Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia

Nature Medicine

Volumn 16, Issue 10, 2010, Pages 1120-1127

  Ray, Nancy B ^a   Durairaj, Lakshmi ^a   Chen, Bill B ^b   McVerry, Bryan J ^b   Ryan, Alan J ^a   Donahoe, Michael ^b   Waltenbaugh, Alisa K ^b   O'Donnell, Christopher P ^b   Henderson, Florita C ^a   Etscheidt, Christopher A ^a   McCoy, Diann M ^a   Agassandian, Marianna ^a   Hayes Rowan, Emily C ^b   Coon, Tiffany A ^b   Butler, Phillip L ^a   Gakhar, Lokesh ^a   Mathur, Satya N ^a   Sieren, Jessica C ^a   Tyurina, Yulia Y ^c   Kagan, Valerian E ^c   McLennan, Geoffrey ^a,d   Mallampalli, Rama K ^b,e   more..

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d University of Iowa   (United States)

^e VA Pittsburgh Healthcare System   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BIOLOGICAL MARKER; CALFACTANT; CARDIOLIPIN; CARRIER PROTEIN; COLLECTIN; GALACTOSYLCERAMIDE; GAMMA INTERFERON; GENOMIC DNA; INTERLEUKIN 1BETA; INTERLEUKIN 2; LACTATE DEHYDROGENASE; LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; MUTANT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PROTEIN ATP 8 B1; REGULATOR PROTEIN; SMALL INTERFERING RNA; SULFATIDE; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ATP8B1 PROTEIN, HUMAN; ATP8B1 PROTEIN, MOUSE; LUNG SURFACTANT; PHOSPHOLIPID TRANSFER PROTEIN;

ADENOVIRUS 5; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL PNEUMONIA; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ESCHERICHIA COLI; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE TRANSFER; HAEMOPHILUS INFLUENZAE; HISTOPATHOLOGY; HUMAN; INTERNALIZATION; LIPID ANALYSIS; LIPID TRANSPORT; LUNG ALVEOLUS CELL TYPE 2; LUNG INJURY; LUNG LAVAGE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RNA INTERFERENCE; SURFACE TENSION; ANIMAL; BINDING SITE; C57BL MOUSE; COMPLICATION; DISEASE MODEL; LUNG; METABOLISM; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BINDING SITES; CARDIOLIPINS; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; LUNG; LUNG INJURY; MICE; MICE, INBRED C57BL; PNEUMONIA, BACTERIAL; PULMONARY SURFACTANTS; PHOSPHOLIPID TRANSFER PROTEINS;

BACTERIA (MICROORGANISMS); MUS;

EID: 77957788222     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2213     Document Type: Article

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