Identification of pyridine compounds in cigarette smoke solution that inhibit growth of the chick chorioallantoic membrane

Toxicological Sciences

Volumn 69, Issue 1, 2002, Pages 217-225

  Ji, Lin ^a   Melkonian, Goar ^a   Riveles, Karen ^a   Talbot, Prue ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

3 ethylpyridine; Active smoking; Chick chorioallantoic membrane; Cigarette smoke; Growth; Passive smoking; Pyridine; Pyridine derivative

Indexed keywords

BROXURIDINE; CIGARETTE SMOKE; COSMETIC; METHYL GROUP; PYRIDINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; ASSAY; CELL PROLIFERATION; CHICKEN; CHORIOALLANTOIS; CONTROLLED STUDY; FOOD; GAS CHROMATOGRAPHY; HEALTH HAZARD; HYPOTHESIS; MASS SPECTROMETRY; NONHUMAN; SOLID PHASE EXTRACTION; TISSUE GROWTH; TOBACCO; TOXICITY TESTING;

ANIMALS; ANTIMETABOLITES; BROMODEOXYURIDINE; CHICK EMBRYO; CHORION; CULTURE MEDIA; DEPRESSION, CHEMICAL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INDICATORS AND REAGENTS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PYRIDINES; PYRROLES; SMOKE; STRUCTURE-ACTIVITY RELATIONSHIP; TOBACCO;

ANIMALIA; GALLUS GALLUS; NICOTIANA TABACUM;

EID: 0036740128     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/69.1.217     Document Type: Article

References (22)

1. Albaugh, G., Kann, B., Strande, L., Vemulapalli, P., Hewitt, C., and Alexander, J. B. (2001). Nicotine induces endothelial TNF-α expression, which mediates growth retardation in vitro. J. Surg. Res. 99, 381-384.
2. Brunneman, K. D., Stahnke, G., and Hoffman, D. (1978). Chemical studies on tobacco smoke. LXI. Volatile pyridines: Quantitative analysis in mainstream and sidestream smoke of cigarettes and cigars. Anal. Lett. A11, 545-560.
3. Findlay, J. K. (1986). Angiogenesis in reproductive tissues. J. Endrocrinol. 111, 357-366.
4. Frick, W. G., and Seals, R. R., Jr. (1994). Smoking and wound healing: A review. Tex. Dent. J. 111, 21-23.
5. Genbacev, O., McMaster, M. T., Lazic, J., Nedeljkovic, S., Cvetkovic, M., Joslin, R., and Fisher, S. J. (2000). Concordant in situ and in vitro data show that maternal cigarette smoking negatively regulates placental cytotrophoblast passage through the cell cycle. Reprod. Toxicol. 14, 495-506.
6. Heeschen, C., Jang, J. J., Weis, M., Pathak, A., Kaji, S., Hu, R. S., Tsao, P. S., Johnson, F. L., and Cooke, J. P. (2001). Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis. Nat. Med. 7, 833-839.
7. Knoll, M., and Talbot, P. (1998). Cigarette smoke inhibits oocyte cumulus complex pick-up by the oviduct in vitro independent of ciliary beat frequency. Reprod. Toxicol. 12, 57-68.
8. Ma, L., Chow, J. Y., and Cho, C. H. (1999). Cigarette smoking delays ulcer healing: Role of constitutive nitric oxide synthase in rat stomach. Am. J. Physiol. 276, G238-G248.
9. Ma, L., Wang, W. P., Chow, J. Y., Yuen, S. T., and Cho, C. H. (2000). Reduction of EGF is associated with the delay of ulcer healing by cigarette smoking. Am. J. Physiol. Gastrointest. Liver Physiol. 278, G10-G17.
10. Magers, T., Talbot, P., DiCarlantonio, G., Knoll, M., Demers, D., Tsai, I., and Hoodbhoy, T. (1995). Cigarette smoke inhalation affects the reproductive system of female hamsters. Reprod. Toxicol. 9, 513-525.
11. Martin, T. R., and Bracken, M. B. (1986). Association of low birth weight with passive smoke exposure in pregnancy. Am. J. Epidemiol. 124, 633-642.
12. Melkonian, G., Cheung, L., Marr, R., Tong, C., and Talbot, P. (2002a). Mainstream and sidestream cigarette smoke inhibit growth and angiogenesis in the day 5 chick chorioallantoic membrane. Toxicol. Sci. 68, 237-248.
13. Melkonian, G., Le, C., Zheng, W., Talbot, P., and Martins-Green, M. (2000). Normal patterns of angiogenesis and extracellular matrix deposition in chick chorioallantoic membranes are disrupted by mainstream and sidestream cigarette smoke. Toxicol. Appl. Pharmacol. 163, 26-37.
14. Melkonian, G., Munoz, N., Chung, J., Tong, C., Marr, R., and Talbot, P. (2002b). Capillary plexus development in the day 5-day 6 chick chorioallantoic membrane is inhibited by cytochalasin D and suramin. J. Exp. Zool. 292, 241-254.
15. R. J. Reynolds Tobacco Company. Cigarette Ingredients. Available at: http://www.rjrt.com/T12/Pages/TIciggred≻mmary.asp. Accessed July 12, 2002.
16. Silverstein, P. (1992). Smoking and wound healing. Am. J. Med. 93, 22S-24S.
17. Stillman, R. J., Rosenberg, M. J., and Sachs, B. P. (1986). Smoking and reproduction. Fertil. Steril. 46, 545-566.
18. Talbot, P., DiCarlantonio, G., Knoll, M., and Gomez, C. (1998). Identification of cigarette smoke components that alter functioning of hamster (Mesocricetus auratus) oviducts in vitro. Biol. Reprod. 58, 1047-1053.
19. Tuormaa, T. E. (1995). The adverse effects of tobacco smoking on reproduction and health: A review from the literature. Nutr. Health 10, 105-120.
20. U.S. EPA. (1992). Respiratory health effects of passive smoking: Lung cancer and other disorders. EPA Report/600/6-90/006F. U.S. Environmental Protection Agency, Washington, DC.
21. U.S. FDA. EAFUS: A Food Additive Database. U.S. Food and Drug Administration. Available at: http://www.cfsan.fda.gov/~dms/eafus.html. Accessed July 12, 2002.
22. Villablanca, A. C. (1998). Nicotine stimulates DNA synthesis and proliferation in vascular endothelial cells in vitro. J. Appl. Physiol. 84, 2089-2098.