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Volumn 9, Issue 9, 2013, Pages 1139-1153

Glycine conjugation: Importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation

Author keywords

Acyl coenzyme A; Benzoate; CASTOR disorder; Coenzyme A; Coenzyme A sequestration; GLYAT; Glycine conjugation; Glycine N acyltransferase; Hepatocellular carcinoma; Xenobiotics

Indexed keywords

ACYL COENZYME A; BENZOIC ACID; GLYCINE; LONG CHAIN FATTY ACID COENZYME A LIGASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

EID: 84882386100     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2013.796929     Document Type: Review
Times cited : (55)

References (101)
  • 1
    • 34548247413 scopus 로고
    • On gouty concretions; With a new method of treatment
    • Ure A. On gouty concretions; with a new method of treatment. Pharm J Trans 1841;1:24
    • (1841) Pharm J Trans , vol.1 , pp. 24
    • Ure, A.1
  • 2
    • 84862796969 scopus 로고
    • On the conversion of benzoic acid into hippuric acid
    • Keller W. On the conversion of benzoic acid into hippuric acid. Prov Med J Retrosp Med Sci 1842;4(13):256-7
    • (1842) Prov Med J Retrosp Med Sci , vol.4 , Issue.13 , pp. 256-257
    • Keller, W.1
  • 3
    • 34547154782 scopus 로고    scopus 로고
    • Amino acid conjugation: Contribution to the metabolism and toxicity of xenobiotic carboxylic acids
    • Knights KM, Sykes MJ, Miners JO. Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids. Expert Opin Drug Metab Toxicol 2007;3(2):159-68
    • (2007) Expert Opin Drug Metab Toxicol , vol.3 , Issue.2 , pp. 159-168
    • Knights, K.M.1    Sykes, M.J.2    Miners, J.O.3
  • 5
    • 1542791542 scopus 로고    scopus 로고
    • Glucuronidation and susceptibility to chemical carcinogenesis
    • Wallig MA. Glucuronidation and susceptibility to chemical carcinogenesis. Toxicol Sci 2004;78(1):1-2
    • (2004) Toxicol Sci , vol.78 , Issue.1 , pp. 1-2
    • Wallig, M.A.1
  • 6
    • 79953655654 scopus 로고    scopus 로고
    • Drug-S-acyl-glutathione thioesters: Synthesis, bioanalytical properties, chemical reactivity, biological formation and degradation
    • Grillo MP. Drug-S-acyl-glutathione thioesters: synthesis, bioanalytical properties, chemical reactivity, biological formation and degradation. Curr Drug Metab 2011;12(3):229-44
    • (2011) Curr Drug Metab , vol.12 , Issue.3 , pp. 229-244
    • Grillo, M.P.1
  • 7
    • 1642457324 scopus 로고    scopus 로고
    • In vitro reactivity of carboxylic acid-CoA thioesters with glutathione
    • Sidenius U, Skonberg C, Olsen J, Hansen SH. In vitro reactivity of carboxylic acid-CoA thioesters with glutathione. Chem Res Toxicol 2004;17:75-81
    • (2004) Chem Res Toxicol , vol.17 , pp. 75-81
    • Sidenius, U.1    Skonberg, C.2    Olsen, J.3    Hansen, S.H.4
  • 8
    • 33746906722 scopus 로고    scopus 로고
    • Heme in intestinal epithelial cell turnover, differentiation, detoxifi cation, infl ammation, carcinogenesis, absorption and motility
    • Oates PS, West AR. Heme in intestinal epithelial cell turnover, differentiation, detoxifi cation, infl ammation, carcinogenesis, absorption and motility. World J Gastroenterol 2006;12(27):4281-95
    • (2006) World J Gastroenterol , vol.12 , Issue.27 , pp. 4281-4295
    • Oates, P.S.1    West, A.R.2
  • 9
    • 84855197142 scopus 로고    scopus 로고
    • In silico prediction of acyl glucuronide reactivity
    • Potter T, Lewis R, Luker T, et al. In silico prediction of acyl glucuronide reactivity. J Comput Aided Mol Des 2011;25:997-1005
    • (2011) J Comput Aided Mol des , vol.25 , pp. 997-1005
    • Potter, T.1    Lewis, R.2    Luker, T.3
  • 10
  • 12
    • 41949122731 scopus 로고    scopus 로고
    • Hereditary and acquired diseases of acyl-coenzyme A metabolism
    • Mitchell GA, Gauthier N, Lesimple A, et al. Hereditary and acquired diseases of acyl-coenzyme A metabolism. Mol Genet Metab 2008;94(1):4-15
    • (2008) Mol Genet Metab , vol.94 , Issue.1 , pp. 4-15
    • Mitchell, G.A.1    Gauthier, N.2    Lesimple, A.3
  • 13
    • 33947241895 scopus 로고    scopus 로고
    • Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme a homeostasis
    • Zhang Y, Chohnan S, Virga KG, et al. Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme a homeostasis. Chem Biol 2007;14(3):291-302
    • (2007) Chem Biol , vol.14 , Issue.3 , pp. 291-302
    • Zhang, Y.1    Chohnan, S.2    Virga, K.G.3
  • 15
    • 0031663753 scopus 로고    scopus 로고
    • Role of hepatic fatty acid: Coenzyme A ligases in the metabolism of xenobiotic carboxylic acids
    • Knights KM. Role of hepatic fatty acid: coenzyme A ligases in the metabolism of xenobiotic carboxylic acids. Clin Exp Pharmacol Physiol 1998;25:776-82
    • (1998) Clin Exp Pharmacol Physiol , vol.25 , pp. 776-782
