Hormesis and Pharmacology

Pharmacology

Volumn , Issue , 2009, Pages 75-102

  Calabrese, Edward ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882467267     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-369521-5.00005-1     Document Type: Chapter

References (138)

1. Alexander L.T. Radioactive materials as plant stimulants-Field results. Agron J 1950, 42:252-255.
2. Andres M.I., Repetto G., Sanz P., Repetto M. Biochemical effects of chlorpromazine on mouse neuroblastoma cells. Vet. Hum. Toxicol. 1999, 41:273-278.
3. Ariens E.J. Affinity and intrinsic. Archives Internationales de Pharmacodynamie 1954, 99:175-187.
4. Ariens E.J., Degroot W.M. Affinity and intrinsic-activity in the theory of competitive inhibition. 3. Homologous decamethonium-derivatives and succinyl-choline-esters. Archives Internationales de Pharmacodynamie et de Therapie 1954, 99:193-205.
5. Ariens E.J., Van Rossum J.M., Simonis A.M. Affinity, intrinsic activity and drug interactions. Pharmacological Reviews 1957, 9:218-236.
6. Ariens E.J., Simonis A.M., Van Rossum J.M. Drug-receptor interaction: Interaction of one or more drugs with one receptor system. Molecular Pharmacology 1964, 119-286. E.J. Ariens (Ed.).
7. Ariens E.J., Simonis A.M., Van Rossum J.M. Drug-receptor interaction: Interaction of one or more drugs with different receptor systems. Molecular Pharmacology 1964, 287-393. Academic Press, New York. E.J. Ariens (Ed.).
8. Barlow R.B. Problems associated with the partiality of a partial agonist. Trends in Pharmacological Sciences 1994, 15:320.
9. Beck B., Slayton T.M., Calabrese E.J., Baldwin L.A., Rudel R. The use of toxicology in the regulatory process. Principles and Methods of Toxicology 2001, 23-75. Taylor & Francis, Philadelphia. 4th ed. A.W. Hayes (Ed.).
10. Bliss C.I. The comparison of dosage-mortality data. The Annals of Applied Biology 1935, 22:307-333.
11. Bliss C.I. The calculation of the dosage-mortality curve. The Annals of Applied Biology 1935, 22:134-167.
12. Brain P., Cousens R. An equation to describe dose-responses where there is stimulation of growth at low doses. Weed Res. 1989, 29:93-96.
13. Branham S.E. The effects of certain chemical compounds upon the course of gas production by baker's yeast. Journal of Bacteriology 1929, 18:247-284.
14. Brenchley W.E. Inorganic Plant Poisons and Stimulants 1914, Cambridge University Press, London.
15. Bryan W.R., Shimkin M.D. Quantitative analysis of dose-response data obtained with three carcinogenic hydrocarbons in strain C3H male mice. Journal of the National Cancer Institute 1943, 3:503-531.
16. Buchanan R.E., Fulmer E.I. Physiology and Biochemistry of Bacteria. Vol. II. Effects of Environment Upon Microorganisms 1930, The Williams and Wilkins Company, Baltimore, MD.
17. Calabrese E.J. Paradigm lost, paradigm found: The re-emergence of hormesis as a fundamental dose response model in the toxicological sciences. Environmental Pollution 2005, 138:378-411.
18. Calabrese E.J. Hormetic dose-response relationships in immunology: Occurrence, quantitative feature of the dose response, mechanistic foundations, and clinical implications. Critical Reviews in Toxicology 2005, 35:89-295.
19. Calabrese E.J. Cancer biology and hormesis: Human tumor cell lines commonly display hormetic (biphasic) dose responses. Critical Reviews in Toxicology 2005, 35:463-582.
20. Calabrese E.J. Historical blunders: How toxicology got the dose-response relationship half right. Cellular and Molecular Biology 2005, 51:643-654.
21. Calabrese E.J. Hormesis: From marginalization to mainstream. A case for hormesis as the default dose-response model in risk assessment. Toxicology and Applied Pharmacology 2004, 197:125-136.
