Glucose and amino acids interact with hormones to control expression of insulin-like growth factor-I and growth hormone receptor mRNA in cultured pig hepatocytes

Journal of Nutrition

Volumn 129, Issue 7, 1999, Pages 1298-1306

  Brameld, John M ^a   Gilmour, R Stewart ^b   Buttery, Peter J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Amino acids; Gene expression; Glucose; Growth hormone receptor; Insulin like growth factor I; Pig hepatocyte

Indexed keywords

AMINO ACID; ARGININE; DEXAMETHASONE; GLUCOSE; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; HORMONE; LIOTHYRONINE; PROLINE; SOMATOMEDIN C; THREONINE; TRYPTOPHAN; VALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; LIVER CELL; MOLECULAR INTERACTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTAKE; REGULATORY MECHANISM; SWINE;

EID: 0032975166     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/129.7.1298     Document Type: Article

References (55)

1. Adams, T. E. (1995) Differential expression of growth hormone receptor messenger RNA from a second promoter. Mol. Cell. Endocrinol. 108: 23-33.
2. Arany, E., Strain, A. J., Hube, M. J., Phillips, I. D. & Hill, D. J. (1993) Interactive effects of nutrients and hormones on the expression of insulin-like growth factor binding protein-1 (IGFBP-1) mRNA and peptide, and IGF-I release from isolated adult rat hepatocytes. J. Cell. Physiol. 155: 426-435.
3. Brameld, J. M. (1997) Molecular mechanisms involved in the nutritional and hormonal regulation of growth in pigs. Proc. Nutr. Soc. 56: 607-619.
4. Brameld, J. M., Atkinson, J. L., Saunders, J. C., Pell, J. M., Buttery, P. J. & Gilmour, R. S. (1996) Effects of growth hormone administration and dietary protein intake on insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) mRNA expression in porcine liver, skeletal muscle and adipose tissue. J. Anim. Sci. 74: 1832-1841.
5. Brameld, J. M., Weller, P. A., Saunders, J. C., Buttery, P. J. & Gilmour, R. S. (1995) Hormonal control of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) mRNA expression by porcine hepatocytes in culture. J. Endocrinol. 146: 239-245.
6. Bruhat, A., Jousse, C., Wang, X.-Z., Ron, D., Ferrara, M. & Fafoumoux, P. (1997) Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J. Biol. Chem. 272: 17588-17593.
7. Buonomo, F. C. & Baile, C. A. (1991) Influence of nutritional deprivation on insulin-like growth factor I, somatotropin, and metabolic hormones in swine. J. Anim. Sci. 69: 755-760.
8. Chomczynski, P. & Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
9. Cohick, W. S. & Clemmons, D. R. (1993) The insulin-like growth factors. Annu. Rev. Physiol. 55: 131-153.
10. Dauncey, M. J., Burton, K. A., White, P., Harrison, A., Gilmour, R. S., Duchamp, C. & Cattaneo, D. (1994) Nutritional regulation of growth hormone receptor gene expression. FASEB J. 8: 81-88.
11. Dudek, S. M. & Semenkovich, C. F. (1995) Essential amino acids regulate fatty acid synthase expression through an uncharged transfer RNA-dependent mechanism. J. Biol. Chem. 270: 29323-29329.
12. Dunnett, C. W. (1955) A multiple comparison procedure for comparing several treatments with a control. Am. Stat. Ass. J. 50: 1096-1121.
13. Foufelle, F., Lepetit, N., Bosc, D., Delzenne, N., Morin, J., Raymondjean, M. & Ferre, P. (1995) DNase 1 hypersensitivity sites and nuclear protein binding on the fatty acid synthase gene: Identification of an element with properties similar to known glucose-responsive elements. Biochem. J. 308: 521-527.
14. Gerlach, J., Brombacher, J., Smith, M. & Neuhaus, P. (1996) High yield hepatocyte isolation from pig livers for investigation of hybrid liver support systems: Influence of collagenase concentration and body weight. J. Surg. Res. 62: 85-89.
15. Harp, J. B., Goldstein, S. & Phillips, L. S. (1991) Nutrition and somatomedin XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytes. Diabetes 40: 95-101.
16. Hillgartner, F. B. & Charron, T. (1998) Glucose stimulates transcription of fatty acid synthase and malic enzyme in avian hepatocytes. Am. J. Physiol. 274: E493-E501.
17. Hoogenboom, L.A.P., Pastoor, F.J.H., Clous, W. E., Hesse, S. E. & Kuiper, H. A. (1989) The use of porcine hepatocytes for biotransformation studies of veterinary drugs. Xenobiotica 19: 1207-1219.