    • Knights, K.M.1
  • 16
    • 0000336221 scopus 로고
    • Benzoyl coenzyme A and hippurate synthesis
    • Schachter D, Taggart JV. Benzoyl coenzyme A and hippurate synthesis. J Biol Chem 1953;203:925-34
    • (1953) J Biol Chem , vol.203 , pp. 925-934
    • Schachter, D.1    Taggart, J.V.2
  • 17
    • 11144220062 scopus 로고    scopus 로고
    • Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family
    • Mashek DG, Bornfeldt KE, Coleman RA, et al. Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. J Lipid Res 2004;45:1958-61
    • (2004) J Lipid Res , vol.45 , pp. 1958-1961
    • Mashek, D.G.1    Bornfeldt, K.E.2    Coleman, R.A.3
  • 18
    • 0034232476 scopus 로고    scopus 로고
    • Xenobiotic-coa ligases: Kinetic and molecular characterization
    • Knights KM, Drogemiller CJ. Xenobiotic-CoA Ligases: kinetic and Molecular Characterization. Curr Drug Metab 2000;1:49-66
    • (2000) Curr Drug Metab , vol.1 , pp. 49-66
    • Knights, K.M.1    Drogemiller, C.J.2
  • 19
    • 0029810456 scopus 로고    scopus 로고
    • Purification and characterization of a medium chain acyl-coenzyme A synthetase
    • Kasuya F, Igarashi K, Fukui M, Nokihara K. Purification and characterization of a medium chain acyl-coenzyme A synthetase. Drug Metab Dispos 1996;24(8):879-83
    • (1996) Drug Metab Dispos , vol.24 , Issue.8 , pp. 879-883
    • Kasuya, F.1    Igarashi, K.2    Fukui, M.3    Nokihara, K.4
  • 20
    • 0015060861 scopus 로고
    • Evidence for a medium-chain fatty acid: Coenzyme A ligase (adenosine monophosphate) that activates salicylate
    • Killinberg PG, Davidson ED, Webster LT. Evidence for a medium-chain fatty acid: coenzyme A ligase (adenosine monophosphate) that activates salicylate. Mol Pharmacol 1971;7:260-8
    • (1971) Mol Pharmacol , vol.7 , pp. 260-268
    • Killinberg, P.G.1    Davidson, E.D.2    Webster, L.T.3
  • 21
    • 0025949091 scopus 로고
    • Effect of carboxylic acid xenobiotics and their metabolites on the activity of carnitine acyltransferases
    • Vessey DA, Chen W, Ramsay RR. Effect of carboxylic acid xenobiotics and their metabolites on the activity of carnitine acyltransferases. Biochem J 1991;279:895-7
    • (1991) Biochem J , vol.279 , pp. 895-897
    • Vessey, D.A.1    Chen, W.2    Ramsay, R.R.3
  • 22
    • 0030338661 scopus 로고    scopus 로고
    • Interaction of salicylate and ibuprofen with the carboxylic acid: CoA ligases from bovine liver mitochondria
    • Vessey DA, Hu J, Kelley M. Interaction of salicylate and ibuprofen with the carboxylic acid: coA ligases from bovine liver mitochondria. J Biochem Toxicol 1996;11(2):73-8
    • (1996) J Biochem Toxicol , vol.11 , Issue.2 , pp. 73-78
    • Vessey, D.A.1    Hu, J.2    Kelley, M.3
  • 23
    • 84855872291 scopus 로고    scopus 로고
    • Central role of mitochondria in drug-induced liver injury
    • Pessayre D, Fromenty B, Berson A, et al. Central role of mitochondria in drug-induced liver injury. Drug Metab Rev 2012;44(1):34-87
    • (2012) Drug Metab Rev , vol.44 , Issue.1 , pp. 34-87
    • Pessayre, D.1    Fromenty, B.2    Berson, A.3
  • 24
    • 0029421074 scopus 로고
    • Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid: CoA ligases with activity toward xenobiotics
    • Vessey DA, Hu J. Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid: coA ligases with activity toward xenobiotics. J Biochem Toxicol 1995;10(6):329-37
    • (1995) J Biochem Toxicol , vol.10 , Issue.6 , pp. 329-337
    • Vessey, D.A.1    Hu, J.2
  • 25
    • 0035395856 scopus 로고    scopus 로고
    • Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/mediumchain fatty acid: CoA ligase
    • Vessey DA, Kelley M. Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/mediumchain fatty acid:coA ligase. Biochem J 2001;357:283-8
    • (2001) Biochem J , vol.357 , pp. 283-288
    • Vessey, D.A.1    Kelley, M.2
  • 26
    • 37249092959 scopus 로고    scopus 로고
    • Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome
    • Watkins PA, Maiguel D, Jia Z, Pevsner J. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. J Lipid Res 2007;48:2736-50
    • (2007) J Lipid Res , vol.48 , pp. 2736-2750
    • Watkins, P.A.1    Maiguel, D.2    Jia, Z.3    Pevsner, J.4
  • 27
    • 0032806660 scopus 로고    scopus 로고
    • Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short-and medium-chain fatty acids and xenobiotic carboxylic acids
    • Vessey DA, Kelley M, Warren RS. Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short-and medium-chain fatty acids and xenobiotic carboxylic acids. Biochim Biophys Acta 1999;1428:455-62
    • (1999) Biochim Biophys Acta , vol.1428 , pp. 455-462
    • Vessey, D.A.1    Kelley, M.2    Warren, R.S.3
  • 28
    • 0037247845 scopus 로고    scopus 로고
