Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis

Cell Death and Disease

Volumn 4, Issue 8, 2013, Pages

  Chen, B B ^a,b   Glasser, J R ^a   Coon, T A ^a   Mallampalli, R K ^a,c,d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Drug; Proteolysis; Small molecule; Tumor; Ubiquitin

Indexed keywords

AURORA B KINASE; F BOX LRR REPEAT PROTEIN 2; F BOX PROTEIN; LEUCINE RICH REPEAT KINASE 2; MESSENGER RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CARCINOGENESIS; CELL DEATH; CELL DIVISION; CELL LYSATE; CELL MEMBRANE; CONTROLLED STUDY; GENE OVEREXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TUMOR GROWTH; UBIQUITINATION; UPREGULATION;

ANIMALS; APOPTOSIS; AURORA KINASE B; CARCINOGENESIS; F-BOX PROTEINS; G2 PHASE CELL CYCLE CHECKPOINTS; MICE; MICE, NUDE; POLYPLOIDY; UBIQUITINATION;

EID: 84882581249     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.271     Document Type: Article

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