18. Huang, S. & Phillips, L. S. (1996) Identification of an amino acid-responsive element in the rat insulin-like growth factor-I gene. In: The Proceedings of the 10th International Congress of Endocrinology (ICE '96) ( , ed.). pp. 265., San Francisco, CA.
19. Jacoby, D. B., Zilz, N. D. & Towle, H. C. (1989) Sequences within the 5′-flanking region of the S14 gene confer responsiveness to glucose in primary hepatocytes. J. Biol. Chem. 264: 17623-17626.
20. Kang, R., Yamada, K., Tanaka, T., Lu, T. & Noguchi, T. (1996) Relationship between the concentrations of glycolytic intermediates and expression of the L-type pyruvate kinase gene in cultured hepatocytes. J. Biochem. 119: 162-166.
21. Kimball, S. R., Yancisin, M., Horetsky, R. L. & Jefferson, L. S. (1996) Translational and pretranslational regulation of protein synthesis by amino acid availability in primary cultures of rat hepatocytes. Int. J. Biochem. Cell Biol. 28: 285-294.
22. Kuwahata, M., Oka, T., Asagi, K., Kohri, H., Kato, A. & Natori, Y. (1998) Effect of branched-chain amino acids on albumin gene expression in the liver of galactosamine-treated rats. J. Nutr. Biochem. 9: 209-214.
23. LeFrancois-Martinez, A.-M., Diaz-Guerra, M.-J. M., Vallet, V., Kahn, A. & Antoine, B. (1994) Glucose-dependent regulation of the L-pyruvate kinase gene in a hepatoma cell line is independent of insulin and cyclic AMP. FASEB J. 8: 89-96.
24. Li, Q., Chua, M. S. & Semenkovich, C. F. (1998) Properties and purification of a glucose-inducible human fatty acid synthase mRNA-binding protein. Am. J. Physiol. 274: E577-E585.
25. Mariash, C. N., Seelig, S., Schwarte, H. L. & Oppenheimer, J. H. (1986) Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction. J. Biol. Chem. 261: 9583-9586.
26. Marten, N. W., Sladek, F. M. & Straus, D. S. (1996) Effect of dietary protein restriction on liver transcription factors. Biochem. J. 317: 361-370.
27. Miura, Y., Kato, H. & Noguchi, T. (1992) Effect of dietary proteins on insulin-like growth factor-I (IGF-I) messenger ribonucleic acid content in rat liver. Br. J. Nutr, 67: 257-265.
28. Niimi, S., Hayakawa, T., Tanaka, A. & Ichihara, A. (1991) Glucose regulation of growth hormone receptors in primary cultured rat hepatocytes. Endocrinology 129: 2734-2739.
29. Nolten, L. A., Steenbergh, P. H. & Sussenbach, J. S. (1996) The Hepatocyte Nuclear Factor 3β stimulates the transcription of the human insulin-like growth factor I gene in a direct and indirect manner. J. Biol. Chem. 271: 31846-31854.
30. Nolten, L. A., van Schaik, F.M.A., Steenbergh, P. H. & Sussenbach, J. S. (1994) Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBPα and LAP. Mol. Endocrinol. 8: 1636-1645.
31. O'Mahoney, J. V., Brandon, M. R. & Adams, T. E. (1994) Identification of a liver specific promoter for the ovine growth hormone receptor. Mol. Cell. Endocrinol. 101: 129-139.
32. Ogawa, A., Yano, M., Tsujinaka, T., Ebisui, C., Morimoto, T., Kishibuchi, M., Fujita, J., Morita, S., Shiozaki, H. & Monden, M. (1997) Gene expression of albumin and liver-specific nuclear transcription factors in liver of protein-deprived rats. J. Nutr. 127: 1328-1332.
33. Oka, T., Kuwahata, M., Sugitatsu, H., Tsuge, H., Asagi, K., Kohri, H., Horiuchi, S. & Natori, Y. (1997) Modulation of albumin gene expression by amino acid supply in rat liver is mediated through intracellular concentration of pyridoxal 5′-phosphate. J. Nutr. Biochem. 8: 211-216.
34. Pao, C.-I., Farmer, P. K., Begovic, S., Villafuerte, B. C., Wu, G.-J., Robertson, D. G. & Phillips, L. S. (1993) Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding protein 1 gene transcription by hormones and provision of amino acids in rat hepatocytes. Mol. Endocrinol. 7: 1561-1568.
35. Pekhletsky, R. I., Chernov, B. K. & Rubtsov, P. M. (1992) Variants of the 5′-untranslated sequence of human growth hormone receptor mRNA. Mol. Cell. Endocrinol. 90: 103-109.
36. Pell, J. M., Saunders, J. C. & Gilmour, R. S. (1993) Differential regulation of transcription initiation from insulin-like growth factor-I (IGF-I) leader exons and of tissue IGF-I expression in response to changed growth hormone and nutritional status in sheep. Endocrinology 132: 1797-1807.