    • Isolation, Sequencing, and Expression of a cDNA for the HXM-A Form of Xenobiotic/Medium-Chain Fatty Acid: CoA Ligase from Human Liver Mitochondria
    • Vessey DA, Lau E, Kelley M, Warren RS. Isolation, Sequencing, and Expression of a cDNA for the HXM-A Form of Xenobiotic/Medium-Chain Fatty Acid:coA Ligase from Human Liver Mitochondria. J Biochem Mol Toxicol 2003;17(1):1-6
    • (2003) J Biochem Mol Toxicol , vol.17 , Issue.1 , pp. 1-6
    • Vessey, D.A.1    Lau, E.2    Kelley, M.3    Warren, R.S.4
  • 29
    • 0033961939 scopus 로고    scopus 로고
    • Difference of the liver and kidney in glycine conjugation of ortho-substituted benzoic acids
    • Kasuya F, Yamaoka Y, Osawa E, et al. Difference of the liver and kidney in glycine conjugation of ortho-substituted benzoic acids. Chem Biol Interact 2000;125:39-50
    • (2000) Chem Biol Interact , vol.125 , pp. 39-50
    • Kasuya, F.1    Yamaoka, Y.2    Osawa, E.3
  • 30
    • 0028214470 scopus 로고
    • The relationship between mitochondrial activation and toxicity of some substituted carboxylic acids
    • Yao KW, Mao LF, Luo MJ, Schulz H. The relationship between mitochondrial activation and toxicity of some substituted carboxylic acids. Chem Biol Interact 1994;90(3):225-34
    • (1994) Chem Biol Interact , vol.90 , Issue.3 , pp. 225-234
    • Yao, K.W.1    Mao, L.F.2    Luo, M.J.3    Schulz, H.4
  • 31
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
    • A very good introduction to hepatotoxicity resulting from inhibition of mitochondrial b-oxidation. Explains how some pharmaceuticals cause CoASH sequestration and consequences thereof
    • Fromenty B, Pessayre D. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther 1995;67(1):101-54 . A very good introduction to hepatotoxicity resulting from inhibition of mitochondrial b-oxidation. Explains how some pharmaceuticals cause CoASH sequestration and consequences thereof.
    • (1995) Pharmacol Ther , vol.67 , Issue.1 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 32
    • 0026091257 scopus 로고
    • Metabolic effects of pivalate in isolated rat hepatocytes
    • Ruff LJ, Brass EP. Metabolic effects of pivalate in isolated rat hepatocytes. Toxicol Appl Pharmacol 1991;110(2):295-302
    • (1991) Toxicol Appl Pharmacol , vol.110 , Issue.2 , pp. 295-302
    • Ruff, L.J.1    Brass, E.P.2
  • 33
    • 79952702137 scopus 로고    scopus 로고
    • Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver
    • Begriche K, Massart J, Robin MA, et al. Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 2011;54:773-94
    • (2011) J Hepatol , vol.54 , pp. 773-794
    • Begriche, K.1    Massart, J.2    Robin, M.A.3
  • 34
    • 79958206937 scopus 로고    scopus 로고
    • Sirtuins, aging, and medicine
    • Guarente L. Sirtuins, aging, and medicine. N Engl J Med 2011;364:2235-44
    • (2011) N Engl J Med , vol.364 , pp. 2235-2244
    • Guarente, L.1
  • 35
    • 0025880345 scopus 로고
    • Alteration of urinary carnitine profile induced by benzoate administration
    • Sakuma T. Alteration of urinary carnitine profile induced by benzoate administration. Arch Dis Child 1991;66:873-5
    • (1991) Arch Dis Child , vol.66 , pp. 873-875
    • Sakuma, T.1
  • 36
    • 0029974447 scopus 로고    scopus 로고
    • Chronic sodium benzoate therapy in children with inborn errors of urea synthesis: Effect on carnitine metabolism and ammonia nitrogen removal
    • Feoli-Fonseca JC, Lambert M, Mitchell G, et al. Chronic sodium benzoate therapy in children with inborn errors of urea synthesis: effect on carnitine metabolism and ammonia nitrogen removal. Biochem Mol Med 1996;57:31-6
    • (1996) Biochem Mol Med , vol.57 , pp. 31-36
    • Feoli-Fonseca, J.C.1    Lambert, M.2    Mitchell, G.3
  • 37
    • 0002911516 scopus 로고    scopus 로고
    • Part 9: Organic acids. Chapter 94: Disorders of propionate and methylmalonate metabolism
    • In: Vale D, Beaudet AL, Vogelstein B, et al., editors. McGraw Hill, New York
    • Fenton WA, Gravel RA, Rosenblatt DS. Part 9: organic acids. Chapter 94: disorders of propionate and methylmalonate metabolism. In: Vale D, Beaudet AL, Vogelstein B, et al., editors, The online metabolic and molecular bases of inherited diseases. McGraw Hill, New York; 2013
    • (2013) The Online Metabolic and Molecular Bases of Inherited Diseases
    • Fenton, W.A.1    Gravel, R.A.2    Rosenblatt, D.S.3
  • 38
    • 0028059889 scopus 로고
    • Medium-chain fatty acids as short-term regulators of hepatic lipogenesis
    • Geelen MJH. Medium-chain fatty acids as short-term regulators of hepatic lipogenesis. Biochem J 1994;302:141-6
    • (1994) Biochem J , vol.302 , pp. 141-146
    • Geelen, M.J.H.1
  • 39
    • 0035514033 scopus 로고    scopus 로고
    • Reye syndrome-insights on causation and prognosis
