro, W. F. Blum, K. Triep, and W. Kiess. 1999. Leptin serum concentrations in healthy neonates within the first week of life: Relation to insulin and growth hormone levels, skinfold thickness, body mass index and weight. Clin. Endocrinol. 51:199-204.
127. Silver, M., D. H. Steven, and R. S. Comline. 1973. Placental exchange and morphology in ruminants and the mare. In: R. S. Comline, K. W. Cross, G. S. Dawes, and P. W. Nathanielsz, editors, The Sir Joseph Barcroft century symposium. Foetal and neonatal physiology. Cambridge University Press, London, UK. p. 245-271.
128. Soberon, F., E. Raffrenato, R. W. Everett, and M. E. Van Amburgh. 2012. Preweaning milk replacer intake and effects on long-term productivity of dairy calves. J. Dairy Sci. 95:783-793.
129. Sparks, A. L., J. G. Kirkpatrick, C. S. Chamberlain, D. Waldner, and L. J. Spicer. 2003. Insulin-like growth factor-I and its binding proteins in colostrum compared to measures in serum of Holstein neonates. J. Dairy Sci. 86:2022-2029.
130. Sperling, M. A., S. Ganguli, N. Leslie, and K. Landt. 1984. Fetal-perinatal catecholamine secretion: Role in perinatal glucose ho-meostasis. Am. J. Physiol. 247:E69-E74.
131. Steinhoff-Wagner, J., S. Görs, P. Junghans, R. M. Bruckmaier, E. Kanitz, C. C. Metges, and H. M. Hammon. 2011a. Intestinal glucose absorption but not endogenous glucose production differs between colostrum- and formula-fed neonatal calves. J. Nutr. 141:48-55.
132. Steinhoff-Wagner, J., S. Görs, P. Junghans, R. M. Bruckmaier, E. Kanitz, C. C. Metges, and H. M. Hammon. 2011b. Maturation of endogenous glucose production in preterm and term born calves. J. Dairy Sci. 94:5111-5123.
133. Swiatek, K. R., K. L. Chao, H. L. Chao, M. Cornblath, and J. T. Tildon. 1970. Enzymatic adaptations in newborn pig liver. Biochim. Biophys. Acta 222:145-154.
134. Tildon, J. T., K. R. Swiatek, and M. Cornblath. 1971. Phosphoenolpyruvatecarboxykinase in the developing pig liver. Biol. Neonate 17:436-440.
135. Vacher, P. Y., G. Bestetti, and J. W. Blum. 1995. Insulin-like growth factor I absorption in the jejunum of neonatal calves. Biol. Neonate 68:354-367.
136. Van Kempen, A. A., J. A. Romijn, A. F. Ruiter, M. T. Ackermans, E. Endert, J. H. Hoekstra, J. H. Kok, and H. P. Sauerwein. 2003. Adaptation of glucose production and gluconeogenesis to diminishing glucose infusion in preterm infants at varying gesta-tional ages. Pediatr. Res. 53:628-634.
137. Van Schaftingen, E., and I. Gerin. 2002. The glucose-6-phosphatase system. Biochem. J. 362:513-532.
138. Wang, J., X. Zhu, C. Chen, X. Li, Y. Gao, P. Li, Y. Zhang, M. Long, Z. Wang, and G. Liu. 2012. Effect of insulin-like growth factor-1 (IGF-1) on the gluconeogenesis in calf hepatocytes cultured in vitro. Mol. Cell Biochem. 362:87-91.
139. Xu, R. J., F. Wang, and S. H. Zhang. 2000. Postnatal adaptation of the gastrointestinal tract in neonatal pigs: A possible role of milk-borne growth factors. Livest. Prod. Sci. 66:95-107.
140. Zhang, H. Z., C. Malo, and R. K. Buddington. 1997. Suckling induces rapid intestinal growth and changes in brush border digestive functions of newborn pigs. J. Nutr. 127:418-426.
141. Zierler, K. 1999. Whole body glucose metabolism. Am. J. Physiol. 276:E409-E426.