22. Calabrese E.J. Special issue: Hormesis: Environmental and biomedical perspectives-Introduction. Critical Reviews in Toxicology 2003, 33(3-4):213-214.
23. Calabrese E.J. Overcompensation stimulation: A mechanism for hormetic effects. Critical Reviews in Toxicology 2001, 31:425-470.
24. Calabrese E.J., Baldwin L.A. Toxicology rethinks its central belief-Hormesis demands a reappraisal of the way risks are assessed. Nature 2003, 421(6924):691-692.
25. Calabrese E.J., Baldwin L.A. Hormesis: The dose-response revolution. Annual Review of Pharmacology and Toxicology 2003, 43:175-197.
26. Calabrese E.J., Baldwin L.A. Hormesis at the National Toxicology Program (NTP): Evidence of hormetic dose responses in NTP dose-range studies. Nonlinearity Biol Toxicol Med 2003, 1:455-467.
27. Calabrese E.J., Baldwin L.A. The hormetic dose response model is more common than the threshold model in toxicology. Toxicological Sciences 2003, 71(2):246-250.
28. Calabrese E.J., Baldwin L.A. Defining hormesis. Human & Experimental Toxicology 2002, 21:91-97.
29. Calabrese E.J., Baldwin L.A. Hormesis: A generalizable and unifying hypothesis. Critical Reviews in Toxicology 2001, 31:353-424.
30. Calabrese E.J., Baldwin L.A. Hormesis: U-shaped dose-response and their centrality in toxicology. Trends in Pharmacological Sciences 2001, 22(6):285-291.
31. Calabrese E.J., Baldwin L.A. The frequency of U-shaped dose-responses in the toxicological literature. Toxicological Sciences 2001, 62:330-338.
32. Calabrese E.J., Baldwin L.A. Agonist concentration gradients as a generalizable regulatory implementation strategy. Critical Reviews in Toxicology 2001, 31:471-474.
33. Cedergreen N., Ritz C., Streibig J.C. Improved empirical models describing hormesis. Env. Toxicol. Chem. 2005, 24:3166-3172.
34. Calabrese E.J., Baldwin L.A. The dose determines the stimulation (and poison): Development of a chemical hormesis database. Intern'tl. J. Toxicol. 1997, 16:545-559.
35. Calabrese E.J., Blain R. The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview. Toxicol. Appl. Pharmacol. 2005, 202:289-301.
36. Clark A.J. Applied Pharmacology 1926, 430. J & A Churchill, London. 1st ed.
37. Clark A.J. Handbook of Experimental Pharmacology 1937, Verlig Von Julius Springer, Berlin.
38. Clark A.J. Mode of Action of Drugs on Cells 1933, Arnold, London.
39. Cokkinos D.V. Preconditioning-A paradigm of yin and yang. Hellenic Journal of Cardiology: HJC = Hellenike Kardiologike Epitheorese 2002, 43:179-182.
40. Dale H.H. On some physiological actions of ergot. The Journal of Physiology (London) 1906, 34:163-206.
41. Davies J.M.S., Lowry C.V., Davies K.J.A. Transcient adaptation to oxidative stressing yeast. Archives of Biochemistry and Biophysics 1995, 317:1-6.
42. Davis J.M., Svensgaard D.J. U-shaped dose-response curves - their occurrence and implications for risk assessment. J. Toxicol. Env. Health 1990, 30:71-83.
43. Duggar B.M. Aureomycin-A product of the continuing search for new antibiotics. Annals of the New York Academy of Sciences 1948, 51:177.
44. Eaton D.L., Klaassen C.D. Principles of toxicology, Chapter 2. Casarett & Doull's Essentials of Toxicology 2003, 6-20.
45. Flood J.F., Smith G.E., Cherkin A. 2-drug combinations of memory enhancers-Effect of dose ratio upon potency and therapeutic window, in mice. Life Sciences 1988, 42:2145-2154.
46. Flood J.F., Smith G.E., Cherkin A. Memory enhancement-Supra-additive effect of subcutaneous cholinergic drug-combinations in mice. Psychopharmacology 1985, 86:61-67.