    • Glasgow JFT, Middleton B. Reye syndrome-insights on causation and prognosis. Arch Dis Child 2001;85:351-3
    • (2001) Arch Dis Child , vol.85 , pp. 351-353
    • Glasgow, J.F.T.1    Middleton, B.2
  • 40
    • 34249869507 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel human glycine N-acyltransferase gene GLYAT1, which activates transcriptional activity of HSE pathway
    • Zhang H, Lang Q, Li J, et al. Molecular cloning and characterization of a novel human glycine N-acyltransferase gene GLYAT1, which activates transcriptional activity of HSE pathway. Int J Mol Sci 2007;8:433-44
    • (2007) Int J Mol Sci , vol.8 , pp. 433-444
    • Zhang, H.1    Lang, Q.2    Li, J.3
  • 41
    • 84864125549 scopus 로고    scopus 로고
    • The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
    • Hunt MC, Siponen MI, Alexson SEH. The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism. Biochim Biophys Acta 2012;1822:1397-410
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 1397-1410
    • Hunt, M.C.1    Siponen, M.I.2    Alexson, S.E.H.3
  • 42
    • 0016062830 scopus 로고
    • The specificity of glycine-N-acylase and acylglycine excretion in the organicacidaemias
    • Bartlett K, Gompertz D. The specificity of glycine-N-acylase and acylglycine excretion in the organicacidaemias. Biochem Med 1974;10(1):15-23
    • (1974) Biochem Med , vol.10 , Issue.1 , pp. 15-23
    • Bartlett, K.1    Gompertz, D.2
  • 43
    • 0034039710 scopus 로고    scopus 로고
    • Evaluation of urinary acylglycines by electrospray tandem mass spectrometry in mitochondrial energy metabolism defects and organic acidurias
    • Bonafe L, Troxler H, Kuster T, et al. Evaluation of urinary acylglycines by electrospray tandem mass spectrometry in mitochondrial energy metabolism defects and organic acidurias. Mol Genet Metab 2000;69:302-11
    • (2000) Mol Genet Metab , vol.69 , pp. 302-311
    • Bonafe, L.1    Troxler, H.2    Kuster, T.3
  • 44
    • 0037098870 scopus 로고    scopus 로고
    • The metabolic fate of dietary polyphenols in humans
    • Rechner AR, Kuhnle G, Bremner P, et al. The metabolic fate of dietary polyphenols in humans. Free Radic Biol Med 2002;33(2):220-35
    • (2002) Free Radic Biol Med , vol.33 , Issue.2 , pp. 220-235
    • Rechner, A.R.1    Kuhnle, G.2    Bremner, P.3
  • 45
    • 77957731348 scopus 로고    scopus 로고
    • Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Chron's disease
    • Williams HRT, Cox IJ, Walker DG, et al. Differences in gut microbial metabolism are responsible for reduced hippurate synthesis in Chron's disease. BMC Gastroenterol 2010;10:108
    • (2010) BMC Gastroenterol , vol.10 , pp. 108
    • Williams, H.R.T.1    Cox, I.J.2    Walker, D.G.3
  • 46
    • 0034892506 scopus 로고    scopus 로고
    • Salicylic acid: A link between aspirin, diet and the prevention of colorectal cancer
    • Paterson JR, Lawrence JR. Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer. Q J Med 2001;94:445-8
    • (2001) Q J Med , vol.94 , pp. 445-448
    • Paterson, J.R.1    Lawrence, J.R.2
  • 47
    • 0028862228 scopus 로고
    • Glycine conjugation of Para-Aminobenzoic Acid (PABA): A quantitative test of liver function
    • Furuya KN, Durie PR, Roberts EA, et al. Glycine conjugation of Para-Aminobenzoic Acid (PABA): a quantitative test of liver function. Clin Biochem 1995;28(5):531-40
    • (1995) Clin Biochem , vol.28 , Issue.5 , pp. 531-540
    • Furuya, K.N.1    Durie, P.R.2    Roberts, E.A.3
  • 49
    • 1042290482 scopus 로고    scopus 로고
    • Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
    • Dorne JLCM, Walton K, Renwick AG. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation). Food Chem Toxicol 2004;42:397-421
    • (2004) Food Chem Toxicol , vol.42 , pp. 397-421
    • Dorne, J.L.C.M.1    Walton, K.2    Renwick, A.G.3
  • 50
    • 0014216790 scopus 로고
    • The isolation and identification of N-isovalerylglycine from urine of patients with isovaleric acidemia
    • Tanaka K, Isselbacher KJ. The isolation and identification of N-isovalerylglycine from urine of patients with isovaleric acidemia. J Biol Chem 1967;242(12):2966-72
    • (1967) J Biol Chem , vol.242 , Issue.12 , pp. 2966-2972
    • Tanaka, K.1    Isselbacher, K.J.2
  • 51
    • 0013923852 scopus 로고
    • Isovaleric acidemia: A new genetic defect of leucine metabolism
    • Tanaka K, Budd WA, Efron ML, Isselbacher KJ. Isovaleric acidemia: a new genetic defect of leucine metabolism. Biochemistry 1966;56:236-42
    • (1966) Biochemistry , vol.56 , pp. 236-242
    • Tanaka, K.1    Budd, W.A.2    Efron, M.L.3    Isselbacher, K.J.4
  • 52
    • 0036304671 scopus 로고    scopus 로고
    • Branched-chain organic acidurias
    • Ogier DB, Saudubray JM. Branched-chain organic acidurias. Semin Neonatol 2002;7(1):65-74
