Experimental diabetes treated with trigonelline: Effect on key enzymes related to diabetes and hypertension, β-cell and liver function

Molecular and Cellular Biochemistry

Volumn 381, Issue 1-2, 2013, Pages 85-94

  Hamden, Khaled ^a   Bengara, Amel ^b   Amri, Zahra ^b   Elfeki, Abdelfattah ^b  

^a Université de Sfax   (Tunisia)

^b University of Sfax   (Tunisia)

Author keywords

Glucosidase; ACE; Diabetes; DPP 4; Pancreas; Rat; Trigonelline

Indexed keywords

ALPHA GLUCOSIDASE; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL PEPTIDASE IV; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLYCOGEN PHOSPHORYLASE; GLYCOGEN SYNTHASE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; TRIGONELLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; EXPERIMENTAL DIABETES MELLITUS; FENUGREEK; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLYCEMIC CONTROL; GLYCOGEN LIVER LEVEL; HEMOGLOBIN BLOOD LEVEL; HYPERTENSION; INSULIN RELEASE; LIVER FUNCTION; MALE; METABOLISM; NONHUMAN; PANCREAS ISLET BETA CELL; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ALKALOIDS; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; GLYCOGEN; HEMOGLOBIN A, GLYCOSYLATED; HYPERTENSION; INSULIN-SECRETING CELLS; INTESTINES; LIVER; LIVER FUNCTION TESTS; MALE; RATS; RATS, WISTAR;

RATTUS;

EID: 84882581155     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1690-y     Document Type: Article

References (36)