47. Flood J.F., Smith G.E., Cherkin A. Memory retention-Potentiation of cholinergic drug-combinations in mice. Neurobiology of Aging 1983, 4:37-43.
48. Furchgott R.F. The pharmacology of vascular smooth muscle. Pharmacological Reviews 1955, 7:183-265.
49. Gaddum J.H. The quantitiative effects of antagonistic drugs. The Journal of Physiology 1936, 89:79.
50. Gaddum J.H. Theories of drug antagonism. Pharmacological Reviews 1957, 9:211-268.
51. Gaddum J.H. Methods of biological assay depending on the quantal response. Med Res Counc Ond Sp Rep Ser No 183 1933, H.M. Stationery Office, London.
52. Gaddum J.H. The pharmacologists of Edinburgh. Ann Rev 1962, 2:1-10.
53. Garant D.S., Xu S.G., Sperber E.F., Moshe S.L. Age-related differences in the effects of GABAA agonists microinjected into rat substantia nigra: Pro- and anticonvulsant actions. Epilepsia 1995, 36:960-965.
54. Heald F.D. On the toxic effect of dilute solutions of acids and salts upon plants. Bot Gaz 1896, 22:125-153.
55. Hektoen L. Further studies on the effects of roentgen ray on antibody-production. The Journal of Infectious Diseases 1918, 22:28-33.
56. Hektoen L. Further observations on the effects of roentegenization and splenectomy on antibody production. The Journal of Infectious Diseases 1920, 27:23-30.
57. Henschler D. The origin of hormesis: Historical background and driving forces. Human & Experimental Toxicology 2006, 25:347-351.
58. Honar H., Riazi K., Homayoun H., Sadeghipour H., Rashidi N., Ebrahimkhani M.R., et al. Ultra-low dose naltrexone potentiates the anti-convulsant effect of low dose morphine on clonic seizure. Neuroscience 2004, 129:733-742.
59. Hotchkiss M. Studies on salt actions. VI. The stimulating and inhibitive effect of certain cations upon bacteria growth. Journal of Bacteriology 1923, 8:141-162.
60. Hussar D.A. Mechanisms of drug interactions. Journal of the American Pharmaceutical Association 1969, 9:208.
61. Jarv J. An alternative model for model-shaped concentration response curve. Trends in Pharmacological Sciences 1994, 15:321.
62. Jarv J., Toomela T., Karelson E. Dual effect of carbachol on muscarinic receptor. Biochemistry and Molecular Biology International 1993, 30:649-654.
63. Jensen G.H. Toxic limits and stimulation effects of some salts and poisons on wheat. Bot Gaz 1907, 43:11-44.
64. Josephs I. Holzknecht. Radiology 1931, 17:1316-1318. Professor Doctor.
65. Kahlenberg L., True R.H. On the toxic action of dissolved salts and their electrolytic dissociation. Bot Gaz 1896, 22:81-124.
66. Laughlin R.B., Ng J., Guard H.E. Hormesis-A response to low environmental concentrations of petroleum-hydrocarbons. Science 1981, 211:705-707.
67. Leuchenko A., Bruck J., Sternberg P.W. Regulatory modules that generate biphasic signal response in biological systems. Systematic Biology 2004, 1:139-148.
68. Lipman C.B. Toxic and antagonistic effects of salts as related to ammonification by Bacillus Subtilis. Bot Gaz 1909, 48:105-125.
69. Lipman C.B. Letter of C.B. Lipman concerning injuries by metals in the soil to the Selby Smelter Commission. Department of the Interior, Bureau of Mines, Bull. 1915, 98:466-467. Washington Government Printing Office.
70. Luckey T.D. Ionizing Radiation and Hormesis 1980, CRC Press, Boca Raton.
71. Luckey T.D. Radiation Hormesis 1991, CRC Press, Inc, Boca Raton.
72. Middler S., Pak C.Y., Murad F., Bartter F.C. Thiazide diuretics and calcium metabolism. Metabolism: Clinical and Experimental 1973, 22:139-146.
73. Miller W.M., Green C.A., Kitchin H. Biphasic action of penicillin and other sulphonamide similarity. Nature 1945, 1:210-211.