    • (2002) Semin Neonatol , vol.7 , Issue.1 , pp. 65-74
    • Ogier, D.B.1    Saudubray, J.M.2
  • 53
    • 0016292771 scopus 로고
    • Inborn errors of organic acid metabolism
    • Gompertz D. Inborn errors of organic acid metabolism. Clin Endocrinol Metab 1974;3:107-130
    • (1974) Clin Endocrinol Metab , vol.3 , pp. 107-130
    • Gompertz, D.1
  • 54
    • 0017811720 scopus 로고
    • Formation of Ndicarboxyl-mono-glycines catalyzed bt glycine-N-Acylase
    • Gron I, Gregersen N, Kolvraa S, Rasmussen K. Formation of Ndicarboxyl-mono-glycines catalyzed bt glycine-N-Acylase. Biochem Med 1978;19:133-40
    • (1978) Biochem Med , vol.19 , pp. 133-140
    • Gron, I.1    Gregersen, N.2    Kolvraa, S.3    Rasmussen, K.4
  • 55
    • 0016891208 scopus 로고
    • Therapeutic effects of glycine in isovaleric acidemia
    • Krieger I, Tanaka K. Therapeutic effects of glycine in isovaleric acidemia. Pediatr Res 1976;10:25-9
    • (1976) Pediatr Res , vol.10 , pp. 25-29
    • Krieger, I.1    Tanaka, K.2
  • 56
    • 84872485614 scopus 로고    scopus 로고
    • Clinical variability of isovaleric acidemia in a genetically homogeneous population
    • Dercksen M, Duran M, Ijlst L, et al. Clinical variability of isovaleric acidemia in a genetically homogeneous population. J Inherit Metab Dis 2012;2012:17
    • (2012) J Inherit Metab Dis , vol.2012 , pp. 17
    • Dercksen, M.1    Duran, M.2    Ijlst, L.3
  • 57
    • 0003237157 scopus 로고    scopus 로고
    • Part 9: Organic acids Chapter 93: Branched chain organic acidurias
    • In: Vale D, Beaudet AL, Vogelstein B, et al., editors McGraw Hill, New York
    • Sweetman L, Williams JC. Part 9: organic acids Chapter 93: branched chain organic acidurias. In: Vale D, Beaudet AL, Vogelstein B, et al., editors, The online metabolic and molecular bases of inherited diseases; McGraw Hill, New York; 2013
    • (2013) The Online Metabolic and Molecular Bases of Inherited Diseases
    • Sweetman, L.1    Williams, J.C.2
  • 58
    • 0018787092 scopus 로고
    • Benzoyl-coenzyme A: Glycine N-acyltransferase and phenylacetyl-coenzyme A: Glycine N-acyltransferase from bovine liver mitochondria
    • Nandi DL, Lucas SV, Webster LT Jr. Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization. J Biol Chem 1979;254(15):7230-7
    • (1979) Purification and Characterization. J Biol Chem , vol.254 , Issue.15 , pp. 7230-7237
    • Nandi, D.L.1    Lucas, S.V.2    Webster Jr., L.T.3
  • 59
    • 0027406059 scopus 로고
    • Dependence of glycine conjugation on availability of glycine: Role of the glycine cleavage system
    • Gregus Z, Fekete T, Varga F, Klaassen CD. Dependence of glycine conjugation on availability of glycine: role of the glycine cleavage system. Xenobiotica 1993;23(2):141-53
    • (1993) Xenobiotica , vol.23 , Issue.2 , pp. 141-153
    • Gregus, Z.1    Fekete, T.2    Varga, F.3    Klaassen, C.D.4
  • 60
    • 0033631608 scopus 로고    scopus 로고
    • The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase
    • van der Westhuizen FH, Pretorius PJ, Erasmus E. The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase. J Biochem Mol Toxicol 2000;14(2):102-9
    • (2000) J Biochem Mol Toxicol , vol.14 , Issue.2 , pp. 102-109
    • Van Der Westhuizen, F.H.1    Pretorius, P.J.2    Erasmus, E.3
  • 61
    • 23044444836 scopus 로고    scopus 로고
    • Identification of 19 new metabolites induced by abnormal amino acid conjugation in isovaleric acidemia
    • Loots D, Erasmus E, Mienie LJ. Identification of 19 new metabolites induced by abnormal amino acid conjugation in isovaleric acidemia. Clin Chem 2005;51(8):1510-12
    • (2005) Clin Chem , vol.51 , Issue.8 , pp. 1510-1512
    • Loots, D.1    Erasmus, E.2    Mienie, L.J.3
  • 62
    • 0002474371 scopus 로고
    • Conjugation reactions in the newborn infant: The metabolism of para-aminobenzoic acid
    • Vest MF, Salzberg R. Conjugation reactions in the newborn infant: the metabolism of para-aminobenzoic acid. Arch Dis Childh 1965;40:97-105
    • (1965) Arch Dis Childh , vol.40 , pp. 97-105
    • Vest, M.F.1    Salzberg, R.2
  • 63
  • 64
    • 0027765518 scopus 로고
    • Conjugation of benzoic acid with glycine in human liver and kidney: A study on the interindividual variability
    • Temellini A, Mogavero S, Giulianotti PC, et al. Conjugation of benzoic acid with glycine in human liver and kidney: a study on the interindividual variability. Xenobiotica 1993;23(12):1427-33
    • (1993) Xenobiotica , vol.23 , Issue.12 , pp. 1427-1433
    • Temellini, A.1    Mogavero, S.2    Giulianotti, P.C.3
  • 65
    • 0028867666 scopus 로고
    • Preliminary assessment of glycine conjugation of para-aminobenzoic acid as a quantitative test of liver function