37. Phillips, L. S., Goldstein, S. & Pao, C.-I. (1991) Nutrition and somatomedin XXVI. Molecular regulation of IGF-I by insulin in cultured rats hepatocytes. Diabetes 40: 1525-1530.
38. Prip-Buus, C., Perdereau, D., Foufelle, F., Maury, J., Ferre, P. & Girard, J. (1995) Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes: Dependency upon glucokinase activity. Eur. J. Biochem. 230: 309-315.
39. Rencurel, F., Waeber, G., Antoine, B., Rocchiccioli, F., Maulard, P., Girard, J. & Leturque, A. (1996) Requirement of glucose metabolism for regulation of glucose transporter type 2 (GLUTZ) gene expression in liver. Biochem. J. 314: 903-909.
40. Saunders, J. C., Dickson, M. C., Pell, J. M. & Gilmour, R. S. (1991) Expression of a growth hormone-responsive exon of the ovine insulin-like growth factor-I gene. J. Mol. Endocrinol. 7: 233-240.
41. Shih, H.-M. & Towle, H. C. (1994) Definition of the carbohydrate response element of the rat S14 gene: Context of the CACGTG motif determines the specificity of carbohydrate regulation. J. Biol. Chem. 269: 9380-9387.
42. Soliman, A. T., Hassan, A. E., Aref, M. K., Hintz, R. L., Rosenfeld, R. G. & Rogol, A.D. (1986) Serum insulin-like growth factors I and II concentrations and growth hormone and insulin responses to arginine infusion in children with protein-energy malnutrition before and after nutritional rehabilitation. Pediatr. Res. 20: 1122-1130.
43. Straus, D. S. & Takemoto, C. D. (1990a) Effect of dietary protein deprivation on insulin-like growth factor (IGF)-I and -II, IGF-binding protein-2; and serum albumin gene expression in rat. Endocrinology 127: 1849-1860.
44. Straus, D. S. & Takemoto, C. D. (1990b) Effect of fasting on insulin-like growth factor-I (IGF-I) and growth hormone receptor mRNA levels and IGF-I gene transcription in rat liver. Mol. Endocrinol. 4: 91-100.
45. Straus, D. S. & Takemoto, C. D. (1991) Specific decrease in liver insulin-like growth factor-I and brain insulin-like growth factor-II gene expression in energy-restricted rats. J. Nutr. 121: 1279-1286.
46. Straus, D. S., Burke, E. J. & Marten, N. W. (1993) Induction of insulin-like growth factor binding protein-1 gene expression in liver of protein-restricted rats and in rat hepatoma cells limited for a single amino acid. Endocrinology 132: 1090-1100.
47. Thissen, J.-P., Pucilowska, J. B. & Underwood, L. E. (1994) Differential regulation of insulin-like growth factor I (IGF-I) and IGF binding protein-1 messenger ribonucleic acids by amino acid availability and growth hormone in rat hepatocyte primary culture. Endocrinology 134: 1570-1576.
48. Torres, N., Martinez, L., Aleman, G., Bourges, H. & Tovar, A. R. (1998) Histidase expression is regulated by dietary protein at the pretranslational level in rat liver. J. Nutr. 128: 818-824.
49. Vance, M. L., Hartman, M. L. & Thomer, M. O. (1992) Growth hormone and nutrition. Horm. Res. 38 (suppl. 1): 85-88.
50. Van Der Meulen, J., Bakker, J.G.M., Smits, B. & De Visser, H. (1997) Effect of source of starch on net portal flux of glucose, lactate, volatile fatty acids and amino acids in the pig. Br. J. Nutr. 78: 533-544.
51. Vaulont, S. & Kahn, A. (1994) Transcriptional control of metabolic regulation genes by carbohydrates. FASEB J. 8: 28-35.
52. Wang, X., Talamantez, J. L. & Adamo, M. L. (1998) A CACCC box in the proximal exon 2 promoter of the rat insulin-like growth factor I gene is required for basal promoter activity. Endocrinology 139: 1054-1066.
53. Weller, P. A., Dauncey, M. J., Bates, P. C., Brameld, J. M., Buttery, P. J. & Gilmour, R. S. (1994) Regulation of porcine insulin-like growth factor-I and growth hormone receptor mRNA expression by energy status. Am. J. Physiol. 266: E776-E785.
54. Weller, P. A., Dickson, M. C., Huskisson, N. S., Dauncey, M. J., Buttery, P. J. & Gilmour, R. S. (1993) The porcine insulin-like growth factor-I gene: characterization and expression of alternate transcription sites. J. Mol. Endocrinol. 11: 201-211.
55. Zheng, Q., Levitsky, L. L., Mink, K. & Rhoads, D. B. (1995) Glucose regulation of glucose transporters in cultured adult and fetal hepatocytes. Metabolism 44: 1553-1558.