74. Murry C.E., Jennings R.B., Reimer K.A. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation 1986, 75:1124-1136.
75. Mutscheller A. Physical standards of protection against Roentgen ray dangers. AJR. American Journal of Roentgenology 1925, 13:65-69.
76. Oliva A., Meepagala K.M., Wedge D.E., Harries D., Hale A.L., Aliotta G., et al. Natural fungicides from Ruta graveolens L. leaves, including a new quinolone alkaloid. Journal of Agricultural and Food Chemistry 2003, 51:890-896.
77. Paton W.D.M. A theory of drug action based on the rate of drug-receptor combinations. Proceedings of the Royal Society of London, Series B 1961, 154:21-69.
78. Paton W.D.M., Perry W.C.M. The relationship between depolarization and block in the cat's superior cervical ganglion. The Journal of Physiology 1953, 119:43-57.
79. Quirk S.J., Funder J.W. Steroid receptors, and the generation of closely coupled/biphasic dose response curves. Journal of Steroid Biochemistry 1988, 30:9-15.
80. Ray W.A., Downey W., Griffin M.R., Melton L.J. Long-term use of thiazide diuretics and risk of hip fracture. Lancet 1989, (I):687-690.
81. Robison G.A. Forward. Towards Understanding Receptors 1981, v-x. Elsevier/North-Holland, New York. J.W. Lamble (Ed.).
82. Rovati G.E., Nicosia S. Lower efficacy: Interaction with an inhibitory receptor or partial agonism?. Trends in Pharmacological Sciences 1994, 15:140-144.
83. Samson L., Cairns J. A new pathway for DNA in Escherichia coli. Nature 1977, 267:281-283.
84. Salle A.J. Fundamental Principles of Bacteriology 1939, 317-338. McGraw-Hill Book Company, Inc, New York.
85. Salsburg D. The Lady Tasting Tea. How Statistics Revolutionized Science in the Twentieth Century 2001, 75-77. W.H. Freeman and Company, New York.
86. Schackell L.F. The relation of dosage to effect. II. The Journal of Pharmacology and Experimental Therapeutics 1925, 25:275-288.
87. Schackell L.F. Studies in protoplasm poisoning. I. Phenols. The Journal of General Physiology 1923, 5:783-805.
88. Schulz H. UBer Hefegifte. Pflugers Archiv. Fue die gesamte Physiologie des Menschen und der Tiere 1888, 42:517-541.
89. Smith E.C. Effects of ultra-violet radiation and temperature on Fusarium. II. Stimulation. Bull Tor Bot Club 1935, 62:151-164.
90. Smyth H.F. Sufficient Challenge. Food and Cosmetics Toxicology 1967, 5:51-58.
91. Southam C.M., Erlich J. Effects of extracts of western red-cedar heartwood on certain wood-decaying fungi in culture. Phytopathology 1943, 33:517-524.
92. Stebbing A.R.D. Hormesis-The stimulation of growth by low levels of inhibitors. Sci Tot Env 1982, 22:213-234.
93. Stephenson R.P. A modification of receptor theory. British Journal of Pharmacology 1956, 11:379-393.
94. Stolman A. Combined action of drugs with toxicological implications. Part I. Progress in Chemical Toxicology 1967, 3:305-361.
95. Stolman A. Combined action of drugs with toxicological implications. Part II. Progress in Chemical Toxicology 1969, 48:257-395.
96. Szabadi E. A model of two functionally antagonistic receptor populations activated by the same agonist. Journal of Theoretical Biology 1977, 69:101-112.
97. Taliaferro W.H., Taliaferro L.G. Effect of x-rays on immunity: A review. Journal of Immunology (Baltimore, Md.: 1950) 1951, 66:181-212.
98. Van Ewijk P.H., Hoekstra J.A. Calculation of the EC50 and its confidence interval when subtoxic stimulus is present. Ecotoxicology and Environmental Safety 1993, 23:25-32.