    • Duffy LF, Kerzner B, Seeff L, et al. Preliminary assessment of glycine conjugation of para-aminobenzoic acid as a quantitative test of liver function. Clin Biochem 1995;28(5):527-30
    • (1995) Clin Biochem , vol.28 , Issue.5 , pp. 527-530
    • Duffy, L.F.1    Kerzner, B.2    Seeff, L.3
  • 66
    • 1842855008 scopus 로고    scopus 로고
    • Glycine conjugation of para-aminobenzoic acid (PABA): A pilot study of a novel prognostic test in acute liver failure in children
    • Lebel S, Nakamachi Y, Hemming A, et al. Glycine conjugation of para-aminobenzoic acid (PABA): a pilot study of a novel prognostic test in acute liver failure in children. J Pediatr Gastroenterol Nutr 2003;36(1):62-71
    • (2003) J Pediatr Gastroenterol Nutr , vol.36 , Issue.1 , pp. 62-71
    • Lebel, S.1    Nakamachi, Y.2    Hemming, A.3
  • 67
    • 0027768968 scopus 로고
    • Effect of valproic acid on glycine conjugation of benzoic acid
    • Gregus Z, Fekete T, Varga F, Klaassen CD. Effect of valproic acid on glycine conjugation of benzoic acid. J Pharmacol Exp Ther 1993;267(3):1068-75
    • (1993) J Pharmacol Exp Ther , vol.267 , Issue.3 , pp. 1068-1075
    • Gregus, Z.1    Fekete, T.2    Varga, F.3    Klaassen, C.D.4
  • 68
    • 84859874537 scopus 로고    scopus 로고
    • Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma
    • Matsuo M, Terai K, Kameda N, et al. Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N- acyltransferase in human hepatocellular carcinoma. Biochem Biophys Res Commun 2012;420(4):901-6
    • (2012) Biochem Biophys Res Commun , vol.420 , Issue.4 , pp. 901-906
    • Matsuo, M.1    Terai, K.2    Kameda, N.3
  • 69
    • 84861420588 scopus 로고    scopus 로고
    • Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
    • Jain M, Nilsson R, Sharma S, et al. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012;336(6084):1040-4
    • (2012) Science , vol.336 , Issue.6084 , pp. 1040-1044
    • Jain, M.1    Nilsson, R.2    Sharma, S.3
  • 70
    • 0032530853 scopus 로고    scopus 로고
    • The crystal structure of human cytosolic serine hydroxymethyltransferase: A target for cancer chemotherapy
    • Renwick SB, Snell K, Baumann U. The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy. Structure 1998;6(9):1105-16
    • (1998) Structure , vol.6 , Issue.9 , pp. 1105-1116
    • Renwick, S.B.1    Snell, K.2    Baumann, U.3
  • 71
    • 84874766536 scopus 로고    scopus 로고
    • Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study
    • Guo Y, Zhang L, Liu Y, et al. Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study. Hum Genet 2013;132(2):189-99
    • (2013) Hum Genet , vol.132 , Issue.2 , pp. 189-199
    • Guo, Y.1    Zhang, L.2    Liu, Y.3
  • 72
    • 0022632821 scopus 로고
    • Acyl-CoA: Glycine N-acyltransferase: In vitro studies on the glycine conjugation of straight-and branched-chained acyl-CoA esters in human liver
    • Gregersen N, Kolvraa S, Mortensen PB. Acyl-CoA: glycine N-acyltransferase: in vitro studies on the glycine conjugation of straight-and branched-chained acyl-CoA esters in human liver. Biochem Med Metab Biol 1986;35(2):210-18
    • (1986) Biochem Med Metab Biol , vol.35 , Issue.2 , pp. 210-218
    • Gregersen, N.1    Kolvraa, S.2    Mortensen, P.B.3
  • 73
    • 0025445888 scopus 로고
    • The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA Nacyltransferases from bovine liver mitochondria
    • Kelley M, Vessey D. The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA Nacyltransferases from bovine liver mitochondria. J Biochem Toxicol 1990;5:125-35
    • (1990) J Biochem Toxicol , vol.5 , pp. 125-135
    • Kelley, M.1    Vessey, D.2
  • 74
    • 0028446576 scopus 로고
    • Characterization of the acyl-CoA: Amino acid N-acyltransferases from primate liver mitochondria
    • Kelley M, Vessey D. Characterization of the acyl-CoA: amino acid N-acyltransferases from primate liver mitochondria. J Biochem Toxicol 1994;9:153-8
    • (1994) J Biochem Toxicol , vol.9 , pp. 153-158
    • Kelley, M.1    Vessey, D.2
  • 75
    • 0027618423 scopus 로고
    • Isolation and characterization of mitochondrial acyl-CoA: Glycine N-acyltransferases from kidney
    • Kelley M, Vessey DA. Isolation and characterization of mitochondrial acyl-CoA: glycine N-acyltransferases from kidney. J Biochem Toxicol 1993;8(2):63-9
    • (1993) J Biochem Toxicol , vol.8 , Issue.2 , pp. 63-69
    • Kelley, M.1    Vessey, D.A.2
  • 76
    • 0022476572 scopus 로고
    • Acyl-CoA: Glycine N-acyltransferase: Organelle localization and affinity toward straightand branched-chained acyl-CoA esters in rat liver
    • Kolvraa S, Gregersen N. Acyl-CoA: glycine N-acyltransferase: organelle localization and affinity toward straightand branched-chained acyl-CoA esters in rat liver. Biochem Med Metab Biol 1986;36(1):98-105