1. Sundaram B, Singhal K, Sandhir R (2012) Ameliorating effect of chromium administration on hepatic glucose metabolism in streptozotocin-induced experimental diabetes. BioFactors 38: 59-68
2. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M (2011) National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378:31-40
3. Schiel R, Müller UA, Beltschikow W, Stein G (2006) Trends in the management of arterial hypertension in patients with type 1 and insulin-treated type 2 diabetes mellitus over a period of 10 years (1989/1990-1994/1995). Results of the JEVIN trial. J Diabetes Complicat 20:273-279
4. Arda-Pirincci P, Bolkent S (2011) The role of glucagon-like peptide-2 on apoptosis, cell proliferation, and oxidant-antioxi-dant system at a mouse model of intestinal injury induced by tumor necrosis factor-alpha/actinomycin D. Mol Cell Biochem 350:13-27
5. Juhl CB, Schmitz O, Pincus S, Holst JJ, Veldhuis J, Pørksen N (2000) Short-term treatment with GLP-1 increases pulsatile insulin secretion in type II diabetes with no effect on orderliness. Diabetologia 43:583-588
6. Ahrén B (2007) GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors. Curr Diabetes Rep 7:340-347
7. Anh Dao TM, Waget A, Klopp P, Serino M, Vachoux C, Pechere L, Drucker DJ, Champion S, Barthe'lemy S, Barra Y, Burcelin R, Seree E (2012) Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic control. PLoS ONE doi:10.1371/journal.pone.0020700
8. Mochida T, Hira T, Hara H (2010) The corn protein, zein hydro-lysate, administered into the ileum attenuates hyperglycemia via its dual action on glucagon-like peptide-1 secretion and dipeptidyl peptidase-IV activity in rats. Endocrinology 151:3095-3104
9. Xia X, Yan J, Shen Y, Tang K, Yin J, Zhang Y, Yang D, Liang H, Ye J, Weng J (2011) Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. PLoS ONE 6:16556
10. Rodriguez-Mateos A, Ishisaka A, Mawatari K, Vidal-Diez A, Jeremy PE, Spencer JPE, Terao J (2012) Blueberry intervention improves vascular reactivity and lowers blood pressure in high-fat-, high-cholesterol-fed rats. doi:10.1017/S0007114512003911
11. Yuan L, Tu D, Ye X, Wu J (2012) Hypoglycemic and hypo-cholesterolemic effects of Coptis chinensis franch inflorescence. Adv Nat Sci 3:1-9
12. Chua M, Baldwin TC, Hocking TJ, Chan K (2010) Traditional uses and potential health benefits of Amorphophallus konjac K. Koch ex N.E. Br J Ethnopharmacol 128:268-278
13. Van Dijk AE, Olthof MR, Meeuse JC, Seebus E, Heine RJ, Van Dam RM (2010) Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. Diabetes Care 32:1023-1025
14. State Administration of Traditional Chinese Medicine (1999) Chinese Materia Medica (II). Shanghai Science and Technology Press, Shanghai, pp 748-749
15. Jiangsu New Medical College Compiled ( 1997) The second volume of dictionary of Chinese medicine. Shanghai People's Publishing House, Shanghai, pp 2370-2371
16. Moorthy R, Prabhu K, Murthy P (1989) Studies on the isolation and effect of orally active hypoglycemic principle from the seeds of fenugreek (Trigonella foenum graecum). Diabetes Bull 9:69-72
17. Mishkinsky J, Joseph B, Sulman FG (1967) Hypoglycaemic effect of trigonelline. Lancet 2:1311-1312
18. van Dijk AE, Olthof MR, Meeuse JC, Seebus E, Heine RJ, van Dam RM (2009) Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. Diabetes Care 32:1023-1025
19. Olthof MR, van Dijk AE, Deacon CF, Heine RJ, van Dam RM (2011) Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones. Nutr Metab 8:1743-7075
20. Zhou J, Zhou S, Zeng S (2013) Experimental diabetes treated with trigonelline: effect on b-cell and pancreatic oxidative parameters. Fund Clin Pharmacol 27(3):279-287. doi: 10.1111/j.1472-8206.2011.01022.x
21. Bakuradze T, Lang R, Hofmann T, Stiebitz H, Bytof G, Lantz I, Baum M, Eisenbrand G, Janzowski C (2010) Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines. Mol Nutr Food Res 54:1734-1743
22. Yoshinari O, Igarashi K (2010) Anti-diabetic effect of trigonel-line and nicotinic acid, on KK-A(y) mice. Curr Med Chem 17:2196-2202
23. Yoshinari O, Sato H, Igarashi K (2009) Anti-diabetic effects of pumpkin and its components, trigonelline and nicotinic acid, on Goto-Kakizaki rats. Biosci Biotechnol Biochem 73:1033-1041
24. Pascual I, Lopéz A, Gómez H, Chappé M, Saroyán A, González Y, Cisneros M, Charli JL, Angeles Chávez M (2007) Screening of inhibitors of porcine dipeptidyl peptidase IV activity in aqueous extracts from marine organisms. Enzym Microb Technol 40:414-419
25. Dahlqvist A (1984) Assay of intestinal disaccharidases. Scand J Clin Lab Investig 44:169-172
26. Cushman DW, Cheung HS (1971) Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem Pharmacol 20:1637-1648
27. Hamden K, Mnafgui K, Belhaj S, Aloulou A, Elfeki A (2013) Inhibition of key digestive enzymes-related to diabetes and hyperlipidemia and protection of liver-kidney functions by trig-onelline in diabetic rats. Sci Pharm 81(1):233-246
28. Olthof MR, Evan Dijk A, Deacon CF, Heine RJ, van Dam RM (2011) Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones. Nutr Metab 8:10
29. Puri D, Prabhu KM, Murthy PS (2002) Mechanism of action of a hypoglycemic principle isolated from fenugreek seeds. Ind J Physiol Pharmacol 46:457-462
30. Raju J, Gupta D, Rao AR, Yadava PK, Baquer NZ (2001) Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes. Mol Cell Biochem 224:45-51
31. Thakran S, Siddiqui MR, Baquer NZ (2004) Trigonella foenum graecum seed powder protects against histopathological abnormalities in tissues of diabetic rats. Mol Cell Biochem 266:151-159
32. Latha M, Pari L (2004) Effect of an aqueous extract of Scoparia dulcis on blood glucose, plasma insulin and some polyol pathway enzymes in experimental rat diabetes. Br J Med Biol Res 37:577-586
33. Ghule AE, Jadhav SS, Bodhankar SL (2012) Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibrosis in streptozotocin induced neonatal diabetic (nSTZ) rats. Int Immunopharmacol 14:740-748
34. Hamden K, Jaouadi B, Salami T, Carreau S, Bejar S, Elfeki A (2010) Modulatory effect of fenugreek saponins on the activities of intestinal and hepatic disaccharidase and glycogen and liver function of diabetic rats. Biotechnol Bioprocess Eng 15:745-753
35. 2+-ATPase (SERCA2) in diabetes. Mol Cell Biochem 376:121-135
36. Pari L, Karthikesan K, Menon VP (2010) Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes. Mol Cell Biochem 341:109-117