99. Verney E.B., Barcroft J. A.J. Clark (Obituary). Obituary Notices of Fellows of the Royal Society 1941, 3:969.
100. Warren S. The histopathology of radiation lesions. Physiological Review 1945, 25:225-238.
101. Wilder J. The "law of initial values," a neglected biological law and its significance for research and practice. Psychophysiology 1931/1976, 38-46. Dowden, Hutchinson & Ross, Inc, Stroudsburg, PA, Translated from Zeitschrift fur die gesamte Neurologie und Psychiatrie 137: 317-338. S.W. Proges, M.G.H. Coles (Eds.).
102. Wilder J. Stimulus and Response: The Law of Initial 1967, Wright, Bristol, Value, 25.
103. Winslow C.E.A., Dolloff A.F. Relative importance of additive and antagonistic effects of cations upon bacterial viability. Journal of Bacteriology 1928, 15:67-92.
104. Zell-Stimulations-Forschungen 1924-1930, Vol. 1-3. Paul Pare, Berlin. M. Popoff, W. Gleisberg (Eds.).
105. Zimmerman F.T., Burgemeister B.B., Putnam T.J. The ceiling effect of glutamic acid upon intelligence in children and in adolescents. The American Journal of Psychology 1948, 104:593-599.
106. Bonnet M., Lespinats G., Burtin C. Histamine and serotonin suppression of lymphocyte response to phytohemagglutinin and allogeneic cells. Cell. Immunol. 1984, 83:280-291.
107. Elferink J.G.R., De Koster B.M. Endothelin-induced activation of neutrophil migration. Biochem. Pharmacol. 1994, 48(5):865-871.
108. Boyd J.G., Gordon T. A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor. European Journal of Neuroscience 2002, 15:613-626.
109. Elferink J.G.R., DeKoster B.M. The effect of thimerosal on neutrophil migration. A comparison with the effect on calcium mobilization and CD11B expression. Biochem. Pharmacol. 1998, 55(3):305-312.
110. Conti A.M., Fischer S.J., Windebank A.J. Inhibition of axonal growth from sensory neurons by excess nerve growth factor. Ann. Neurol. 1977, 42:838-846.
111. Pfeifer R.W., Patterson R.M. Modulation of lectin-stimulated lymphocyte agglutination and mitogenesis by estrogen metabolites: Effects on early events of lymphocyte activation. Acrch. Toxicol. 1986, 58:157-164.
112. Wanger H., Kreher B., Jurcic K. In vitro stimulation of human granulocytes and lymphocytes by pico- and femtogram quantities of cytostatic agents. Drug Res. 1988, 38(1):273-275.
113. Williamson S.A., Knight R.A., Lightman S.L., Hobbs J.R. Differential effects of beta-endorphin fragments on human natural killing. Brain, Behav. Immun. 1987, 1:329-335.
114. Hsu J-T., Hung H-C., Chen C-J., Hsu W-L., Ying C. Effects of the dietary phytoestrogen biochanin A on cell growth in the mammary carcinoma cell line MCF-7. J. Nutr. Biochem. 1999, 10:510-517.
115. Costall B., Jones B.J., Kelly M.E., Naylor R.J., Tomkins D.M. Exploration of mice in a black and white test box: Validation as a model of anxiety. Pharmacol. Biochem. Behav. 1989, 32:777-785.
116. Kawamoto T., Sato J.D., Jonathan A.L., Polikoff J., Sato G.H., Mendelsohn J. Growth stimulation of A432 cells by epidermal growth factor: Identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibidy. Proc. Nat. Acad Sci. 1983, 80:1337-1341.
117. Love-Schimenti C.D., Gibson F.C.D., Ratnam A.V., Bikle D.D. Antiestrogen potentiation of antiproliferative effects of vitamin D3 analogues in breast cancer cells. Cancer Res. 1996, 56:2789-2794.
118. Crabbe J.C., Gallaher E.J., Cross S.J., Belknap J.K. Genetic Determinants of Sensitivity to Diazepam in Inbred Mice. Behav. Neurosci. 1998, 112(3):668. 667.
119. Cookson M.R., Mead C., Austwick S.M., Pentreath V.W. Use of the MTT assay for estimating toxicity in primary astrocyte and C6 glioma cell cultures. Toxic. In Vitro 1995, 9:39-48.