    • (1986) Biochem Med Metab Biol , vol.36 , Issue.1 , pp. 98-105
    • Kolvraa, S.1    Gregersen, N.2
  • 77
    • 0017385660 scopus 로고
    • Photoaffinity labeling of acyl-coenzyme A: Glycine N-acyltransferase with p-azidobenzoyl-coenzyme A
    • Lau EP, Haley BE, Barden RE. Photoaffinity labeling of acyl-coenzyme A:glycine N-acyltransferase with p-azidobenzoyl-coenzyme A. Biochemistry 1977;16(12):2581-5
    • (1977) Biochemistry , vol.16 , Issue.12 , pp. 2581-2585
    • Lau, E.P.1    Haley, B.E.2    Barden, R.E.3
  • 78
    • 0028658378 scopus 로고
    • Purification to homogeneity of mitochondrial acyl coa: Glycine n-acyltransferase from human liver
    • Mawal YR, Qureshi IA. Purification to homogeneity of mitochondrial acyl coa: glycine n-acyltransferase from human liver. Biochem Biophys Res Commun 1994;205(2):1373-9
    • (1994) Biochem Biophys Res Commun , vol.205 , Issue.2 , pp. 1373-1379
    • Mawal, Y.R.1    Qureshi, I.A.2
  • 79
    • 0001223386 scopus 로고
    • Glycine Nacylase: Purification and properties
    • Schachter D, Taggart JV. Glycine Nacylase: purification and properties. J Biol Chem 1954;208(1):263-75
    • (1954) J Biol Chem , vol.208 , Issue.1 , pp. 263-275
    • Schachter, D.1    Taggart, J.V.2
  • 80
    • 0031616519 scopus 로고    scopus 로고
    • Determination of the Sequence of the arylacetyl acyl-CoA: Amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA: Amino acid N-acyltransferase
    • Vessey DA, Lau EP. Determination of the Sequence of the arylacetyl acyl-CoA: amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA:amino acid N-acyltransferase. J Biochem Mol Toxicol 1998;12(5):275-9
    • (1998) J Biochem Mol Toxicol , vol.12 , Issue.5 , pp. 275-279
    • Vessey, D.A.1    Lau, E.P.2
  • 81
    • 0017066187 scopus 로고
    • Identification of separate acyl-CoA: Glycine and acyl-CoA: L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man
    • Webster LT, Siddiqui UA, Lucas SV, et al. Identification of separate acyl-CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man. J Biol Chem 1976;251(11):3352-8
    • (1976) J Biol Chem , vol.251 , Issue.11 , pp. 3352-3358
    • Webster, L.T.1    Siddiqui, U.A.2    Lucas, S.V.3
  • 82
    • 77049162004 scopus 로고
    • Product inhibition in the clygine N-acylase reaction
    • Schachter D, Taggart JV. Product inhibition in the clygine N-acylase reaction. J Biol Chem 1954;211(1):271-8
    • (1954) J Biol Chem , vol.211 , Issue.1 , pp. 271-278
    • Schachter, D.1    Taggart, J.V.2
  • 83
    • 0028196606 scopus 로고
    • Exposure of workers to a mixture of toluene and xylenes
    • Huang M, Jin C, Liu Y, et al. Exposure of workers to a mixture of toluene and xylenes. I metabolism. Occup Environ Med 1994;51:42-6
    • (1994) I Metabolism. Occup Environ Med , vol.51 , pp. 42-46
    • Huang, M.1    Jin, C.2    Liu, Y.3
  • 84
    • 84872500403 scopus 로고    scopus 로고
    • Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase
    • van der Sluis R, Badenhorst CPS, van der Westhuizen FH, van Dijk AA. Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase. Gene 2013;515:447-53
    • (2013) Gene , vol.515 , pp. 447-453
    • Van Der Sluis, R.1    Badenhorst, C.P.S.2    Van Der Westhuizen, F.H.3    Van Dijk, A.A.4
  • 85
    • 84856020209 scopus 로고    scopus 로고
    • Enzymatic characterization and elucidation of the catalytic mechanism of a recombinant bovine glycine N-acyltransferase
    • Badenhorst CPS, Jooste M, van Dijk AA. Enzymatic characterization and elucidation of the catalytic mechanism of a recombinant bovine glycine N-acyltransferase. Drug Metab Dispos 2012;40(2):346-52
    • (2012) Drug Metab Dispos , vol.40 , Issue.2 , pp. 346-352
    • Badenhorst, C.P.S.1    Jooste, M.2    Van Dijk, A.A.3
  • 86
    • 78249243880 scopus 로고    scopus 로고
    • Genetic polymorphisms of Glycine N-acyltransferase (GLYAT) in a French Caucasian population
    • Lino Cardenas CL, Bourgine J, Cauffiez C, et al. Genetic polymorphisms of Glycine N-acyltransferase (GLYAT) in a French Caucasian population. Xenobiotica 2010;40(12):853-61
    • (2010) Xenobiotica , vol.40 , Issue.12 , pp. 853-861
    • Lino Cardenas, C.L.1    Bourgine, J.2    Cauffiez, C.3
  • 87
    • 67649321880 scopus 로고    scopus 로고
    • Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals
    • Yamamoto A, Nonen S, Fukuda T, et al. Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals. Drug Metab Pharmacokinet 2009;24(1):114-17
    • (2009) Drug Metab Pharmacokinet , vol.24 , Issue.1 , pp. 114-117
    • Yamamoto, A.1    Nonen, S.2    Fukuda, T.3
  • 88
    • 77955792986 scopus 로고    scopus 로고
    • Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans
    • Waluk DP, Schultz N, Hunt MC. Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans. FASEB J 2010;24(8):2795-803
    • (2010) FASEB J , vol.24 , Issue.8 , pp. 2795-2803
    • Waluk, D.P.1    Schultz, N.2    Hunt, M.C.3
  • 89
    • 84860864004 scopus 로고    scopus 로고
    • Reversible lysine acetylation regulates activity of human glycine N-acyltransferase-like 2 (hGLYATL2): Implications for production of glycine-conjugated signaling molecules
    • Waluk DP, Sucharski F, Sipos L, et al. Reversible lysine acetylation regulates activity of human glycine N-acyltransferase-like 2 (hGLYATL2): implications for production of glycine-conjugated signaling molecules. J Biol Chem 2012;287(20):16158-67
    • (2012) J Biol Chem , vol.287 , Issue.20 , pp. 16158-16167
    • Waluk, D.P.1    Sucharski, F.2    Sipos, L.3
  • 90
    • 14844282831 scopus 로고    scopus 로고
    • The expanding field of cannabimimetic and related lipid mediators
    • Bradshaw HB, Walker JM. The expanding field of cannabimimetic and related lipid mediators. Br J Pharmacol 2005;144:459-65
    • (2005) Br J Pharmacol , vol.144 , pp. 459-465
    • Bradshaw, H.B.1    Walker, J.M.2
  • 91
    • 77949890874 scopus 로고    scopus 로고
    • A weak link in metabolism: The metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis
    • Melendez-Hevia E, De Paz-Lugo P, Cornish-Bowden A, Cardenas ML. A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis. J Biosci 2009;34(6):853-72
    • (2009) J Biosci , vol.34 , Issue.6 , pp. 853-872
    • Melendez-Hevia, E.1    De Paz-Lugo, P.2    Cornish-Bowden, A.3    Cardenas, M.L.4
  • 92
    • 15944411011 scopus 로고    scopus 로고
    • Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply
    • Lewis RM, Godfrey KM, Jackson AA, et al. Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply. J Clin Endocrinol Metab 2005;90(3):1594-8
    • (2005) J Clin Endocrinol Metab , vol.90 , Issue.3 , pp. 1594-1598
    • Lewis, R.M.1    Godfrey, K.M.2    Jackson, A.A.3
  • 93
    • 0025896988 scopus 로고
    • The glycine story
    • Jackson AA. The glycine story. Eur J Clin Nutr 1991;45(2):59-65
    • (1991) Eur J Clin Nutr , vol.45 , Issue.2 , pp. 59-65
    • Jackson, A.A.1
  • 94
    • 0015719962 scopus 로고
    • The role pf substrates for glycine acyltransferase in the reversal of chemically induced porphyria in the rat
    • Piper WN, Condie LW, Tephly TR. The role pf substrates for glycine acyltransferase in the reversal of chemically induced porphyria in the rat. Arch Biochem Biophy 1973;159:671-7
    • (1973) Arch Biochem Biophy , vol.159 , pp. 671-677
    • Piper, W.N.1    Condie, L.W.2    Tephly, T.R.3
  • 95
    • 0033393438 scopus 로고    scopus 로고
    • Benzoylserine and benzoylthreonine in propionic acidaemia treated with sodium benzoate
    • van der Westhuizen FH, Terblanche E, Mienie LJ. Benzoylserine and benzoylthreonine in propionic acidaemia treated with sodium benzoate. SAMJ 1999;89(12):125-7
    • (1999) SAMJ , vol.89 , Issue.12 , pp. 125-127
    • Van Der Westhuizen, F.H.1    Terblanche, E.2    Mienie, L.J.3
  • 96
    • 0030862155 scopus 로고    scopus 로고
    • Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in saccharomyces cerevisiae
    • Kastanos EK, Woldman YY, Appling DR. Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in saccharomyces cerevisiae. Biochemistry 1997;36:14956-64
    • (1997) Biochemistry , vol.36 , pp. 14956-14964
    • Kastanos, E.K.1    Woldman, Y.Y.2    Appling, D.R.3
  • 98
    • 79956348319 scopus 로고    scopus 로고
    • Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)
    • Kimura I, Inoue D, Maeda T, et al. Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41). PNAS 2011;108(19):8030-5
    • (2011) PNAS , vol.108 , Issue.19 , pp. 8030-8035
    • Kimura, I.1    Inoue, D.2    Maeda, T.3
  • 99
    • 0035080201 scopus 로고    scopus 로고
    • Isolation and preliminary characterization of the medium-chain fatty acid: CoA ligase responsible for activation of short-and medium-chain fatty acids in colonic mucosa from swine
    • Vessey DA. Isolation and preliminary characterization of the medium-chain fatty acid:coA ligase responsible for activation of short-and medium-chain fatty acids in colonic mucosa from swine. Dig Dis Sci 2001;46:438-42
    • (2001) Dig Dis Sci , vol.46 , pp. 438-442
    • Vessey, D.A.1
  • 101
    • 84858590812 scopus 로고    scopus 로고
    • Gut microbiota: Next frontier in understanding human health and development of biotherapeutics
    • Prakash S, Rodes L, Coussa-Charley M, Tomaro-Duchesneau C. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics 2011;5:71-86
    • (2011) Biologics , vol.5 , pp. 71-86
    • Prakash, S.1    Rodes, L.2    Coussa-Charley, M.3    Tomaro-Duchesneau, C.4


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