120. Daston G.P., Rogers J.M., Versteeg D.J., Sabourin T.D., Baines D., Marsh S.S. Interspecies Comparisons of A/D Ratios: A/D Ratios are not Constant Across Species. Fund. Appl. Toxicol. 1991, 17:696-722.
121. Fulder S.J. The Growth of Cultured Human Fibroblasts Treated with Hydrocortisone and Extracts of the Medicinal Plant Panax ginseng. Exp. Geront. 1977, 12:125-131.
122. Ji L., Melkonian G., Riveles K., Talbot P. Identification of pyridine compounds in cigarette smoke solution that inhibit growth of the chick chorioallantoic membrane. Toxicol. Sci. 2002, 69:217-225.
123. Miller W.M., Green C.A., Kitchin H. Biphasic Action of Penicillin and Other Sulphonamide Similarity. Nature 1945, 1(155):210-211.
124. +-ATPase activity in rats. Toxicology 2005, 215:191-197.
125. Varlinskaya E.I., Spear L.P., Spear N. Acute effects of ethanol on behavior of adolescent rats: Role of social context. Alcoholism:Clin. Exper. Res. 2001, 25(3):377-385.
126. Frizzo M.E., Dall'Onder L.P., Dalcin K.B., Souza D.O. Riluzole Enhances Glutamate Uptake in Rat Astrocyte Cultures. Cell. Mol. Neurobiol. 2004, 24(1):123-128.
127. Von Zglinicki T., Edwall C., Ostlund E., Lind B., Nordberg M., Ringertz N.R., Wroblewski J. Very Low Cadmium Concentrations Stimulate DNA Synthesis and Cell Growth. J. Cell Sci. 1992, 103(4):1073-1081.
128. 1-selective adenosine agonist in porcine coronary artery: involment of potassium channels. J. Pharmacol. Exp. Ther. 1992, 260:437-443.
129. Hidalgo E., Dominquez C. Growth-altering effects of sodium hypochlorite in cultured human dermal fibroblasts. Life Sci. 2000, 67:1331-1344.
130. Cicero T.J., Badger T.M. Effects of alcohol on the hypothalamic-pituitary-gonadal axis in the male rat. J. Pharmacol. Exp. Ther. 1977, 201:427-433.
131. Voss A.K., Fortune J.E. Estradiol-17-b has a biphasic effect on oxytocin secretion by bovine granulose cells. Biol. Reprod. 1993, 48:1404-1409.
132. Tang L., Mamotte C.D.S., Van Bockxmeer F.M., Taylor R.R. The effect of homocysteine on DNA synthesis in cultured human vascular smooth muscle. Atherosclerosis 1998, 136:169-173.
133. Frizzo M.E., Dall'Onder L.P., Dalcin K.B., Souza D.O. Riluzole Enhances Glutamate Uptake in Rat Astrocyte Cultures. Cell. Mol. Neurobiol. 2004, 24(1):123-128.
134. Lee C., Sutkowski D.M., Sensibar J.A., Zelner D., Kim I., Amsel I., Shaw N., Prins G.S., Kozlowski J.M. Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. Endocrinology 1995, 136:796-803.
135. Ying C., Hsu J.-T., Hung H.-C., Lin D.-H., Chen L-F.O., Wang L-K. Growth and cell cycle regulation by isoflavones in human breast carcinoma cells. Reprod. Nutr. Dev. 2002, 42:55-64.
136. Abe K., Sekizawa T., Kogure K. Biphasic effects of chlorpromazine on cell viability in a neuroblastoma cell line. Neurosci. Letters 1986, 71:335-339.
137. Bernhard D., Schwaiger W., Crazzolara R., Tinhofer I., Kofler R., Csordas A. Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells. Cancer Letters 2003, 195:193-199.
138. Garant D.S., Xu S.G., Sperber E.F., Moshe S.L. Age-related differences in the effects of GABAA agonists microinjected into rat substantia nigra: pro- and anticonvulsant actions. Epilepsia 1995, 36:960-965.